A clinical study was made on 28 patients (31 lesions) with urinary tract obstruction using
Arm ; Hospitals, General ; Humans ; Radionuclide Imaging* ; Renal Circulation ; Ureter ; Urinary Tract*

A clinical study was made on 52 patients (55 organs) with renal injuries in Capital Armed Forces General Hospital during the period from January, 1980 to May, 1982. Emphasis was placed on comparison of the expectant and early surgical management. Following results were obtained: 1. The nonpenetrating injuries were 45 cases (86.5%), penetrating, 7 cases (13.5%) and the most common cause of nonpenetrating injuries was traffic accident in 23 cases (44.2%) and the most common cause of penetrating injuries was gunshot in 6 cases (11.6%). 2. As to the management of nonpenetrating injuries, the expectant management was performed in 32 cases (71.1%) and early surgical management in 13 cases (28.9%). 3. All cases of penetrating injuries were managed with early surgical intervention. 4. As to the early surgical management in nonpenetrating injuries, nephrectomy was performed in 6 cases (46.2%), simple closure in 6 cases (46.2%) and partial nephrectomy in I case. 5. As to the early surgical management in penetrating injuries, nephrectomy was performed in 5 cases (71.4%), simple closure in 1 case and partial nephrectomy in I case. 6. In group of expectant management, gross hematuria disappeared at 2.7 days on an average. 7. In nonpenetrating injuries, complication were 6 cases (18.8%) after expectant management, while none, after early surgical management. 8. In penetrating injuries, complication were 2 cases (28.6%) after early surgical management. 9 As to the management of complication in nonpenetrating injuries, nephrectomy was performed in 4 cases (66.7%), deroofing of cyst in 1 case and expectant management in 1 case. 10. As to the management of complication in penetrating injuries, incision and drainage was performed in 1 case and colostomy in 1 case.
Accidents, Traffic ; Arm ; Colostomy ; Drainage ; Hematuria ; Hospitals, General ; Humans ; Nephrectomy ; Wounds, Nonpenetrating

No abstract available.
Ligaments*

OBJECTIVE: Symptom provocation paradigms using event-related functional magnetic resonance imaging(fMRI) can be an important tool to visualize neuroanatomic correlates of PTSD symptoms. The purpose of this study is to measure regional changes of brain upon exposure to fear stimulus and elucidate the probable relation between signal changes and fear response in PTSD. METHOD: Event-related fMRI was performed during a task where traffic accident-related photos and checkerboards were presented in 9 women with PTSD and 9 woman normal controls in unpredictable order. MRI data were acquired on a 1.5 T GE vision system with a head volume coil. Stimuli were presented on a mirror mounted on the head coil. A total of 200 functional images were taken during a 10-minute scanning session. TR was 3 seconds and inter-stimulus time was varing 4.5 to 11.5 seconds. Data was analyzed using SPM99. RESULTS: In PTSD group, the fear conditions versus the neutral conditions showed activations in both occipital cortex, both fusiform gyrus, left parietal lobule, both insula, right cerebellar tonsil, right putamen, right claustrum, but deactivations in both prefrontal gyrus(p<0.001). In normal control group, activation were found for the fear conditions as compared with the neutral conditions in left fusiform gyrus, both occipital cortex, left parietal lobule, right frontal lobule(p<0.001). CONCLUSIONS: Emotion provocation paradigm using event-related functional magnetic resonance imaging can be applied to illustrate fear response mechanism in PTSD. The result suggests that insula, limbic lobe, cerebellum may play a role in mediating fear response in PTSD.
Basal Ganglia ; Brain ; Cerebellum ; Female ; Head ; Humans ; Magnetic Resonance Imaging* ; Negotiating ; Palatine Tonsil ; Putamen ; Rabeprazole ; Stress Disorders, Post-Traumatic*

A total of 30 cases of cerebral gliomas, including 6 cases of low grade astrocytomas, 6 anaplasticastrocytoomas and l8 glioblastomas multiforme, was examined immunohistochemically to demonstrate the overexpression of mutant forms of p53 protein and to evaluate their relationships with histological subtypes. A p53 monoclonal antibody was applied to the routine formalin fixed, paraffin-embedded tissues for this study using microwave-assisted avidin-biotin method. Overexpression of p53 protein was identified in 4 out of 6 anaplastic astrocytomas (66.7%) and in l3 out of l8 glioblastomas multiforme (72.2%). No immunohistochemical positivity of p53 was found in adjacent normal brain tissue, gliosis and 6 cases of astrocytoma. These results suggest that overexpression of mutant p53 may be an important step in the development and progression of malignant astrocytoma, especially of the aggressive subtypes of glioma, including glioblastoma multiforme.
Humans

Teratoma of the testis is a type of mixed tumor made up of various kinds of tissue representing the three primitive layers of blastoderm. Recently we experienced two cases of testicular teratoma in 23-year-old male patients, so we report these two cases of testicular teratoma with review of literatures.
Blastoderm ; Humans ; Male ; Teratoma* ; Testis ; Young Adult

We have experienced a rare case of progressive supranuclear palsy with hallucination and delusion. The common manifestations of progressive supranuclear palsy are gait disturbance, mental change and sign of vertical ophthamoplegia but no efficacious therapy has been known. Neuropsychiatric symptom clusters include cognitive impairment, affective and behavioral changes, sleep disturbance, and psychotic symptoms. Though schizophrenia-like psychosis has been reported but this is certainly rare. Addressing a case of progressive supranuclear palsy, in whom parkisonian symptoms appeared with concurrent psychotic symptoms, we emphasize accurate diagnosis.
Delusions ; Diagnosis ; Gait ; Hallucinations ; Psychotic Disorders ; Supranuclear Palsy, Progressive*

No abstract available.
Adult* ; Forearm* ; Humans

OBJECTIVE: To investigate the changes of shoulder proprioception in normal subjects, according to the direction of the evoked fatigue on the shoulder muscle group. METHOD: 20 healthy volunteers (14 males and 6 females, age 20~35 years) with entirely normal shoulders participated in this study. Before fatigue exercises, the proprioception tests were performed during active reposition (ARP) and passive reposition (PRP) of dominant shoulder, using isokinetic dynamometer, System 3 Pro (Biodex medical system, New York, USA). Three trials each of active and passive repositioning (2degrees/sec) were recorded. We also estimated the results of the peak torque shoulder movements. The subjects performed maximal efforts with five repetitions on the direction of flexion, abduction, internal rotation and external rotation. The mean values of maximal concentric voluntary contraction (MVC: peak torque of each muscle group contraction) were recorded. We repeated fatigue exercises until the peak torque dropped to 30% three times consistently, then retested the proprioception of shoulder joints. We compared the proprioceptive changes of the shoulder with pre-fatigue test and post-fatigue test on the direction of shoulder movements. RESULTS: There were significant differences of shoulder proprioception between pre-fatigue test and post-fatigue test of ARP in shoulder abduction and external rotation (p<0.05). CONCLUSION: In our study, the proprioception of shoulder joint decreased more prominently on external rotation and abduction movements under severely provoked muscle fatigue around the shoulder joint.
Contracts ; Exercise ; Fatigue ; Female ; Humans ; Male ; Muscle Fatigue ; Muscles ; New York ; Proprioception ; Shoulder ; Shoulder Joint ; Torque

Digital therapeutics (DTx) are emerging as a transformative innovation in healthcare offering evidence-based digital interventions for the treatment, management, and prevention of various diseases and disorders. In Korea, DTx have gained significant attention as potential solutions to the increasing burden of chronic diseases and mental health conditions. However, the Korean DTx market faces several challenges that hinder its widespread adoption and integration into the national healthcare system. This study provides a comprehensive analysis of the current state of the DTx market in Korea, identifies the key challenges impeding its growth, and proposes strategies for overcoming these obstacles. This study utilized a literature review and market analysis approach to examine the latest research, industry reports, and regulatory documents related to DTx. The analysis focused on three primary areas: (1) the current regulatory landscape, (2) technological advancements and challenges, and (3) economic and commercial factors influencing DTx adoption in Korea. A comparative analysis of global regulatory practices was also conducted to identify best practices. The findings revealed that while Korea has made significant strides in supporting DTx development, the market remains in its early stages. The key challenges include underdeveloped regulatory frameworks, issues with data quality and security, and a lack of established reimbursement pathways. We recommend developing tailored regulatory frameworks for DTx, enhancing policy support for small and medium-sized enterprises involved in DTx development, and increasing investments in technological infrastructure. By addressing these challenges, Korea could position itself as a leader in the global DTx market, delivering innovative and effective treatments to enhance patient care and outcomes.