1.Operation methods according to the location of intrahepatic duct stones.
Il Gyue PARK ; Jae Hong KIM ; Ju Sup PARK
Journal of the Korean Surgical Society 1993;45(5):654-662
No abstract available.
2.Bladder dysfunction after radical abdominal hysterectomy.
Chang Il PARK ; Jae Hyung SA ; Tchan Kyu PARK
Journal of the Korean Academy of Rehabilitation Medicine 1993;17(4):493-498
No abstract available.
Hysterectomy*
;
Urinary Bladder*
3.Idiopathic type I mesangiocapillary glomerulonephritis in children.
Jae Hong PARK ; Il Soo HA ; Yong CHOI
Korean Journal of Nephrology 1992;11(4):441-449
No abstract available.
Child*
;
Glomerulonephritis, Membranoproliferative*
;
Humans
4.Mechanisms of HPV-16-induced Transformation in Human Epithelial Cells in Culture.
Heon Soo LEE ; Jae Ho YANG ; Il Soo PARK
Korean Journal of Gynecologic Oncology and Colposcopy 1996;7(4):298-307
Human epithelial cell line immortalized by Ad12-SV40 hybrid virus was transfected with plasmid containing HPV-16 via calcium-phosphate method. Subsequently, 8 clonal cell lines were obtained after G418 selection. Among these clonal cells, clonal cell-4(C-4) and clonal cell-6(G-6) showed increases of tumorigenic cellular properties such as saturation density, soft agar colony formation and cell aggregation. Morphological alteration such as appearane of foci was observed on these two clones after passage 6 and 7(50 to 55 days after transfection). When clonal cells and control cells were treated with MNNG(0.01ug/ml), both C-4 and C-6 showed increases of tumorigenic cellular properties and the level of increase was much more elevated as compared to clonal cells prior to MNNG treatment. Appearance of foci formation was observed in C-4 and C-6 after passage-6. After passage-8, control cells and all clonal cells showed morphological alterations. It seems that treatment of cells containing HPV-16 DNA with MNNG increases tumorigenic properties of the cells and expedite morphological transformations. (continue)
Agar
;
Cell Aggregation
;
Cell Line
;
Clone Cells
;
DNA
;
Epithelial Cells*
;
Human papillomavirus 16
;
Humans*
;
Methylnitronitrosoguanidine
;
Plasmids
5.Response and Toxicity of Chemotherapy in 78Cases of Malignant Ovarian Tumors.
Jae yeon WON ; Il Soo PARK ; Soon Gu HWANG
Korean Journal of Gynecologic Oncology and Colposcopy 1996;7(2):127-134
For evaluation of the response and toxicity of the combination chemotherapy, forty six patients with malignant ovarian tumors who had prior surgery were treated with combination chemotherapy from January 1985 to March 1991 at the Department of Obstetrics and Gynecology, Kyung-pook National University Hospital. The results were as follows : 1. The responses were in complete 20 cases(43.5%), in partial 9 cases(19,6%), in stable 6 cases(13.0%), in progressive 11 cases(23.9%) among 46 patients. 2. By the response rates of various combination chemotherapy regimens, the response rate of CAP was 64%(16/25), CP 57.1%(8/14), VAC 100%(3/3), VBP 50%(1/2), FAM 0%(0/1), and Melphalan 100%(1/1) respectively. 3. As the chemotoxicities of combination chemotherapy, leukopenia 20 cases(46.5%), thrombocytopenia 2 cases(4.7%), anemia 20 cases(46.5%), nephrotoxity 6 cases(14.6%), hepatotoxicity 7 cases(18.4%) were observed.
Anemia
;
Drug Therapy*
;
Drug Therapy, Combination
;
Gynecology
;
Humans
;
Leukopenia
;
Melphalan
;
Obstetrics
;
Thrombocytopenia
6.Binding of B Cell - Derived Autocrine Growth Factor to Hemoglobin.
Jae Seung PARK ; Il Whan CHOI ; Young Mi SHIN
Korean Journal of Immunology 1998;20(1):25-30
Normal human B cells produce autocrine growth factor in response to Staphylococcus aureus Cowan I strain (SAC). However, the functional role and molecular nature of the B cell derived-B cell growth factor (B-BCGF) are largely unknown. We have tried to investigate the nature of B-BCGF using mAb for several years. We report here that B- BCGF is capable of binding to hemoglobin (Hb). The concentrated culture supernatant from tonsillar B cells stimulated with SAC for 24 h was loaded into the fast protein liquid chromatography and ion-exchange chromatography. The peak with BCGF activity was shown to have a M.W. of 16-18 Kda in polyacrylamide gel electrophoresis followed by silver stain. Amino acid sequence of the fraction was found to identical to human hemoglobin (Hb) by more than 85%. However, Hb itself had no BCGF activity. The presence of Hb in culture supernatant was due to the contamination of SRBC during B cell purification. SRSC were completely removed from B cells by percoll-gradient centrifugation and B cells were stimulated with SAC and exogenous Hb was added to the cultures. The Hb fraction from FPLC again showed a BCGF activity. These data strongly suggested that BCGF binds to Hb. We confirmed this in dot blot as well as Western blot. The M.W of Hb-binding BCGF was 20 Kda. This information may provide a rapid progress in research of BCGF.
Amino Acid Sequence
;
B-Lymphocytes
;
Blotting, Western
;
Centrifugation
;
Chromatography, Ion Exchange
;
Chromatography, Liquid
;
Electrophoresis, Polyacrylamide Gel
;
Humans
;
Silver
;
Staphylococcus aureus
7.Comparison of Erectile Response to Intracavernous Injection Therapy in Diabetic and Non-diabetic Erectile Dysfunction Patients.
Ok Roung JANG ; Jae Il KIM ; Seok San PARK
Korean Journal of Urology 2000;41(3):425-429
No abstract available.
Erectile Dysfunction*
;
Humans
;
Male
8.Clinical analysis of the bactibilia.
Seong Jae CHA ; Jung Hyo LEE ; Sung Il PARK
Journal of the Korean Surgical Society 1993;45(1):73-82
No abstract available.
9.A procedure for delayed gastric emptying on pyloric preserving pancreaticoduodenectomy.
Tae Il JIN ; Jae Hong KIM ; Ju Sup PARK
Journal of the Korean Surgical Society 1993;45(5):588-695
No abstract available.
Gastric Emptying*
;
Pancreaticoduodenectomy*
10.A procedure for delayed gastric emptying on pyloric preserving pancreaticoduodenectomy.
Tae Il JIN ; Jae Hong KIM ; Ju Sup PARK
Journal of the Korean Surgical Society 1993;45(5):588-695
No abstract available.
Gastric Emptying*
;
Pancreaticoduodenectomy*