No abstract available.
Spondylolisthesis*

No abstract available.
Patellar Ligament*

BACKGROUND: The Pap smear has brought about a dramatic improvement in the prevention of cervical cancer in women worldwide. In an effort to decrease the occasional false negatives in the Pap smear and further increase the screened population, ThinPrep Pap Test (TP), a fluid-based cytology collection method, has been developed. With preservation of claimed advantages of TP, we have developed a Pap test solution for manual preparatory process and compared our manually processed fluid-based Pap smear with TP to identify cytologic similarities and differences between the two methods. METHODS: Cervical swipes of 204 patients were prospectively collected in the 'Pap solution' and also in PreservCyt solution for TP. Diagnoses and smear characteristics were compared. RESULTS: The diagnoses of the paired smears agreed in 190 of the 204 cases (93.1%). The smear characteristics regarding overall cellularity and background cellularities were similar in the two methods and the stainability of the cells was virtually the same. CONCLUSIONS: The 'Pap solution' has similar performance characteristics as TP in many aspects. With its advantages of cost-effectiveness and easier preparatory process, the 'Pap solution' can match previously implemented thin layer preparation.
Female ; Humans ; Prospective Studies ; Uterine Cervical Neoplasms

PURPOSE: The purpose of this study was to compare postoperative range of motion and functional outcomes among patients who received high-flexion total knee arthroplasty using cruciate-retaining (CR-Flex) and posterior-stabilized (PS-Flex) type prostheses. MATERIALS AND METHODS: Among 127 patients (186 knees) who underwent high-flexion total knee arthroplasty between 2005 and 2007, 92 knees were placed in the CR-Flex group, and 94 knees were placed in the PS-Flex group. After two years of postoperative follow-up, clinical and radiographic data were reviewed. Postoperative non-weight-bearing range of knee motion, angle of flexion contracture and functional outcomes based on the Western Ontario and McMaster Universities Osteoarthritis (WOMAC) functional sub-scale were assessed and compared between the two groups. RESULTS: After the 2-year postoperative period, the mean range of motion was 131degrees in the CR-Flex group and 133degrees in the PS-Flex group. There were no significant differences in postoperative range of motion between the two groups. Only age at operation and preoperative range of motion were significantly associated with postoperative range of motion after high-flexion total knee arthroplasty. Postoperative functional outcomes based on the WOMAC functional sub-scale were slightly better in the CR-Flex group (9.2+/-9.1 points) than in the PS-Flex group (11.9+/-9.6 points); however, this difference was not statistically significant (p=non-significant). CONCLUSION: The retention or substitution of the posterior cruciate ligament does not affect postoperative range of motion (ROM) or functional outcomes, according to 2 years of postoperative follow-up of high-flexion total knee arthroplasty.
Aged ; Arthroplasty, Replacement, Knee/*methods ; Female ; Humans ; Knee Prosthesis ; Middle Aged ; Posterior Cruciate Ligament/*surgery ; Postoperative Period ; Range of Motion, Articular/*physiology ; Recovery of Function/physiology ; Treatment Outcome

Potassium (K+) balance is achieved by the control of urinary K+ excretion and by the control of K+ absorption from the digestive tract. While it is well established that colonic H/K-ATPase a subunit mRNA is expressed in the kidney, distal colon, and uterus, little is known about the cellular localization and expression levels of this gene in chronic hypokalemia. Accordingly, Northern analysis and in situ hybridization (ISH) were carried out to analyze the expression of mRNA encoding the colonic H/K-ATPase a subunit in normal and potassium-restricted (2 weeks) rats. Northern analysis demonstrated that colonic H/K-ATPase a subunit mRNA was abundantly expressed in normal and potassium-restricted rat uterus. Abundance of colonic H/K-ATPase a subunit mRNA in potassium-restricted rat uterus was increased but, not statistically significant compared to that of controls. By ISH, mRNA for colonic H/K-ATPase a subunit was detected in the endometrial epithelial cells and the uterine glands. Both groups exhibited comparable cellular patterns of labeling, but signal intensity of potassium- restricted rats was higher than normal rats. The endometrial epithelial cells exhibited a mixture of hybridization signal intensity. Most cells had intense hybridization signal for colonic H/K-ATPase a subunit mRNA, some cells had moderate, and a few cells had weak. In summary, colonic H/K-ATPase a subunit mRNA is expressed in the endometrial epithelial cells and the uterine glands. These results suggest that two (or more) H/K-ATPase a subunit isoforms are present in rat uterus and this gene contributes to potassium reclamation during chronic hypokalemia to regulate the pH and/or electrolyte concentration of uterine fluid.
Absorption ; Animals ; Colon* ; Epithelial Cells ; Gastrointestinal Tract ; Hydrogen-Ion Concentration ; Hypokalemia* ; In Situ Hybridization ; Kidney ; Potassium ; Protein Isoforms ; Rats* ; RNA, Messenger* ; Uterus*

PURPOSE: This study aimed to evaluate the efficacy of simultaneous computed tomography (CT) and quantitative CT (QCT) in patients with osteoporotic hip fracture (OHF) by analyzing the osteoporosis detection rate and physician prescription rate in comparison with those of conventional dual-energy X-ray absorptiometry (DXA). MATERIALS AND METHODS: This study included consecutive patients older than 65 years who underwent internal fixation or hip arthroplasty for OHF between February and May 2015. The patients were assigned to either the QCT (47 patients) or DXA group (51 patients). The patients in the QCT group underwent QCT with hip CT, whereas those in the DXA group underwent DXA after surgery, before discharge, or in the outpatient clinic. In both groups, the patients received osteoporosis medication according to their QCT or DXA results. The osteoporosis evaluation rate and prescription rate were determined at discharge, postoperative (PO) day 2, PO day 6, and PO week 12 during an outpatient clinic visit. RESULTS: The osteoporosis evaluation rate at PO week 12 was 70.6% (36 of 51 patients) in the DXA group and 100% in the QCT group (P < 0.01). The prescription rates of osteoporosis medication at discharge were 70.2% and 29.4% (P < 0.001) and the cumulative prescription rates at PO week 12 were 87.2% and 60.8% (P=0.003) in the QCT and DXA groups, respectively. CONCLUSION: Simultaneous CT and QCT significantly increased the evaluation and prescription rates in patients with OHF and may enable appropriate and consistent prescription of osteoporosis medication, which may eventually lead to patients' medication compliance.
Absorptiometry, Photon ; Ambulatory Care Facilities ; Arthroplasty ; Hip Fractures ; Hip ; Humans ; Medication Adherence ; Osteoporosis ; Prescriptions

PURPOSE: Ischiofemoral impingement (IFI)-primarily diagnosed by magnetic resonance imaging (MRI)-is an easily overlooked disease due to its low incidence. The purpose of this study was to evaluate the usefulness of false profile view as a screening test for IFI. MATERIALS AND METHODS: Fifty-eight patients diagnosed with IFI between June 2013 and July 2017 were enrolled in this retrospective study. A control group (n=58) with matching propensity scores (age, gender, and body mass index) were also included. Ischiofemoral space (IFS) was measured as the shortest distance between the lateral cortex of the ischium and the medial cortex of lesser trochanter in weight bearing hip anteroposterior (AP) view and false profile view. MRI was used to measure IFS and quadratus femoris space (QFS). The receiver operating characteristics (ROC), area under the ROC curve (AUC) and cutoff point of the IFS were measured by false profile images, and the correlation between the IFS and QFS was analyzed using the MRI scans. RESULTS: In the false profile view and hip AP view, patients with IFI had significantly decreased IFS (P < 0.01). In the false profile view, ROC AUC (0.967) was higher than in the hip AP view (0.841). Cutoff value for differential diagnosis of IFI in the false profile view was 10.3 mm (sensitivity, 88.2%; specificity, 88.4%). IFS correlated with IFS (r=0.744) QFS (0.740) in MRI and IFS (0.621) in hip AP view (P < 0.01). CONCLUSION: IFS on false profile view can be used as a screening tool for potential IFI.
Area Under Curve ; Diagnosis, Differential ; Femur ; Hip ; Humans ; Incidence ; Ischium ; Magnetic Resonance Imaging ; Mass Screening ; Propensity Score ; Retrospective Studies ; ROC Curve ; Sensitivity and Specificity ; Weight-Bearing

PURPOSE: This study retrospectively reviewed the results of a closed reduction and internal fixation with cannulated screws for a displaced femoral neck fracture. MATERIALS AND METHODS: Among 631 patients between January 1991 and December 2000, 27 patients classified as Garden stage III or IV were treated with a closed reduction and internal fixation with cannulated screws. The mean follow-up duration was 4.5 years. The mean age of the patients was 56.5 years. RESULTS: Union and the restoration of function was observed in 15 cases (55.6%), and failure occurred in 12 cases (44.4%). The cause of failure was early stage reduction loss due to a failure to obtain anatomical reduction on the surgical field in 4 cases, reduction loss and displacement during the follow up period after an appropriate reduction at surgery in 4 cases and avascular necrosis in 4 cases. Seven cases were converted to a total hip arthroplasty, 4 cases were converted to bipolar hemiarthroplasty and 1 case is currently being followed up. CONCLUSION: A closed reduction and internal fixation for displaced femoral neck fracture showed a high failure rate. Therefore, an accurate anatomical reduction, firm internal fixation and efforts to prevent further unnecessary vascular injury will be needed to reduce the high failure rate and complications.
Arthroplasty, Replacement, Hip ; Femoral Neck Fractures* ; Femur Neck* ; Follow-Up Studies ; Hemiarthroplasty ; Humans ; Necrosis ; Retrospective Studies ; Vascular System Injuries

OBJECTIVE: To evaluate the correlation of the cross-sectional areas (CSA) of paraspinal (multifidus and erector spinae) and psoas muscles and chronic low back pain by MRI (magnetic resonance image) in young and middle-aged patients. METHOD: Medical records of eighty subjects (50 young-aged and 30 middle-aged men) with low back pain were retrospectively reviewed. Their MR images were scanned and analysed by means of pixel to find the lumbar paraspinal and psoas muscle CSA and evaluated the correlation of the types of disc and age. RESULTS: There were significant increases of body mass index (BMI) in middle-aged patients compared with young- aged, and no difference in the disc types. Paraspinal muscle atrophy was increased in young patients with HIVD (herniated intervertebral disc), but not in middle-aged patients although they had HIVD. CONCLUSION: The paraspinal and psoas muscle atrophy could be assessed by MRI of lumbar spine in young patient with chronic low back pain. It may helpful for further evaluation and planning the treatment of low back pain.
Atrophy ; Body Mass Index ; Humans ; Low Back Pain* ; Magnetic Resonance Imaging* ; Male ; Medical Records ; Muscles* ; Paraspinal Muscles ; Psoas Muscles ; Retrospective Studies ; Spine

No abstract available.
Glutathione* ; Oligodendroglia*