1.The Role of Lumbodorsal Fascotomy in the Treatment of Peratlytic Scoliosis and Pelvic Obliquity
Kwon Ick HA ; Keun Woo KIM ; Eun Yong LEE ; Duk Yong LEE ; Moon Sik HAHN
The Journal of the Korean Orthopaedic Association 1972;7(1):1-8
The authors carriod out lumbodorsal fasciotomy on six cases of paralytic scoliosis with pelvic obliquity. In our experience, in those older children and adolescents with paralysis in whom scoliotic curve is not severe and is more or less static, correction and maintenance of the correction can be achieved by lumbodorsal fasciotomy without resorting to spine fusion. While it is a common practice to leave a mild and static curve uncorrected, even a mild degree of scoliosis, when associated with pelvic obliquity, abduction contracture of the hip, instability of the other hip and leg length discrepancy, is a major problem in paralytic patients. Initial results indicate that lumbodorsal fasciotomy, combined with contralateral Soutters or Campbells fasciotomy if necessary, is a simple and effective method in correcting these deformities and restoring balance and function.
Adolescent
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Child
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Congenital Abnormalities
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Contracture
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Health Resorts
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Hip
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Humans
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Leg
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Methods
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Paralysis
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Scoliosis
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Spine
2.Safety and Immunogenicity Assessment of an Oral Cholera Vaccine through Phase I Clinical Trial in Korea.
Young Ok BAIK ; Seuk Keun CHOI ; Jae Woo KIM ; Jae Seung YANG ; Ick Young KIM ; Chan Wha KIM ; Jang Hee HONG
Journal of Korean Medical Science 2014;29(4):494-501
The safety, tolerability and immunogenicity of an oral cholera vaccine (OCV) was assessed in adult Korean male through an open-label, non-comparative clinical study. Two doses of vaccine with an interval of 2 weeks were given to 20 healthy subjects. A total of 7 adverse events occurred in 6 subjects. However, no clinically significant change was observed in electrocardiograms, vital signs, physical examinations, and clinical laboratory tests. The immunogenicity of OCV was evaluated by serum vibriocidal assay where anti-Vibrio cholerae O1 and O139 antibodies were measured at day 0, 14, and 28 of vaccine administration. The antibody titers ranged from < 2.5-5,120 for V. cholerae O1 Inaba, < 2.5-10,240 for V. cholerae O1 Ogawa and < 2.5-480 for V. cholerae O139. In addition, the fold increase in antibody titers ranged from 1-4,096 for O1 Inaba, 1-8,192 for O1 Ogawa, and 1-384 for O139. The seroconversion rate was 95% and 45% for O1 and O139 antibodies, respectively. Our study clearly shows that administration of two doses of OCV at a 2 week-interval increases an appropriate level of antibody titer in the serum of healthy Korean adult males (Clinical Trial Number, NCT01707537).
Administration, Oral
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Adult
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Antibodies, Bacterial/*blood/immunology
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Antibody Formation
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Cholera/*prevention & control
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Cholera Vaccines/adverse effects/*immunology
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Creatine Kinase/blood
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Humans
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Male
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Republic of Korea
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Toothache/etiology
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Vibrio cholerae O1/immunology
3.Erratum: Addition of Author's Affiliated Institute and Correction of the Author's Name. Corrected: Safety and Immunogenicity Assessment of an Oral Cholera Vaccine through Phase I Clinical Trial in Korea.
Yeong Ok BAIK ; Seuk Keun CHOI ; Jae Woo KIM ; Jae Seung YANG ; Ick Young KIM ; Chan Wha KIM ; Jang Hee HONG
Journal of Korean Medical Science 2014;29(8):1182-1182
We found errors in our published article.
4.Erratum: Addition of Author's Affiliated Institute and Correction of the Author's Name. Corrected: Safety and Immunogenicity Assessment of an Oral Cholera Vaccine through Phase I Clinical Trial in Korea.
Yeong Ok BAIK ; Seuk Keun CHOI ; Jae Woo KIM ; Jae Seung YANG ; Ick Young KIM ; Chan Wha KIM ; Jang Hee HONG
Journal of Korean Medical Science 2014;29(8):1182-1182
We found errors in our published article.
5.Left Paraduodenal Hernia Presenting with Atypical Symptoms.
Min Young YUN ; Yun Mi CHOI ; Sun Keun CHOI ; Sei Joong KIM ; Seung Ick AHN ; Kyung Rae KIM
Yonsei Medical Journal 2010;51(5):787-789
Paraduodenal hernias are a rare congenital malformation, but they are the most common internal hernias. They develop secondary to a failure in midgut rotation, which may lead to small bowel obstruction or other clinical manifestations. The authors recently experienced a case of a left paraduodenal hernia presenting with unusual symptoms of left flank pain and vomiting.
Adult
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Hernia/*complications/*diagnosis/pathology/surgery
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Humans
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Intestinal Obstruction/*etiology/surgery
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Male
6.The predictive value of serum myeloma protein in solitary plasmacytoma
Won Ick CHANG ; Hyeon Kang KOH ; Sung-Soo YOON ; Han-Soo KIM ; Keun-Yong EOM ; Il Han KIM
Radiation Oncology Journal 2020;38(2):129-137
Purpose:
To identify the clinical usefulness of serum M protein and to establish a rationale for regular follow-up with serum protein electrophoresis in solitary plasmacytoma.
Materials and Methods:
Sixty-nine patients with solitary plasmacytoma and solitary plasmacytoma with minimal marrow involvement according to the International Myeloma Working Group criteria were retrospectively reviewed.
Results:
At a median follow-up of 6.2 years, 5-year local control (LC), 5-year multiple myeloma-free survival (MMFS), 5-year failure-free survival (FFS), and 5-year overall survival (OS) were 82.6%, 44.1%, 41.8%, and 85.1%, respectively. Among the patients whose initial serum M protein was present or not evaluated, 37.3% of patients showed disappearance of serum M protein after various treatment. MMFS of these patients were comparable to non-secretory plasmacytoma with undetectable levels of M protein, and significantly better than patients with persistent M protein. Increase of serum M protein ≥0.1 g/dL was most predictive of treatment failure with area under the curve of 0.731.
Conclusion
Patients who eventually showed persistence of serum M protein after treatment showed worse MMFS and FFS compared to those whose serum M protein disappeared or who had initially non-secretory disease. The increase of serum M protein level ≥0.1 g/dL from current nadir was predictive of treatment failure. Therefore, regular follow-up with serum M protein is highly recommended especially unless the patient had initially non-secretory disease.
7.A Clinical Observation of Upper Gastrointestinal Bleeding, with Special Reference to Factors Influencing the Outcome.
Dong Ho SHIN ; Jung Dae SUH ; Sun Keun JEUNG ; Kwang Ick KIM ; Joon Soo HAHM ; Choon Suhk KEE ; Kyung Nam PARK
Korean Journal of Gastrointestinal Endoscopy 1984;4(1):20-27
In a study of 460 cases of upper gastrointestinal bleeding admitted in Han Yang University Hospital during the 6 year period 1978-1983 inclusive, the following results were obtained. (continue...)
Hemorrhage*
8.Dissemination and tracking of Salmonella spp. in integrated broiler operation.
Aeran KIM ; Young Ju LEE ; Min Su KANG ; Sang Ick KWAG ; Jae Keun CHO
Journal of Veterinary Science 2007;8(2):155-161
Controlling Salmonella in integrated broiler operation is complicated because there are numerous potential sources of Salmonella contamination, including chicks, feed, rodents, wild poultry operations, and the processing plant. The objective of this study was to investigate the distribution of Salmonella through all phases of two integrated broiler operations and to determine the key areas related to the control of all known sources of infection. Two different Salmonella serotypes were observed at integrated broiler chicken company A. S. enteritidis, the predominant company A isolate, was consistently found in the breeder farm, hatcheries, broiler farms, and chicken slaughterhouse. At company B, a total of six different serotypes, S. heidelberg, S. senftenberg, S. enteritidis, S. blockley, S. gallinarum, and S. virchow, were detected. Although S. heidelberg was not found in the broiler farms, it was consistently found in the breeder farm, hatcheries, and chicken slaughterhouse. In addition, S. enteritidis was found in the hatcheries, broiler farm, and chicken slaughterhouse. In order to obtain the genetic clonality, 22 S. enteritidis isolates were digested with XbaI and analyzed by pulsed-field gel electrohporesis (PFGE). A difference in the PFGE pattern was found to be related to the origin of the integrated broiler operation. These data support the critical need to control Salmonella in breeder farms and hatcheries, and demonstrate important points related to the control of infection in large-scale poultry operations of Korea.
Animal Husbandry
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Animals
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*Chickens
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DNA, Bacterial/chemistry/genetics
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Electrophoresis, Gel, Pulsed-Field/veterinary
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Female
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Food Microbiology
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Korea/epidemiology
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Poultry Diseases/epidemiology/*microbiology/transmission
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Salmonella/classification/genetics/*isolation & purification
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Salmonella Infections, Animal/epidemiology/*microbiology/transmission
9.IgG4-Related Sclerosing Mesenteritis.
Seok Joo LEE ; Cheol Keun PARK ; Woo Ick YANG ; Sang Kyum KIM
Journal of Pathology and Translational Medicine 2016;50(4):309-311
No abstract available.
Panniculitis, Peritoneal*
10.A Case of Left Ventricular Outflow Obstruction Caused by Mitral Valve Replacement.
Do Yun KIM ; Hong Keun CHO ; Ick Mo CHUNG ; Si Hoon PARK ; Seong Hoon PARK ; Gil Ja SHIN ; Byung Chul CHANG
Korean Circulation Journal 1998;28(1):113-117
The pathophysiology, clinical presentation and prognosis of left ventricular obstruction present an important cardiological problem. Various anatomical and functional abnormality can cause this phenomenon. Rarely, left ventricular outflow obstruction can result after mitral valve surgery. We experienced a case of left ventricular outflow obdtruction 13 years after mitral valve replavement. The diagnosis was made using two-dimensinal Doppler echocardiography and confirmed by cardiac catheterization. The pressure gradient across the left ventricular outflow obstruction was 96mmHg. A second mitral valve replacement was performed. Because severe fibrosis, pannis around the prosthetic mitral valve and a subaortic web were detected during the operation, the subaortic web was removes.
Cardiac Catheterization
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Cardiac Catheters
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Diagnosis
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Echocardiography, Doppler
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Fibrosis
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Mitral Valve*
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Prognosis
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Ventricular Outflow Obstruction*