1.Prospective study for prevention of thrombophlebitis of indwelling central venous catheters.
Myoung Jung KIM ; Tae Il MOON ; Kwon Mook CHAE
Journal of the Korean Surgical Society 1991;40(2):235-242
No abstract available.
Central Venous Catheters*
;
Prospective Studies*
;
Thrombophlebitis*
2.Clinical Observation on Nonspecific Female Urethritis.
Korean Journal of Urology 1971;12(1):71-77
No abstract available.
Female*
;
Humans
;
Urethritis*
3.Clinical Application of Shake test od Gastric Aspiretes for the Prediction od Respiratory Distress Syndrome in the Newborn infants.
In Sang JEON ; Hann TCHAH ; Myoung Jae CHOI ; Beyng Il KIM ; Jung Hwan CHOI ; Chong Ku YUN
Journal of the Korean Pediatric Society 1989;32(3):349-358
No abstract available.
Humans
;
Infant, Newborn*
4.Effects of Antioxidant on Reduction of Hindlimb Muscle Atrophy Induced by Cisplatin in Rats.
Journal of Korean Academy of Nursing 2014;44(4):371-380
PURPOSE: The purpose of this study was to examine the effects of Cu/Zn SOD on reduction of hindlimb muscular atrophy induced by cisplatin in rats. METHODS: Forty-two rats were assigned to three groups; control group, Cisplatin (CDDP) group and cisplatin with Cu/Zn SOD (CDDP-SOD) group. At day 35 hindlimb muscles were dissected. Food intake, activity, withdrawal threshold, muscle weight, and Type I, II fiber cross-sectional area (CSA) of dissected muscles were measured. Relative SOD activity and expression of MHC and phosphorylated Akt, ERK were measured after dissection. RESULTS: Muscle weight and Type I, II fiber CSA of hindlimb muscles in the CDDP group were significantly less than the control group. Muscle weight and Type I, II fiber CSA of hindlimb muscles, food intake, activity, and withdrawal thresholds of the CDDP-SOD group were significantly greater than the CDDP group. There were no significant differences in relative SOD activities of hindlimb muscles between the CDDP-SOD and CDDP groups. MHC expression and phosphorylated Akt, ERK of hindlimb muscles in the CDDP-SOD group were significantly greater than the CDDP group. CONCLUSION: Cu/Zn SOD attenuates hindlimb muscular atrophy induced by cisplatin through increased food intake and activity. Increment of phosphorylated Akt, ERK may relate to attenuation of hindlimb muscular atrophy.
Animals
;
Body Weight/drug effects
;
Cisplatin/*toxicity
;
Disease Models, Animal
;
Extracellular Signal-Regulated MAP Kinases/metabolism
;
Hindlimb
;
Male
;
Muscle, Skeletal/*drug effects/enzymology/metabolism
;
Muscular Atrophy/*chemically induced/metabolism/pathology
;
Phosphorylation
;
Proto-Oncogene Proteins c-akt/metabolism
;
Rats
;
Rats, Sprague-Dawley
;
Recombinant Proteins/biosynthesis/genetics/pharmacology
;
Superoxide Dismutase/genetics/metabolism/pharmacology
;
Superoxides/metabolism
5.Effects of Unilateral Sciatic Nerve Injury on Unaffected Hindlimb Muscles of Rats.
Journal of Korean Academy of Nursing 2009;39(3):393-400
PURPOSE: The purpose of this study was to examine the effects of unilateral sciatic nerve injury on unaffected hindlimb muscles of rats. METHODS: Adult male Sprague-Dawley rats were assigned to one of three groups: control (C) group (n=10) that had no procedures, sham (S) group (n=10) that underwent sham left sciatic nerve transection, and sciatic nerve transection (SNT) group (n=9) that underwent left sciatic nerve transection. At 15 days rats were anesthetized, and the soleus, plantaris and gastrocnemius muscles were dissected. RESULTS: Muscle weight of the unaffected plantaris muscle in the SNT group was significantly lower than in the other two groups. Type II fiber cross-sectional areas of the unaffected plantaris and gastrocnemius muscles in the SNT group were significantly smaller than in the other two groups. The decrease of muscle weights and Type I, II fiber cross-sectional areas of the unaffected three muscles in the SNT group were significantly less than that of the affected three muscles. CONCLUSION: Hindlimb muscle atrophy occurs in the unaffected side after unilateral sciatic nerve injury, with changes in the plantaris and gastrocnemius muscle being more apparent than changes in the soleus muscle. These results have implications for nursing care, in the need to assess degree of muscle atrophy in unaffected muscles as well as affected muscles.
Animals
;
Body Weight
;
Eating
;
Hindlimb
;
Male
;
Muscle Fibers, Skeletal/*physiology
;
Muscle Weakness
;
Muscular Atrophy/*etiology/physiopathology
;
Rats
;
Rats, Sprague-Dawley
;
Sciatic Nerve/*injuries/physiology
6.Current Status of Deceased Donor Organ Recovery and Sharing in Korea.
Myoung Soo KIM ; Soon Il KIM ; Yu Seun KIM
Journal of the Korean Medical Association 2008;51(8):685-691
The first deceased donor organ (kidney) recovery and transplantation was performed in 1979. Since February 2000, deceased donor organ recovery and allocation have been performed exclusively by the direction of the Korean Network for Organ Sharing (KONOS), the governmental authority for organ transplantation in Korea. Herein, we review the annual incidence of deceased donor occurrence, transplantation statistics, and organ allocation status in the era of KONOS, and discuss about future directions for improved organ transplantation activities in Korea.
Humans
;
Incidence
;
Korea
;
Organ Transplantation
;
Tissue Donors
;
Transplants
7.Clinical experience on instep full-thickness skin grafts for reconstruction of the hand.
Jin Hwan KIM ; Myoung Soo SHIN ; Rong Min BAEK ; Heung Soo HAN ; Dong Il KIM ; Se Min BAEK
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1992;19(6):1077-1084
No abstract available.
Hand*
;
Skin*
;
Transplants*
8.Lymphocytic Hypophysitis Presenting with Diabetes Insipidus in a Man: Report of a case.
Woo Sung MOON ; Myoung Jae KANG ; Dong Geun LEE ; Hyung Il KIM ; Ho Yeul CHOI ; Sang Ho KIM
Korean Journal of Pathology 1996;30(6):528-532
Lymphocytic hypophysitis is an autoimmune disorder of the pituitary gland which usually occurs in a woman in the postpartum period. Diabetes insipidus is not a major clinical feature of this disorder. We report a case of a 22-year-old man with lymphocytic hypophysitis which presented with diabetes insipidus and also involved his cavernous sinus. This represents the seventh reported and the youngest case of a man with lymphocytic hypophysitis. A comparative study of all six male patients is also presented. We suggest diabetes insipidus should be added to the spectrum of clinical manifestations of this disorder.
Female
;
Male
;
Humans
9.Factors Affecting the First 3-year Quality of Graft Function after Live Donor Kidney Transplantation.
Myoung Soo KIM ; Yu Seun KIM ; Soon Il KIM ; Jang Il MOON ; Kyung Ock JEON ; Kiil PARK
Journal of the Korean Surgical Society 2000;58(6):789-801
PURPOSE: We designed this study to identify the risk factors affecting the quality of graft after live donor kidney transplantation. METHODS: The study cohort included 259 adult patients who had been followed up for an average of 37 months after transplantation. Cyclosporine (CsA) and steroids were used as main immunosuppressive agents. Seven variables [HLA match, numbers of acute rejection (AR) within post-transplant 1 year, blood type compatibility, use of anti-lymphocyte antibody, age of donor (DA), age of recipient, and the donor kidney weight to recipient body weight ratio (KW/BW)] were examined by multiple regression analysis during the first 3 years. Serum creatinine (Scr), creatinine clearance rate (Ccr) and the 24 hours urinary excretion of protein (24 UP) were used as parameters. RESULTS: AR, DA, or KW/BW independently affected the quality of graft function. Scr, Ccr, or 24 UP at post-transplant 1 year was strongly correlated with AR (p<0.0001, p=0.002, or p=0.002, respectively). However, Scr, Ccr, or 24 UP at post-transplant 3 years was strongly affected by KW/BW (p<0.0001, p<0.0001, or p=0.008, respectively) or DA (p<0.0001, p=0.001, or p=0.039, respectively). CONCLUSION: Non-immunologic factors independently affected the graft function through the study periods. The impact of non-immunologic factors on the function of the graft increased year by year. During renal allocation, KW/BW and DA should be included as reference indices to improve the long-term graft function.
Adult
;
Body Weight
;
Cohort Studies
;
Creatinine
;
Cyclosporine
;
Humans
;
Immunosuppressive Agents
;
Kidney Transplantation*
;
Kidney*
;
Risk Factors
;
Steroids
;
Tissue Donors*
;
Transplants*
10.Conversion Effect from Prednisone to Deflazacort in Diabetic Kidney Transplants.
Myoung Soo KIM ; Yu Seun KIM ; Seung Kil LIM ; Soon Il KIM ; Hae Kyung LEE ; Ki Il PARK
Korean Journal of Nephrology 1997;16(1):114-122
The blood sugar control has been a significant problem after transplantation. Cyclosporine is partly responsible for post-transplantation diabetes mellitus (PTDM), but steroid has been well known to have diabetogenic effect and mainly responsible for glucose intolerance after transplantation. Deflazacort, a new steroid, has been introduced as a substitute of conventional steroid to prevent glucose intolerance after transplantation. We performed prospective study of deflazacort conversion from conventional steroid in kidney transplant patients with pre-transplantation diabetes mellitus(pre-Tx DM) or PTDM. A total of 82 kidney transplant patients was included for this study. Forty two patients were converted to deflazacort as a conversion group and 40 patients were remained on conventional steroid as a control group. In conversion group, the patients were converted from steroid to deflazacort with ratio of 5:6 in dosage. Nine patients developed severe anorexia with nausea/vomiting and three patients among them went back on steroid within 3 months after conversion(conversion failure 7.1%). After minimal 6 months of follow-up, there was neither episodes of graft dysfunction nor rejection. There was a significant improvement of glucose control in conversion group. In 12 patients(30.8%), more than 50% dose reduction of insulin or oral hypoglycemics requirement was possible. In control group, however, only 2 patients showed greater than 50% of insulin or oral hypoglycemics dose reduction. We could find that deflazacort conversion had a significant impact on blood sugar control in PTDM patients(11/26) but not in pre-Tx DM patients(1/13). In conclusion, conversion to deflazacort in PTDM patients with stable graft function was safe and blood sugar control was readily possible without an increment of risks of rejection and infection. We propose to use deflazacort as a substitute for prednisone in PTDM patients with stable graft function.
Anorexia
;
Blood Glucose
;
Cyclosporine
;
Diabetes Mellitus
;
Follow-Up Studies
;
Glucose
;
Glucose Intolerance
;
Humans
;
Hypoglycemic Agents
;
Insulin
;
Kidney*
;
Prednisone*
;
Prospective Studies
;
Transplants