Continuous attention has been developed on the anatomical variations of the axilla in anatomist and surgeon due to their clinical importance. The axillary region is an anatomical space between the lateral part of the chest wall and the medial aspect of the upper limb. During the routine dissection of embalmed cadavers, we found variant muscular slip originating from the lateral border of tendinous part of the latissimus dorsi and continuing 9 cm more crossing the axilla. And then, it inserted into the superior margin of the insertion of the pectoralis major. We considered this muscular variation as axillary arch muscle. Correct identification of the relevant anatomy and subsequent simple surgical division is curative, paying special attention to anatomical variations in this region and its clinical importance due to its close relationship to the neurovascular elements of the axilla.
Anatomists ; Axilla ; Cadaver ; Humans ; Median Nerve ; Musculocutaneous Nerve* ; Superficial Back Muscles ; Thoracic Wall ; Upper Extremity

During an educational dissection, accessory tendon of the biceps brachii muscle was found on the right side in a Korean cadaver. The short and long heads showed normal morphology and course: however, narrow tendon was originated from the posterior border of the pectoralis major muscle and was inserted into the conjoined tendon of the long head of the biceps brachii muscle. The authors describe this previously novel case report and discusses the clinical implications of such a variant.
Cadaver ; Head ; Tendons*

Purpose: Recent obstetric guidelines recommend the administration of antenatal corticosteroids in pregnant women at risk of delivering infants at a gestational age between 34 and 36 weeks. We examined the effect of incompletely administered antenatal corticosteroids on the neonatal pulmonary outcomes in late preterm infants. Methods: Late preterm infants (34+0 to 36+6 weeks gestational age) born at the Seoul National University Bundang Hospital from January 2019 to June 2020 were retrospectively enrolled. We excluded multiple births except twins, those with major congenital anomalies, deaths, or transfers to other hospitals. An incomplete course of antenatal corticosteroids was defined as one in which the first or the second dose of betamethasone was administered within 24 hours before delivery. The rates of neonatal pulmonary morbidities were compared between late preterm infants given incomplete courses antenatal corticosteroids and their peers who not given antenatal corticosteroids; these morbidities included respiratory distress syndrome and transient tachypnea of the newborn, assisted ventilation including invasive mechanical ventilation, nasal continuous positive airway pressure and high-flow nasal cannula, and admission to neonatal intensive care unit. Results: Logistic regression models were constructed while adjusting for factors which were significant in bivariate models. After adjusting for baseline maternal and neonatal characteristics, we found no significant differences in the rates of neonatal pulmonary morbidities, assisted ventilation, or admission to the neonatal intensive care unit between late preterm infants who received incomplete antenatal corticosteroid therapy and their peers who were not given any antenatal corticosteroids. Conclusion Incompletely administered antenatal corticosteroids did not significantly alter the neonatal pulmonary outcomes in late preterm infants.

The purpose of this study was to report variations of the cubital superficial vein patterns in the Korean subjects, which was investigated by using venous illuminator, AccuVein. The 200 Korean subjects were randomly chosen from the patients and staff of the Keimyung University Dongsan Medical Center in Daegu, Korea. After excluding the inappropriate cases for detecting venous pattern, we collected 174 cases of right upper limbs and 179 cases of left upper limbs. The superficial veins of the cubital fossa were detected and classified into four types according to the presence of the median cubital vein (MCV) or median antebrachial vein. The type II, presenting the both cephalic and basilic vein connected by the MCV, was most common (177 upper limbs, 50.1%). Although the most common type in male and female was different as type I (108 upper limbs, 49.3%) and type II (75 upper limbs, 56.0%), respectively, statistical significance was not detected (P=0.241). The frequency of the each types between right and left upper limbs was also not different (P=0.973). Among 154 subjects who were observed the venous pattern in the both upper limbs, 76 subjects (49.3%) had the same venous pattern. Using AccuVein to investigate the venous pattern has an advantage of lager scale examination compared to the cadaver study. Our results might be helpful for medical practitioner to be aware of the variation of the superficial cubital superficial vein.
Cadaver ; Daegu ; Female ; Humans ; Korea ; Male ; Ocimum basilicum ; Upper Extremity ; Veins*

Background and Objectives: Air pollution, particularly particulate matter (PM), has a variety of adverse effects on human health. PM is known to induce cell death through various pathways, including pyroptosis. Despite its significance, research on PM-induced pyroptosis in nasal epithelial cells remains limited. This study aimed to explore PM-induced pyroptosis in cultured human nasal epithelial cells. Methods: For the in vitro experiments, human nasal epithelial cells were cultured. Cell viability was assessed using a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, while cell death was evaluated through propidium iodide (PI) staining and lactate dehydrogenase (LDH) release measurement. Protein expression levels related to pyroptosis were examined via western blot using antibodies against NOD-like receptor family, pyrin domain containing 3 (NLRP3), cleaved caspase-1 (CASP1 P20), gasdermin D (GSDMD)-N, and glyceraldehyde phosphate dehydrogenase. Immunofluorescent staining with a CASP1 P20 antibody was conducted to visualize cellular localization. Enzyme-linked immunosorbent assay was utilized to quantify interleukin (IL)-1β and IL-18 protein levels. Results: Treatment with PM resulted in decreased cell viability, elevated LDH release, and intensified PI staining, indicating cell death. Pyroptosis was confirmed by the elevated expression of NLRP3, CASP1 P20, and GSDMD-N, along with increased levels of IL-1β and IL-18. Inhibiting the NLRP3 inflammasome with MCC950 reduced the PM-induced effects on protein expression and cytokine release, highlighting the role of the NLRP3 inflammasome in PM-triggered pyroptosis in human nasal epithelial cells. Conclusion We showed that PM triggers pyroptosis in human nasal epithelial cells, driven by NLRP3 inflammasome-dependent signaling pathways.

During an educational dissection, accessory tendon of the extensor pollicis brevis muscle was found on the left side in a Korean cadaver. The abductor pollicis longus, extensor pollicis brevis, and extensor pollicis longus muscles showed normal morphology and course: however, narrow muscle belly originated between the extensor pollicis brevis and extensor pollicis longus muscles. It crossed the anatomical snuff box and then inserted on the base of the distal phalanx of the thumb. The author describes this previously novel case report and discusses the clinical implications of such a variant.
Cadaver ; Muscles ; Tendons ; Thumb ; Tobacco, Smokeless*

For this study, medical students, intern physicians, and resident physicians, were surveyed about the application and effectiveness for medical procedure training using cadaver. In this survey, with a target population of 170 individuals, 105 individuals (61.7%) showed positive responses to learning medical procedural using cadaver. Resident physicians group (80.8%) showed relatively positive responses compared to 4(th) year medical students (58.1%) and intern physicians (47.6%); however, this did not account for any significant statistical difference. Regarding the application of cadaver to medical procedural practices, 95 individuals (62.1%) showed positive responses. Resident physicians (74.5%) had the highest percentage of positive responses compared to intern physicians (56.7%) and 4(th) year medical students (56.6%), and there was a significant statistical difference. Suture (15.7%) was ranked first as the most suitable medical procedural to be practiced on cadaver; tracheotomy and intubation came second and third respectively. This research confirmed the application and the effectiveness of cadaver for medical procedural training and the improvement of general medical procedural ability are expected if the cadaver is applied not only to medical schools but also to intern and resident physician training.
Cadaver* ; Education, Medical ; Health Services Needs and Demand ; Humans ; Intubation ; Learning ; Schools, Medical ; Students, Medical ; Sutures ; Tracheotomy

BACKGROUND AND OBJECTIVES: One of the major occupational hazards of working in the military service is being subjected to intense impulse noise, hence acoustic trauma. Acute acoustic trauma is a preventable disease, but the effective treatment modality has not been established yet. Acute acoustic traumas caused by exposure to rifle gunshot noise are common in young Korean males in the military service because of conscription policy. Through the analysis of the clinical presentation of acoustic traumas caused by rifle gunshot noise, we suggest effective preventive modalities. SUBJECTS AND METHOD: 165 soldiers who had otologic symptoms after performing regular rifle gunshot exercise without any hearing protective measures were analyzed. They all had been tested with K2 rifle. History taking, physical examination, pure-tone audiometry, and impedence audiometry, temporal MRI, and Newmann's tinnitus inventory questionnaire survey were performed. RESULTS: Most common and annoying symptom was tinnitus. The average outcome of postexposure air conduction thresholds were 22.3dB HL in the affected ear and 11.8dB HL in the unaffected ear. There was no correlation between severity of tinnitus and severity of hearing loss. Asymmetry of hearing loss related to head position during gunshot was not found. This may be due to the fact that during the mass gunshot training, each patient can be influenced by the gunshot noise of the adjacent gunner's shooting. CONCLUSION: Widening the distance between firing lanes and providing bilateral hearing protective devices against acoustic trauma must be taken into serious consideration.
Acoustics ; Audiometry ; Audiometry, Pure-Tone ; Ear ; Ear Protective Devices ; Fires ; Head ; Hearing ; Hearing Loss ; Hearing Loss, Noise-Induced ; Humans ; Male ; Military Personnel ; Noise ; Physical Examination ; Surveys and Questionnaires ; Tinnitus

Alveolar Bone Loss ; Alveolar Process ; Alveolar Ridge Augmentation ; Bone Regeneration ; Dentistry ; Female ; Humans ; Inlays ; Mandible ; Osteoblasts ; Osteogenesis ; Osteogenesis, Distraction ; Polytetrafluoroethylene ; Titanium ; Transplants

PURPOSE: The dose of drug and the size of instrument are determined based on children's weight. We aimed to validate the finger counting method (FCM) for weight estimation in Korean children using the Monte Carlo simulation. METHODS: We estimated the weight of Korean children aged 1 to 9 years by the FCM. These measurements were compared with the weight extracted by the Monte Carlo simulation applied to the “2007 Korean Children and Adolescents Growth Standard”. Pearson correlation coefficients (r) were measured to assess the correlation between the weight extracted by the simulation and that estimated by FCM. Bland-Altman analyses were performed to assess the agreement between the weight extracted by the simulation and that estimated by FCM and 2 other well-known pediatric weight estimation formulas (the Advanced Pediatric Life Support and Luscombe formulas). RESULTS: Data regarding 9,000 children's weight selected by age and gender was randomly extracted using the simulation. We found a positive correlation between the weight estimated by the FCM and the weight extracted (in boys, r = 0.896, P < 0.001; in girls, r = 0.899, P < 0.001). The FCM tended to underestimate weight in the children aged 7 years or old. CONCLUSION: This article suggests the usefulness of FCM in weight estimation, particularly in children younger than 7 years. With appreciation of the limitation in older children, the FCM could be applied to emergency practice.
Adolescent ; Body Weight ; Child ; Emergencies ; Emergency Service, Hospital ; Female ; Fingers* ; Humans ; Methods* ; Monte Carlo Method ; Resuscitation