1.Therapeutic effects of resperidone in the treatment of chronic schizophrenia.
Soon Won PARK ; Hae Ik CHUNG ; Byung Jo KANG
Journal of Korean Neuropsychiatric Association 1993;32(5):744-757
No abstract available.
Schizophrenia*
2.An experimental study on radiation hepatitis
Ik Won KANG ; Charn Il PARK ; Chu Wan KIM
Journal of the Korean Radiological Society 1981;17(2):187-192
The effect of radiation on the liver should be of unusual interest in as much as there are two highly specialized kinds of epithelium besides an important endothelial system and vascular and fibrous elements tocompare, But there are several difficulites in the way of knowledge of the sensitivity and reaction of the liverto radiation. Perhaps the most important is the regenerative abillity of the liver cells. It has been assumed that the liver as an organ is relatively resistant to radiation injury. Yet there are reports of necrosis of the liverin man resulting from doses of radiation which have not caused a skin reaction or any demonstrable effect on the stomach. The author made an experiment to elucidate more clearly the changes in resum enezymes and histopathology of rat's liver following irradiation to the liver with a single dose of 2,000 rads. The resuls obtained are asfollows; 1. Serum SGOT activities were significatnly elevated, 1 and 2 weeks after irradiation, and normalized after 4 weeks. 2. Serum SGPT activities were significantly elevated 2 weeks after irradiation, and normalized after4 weeks. 3. Alakline phosphatase activity were significantly elevated 1, 2 and 4 weeks after irradiation, and normalized after 8 weeks. 4. Histopathologic changes were focal necrosis, inflammatory cell infiltration, loss of intra cytoplasmic glycogen particles, and vacuolar degenerations of hepatocytes. It appeared marked 2 weeks after irradiation, restored after 4 weeks, and normalized after 8 weeks.
Alanine Transaminase
;
Aspartate Aminotransferases
;
Cytoplasm
;
Epithelium
;
Glycogen
;
Hepatitis
;
Hepatocytes
;
Liver
;
Necrosis
;
Radiation Injuries
;
Skin
;
Stomach
3.Treatment of Distal Femoral Fractures with a Retrograde Supracondylar Intramedullary Nail assisted with Arthroscopy.
Byoung Hyun MIN ; Shin Kang CHO ; Won Ik LEE ; Chung Su YU ; Shin Young KANG
The Journal of the Korean Orthopaedic Association 1998;33(7):1838-1845
Since Green et al has introduced a new technique of retrograde intramedullary nail, the use of retrograde interlocking intramedullary nails has been recommended as one of the treatment options for the distal femoral fracture. However there are some disadvantages that an arthrotomy is required for insertion and the knee joint could often be violated. Authors present a simple, arthroscopically assisted method using the retrograde intramedullary nailing for distal femoral fractures with minimal invasiveness to the knee. From March 1995 to March 1997, the retrograde intramedullary nail was used to treat 9 distal femoral fractures. Five of 9 patients were fractured at the distal shaft of the femur and others were fractured at the supracondylar region of the femur. Only one of the fractures was open injury(Gustilo-Anderson grade II). Significant concomitant knee joint injuries were revealed through the arthroscopy in 3 patients. Eight of 9 fractures healed by 5 months, but one fracture was not healed and required bone grafting. Average knee range of motion was 130. Complications included 1 nonunion and 1 hardware failure. There were no patellofemoral problems and no posttraumatic arthritis of the knee joint. This arthroscope-assisted method have some potential benefits that include decreased risk of damage to the knee joint, early evaluation and treatment of the associated knee joint injuries, and accurate placement of the nail.
Arthritis
;
Arthroscopy*
;
Bone Transplantation
;
Femoral Fractures*
;
Femur
;
Fracture Fixation, Intramedullary
;
Humans
;
Knee
;
Knee Joint
;
Range of Motion, Articular
4.A Case of Sebaceous Hyperplasia with Linear Arrangement.
Sang Hyun CHO ; Ik Jun KO ; Baik Kee CHO ; Won HOUH ; Kang Woo LEE
Korean Journal of Dermatology 1989;27(4):452-455
We report a case of sebaceous hyperplasia showing linear arrangement in a 13-year-old girl. The lesion was found at birth and became prominent gradually. Multiple small discrete yellowish papules were arranged in a linear pattern on the temporal srea of the face. Unusual, incidental histopathologic finding was a sebaceous lobule lying in a dilated infundibular portion, which appeared to represent transfollicular extrusion of sebaceous lobule as a natural phenomenon.
Adolescent
;
Deception
;
Female
;
Humans
;
Hyperplasia*
;
Parturition
5.A Case of Neurofibromatosis.
In Kyung SUNG ; Sung Won KANG ; Ik Jun LEE ; Sung Hoon CHO
Journal of the Korean Pediatric Society 1983;26(1):97-101
No abstract available.
Neurofibromatoses*
6.Persistent Candidemia in Major Burn Patients: Radiologic Findings of the Thorax.
Eil Seong LEE ; Kwan Seop LEE ; Ik Won KANG
Journal of the Korean Radiological Society 1997;36(4):601-605
PURPOSE: To describe radiologic findings of burn-associated persistent candidemia of the thorax. MATERIALS AND METHODS: This study included 42 patients with major burns in whom blood culture had shown the presence for more than 24 hours of persistent candidemia. The duration of positive culture for candidiasis ranged from two to 67 days(mean, 15 days). Radiographic(n=42) and thin-section CT findings(n=13) were retrospectively analyzed. The onset, pattern, size, distribution and persistence of parenchymal abnormalities as well as the presence or absence of pleural effusions, mediastinal lymphadenopathy and cardiomegaly were assessed. RESULTS: On chest radiographs, positive findings were noticed in 61.9%(26/42) and on thin-section CT, in 76.9%(10/13). The most frequent radiographic finding was pulmonary nodule(s), observed in 14 patients(33.3%). in 13, these were bilateral. Bronchovascular bundle thickening(n=6, 14.3%), consolidation(n=4, 9.5%), cardiomegaly(n=6, 14.3%) and pleural effusion(n=4, 9.5%) were also observed. Those lesions appeared eight to 129 days(mean, 33days) after the burn. Radiographic abnormalities persisted for seven to 115 (mean, 35) days, regardless of the treatment. Thin-section CT showed parenchymal abnormalities in 10/13 patients(76.9%) and subpleural nodules of less than 1cm in diameter and without halo in all patients. Cardiomegaly, pleural effusion and mediastinal adenopathy were observed on CT in 5(38.5%), 4(30.8%) and 2(15.4%) of the 13 patients, respectively. CONCLUSION: In a high proportion of patients with burn-associated candidemia, chest radiograph and thin-section CT findings were positive. The most frequent radiographic parenchymal abnormality was multiple bilateral nodules.
Burns*
;
Candidemia*
;
Candidiasis
;
Cardiomegaly
;
Humans
;
Lymphatic Diseases
;
Pleural Effusion
;
Radiography, Thoracic
;
Retrospective Studies
;
Thorax*
7.Effect of Pancuronium into the Lateral Ventricle on the Repiratory and Circulatory Functions in Rabbit.
Korean Journal of Anesthesiology 1984;17(1):1-5
In this study the action of pancuronium given directly into the lateral ventricle on the mean blood pressure, heart rate, respiratory frequency and skeletal muscular contractility of the rabbit were investigated. Pancuronium, which a dose of 10ug/kg and 30kg/kg were given into the lateral ventricle of rabbit. 1) Intraventricular injection of 10ug/kg of pancuronium increased pulse rate, respiratory frequency and muscle contraction and the differences were not statiscally significant. 2) Intraventricular injection of 30ug/kg of pancuronium produced a gradual increase of respiratory frequency which began at 5 minutes after drug injection and continued over a half hour. The difference between control and experimental value was statistically significant (p<0.005) while pulse rate and muscular contractility were increased but not significant. 3) Mean blood pressure was not changed after intraventricular injection of the pancuronium.
Blood Pressure
;
Heart Rate
;
Injections, Intraventricular
;
Lateral Ventricles*
;
Muscle Contraction
;
Pancuronium*
8.Computed tomography of the thorax
Ik Won KANG ; Kee Hyun CHANG ; Jae Hyung PARK ; Man Chung HAN
Journal of the Korean Radiological Society 1982;18(4):703-709
CT provides a valuable new perspective in assessing abnormalities of the thorax. In patients with amediastinal mass or widening detected by plain chest radiography, a definite diagnosis is sometimes possible whichwould not obtainable by conventional radiological technique. Clinical staging of bronchogenic carcinoma can beachieved by CT better than any other radiologic method. In fifty patients with histologically or angiographically confirmed disease of the thorax,an analysis of chest radiography and chest CT manifestations was made, and theresults were as follows; 1. 27 patients with mediastinal mass detected by chest radiography, a definite diagnosiswas possible in 10 patients (36%), who were 6 with teratodermoid, 1 with thymic cyst, 3 with aneurysm. In allpatients, the extent and localization of mediastinal mass could be established more precisely than by the chestradiography. 2. In 15 patients wtih bronchogenic carcinoma, 9 patients (60%) showed hilar adenopathy ormediastinal adenopathy which could not be noted on the chest radiography. 3. Main CT findings of braonchogeniccarcinoma were peripheral lung mass, spiculated or lobulated margin, adhesion to pleura or chest wall, andatelectasis or chronic pneumonia. 4. Commonly observed CT findings of teratodermoid were well capsulated mass,calcification, fat density , and multi-loculation. 5. Commonly observed CT findings of thymoma were homogenousmass, round contour, partially preserved mediastinal fat. CT was superior in evaluation of mediastinum and in the detemination of the extent of known bronchogenic carcinoma.
Aneurysm
;
Carcinoma, Bronchogenic
;
Diagnosis
;
Humans
;
Lung
;
Mediastinal Cyst
;
Mediastinum
;
Methods
;
Pleura
;
Pneumonia
;
Radiography
;
Thoracic Wall
;
Thorax
;
Thymoma
;
Tomography, X-Ray Computed
9.An experimental study on the effect of intraoperative irradiation on the healing of anastomosed small intestine
Heung Suk SEO ; Ik Won KANG ; Sung Whan HA ; Man Chung HAN
Journal of the Korean Radiological Society 1983;19(1):15-22
To evaluate the influence of intraoperative irradiation on the healing of jejunal anastomosis, an experimentalstudy was undertaken using a total of 150 rats. The bursting pressure of the normal jejunum was obtained in groupI. Group II was subjected to resection and anastomosis, and group III was irradiated on the anastomosed jejunumwith a single dose of 1,000 rads. Healing process was evaluated by measuring bursting pressure of the anastomosedjejunum on each postoperative day from 2nd to 14th, and on 21 th day. Bursting pressure was tested by inflatingthe loop of gut with water, and bursting sites were observed. The resuls obtained are summarized as follows; 1.The bursting pressure of the anastomosed jejunum retained normal strength by the 7th postoperative day in thenonirradiated group, whereas by the 11th postoperative day in the irradiated group. 2. Irradiation caused delay inthe healing of anastomosis of the jejunum until the 10th postoperative day; but after then, there was nosignificant difference in bursting pressure between both groups. 3. In the jejunal segments with normal strength,bursting occurred exclusively at the non-anastomotic site in both groups; Bursting started along the mesentericborder in the non-irradiated group, whereas rupture usually occurred on the antimesenteric border in theirradiated group. in the jejunal segments with subnormal strength, bursting usually started on the mesentericborder of the anastomotic site in both groups. The results indicate that intraoperative irradiation with a singledose of 1,000 rads causes no harmful effect on the healing of anastomosis of the jejunum in rats. Therefore, thisstudy suggests the possibility of more effective clinical application of intraoperative irradiation.
Animals
;
Intestine, Small
;
Jejunum
;
Rats
;
Rupture
;
Water
10.Ultrasonographic ejection fraction of normal gallbladder
Jin Hun PARK ; Seung Yup KIM ; Yaung Hee PARK ; Ik Won KANG ; Jong Sup YOON
Journal of the Korean Radiological Society 1984;20(2):301-304
Real-time ultrasongraphy is a simple, accurate, noninvasive and potentially valuable means of studying gallbladder size and emptying. The authors calculated ultrasonographically the ejection fraction of 80 cases of normally functioning gallbladder on oral cholecystography, from June 1983 to April 1984, at the department of radiology, Hangang Sacred Heart Hospital. The results were obtained as follows; 1. Ultrasongraphic Ejection Fraction at 30 minutes after the fatty meal was 73.1+-16.85. 2. There was no significant difference in age and sex, statistically.
Cholecystography
;
Gallbladder
;
Heart
;
Meals