Two cases of malignant histiocytosis, in which skin involvement was a prominent finding at initial clinical presentation, are reported. 1nteresting histopathologic findings, including Langerhans granule in one case and numerous eosinophils in another, were observed. In one case remission was achieved with BACOP chemotherapy (Bleomycin, Adriamycin, Cyclophosphamide, Vincristine, and Prednisone). In the other case, the patient died nine months after the onset of the disease without any treatment.
Cyclophosphamide ; Doxorubicin ; Drug Therapy ; Eosinophils ; Histiocytic Sarcoma* ; Humans ; Skin ; Vincristine

No abstract available.
Leg*

In order to compare the corneal sensation after phacoemulsification and the planned extracapsular cataract extraction(p-ECCE), we studied 40 eyes of 31 patients prospetively. A Cochet-Bonnet esthesiometer was used to measure corneal sensitivity preoperatively and at one day, three day, one week, one month, and two months postoperatively, by the same surgeon using the same technique. There was no difference in corneal sensation between phacoemulsification and p-ECCE group preoperatively. The mean corneal sensitivity at 10:00(2:00) o`clock in phacoemulsificantion/p-ECCE was 17.3+/-7.0(18.2+/-6.7)/9.9+/-1.5(10.3+1.9), 22.1+/-6.9 (23.2+/-6.3)/14.1+/-2.3(14.3+/-2.3), 29.4+/-7.7(30.6+/-7.2)/17.7+2.2(18.7+/-2.2), 37.7+/-9.3(37.8+/-9.4)/26.3+/-7.9(27.7+/-8.4), 56.3+/-7.6(56.3+7.9)/59.2+/-3.8(59.4+/-2.7)mm after 1, 3, 7, 30, 60 days, respectively. Corneal sensation at the center and the 3, 6, and 9 o`clock positions was not changed in all eyes. Corenal sensitivity was significantly more recovered in phacoemulsification group than the p-ECCE group at postoperative onemonth(p<0.05). However, there were no statistically significant difference in recovery of corneal sensation between phacoemulsification group and p-ECCE group at postoperative two months. Conclusively corneal sensation returned to peroperative level at two months postoperatively in both groups.
Cataract Extraction* ; Cataract* ; Humans ; Phacoemulsification* ; Sensation*

The aims of this paper are to identify where the quality research activity has been and is carried out in Korea, and to examine weather the Korean plastic surgeons have sufficient capacity to place their official journal "The Journal of Korean Society of Plastic and Reconstructive Surgeons(KPRS)" to international databases. We investigated the publication productivity of all departments of plastic surgery in Korean medical colleges, hospitals, and clinics as measured by the number of papers in journals indexed in SCI(Science citation index). The 27 year period from 1974 to 2000 is covered. A total of 195 papers is published in SCI journals by the plastic surgeons in Korea. The first SCI paper was published in 1985; the number of publication has gradually increased. Since 1998, over 30 papers are annually published in SCI journals by Korean plastic surgeons. The production of SCI papers are concentrated in a few universities. About seventy percent of SCI journal papers is published by top seven medical schools; 25.6% by Yonsei university. In 1985, only one medical school was involved in the production of SCI journal papers. After 1997, however, more than 10 medical school and some surgeons in local clinics published SCI journal papers. The percent of SCI journal papers among all papers written by the Korean plastic surgeons increased recently: About 15% are published in SCI journals in 1999 and 2000 respectively. These data suggest that Korean plastic surgeons have enough capacity to place their official journal KPRS into international data bases.
Efficiency* ; Korea ; Publications* ; Schools, Medical ; Surgery, Plastic ; Weather

The ethmoid mucocele, resulting in the proptosis, is known a rare benign lesion. There are a number of ophthalmic manifestations of cystic lesion arising from the ethmoid sinus, which has destroyed the lamina papyracea and invaded the orbit. It is demonstrated by simple orbit X-ray and orbit CT scan. We experienced a case of a ethmoid mucocele in a 36-year-old man. which was associated with frontalgia, proptosis and transient intraocular pressure elevation and was improved after intranasal ethmoidectomy.
Adult ; Ethmoid Sinus* ; Exophthalmos ; Humans ; Intraocular Pressure* ; Mucocele* ; Orbit ; Tomography, X-Ray Computed

No abstract available.
Choledochal Cyst*

We injected tPA into the anterior chamber of 43 pesudophakic eyes with moderate to severe fibrinous membrane which had developed following cataract surgery from January, 1990 to August, 1990 at St. Mary's hospital. The results were as follows: 1. Intraocular tPA injection was resulted in complete fibrinolysis within 1 hour in 38 of 43 eyes and patial fibrinolysis in 5 of 43. 2. No corneal endothelial cell loss was found, and tPA did not appear to cause a significant rise in intraocular pressure. 3. Complications of tPA injection included mild, transient, periocular pain(3 eyes), anterior chamber fibrin debris(2 eyes) and anterior chamber hemorrhage(1 eye). The results indicated that tPA is dramatically effective for the clearance of fibrinous membrane after cataract surgery.
Anterior Chamber ; Cataract* ; Corneal Endothelial Cell Loss ; Fibrin* ; Fibrinolysis ; Intraocular Pressure ; Membranes* ; Tissue Plasminogen Activator*

PURPOSE: To report a case of corneal ulcer caused by Leclercia adecarboxylata in an immunocompetent patient. CASE SUMMARY: A previously healthy 43-year-old female presented with right ocular pain and was referred to our clinic under the impression of corneal abrasion and secondary infection. The patient was treated at a local clinic for 3 days using artificial tears, therapeutic contact lens, topical antibiotics, and anti-inflammatory eye drops but showed no improvement. Gram staining, bacterial and fungal cultures and antibiotic sensitivity test were performed from a corneal scrape. The cultures revealed growth of Leclercia adecarboxylata. The patient was treated with moxifloxacin and ofloxacin eye drops. After 2 weeks of treatment, the infection resolved without remaining scars. CONCLUSIONS: Reportedly, Leclercia adecarboxylata affects humans only as an opportunistic pathogen or part of polymicrobial infections. However, in the present case, Leclercia adecarboxylata was isolated as a single pathogen in an immunocompetent patient which is the first clinical report of this microorganism found in an ocular sample. Therefore, if antibiotic-susceptible gram-negative bacilli are found in opthalmologic samples, the above bacteria should be considerd in the diagnosis.
Adult ; Anti-Bacterial Agents ; Bacteria ; Cicatrix ; Coinfection ; Corneal Ulcer* ; Diagnosis ; Enterobacteriaceae* ; Female ; Humans ; Ofloxacin ; Ophthalmic Solutions

PURPOSE: To report three cases in which herpes simplex keratitis developed after initiation of latanoprost. METHODS: We experienced three patients with herpes simplex keratitis after latanoprost instillation, two patients with open angle glaucoma and one is congenital glaucoma. We preformed herpes simplex virus culture for two cases. RESULTS: One patient with history of herpes simplex keratitis, resolution when latanoprost was stopped; antiviral therapy could not eradicate herpes simplex keratitis until latanoprost was discontinued. The second patient with latanoprost associated herpes simplex keratitis cleared with discontinuation of latanoprost and start of antiviral therapy. The third patient had resolution, only when latanoprost was stopped. The result of viral cultures for two cases was negative. CONCLUSIONS: Clinicians should be aware of development or recurrence of herpes simplex keratitis when laranoprost is used for intraocular pressure control.
Glaucoma ; Glaucoma, Open-Angle ; Herpes Simplex* ; Humans ; Intraocular Pressure ; Keratitis, Herpetic* ; Recurrence ; Simplexvirus

PURPOSE: Suppression of the relatively high signal intensity of fat leads to more efficient use of thedynamic range for display of tissue contrast. In order to evaluate meniscal tears, we compared a fat-suppressedturbo spin-echo(FSTSE) sequence with turbo SE(TSE). MATERIALS AND METHODS: One hundred and seven knees in 103consecutive patients referred for MR study of the knee were imaged using both FSTSE and TSE sequence. The turbo SEsequence provided proton density-weighted and T2-weighted images (dual echo technique) with an effectiveecho-train length of five. For fat-suppression, a frequency-selective chemical presaturation pulse was applied.Forty-two knees (84 menisci) were studied arthroscopically and the findings were taken as the reference standard.FSTSE and TSE images were reviewed retrospectively by two radiologists. Next, for each patient, the quality ofFSTSE and TSE images was compared;the former were scored by each reviewer as either superior to, equal to, orinferior to TSE images. RESULTS: Among the 214 menisci evaluated, the results of FSTSE and TSE imaging were verysimilar (kappa index 0.87). Twenty four tears were found during arthroscopy in 84 menisci. FSTSE imaging was moresensitive than TSE (96% versus 83%), though specificity was equal(98%). Among the 107 cases, FSTSE images wererated by both observers as superior to TSE images for overall quality and visualization of the meniscus itself.CONCLUSION: For the evaluation of meniscal tears, FSTSE sequences were more sensitive than those obtained withTSE, and their image quality was superior. For the study of meniscus tears among a large population, FSTSE istherefore more useful than TSE.
Arthroscopy ; Humans ; Knee ; Magnetic Resonance Imaging* ; Protons ; Retrospective Studies ; Sensitivity and Specificity