No abstract available.
Schizophrenia*

The effect of radiation on the liver should be of unusual interest in as much as there are two highly specialized kinds of epithelium besides an important endothelial system and vascular and fibrous elements tocompare, But there are several difficulites in the way of knowledge of the sensitivity and reaction of the liverto radiation. Perhaps the most important is the regenerative abillity of the liver cells. It has been assumed that the liver as an organ is relatively resistant to radiation injury. Yet there are reports of necrosis of the liverin man resulting from doses of radiation which have not caused a skin reaction or any demonstrable effect on the stomach. The author made an experiment to elucidate more clearly the changes in resum enezymes and histopathology of rat's liver following irradiation to the liver with a single dose of 2,000 rads. The resuls obtained are asfollows; 1. Serum SGOT activities were significatnly elevated, 1 and 2 weeks after irradiation, and normalized after 4 weeks. 2. Serum SGPT activities were significantly elevated 2 weeks after irradiation, and normalized after4 weeks. 3. Alakline phosphatase activity were significantly elevated 1, 2 and 4 weeks after irradiation, and normalized after 8 weeks. 4. Histopathologic changes were focal necrosis, inflammatory cell infiltration, loss of intra cytoplasmic glycogen particles, and vacuolar degenerations of hepatocytes. It appeared marked 2 weeks after irradiation, restored after 4 weeks, and normalized after 8 weeks.
Alanine Transaminase ; Aspartate Aminotransferases ; Cytoplasm ; Epithelium ; Glycogen ; Hepatitis ; Hepatocytes ; Liver ; Necrosis ; Radiation Injuries ; Skin ; Stomach

Since Green et al has introduced a new technique of retrograde intramedullary nail, the use of retrograde interlocking intramedullary nails has been recommended as one of the treatment options for the distal femoral fracture. However there are some disadvantages that an arthrotomy is required for insertion and the knee joint could often be violated. Authors present a simple, arthroscopically assisted method using the retrograde intramedullary nailing for distal femoral fractures with minimal invasiveness to the knee. From March 1995 to March 1997, the retrograde intramedullary nail was used to treat 9 distal femoral fractures. Five of 9 patients were fractured at the distal shaft of the femur and others were fractured at the supracondylar region of the femur. Only one of the fractures was open injury(Gustilo-Anderson grade II). Significant concomitant knee joint injuries were revealed through the arthroscopy in 3 patients. Eight of 9 fractures healed by 5 months, but one fracture was not healed and required bone grafting. Average knee range of motion was 130. Complications included 1 nonunion and 1 hardware failure. There were no patellofemoral problems and no posttraumatic arthritis of the knee joint. This arthroscope-assisted method have some potential benefits that include decreased risk of damage to the knee joint, early evaluation and treatment of the associated knee joint injuries, and accurate placement of the nail.
Arthritis ; Arthroscopy* ; Bone Transplantation ; Femoral Fractures* ; Femur ; Fracture Fixation, Intramedullary ; Humans ; Knee ; Knee Joint ; Range of Motion, Articular

PURPOSE: To describe radiologic findings of burn-associated persistent candidemia of the thorax. MATERIALS AND METHODS: This study included 42 patients with major burns in whom blood culture had shown the presence for more than 24 hours of persistent candidemia. The duration of positive culture for candidiasis ranged from two to 67 days(mean, 15 days). Radiographic(n=42) and thin-section CT findings(n=13) were retrospectively analyzed. The onset, pattern, size, distribution and persistence of parenchymal abnormalities as well as the presence or absence of pleural effusions, mediastinal lymphadenopathy and cardiomegaly were assessed. RESULTS: On chest radiographs, positive findings were noticed in 61.9%(26/42) and on thin-section CT, in 76.9%(10/13). The most frequent radiographic finding was pulmonary nodule(s), observed in 14 patients(33.3%). in 13, these were bilateral. Bronchovascular bundle thickening(n=6, 14.3%), consolidation(n=4, 9.5%), cardiomegaly(n=6, 14.3%) and pleural effusion(n=4, 9.5%) were also observed. Those lesions appeared eight to 129 days(mean, 33days) after the burn. Radiographic abnormalities persisted for seven to 115 (mean, 35) days, regardless of the treatment. Thin-section CT showed parenchymal abnormalities in 10/13 patients(76.9%) and subpleural nodules of less than 1cm in diameter and without halo in all patients. Cardiomegaly, pleural effusion and mediastinal adenopathy were observed on CT in 5(38.5%), 4(30.8%) and 2(15.4%) of the 13 patients, respectively. CONCLUSION: In a high proportion of patients with burn-associated candidemia, chest radiograph and thin-section CT findings were positive. The most frequent radiographic parenchymal abnormality was multiple bilateral nodules.
Burns* ; Candidemia* ; Candidiasis ; Cardiomegaly ; Humans ; Lymphatic Diseases ; Pleural Effusion ; Radiography, Thoracic ; Retrospective Studies ; Thorax*

We report a case of sebaceous hyperplasia showing linear arrangement in a 13-year-old girl. The lesion was found at birth and became prominent gradually. Multiple small discrete yellowish papules were arranged in a linear pattern on the temporal srea of the face. Unusual, incidental histopathologic finding was a sebaceous lobule lying in a dilated infundibular portion, which appeared to represent transfollicular extrusion of sebaceous lobule as a natural phenomenon.
Adolescent ; Deception ; Female ; Humans ; Hyperplasia* ; Parturition

No abstract available.
Neurofibromatoses*

In this study the action of pancuronium given directly into the lateral ventricle on the mean blood pressure, heart rate, respiratory frequency and skeletal muscular contractility of the rabbit were investigated. Pancuronium, which a dose of 10ug/kg and 30kg/kg were given into the lateral ventricle of rabbit. 1) Intraventricular injection of 10ug/kg of pancuronium increased pulse rate, respiratory frequency and muscle contraction and the differences were not statiscally significant. 2) Intraventricular injection of 30ug/kg of pancuronium produced a gradual increase of respiratory frequency which began at 5 minutes after drug injection and continued over a half hour. The difference between control and experimental value was statistically significant (p<0.005) while pulse rate and muscular contractility were increased but not significant. 3) Mean blood pressure was not changed after intraventricular injection of the pancuronium.
Blood Pressure ; Heart Rate ; Injections, Intraventricular ; Lateral Ventricles* ; Muscle Contraction ; Pancuronium*

The purpose of this paper is to define the bacterial sources of wound infection after surgery including debridement for open fractures. Total number of patients were 123 during surgery July 1975 to Oct. 1976 at Hangang Sacred Heart Hospital. Out of 123 cases 17 were infected postoperatively. Serial bacterial cultures were performed for specimens taken from the contaminated wound in emergency room and by exposing the Petri-dishes in the operating room. Additional cultures were carried out for 17 specimens taken from the infected wounds postoperatively. Positive bacterial cultures from the initial wounds were obtained in 71 cases (57.7%) out of 123 contaminated wounds in emergency room. Setting monitoring of air contamination in conventional operating room, 51 colonies of bacterial growth per 1 hour exposure were noted and common organisms were colliform bacilli, streptococci and staphylococci in order. Postoperative wound infection rate was 13. 8%. Common pathogens were staphylococcus aureus, coliform bacilli and pseudomonas and kanamycin was most effective antibiotics. The retrospective bacteriological studies for 17 infected cases elucidated following results: 1) Organisms of same species; from initial wound and infected wound postoperatively 7 cases 2) Organisms of same species; from air contamination in the operating room and infectected wound postoperatiyely 5 cases 3) Organism of same species; from air contamination in the operating room, initial wound and infected wound postoperatively 1 case 4) Others (contagious or endogenous origin) 4 cases The results reveal that the initial contaminated open fracture and air contamination during surgery are the main sources of postoperative infection. Four cases which the infectious sources were not determined included in contagious origin dogmaticaIly.
Anti-Bacterial Agents ; Debridement ; Emergency Service, Hospital ; Enterobacteriaceae ; Fractures, Open ; Heart ; Humans ; Kanamycin ; Operating Rooms ; Pseudomonas ; Retrospective Studies ; Staphylococcus aureus ; Surgical Wound Infection ; Wound Infection ; Wounds and Injuries

Delayed diagnosis of the compartmental syndrome and subsequent delay in performing the fasciotomy can result in needless loss of function and possible amputation of the involved extremity. Unfortunately early evidence of this syndrome is difficult to assess. A direct measurement of the tissue pressure within a closed compartment has been developed which provides physicians with reliable information for determining the need for fasciotomy. In the 27 cases of the tibia fracture, tissue pressure was measured directly by method of the needle manometer in the Department of Orthopedic Surgery, Han Kang Sung Sim Hospital from March, 1979 to August, 1979. The results were as follows: 1. The highest mean tissue pressure per hour was 28 mmHg in anterior compartment at 24 hours after trauma, and 28.4 mmHg in deep post compartment at the same hours. 2. The highest pressure measured in all cases was 38 mmHg in anterior compartment at 24 hours and 39 mmHg in deep posterior compartment at 48 hours after trauma. 3. The return of increased tissue pressure to less than 10 mmHg took 122.6 hours in anterior and 124.4 hours in deep posterior compartment. 4. Tissue pressre was higher when there was associated fibula fracture. 5. Tissue pressure was higher in displaced fractures than in undisplaced fractures. 6. Tissue pressure was higher when fracture was in its upper one-third. 7. Tissue pressure was higher in comminuted fracture than simple fracture.
Amputation ; Delayed Diagnosis ; Extremities ; Fibula ; Fractures, Comminuted ; Methods ; Needles ; Orthopedics ; Tibia

CT provides a valuable new perspective in assessing abnormalities of the thorax. In patients with amediastinal mass or widening detected by plain chest radiography, a definite diagnosis is sometimes possible whichwould not obtainable by conventional radiological technique. Clinical staging of bronchogenic carcinoma can beachieved by CT better than any other radiologic method. In fifty patients with histologically or angiographically confirmed disease of the thorax,an analysis of chest radiography and chest CT manifestations was made, and theresults were as follows; 1. 27 patients with mediastinal mass detected by chest radiography, a definite diagnosiswas possible in 10 patients (36%), who were 6 with teratodermoid, 1 with thymic cyst, 3 with aneurysm. In allpatients, the extent and localization of mediastinal mass could be established more precisely than by the chestradiography. 2. In 15 patients wtih bronchogenic carcinoma, 9 patients (60%) showed hilar adenopathy ormediastinal adenopathy which could not be noted on the chest radiography. 3. Main CT findings of braonchogeniccarcinoma were peripheral lung mass, spiculated or lobulated margin, adhesion to pleura or chest wall, andatelectasis or chronic pneumonia. 4. Commonly observed CT findings of teratodermoid were well capsulated mass,calcification, fat density , and multi-loculation. 5. Commonly observed CT findings of thymoma were homogenousmass, round contour, partially preserved mediastinal fat. CT was superior in evaluation of mediastinum and in the detemination of the extent of known bronchogenic carcinoma.
Aneurysm ; Carcinoma, Bronchogenic ; Diagnosis ; Humans ; Lung ; Mediastinal Cyst ; Mediastinum ; Methods ; Pleura ; Pneumonia ; Radiography ; Thoracic Wall ; Thorax ; Thymoma ; Tomography, X-Ray Computed