Acral persistent papular mucinosis has been thought to be a distinct for of cutaneous mucinosis not associated with systemic diseases. It was recently classified as one of five subtypes of localized lichen mixedematosus. A 64-year-old man presented with a 15-year history of flesh-colored to translucent papules and a few round hypopigmented patches on his wrists, back of the hands, and distal forearms. Biopsy from the papular lesions revealed focal mucin accumulation in the upper reticular dermis. The clinical and histopathological features were consistent with acral persistent papular mucinosis.
Biopsy ; Dermis ; Forearm ; Hand ; Humans ; Lichens ; Middle Aged ; Mucinoses ; Mucins ; Scleromyxedema* ; Wrist

No abstract available.
Herpes Zoster* ; Psoriasis*

No abstract available.
Dermatitis* ; Tacrolimus ; Tetracycline*

BACKGROUND: Totally implantable access port (TIAP) provides reliable, long term vascular access with minimal risk of infection and allows patients normal physical activity. With wide use of ports, new complications have been encountered. We analyzed TIAP related complications and evaluated the outcomes of two different percutaneous routes of access to superior vena cava. METHODS: All 172 patients who underwent port insertion with internal jugular approach (Group 1, n = 92) and subclavian approach (Group 2, n = 79) between August 2011 and May 2013 in a single center were analyzed, retrospectively. Medical records were analyzed to compare the outcomes and the occurrence of port related complications between two different percutaneous routes of access to superior vena cava. RESULTS: Median follow-up for TIAP was 278 days (range, 1-1868). Twenty four complications were occurred (14.0%), including pneumothorax (n = 1, 0.6%), migration/malposition (n = 4, 2.3%), pinch-off syndrome (n = 4, 2.3%), malfunction (n = 2, 1.1%), infection (n = 8, 4.7%), and venous thrombosis (n = 5, 2.9%). The overall incidence was 8.7% and 20.3% in each group (p = 0.030). Mechanical complications except infectious and thrombotic complications were more often occurred in group 2 (p = 0.033). The mechanical complication free probability is significantly higher in group 1 (p = 0.040). CONCLUSIONS: We suggest that the jugular access should be chosen in patients who need long term catheterization because of high incidence of mechanical complication, such as pinch-off syndrome.
Catheterization ; Catheters ; Follow-Up Studies ; Humans ; Incidence ; Jugular Veins ; Medical Records ; Motor Activity ; Pneumothorax ; Retrospective Studies ; Subclavian Vein ; Vascular Access Devices ; Vena Cava, Superior ; Venous Thrombosis

We found an error in this article. The author's affiliation.

Eccrine angiomatous hamartoma is a rare benign tumor similar to hemangioma in appearance. Unlike hemangioma, it has numerous eccrine structures in addition to numerous capillary channels. Occasionally it accompanies hyperhidrosis and pain. The sweat apparatuses in the lesions showed antigenic activities by immunohistochemical stains, particularly with anti-S100 protein and anti-CEA, the two common antigens associated with eccrine sweat glands. The antigenic activities of anti-S100 protein and anti-CEA in sweat gland structure of 2 presenting cases, one with sweating and the other without sweating, were compared to each other. As a result, we found no differences between the two cases. Although an aggressive treatment is not required due to its benign nature, total excision can be considered in cases with severe symptoms. We present two cases of eccrine angiomatous hamartoma developed on right knee joint areas in a 2-year-old male and a 10 month-old male, respectively.
Capillaries ; Child, Preschool ; Coloring Agents ; Hamartoma* ; Hemangioma ; Humans ; Hyperhidrosis ; Infant ; Knee Joint ; Male ; Sweat ; Sweat Glands ; Sweating

This study was designed to evaluated the effects of opioid receptor agonists on the spontaneous alternation behaviour in an animal model of obsessive-compulsive disorder in rats. According to the theory that dopamine is related to the biological etiology of obsessive-compulsive disorder, the effect of the nalbuphine(opioid kappa agonist) and the tramadol(opioid mu agonist), which act as manipulating agents on the inhibition or stimulation of dopamine release, in the spontaneous alternation behaviour were evaluated. 24 hours prior to the experiment, rats were food-deprived. These rats were put into the T-maze, in which white and black goal boxes were baited with small amounts of chocolate milk. Each rat was given 2 set of 7 trials during which it was placed in the start box and allowed to choose the one of the goal boxes for each time. After identifying the stable baseline of spontaneous alternation behaviour, nonselective 5-HT agonist 5-MeODMT(1.25mg/kg/IP) disrupted spontaneous alternation. Rats were stratified into fluoxetine(10mg/kg/IP), nalbuphine(10mg/kg/IP), tramadol(46.4mg/kg/IP), and saline(0.5cc/IP) injection group with experimental drug treatment for 21 days. The effects on the 5-M?DMT(1.25mg/kg/IP) induced disruption of spontaneous alternation behaviour were checked at the next day of discontinuation of drug treatment. The results were as follows : 1) At the day after 21 days of the drug treatment, the nalbuphine treated group and the fluoxetine treated group showed significant difference from the tramadol treated group and the saline treated group in the 5-MeODMT(1.25mg/kg/IP) induced suppression of spontaneous alternation behaviour. 2) Within each drug treatment group, the fluoxetine treated group showed significant difference between before and after the treatment of fluoxetine in the 5-MeODMT(1.25mg/kg/IP) induced suppression of spontaneous alternation behaviour. And also, the nalbuphine treated group showed significant difference between before and after the treatment of nalbuphine in the 5-MeODMT(1.25mg/kg/IP) induced suppression of spontaneous alternation behaviour. There was no difference between the baseline and after the treatment of nalbuphine in the 5-MeODMT(1.25mg/kg/IP) induced suppression of spontaneous alternation behaviour. We indentified that the opioid kappa agonist that act as dopamine release inhibitor affect the spontaneous alternation behaviour which is an animal model of obsessive-compulsive disorder in rat.
Animals ; Cacao ; Dopamine ; Fluoxetine ; Milk ; Models, Animal ; Nalbuphine ; Obsessive-Compulsive Disorder ; Rats* ; Receptors, Opioid ; Serotonin Receptor Agonists ; Tramadol

No abstract available.
Humans ; Organophosphate Poisoning* ; Respiratory Insufficiency*

A 66-year-old man with incidentally detected mass in the left kidney visited our hospital. Intravenous pyelogram, ultrasonogram, computerized tomography suggested a renal cell carcinoma in the left side of the horseshoe kidney. A left radical nephrectomy with division of the isthmus was performed. The pathological diagnosis revealed renal cell carcinoma consisting of clear cell type without invasion of the capsule or renal pelvis.
Aged ; Carcinoma, Renal Cell* ; Diagnosis ; Humans ; Kidney Pelvis ; Kidney* ; Nephrectomy ; Ultrasonography

Basal cell carcinoma(BCC) exists in great variety. Adamantinoid BCC is one of the rare types of BCC. Histologically, the tumor masses are surrounded by a layer of cells in which the nuclei tend to palisade. Inside this layer, the tumor masses consist of cells with elongated nuclei and stellate cytoplasm stretched as thin, connection bridges across empty spaces, producing adamantinoid appearance. We report a case of adamantinoid BCC in a 49 year-old woman who had a single, asymptomatic, dusky erythematous to black colored nodule on her right jaw area.
Carcinoma, Basal Cell* ; Cytoplasm ; Female ; Humans ; Jaw ; Middle Aged