Urticaria pigmentosa is a manifestation of mastocytosis characterized by persistent pigmented cutaneous lesions of various size that tend to urticate upon mechanical or chemical irritation, The disease is most common in ehildren and skin lesions after appear within 1 or 2 months of birth. Urticaria pigmentosa in children begins with disseminated eruption (buIlou type) or with a solitary tumor or nodule(solitary type). One case. of solitary type and one case of bullous type are reported in this paper. The one case is a solitary type of urticaria pigmentosa in 1 1/2 years old male who had dark brownish pigmented nodule(2.5 1cm) on right hack since 1 year ago. Tie other is a bullous type of urticaria pigmentousa in 6 months old male who had generalizcd. bulla, hemorragic bulla with crust & millium since 4 months ago. Dignosis was confirmed by histologic findings in which showed infiltration of mast cells in upper nr entire dermis arui rnetachromatic granules in mast cell on toluidine blue stain. Literature were reviewed briefly.
Child ; Dermis ; Humans ; Infant ; Male ; Mast Cells ; Mastocytosis ; Parturition ; Skin ; Tolonium Chloride ; Urticaria Pigmentosa* ; Urticaria*

Epidermolysis bullosa dystrophica is a rare, chronic non-infIammatory mechanobullous disease of hereditsry trait, which easily produces bulla by minor injury or spontaneously. Bullae usually developed first at birth or in infancy, involving especially hands, feet, knees, elbows and other pressure sites, which heal with atrophic and hypertrophic scars, loss of hair and nails, digital fusion, flexural contractures of the knee, elbow and wrist joints. A 5-year-old boy has had various sized recurrent buIlae on hands, feet, kneces and elbows, healed with atrophy of skin, miliums, deformities of toe and finger nails. Diagnosis was confirmed by clinical features and electronmicroscopic findings. Literature were reviewed briefly.
Atrophy ; Child, Preschool ; Cicatrix, Hypertrophic ; Congenital Abnormalities ; Contracture ; Diagnosis ; Elbow ; Epidermolysis Bullosa Dystrophica* ; Epidermolysis Bullosa* ; Fingers ; Foot ; Hair ; Hand ; Humans ; Knee ; Male ; Parturition ; Skin ; Toes ; Wrist Joint

Aplasia cutis congenita is an anomaly characterized by absence of localized areas of the integument. The most common type of aplasia cutis congenita is a circular or oval, sharply outlined ulcer 1 to 3cm in diameter on the vertex of the scalp at the level of the posterior fontanel. Two cases of aplasia cutis congenita are presented. The first case was in a male newborn infant with a localized defect on his scalp. The second case was also in a male newborn infant who had extensive symmetrical involvement of his heels. No similar conditions and associating other congenital anomalies were found in the family members of reported cases.
Cranial Fontanelles ; Ectodermal Dysplasia* ; Heel ; Humans ; Infant, Newborn ; Male ; Scalp ; Ulcer

Porokeratosis is a familial, chronic, progressive disorder which demonstrates a characteristic clinical and histologic picture. Since Mibelli described three cases in 1893, several clinical variants have been identified, all of which are delineated by a diagnostic histopathologic pattern. We reported a case of atypical linear porokeratosis that had three types of skin lesions. One was the plaque type, as originally described by Mibelli. And others were atypical lesions, as papules and verrucoid hyperkeratotic plaques.
Porokeratosis ; Skin

We observed the clinical and histopathologic characteristics of acquired, bilateral nevus of Ota-like macules in each 80 and 23 patients. The results were as follows: 1. All patients were female and the peak age of onset was third decade with an a,verage age of 27.4 years. 2. The colors of lesions were slate, brown, dark brown, and blue black in order of freguency. 3. The lesions were most comrnonly observed in the malar area and alae nasi. 4. Three patients had family history of acquired, bilateral nevus of Ota-like :macules. 5. Histopathologically pigment-bearing cells, bipolar or irregular in shape, were found mostly in the upper- and mid-portion of the dermis. The melanocytes showed weakly positive dopa reaction. 6. In electron microscopic observation, these pigrnent-bearing cells contained many singly dispersed melanosomes in stage 3 and 4 of melanization and wece surrounded by an extracellular sheath.
Age of Onset ; Dermis ; Dihydroxyphenylalanine ; Female ; Humans ; Melanocytes ; Melanosomes ; Nevus of Ota* ; Nevus*

Linear porokeratosis is a rare variant of porokeratosis and usually occurs in childhood. A 37-year-old female is presented with linear porokeratosis on the posterior aspeet of the right lower extremity exhibiting the classical histopathologic criteria of the disease. Treatment with an oral etretinate resulted in a remission of the lesions.
Acitretin ; Adult ; Etretinate ; Female ; Humans ; Lower Extremity ; Porokeratosis*

Purpura fulminans (gangrenosa) is a rare clinical syndrome characterized by sudden appearance of rapidly progressive symmetrical subcutaneous ecchymosis durimg the convalescent stage of various infectious disease. A 4 year-old. boy has developed multiple skin defects with necrosis on extrernities and gangrenous changes on the left foot following a meningococcemia. B-K amputation on left leg and. free skin graft for multiple skin defect on extremities were, carried out.
Amputation ; Child, Preschool ; Communicable Diseases ; Ecchymosis ; Extremities ; Foot ; Humans ; Leg ; Male ; Necrosis ; Purpura Fulminans* ; Purpura* ; Skin ; Transplants

Hepatitis B virus is of growing clinical importance. This virus not only produces acute and chronic liver disease but also produces a variety of dermatologic syndromes. A 77-year-old man with erythematous urticarial-like papulonodules had a chronic active hepatitis. And microscopic findings were compatible with allergic vasculitis. We reported a case of allergic vasculitis associated with chronic active hepatitis and reviewed literatures briefly.
Aged ; Hepatitis B virus ; Hepatitis, Chronic* ; Humans ; Liver Diseases ; Vasculitis*

She describe herein two cases of eccrine spiradenoma. One is an indolent and the other is painful or tender multiple small nodules distributed in a zosteriform pattern. Histopathologically, the encapsulated lobules of the tumor are composed of two types of cells, intensely staining cells and pale staining cells, usually arranged in whorls, cords, and pseudoglands. In the second case, enzyme histochemical staining and electron microscopic examination have been done and are compared with other cases in the literature.

A 33-year-old man had multiple, dome shaped, pin-head sized, hard papules on the center of face and pigeon's egg sized hard tumors on the left upper arm and the trunk. The histopathological findings of the skin biopsy specimens from face and left upper arm showed tumor islands composed of basophilic cells of the same sppearance as basalioma cells, arranged in a lacelike and solid aggregates, without horn cysts.
Adult ; Animals ; Arm ; Basophils ; Biopsy ; Horns ; Humans ; Islands ; Ovum ; Skin