Size selection of the laryngeal mask airway (LMA) Classic based on actual body weight remains a common practice. However, ideal body weight might allow for a better size selection in obese patients. The purpose of our study was to compare the utility of ideal body weight and actual body weight when choosing the appropriate size of the LMA Classic by a randomized clinical trial. One hundred patients with age 20 to 70 yr, body mass index > or =25 kg/m2, and the difference between LMA sizes based on actual weight and ideal weight were allocated to insert the LMA Classic using either actual body weight or ideal body weight in a weight-based formula for size selection. After insertion of the device, several variables including insertion parameters, sealing function, fiberoptic imaging, and complications were investigated. The insertion success rate at the first attempt was lower in the actual weight group (82%) than in the ideal weight group (96%), even it did not show significant difference. The ideal weight group had significantly shorter insertion time and easier placement. However, fiberoptic views were significantly better in the actual weight group. Intraoperative complications, sore throat in the recovery room, and dysphonia at postoperative 24 hr occurred significantly less often in the ideal weight group than in the actual weight group. It is suggested that the ideal body weight may be beneficial to the size selection of the LMA Classic in overweight patients (Clinical Trial Registry, NCT 01843270).
Adult ; Aged ; *Body Weight ; Equipment Design ; Female ; Human Engineering/*methods ; Humans ; Ideal Body Weight/*physiology ; Laryngeal Masks/*classification ; Male ; Middle Aged ; Overweight/*physiopathology ; Prosthesis Fitting/*methods ; Reproducibility of Results ; Republic of Korea ; Sensitivity and Specificity ; Young Adult

Anorexia nervosa, bulimia and other related eating disorders are a heterogenous group of psychiatric disorders whose prevalence rates reach 0.5-1.0% for anorexia nervosa and 1.0-3.0% for bulinmia nervosa. Anorexia nervosa is characterized by a refusal to maintain a minimally normal body weight and bulimia is characterized by repeated episodes of binge eating, misuse of laxatives. diuretics or other medications ; fasting and excessive exercise. A disturbance in perception of body shape and weight is an essential feature of both disorders. Patients with eating disorders may have numerous medical, hypothalamic endocrine, metabolic and nutritional abnormalities. There have been several conceptual models to explain the etiology of eating disorders These are socio-cultural, family pathological, individual psychodynamic, developmental psychobiologiccl, primary hypothalamic dysfunctional, cognitive-behavioral and affective disorder theories. Among these thoeries, this paper attempts to review the biological theory and pharmacotherapy in eating disorders. Specifically, this review deals with physiology of eating behavior, neurotransmitter regulation of appetite and eating bvehavior, disturbances in brcin neurotransmitter system, neuroendocrine findings in anorexia nervosa and bulimia nervosa. and finally pharmacotherapy. Based on this review, future directions for research are also sutggested.
Anorexia Nervosa ; Appetite ; Biology* ; Bulimia ; Bulimia Nervosa ; Disulfiram ; Diuretics ; Drug Therapy* ; Feeding and Eating Disorders* ; Eating* ; Fasting ; Feeding Behavior ; Humans ; Ideal Body Weight ; Laxatives ; Mood Disorders ; Neurosecretory Systems ; Neurotransmitter Agents ; Physiology ; Prevalence