Fibrous histiocytoma are complex group of tumors that feature cells resembling fibroblasts and histiocytes.In a case of fibrous histiocytoma involving the cornea and corneolimbus, we evaluated the finding of H-E, Masson-trichrome, reticulin, CD68, alpha-1-antitrypsin antibody and smooth muscle actin antibody stain after the localized excision in 26 years old male patient. In H-E stain, tumor cell included many multinucleated giant cells having abundant eosinophilic and foamy cytoplasm infiltreated by numerous lymphocyte, CD68 & alpha-1-antit-rypsin antibody staining resulted in diffuusely positive finding. Therefore examination. Good result was noted after complete excision at 6 month follow-up.
Actins ; Adult ; Cornea* ; Cytoplasm ; Eosinophils ; Fibroblasts ; Follow-Up Studies ; Giant Cells ; Histiocytoma, Benign Fibrous* ; Humans ; Lymphocytes ; Male ; Muscle, Smooth ; Reticulin

Fluorescein angiography has become an indispensable ophthalmic diagnostic tool for detecting retinal and optic nerve pathology. The oral angiography is safer than intravenous angiography and is practical when intravenous administration is difficult. Since the resolution is somewhat inferior to that of intravenous fluorescein angiography, the use of oral fluorescein angiography was limited to the observation of dye leakage and pooling in late phase. We analyzed the sequence of fundus fluorescence following oral administration of the fluorescein dye in 34 subjects. Serial fundus photographs were taken at interval of 30 to 60 seconds for the first 15 minutes, and for the remaining 60 minutes, at interval of 5 to 15 minutes. Optic disc appeared first(6.6 minutes) followed by major vessels on and adjacent to the disc(7.4 minutes), choroidal fluorescence(9.0 minutes) and all the fundus structures(9.8 minutes). The peak fluorescence was detected about 25 minutes after dye ingestion. Sufficient fluorescence was obtained in all the cases without major complications and in the phase of maximal fluorescence, all the fundus structures were clearly visualized. In conclusion, oral fluorescein angiography can be a possible alternative to intravenous fluorescein angiography in whom, intravenous injection is unsuitable.
Administration, Intravenous ; Administration, Oral ; Angiography ; Choroid ; Eating ; Fluorescein Angiography* ; Fluorescein* ; Fluorescence ; Injections, Intravenous ; Optic Nerve ; Pathology ; Retinaldehyde

PURPOSE: We investigated whether Tc-99m MIBI imaging is useful to predict the response of drug treatment in patients with rheumatoid arthritis. MATERIALS AND METHODS: 24 patients (15 women and 9 men, age 49 +/- 12 year) rheumatoid arthritis and treated with disease modifying antirheumatic drugs (DMARDs) were included in this study. Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) were measured, and Tc-99m MIBI scan was obtained before drug treatment. Quantitative analysis of uptake in diseased joints was performed and expressed as joint-to background ratio (J/B) and percent retention (%R) of Tc-99m MIBI. Clinical symptoms were evaluated and graded from 0 (no) to 3 (severe) regarding to presence of tenderness and swelling. RESULTS: J/B of the diseased joints were significantly correlated with ESR and CRP (p< 0.05). A highly significant correlation was found between the improvement of clinical symptoms and %R of Tc-99m MIBI (p< 0.05). CONCLUSION: The results demonstrate that Tc-99m MIBI scan may be used to predict the therapeutic response in patients with rheumatoid arthritis.
Antirheumatic Agents ; Arthritis, Rheumatoid* ; Blood Sedimentation ; C-Reactive Protein ; Female ; Humans ; Joints ; Male

Colorectal cancer is the third most common cancer in Korea and the third leading cause of death from cancer. Treatment outcomes for colon cancer are steadily improving due to national health screening programs with advances in diagnostic methods, surgical techniques, and therapeutic agents.. The Korea Colon Cancer Multidisciplinary (KCCM) Committee intends to provide professionals who treat colon cancer with the most up-to-date, evidence-based practice guidelines to improve outcomes and help them make decisions that reflect their patients’ values and preferences. These guidelines have been established by consensus reached by the KCCM Guideline Committee based on a systematic literature review and evidence synthesis and by considering the national health insurance system in real clinical practice settings. Each recommendation is presented with a recommendation strength and level of evidence based on the consensus of the committee.