1.Evaluation of Random Urine Sodium and Potassium Compensated by Creatinine as Possible Alternative Markers for 24 Hours Urinary Sodium and Potassium Excretion.
Hyunmin KOO ; Sang Guk LEE ; Jeong Ho KIM
Annals of Laboratory Medicine 2015;35(2):238-241
Sodium and potassium intake was assessed on the basis of its respective excretion levels in 24 hr urine samples. However, owing to the inconvenience of collection, we evaluated random spot urine for alternative sodium and potassium excretion markers. We included 250 patients who submitted 24 hr- and spot urine for clinical tests. However, 22 patients who showed 24 hr urine creatinine excretion levels <500 mg/day were excluded, because these samples possibly resulted from incomplete urine collection. Moreover, 24 patients were excluded because of their use of diuretics during the urine collection period. We observed significant correlations between 24 hr urine sodium excretion and both the sodium/creatinine (r=0.34, P<0.0001) and the sodium/specific gravity unit (SGU) ratios (r=0.19, P=0.007) in random urine samples. Similarly, 24 hr urine potassium excretion and both the spot urine potassium/creatinine (r=0.47, P<0.0001) and potassium/SGU ratios (r=0.28, P<0.0001) were significantly correlated. Although the estimated sodium/creatinine and potassium/creatinine ratios showed a significant correlation with 24 hr urine sodium and potassium excretion, respectively, further studies are required to develop a spot urine test for individualized monitoring of sodium and potassium excretion.
Biomarkers/urine
;
Creatinine/*urine
;
Humans
;
Hypertension/pathology/urine
;
Potassium/*urine
;
Sodium/*urine
;
Urinalysis
;
Urine Specimen Collection
2.The Evaluation of Recovery Rate of Neisseria gonorrhoeae in Two Bacterial Transport Swab Systems and Prevalence of Co-Infection after Delayed Transport.
Hyunmin KOO ; Younghee SEO ; Yangsoon LEE ; Hyukmin LEE ; Dongeun YONG ; Seok Hoon JEONG ; Kyungwon LEE
Annals of Clinical Microbiology 2014;17(4):110-114
BACKGROUND: Neisseria gonorrhoeae infection remains prevalent, and the emergence of antimicrobial resistance has made the treatment and control of gonorrhea more difficult. Therefore, it is important to compare isolation methods and transport media to overcome gonorrhea via epidemiologic understanding and to determine co-infection rates with other sexually transmitted diseases among primary-care hospitals. In this study, we determine the recovery rate of transferred specimens according to type of transport media and co-infection rate using PCR. METHODS: Genital specimens were collected at three primary-care hospitals from January 2010 to November 2012 using transgrow media and commercial BD transport media. Culture and multiplex PCR were conducted to isolate N. gonorrhoeae. RESULTS: Among 162 specimens, 57 (35.2%) isolates were recovered, and 146 (90.1%) specimens were positive for multiplex PCR. The recovery rate was 29.9% (78/261) using transgrow media and 19.2% (50/261) using BD transport media. The most common co-infected bacteria with N. gonorrhoeae was Chlamydia trachomatis (15.8%), followed by Mycoplasma hominis (6.2%) and M. genitalium (3.4%). CONCLUSION: Under general transport conditions, the rate of recovery of N. gonorrhoeae was as low as 19.2-29.9% depending on the type of transport media, suggesting that molecular diagnostic methods are required to detect the remaining 70% of gonorrhea-infected patients. Co-infection with other sexually transmitted diseases was not rare, and other tests for accurate additional antimicrobial regimens should also be considered.
Bacteria
;
Chlamydia trachomatis
;
Coinfection*
;
Gonorrhea
;
Humans
;
Multiplex Polymerase Chain Reaction
;
Mycoplasma hominis
;
Neisseria gonorrhoeae*
;
Pathology, Molecular
;
Polymerase Chain Reaction
;
Prevalence*
;
Sexually Transmitted Diseases
3.Development of Virtual Reality-based Visual Perception and Cognitive Rehabilitation Service
YoHan SONG ; JinCheol KIM ; JeongA LEE ; Shin HAN ; YoonGyung LIM ; HyunMin LEE
Journal of Korean Physical Therapy 2019;31(2):67-75
PURPOSE: Patients with brain damage suffer from limitations in performing the activities of daily living (ADL) because of their motor function and visual perception impairment. The aim of this study was to help improve the motor function and visual perception ability of patients with brain damage by providing them with virtual reality-based contents. The usability results of the patients and specialists group were also evaluated. METHODS: The ADL contents consisted of living room, kitchen, veranda, and convenience store, similar to a real home environment, and these were organized by a rehabilitation specialist (e.g., neurologist, physiotherapist, and occupational therapist). The contents consisted of tasks, such as turning on the living room lights, organizing the drawers, organizing the kitchen, watering the plants on the veranda, and buying products at convenience stores. To evaluate the usability of the virtual reality-based visual cognitive rehabilitation service, general elderly subjects (n=11), stroke patients (n=7), stroke patients with visual impairment (n=4), and rehabilitation specialists (n=11) were selected. The questionnaires were distributed to the subjects who were using the service, and the subjective satisfaction of individual users was obtained as data. The data were analyzed using SPSS 21.0 software. The general characteristics of the users and the evaluation scores of the experts were analyzed using descriptive statistics. RESULTS: The usability test result of this study showed that the mean value of the questionnaire related to content understanding and difficulty was high, between 4–5 points. CONCLUSION: The virtual reality rehabilitation service of this study is an efficient service that can improve the function, interest, and motivation of stroke patients.
Activities of Daily Living
;
Aged
;
Brain
;
Cognitive Therapy
;
Humans
;
Motivation
;
Physical Therapists
;
Rehabilitation
;
Specialization
;
Stroke
;
Vision Disorders
;
Visual Perception
;
Water
4.Approach to complicated fully edentulous case: from the diagnosis to the definitive denture.
Jina OH ; Hyunmin LEE ; Janghyun PAEK ; Kwantae NOH ; Kung Rock KWON ; Ahran PAE
The Journal of Korean Academy of Prosthodontics 2015;53(3):250-255
In fully edentulous cases, which are accompanied by severe residual ridge resorption and impairment of supporting tissues of complete dentures, proper diagnosis and systemic treatment planning are required for the improvement in retention, stability, and support of prosthesis. Provisional restoration, while it is unfamiliar in complete denture restoration, can be used as a valuable tool, which makes possible to evaluate the stability of complete dentures and receive feedback from patients in complex clinical situations. In this case, a provisional denture was used to improve stability of impression, polished, and occlusal surfaces of complete denture, and to consider esthetic requirements before final denture construction. The result was clinically satisfactory in terms of functional and esthetical aspects.
Denture, Complete
;
Dentures*
;
Diagnosis*
;
Humans
;
Mouth, Edentulous
;
Prostheses and Implants
5.Intraoperative allergic reaction to fentanyl: A case report.
Jin JOO ; Hyunmin BAE ; Jaemin LEE
Korean Journal of Anesthesiology 2009;57(6):776-779
Although rare, intraoperative allergic reaction can lead to significant morbidity and mortality. Clinical diagnosis is difficult as there is a need to differentiate from other causes of perioperative adverse reactions, such as side effects of administered drugs, or patients' medical conditions which may present with bronchospasm or hypotension. Intraoperative allergic reaction may be triggered by various agents. Among those, opioid-induced allergic reaction is scarcely reported. We report a case of a patient who has previously had allergic reaction to meperidine and intraoperatively showed fentanyl induced anaphylaxis or anaphylactoid reaction with literature reviews.
Anaphylaxis
;
Bronchial Spasm
;
Fentanyl
;
Humans
;
Hypersensitivity
;
Hypotension
;
Meperidine
6.Azacitidine-induced Hepatotoxicity in a Patient with Myelodysplastic Syndrome.
Jin Soo KIM ; Joo Han LIM ; Hyeon Gyu YI ; Hyunmin PARK ; Moon Hee LEE ; Chul Soo KIM
Korean Journal of Hematology 2007;42(2):176-179
Hematopoietic stem cell transplantation remains the only curative option for myelodysplastic syndrome (MDS), but the prevalence of the disease in elderly people limits broad application of the procedure, particularly in lower risk group. Azacitidine has been recently approved by the U.S. Food and Drug Administration for MDS regardless of subtype on French-American-British classification. Adverse effects of azacitidine include gastrointestinal, hematological and infusion-related reactions. Azacitidine induced hepatotoxicity has been reported mainly in patients with previous hepatobiliary disease, e.g., extensive tumor infiltration in liver, liver cirrhosis and cholelithiasis. We report here a case of azacitidine-induced hepatitis under no predisposition to hepatobiliary disease.
Aged
;
Azacitidine
;
Cholelithiasis
;
Classification
;
Hematopoietic Stem Cell Transplantation
;
Hepatitis
;
Humans
;
Liver
;
Liver Cirrhosis
;
Myelodysplastic Syndromes*
;
Prevalence
;
United States Food and Drug Administration
7.Stenting of the Left Main Coronary Artery in a Patient With Takayasu's Arteritis.
Hyo Keun LEE ; June NAMGUNG ; Won Ho CHOI ; Hyunmin CHOE ; Sung Uk KWON ; Joon Hyung DOH ; Sung Yun LEE ; Won Ro LEE
Korean Circulation Journal 2011;41(1):34-37
Management of Takayasu's arteritis of the left main coronary artery (LMCA) is difficult because of the possibility of restenosis. Clinically significant stenotic lesions must be considered anatomical correlation. Many studies have reported that the management of stenotic lesions of the LMCA with endoluminal stenting and balloon angioplasty and de-novo stenting is safe and effective for patients with Takayasu's arteritis. We report the case of a patient with Takayasu's arteritis of the LMCA. The patient had undergone two consecutive percutaneous coronary interventions because of recurrent restenosis of in-stent lesions, and eventually underwent coronary artery bypass graft (CABG) surgery for myocardial infarction in the same lesion. We suggested treatment with CABG because the pathophysiology of Takayasu's arteritis is different from that of atherosclerotic stenosis.
Angioplasty, Balloon
;
Angioplasty, Balloon, Coronary
;
Constriction, Pathologic
;
Coronary Artery Bypass
;
Coronary Artery Disease
;
Coronary Vessels
;
Humans
;
Myocardial Infarction
;
Percutaneous Coronary Intervention
;
Stents
;
Takayasu Arteritis
;
Transplants
8.Validation of the finger counting method using the Monte Carlo simulation.
Hyunsu KANG ; Youngsuk CHO ; Jinhyuck LEE ; Hyunmin CHA ; Hyunjung LEE ; Daehee CHOI ; Gyu Chong CHO ; Dongkeon LEE ; Ji Yun AHN ; Youdong SOHN
Pediatric Emergency Medicine Journal 2017;4(2):58-66
PURPOSE: The dose of drug and the size of instrument are determined based on children's weight. We aimed to validate the finger counting method (FCM) for weight estimation in Korean children using the Monte Carlo simulation. METHODS: We estimated the weight of Korean children aged 1 to 9 years by the FCM. These measurements were compared with the weight extracted by the Monte Carlo simulation applied to the “2007 Korean Children and Adolescents Growth Standard”. Pearson correlation coefficients (r) were measured to assess the correlation between the weight extracted by the simulation and that estimated by FCM. Bland-Altman analyses were performed to assess the agreement between the weight extracted by the simulation and that estimated by FCM and 2 other well-known pediatric weight estimation formulas (the Advanced Pediatric Life Support and Luscombe formulas). RESULTS: Data regarding 9,000 children's weight selected by age and gender was randomly extracted using the simulation. We found a positive correlation between the weight estimated by the FCM and the weight extracted (in boys, r = 0.896, P < 0.001; in girls, r = 0.899, P < 0.001). The FCM tended to underestimate weight in the children aged 7 years or old. CONCLUSION: This article suggests the usefulness of FCM in weight estimation, particularly in children younger than 7 years. With appreciation of the limitation in older children, the FCM could be applied to emergency practice.
Adolescent
;
Body Weight
;
Child
;
Emergencies
;
Emergency Service, Hospital
;
Female
;
Fingers*
;
Humans
;
Methods*
;
Monte Carlo Method
;
Resuscitation
9.Erratum: Current View of Orphan Drug Usage in Tertiary Hospital and Rare Incurable Disease Hospital.
Kyung Suk CHOI ; Young mi JEONG ; Yu Jeong KIM ; Yoon Hee KIM ; Hyunmin GU ; Byung Koo LEE ; Eunsook LEE ; Sandy Jeong RHIE
Korean Journal of Clinical Pharmacy 2016;26(3):267-267
Erratum agreed to by all authors, editor in chief, publisher, and scientific society.
10.The Recognition Capability of Cardiac Arrest for Lay Person, Nurse and Dispatcher: A Comparison Study through the Video Question.
Taewan KIM ; Youngsuk CHO ; Jinhyuck LEE ; Hyunmin CHA ; Hyunjung LEE ; Daehee CHOI ; Gyu Chong CHO
Journal of the Korean Society of Emergency Medicine 2017;28(6):635-642
PURPOSE: The rapid recognition of cardiac arrest is an important factor for survival in cardiac arrest patients, and gasping is a primary barrier to the recognition of a cardiac arrest. This study examined differences in capability of recognizing a cardiac arrest and gasping among lay people, hospital nurses, and medical dispatchers. METHODS: From January to July 2016, 193 participants (65 lay people 62 hospital nurses, and 66 medical dispatchers) watched video clips of a collapsed virtual patient with unresponsiveness, gasping or seizure and answered a questionnaire asking whether the patient was in cardiac arrest or not. The results of the questionnaire were analyzed and compared among the groups. RESULTS: The total score of the questionnaire on the determination of cardiac arrest among lay people, nurses, and medical dispatchers were significant (3.09±1.43 vs. 4.15±1.22 vs. 4.45±1.29 points, p < 0.01). In the questions regarding cardiac arrest with gasping, the correct answer rate was highest in the dispatchers, followed in order by nurses and lay people (82.5% vs. 54.8% vs. 29.7%, p < 0.001). CONCLUSION: In this study, lay people had the lowest recognition capability of a cardiac arrest and gasping among the groups. In addition, gasping is a meaningful barrier to cardiac arrest recognition for both lay people and healthcare providers.
Cardiopulmonary Resuscitation
;
Health Personnel
;
Heart Arrest*
;
Humans
;
Respiration
;
Seizures