1.Massive Empyema Associated With Transient Hypogammaglobulinemia of Infancy and IgA Deficiency.
Kuhn PARK ; Kyung Yil LEE ; Mi Hee LEE ; Joon Sung LEE ; Ji Chang KIM
Journal of Korean Medical Science 2009;24(2):357-359
Transient hypogammaglobulinemia of infancy (THI) is originally defined as a physiological maturation defect of immunoglobulin G (IgG) production that occurs at 3-6 months of age and lasts until 18 to 36 months of age. We report here on a 22-month-old child with THI and IgA deficiency, who had massive pneumococcal empyema. Her depressed IgG level returned to normal within 6 months, but IgA level was still low at 6 yr of age. Although THI is an age-dependent and self-limiting disorder, severe infection that includes an atypical presentation of an infection may occur in some patients and this requires evaluation with immunologic study.
Agammaglobulinemia/complications/*diagnosis/immunology
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Anti-Bacterial Agents/therapeutic use
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Ceftriaxone/therapeutic use
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Drug Resistance, Bacterial
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Empyema, Pleural/*diagnosis/etiology/radiography
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Female
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Humans
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IgA Deficiency/*diagnosis/immunology
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Immunoglobulin A/blood
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Immunoglobulin G/blood
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Infant
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Staphylococcal Infections/*diagnosis/drug therapy/microbiology
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Tomography, X-Ray Computed