1.Pazopanib-induced Hair Depigmentation, Ulcerative Patch in a Patient with Metastatic Renal Cell Carcinoma.
Youngil KIM ; Hyungrock KIM ; Hyunjung KWON ; Joonsoo PARK ; Hyun CHUNG ; Kyungduck PARK
Korean Journal of Dermatology 2016;54(7):581-582
No abstract available.
Carcinoma, Renal Cell*
;
Hair*
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Humans
;
Ulcer*
2.A Reinforced Endotracheal Tube Completely Severed by a Patient Bite and Lodged in the Right Main Bronchus.
Susie YOON ; Hyunjung CHOO ; Se Eun KIM ; Heeyeon KWON ; Hannah LEE
Korean Journal of Critical Care Medicine 2017;32(1):70-73
Reinforced endotracheal tubes (ETTs) are designed to resist kinking or compression. However, these have a potential risk of being obstructed or severed by a patient's bite. We report a case in which a reinforced ETT was severed by tube-bite while the patient was in the prone position during an intensive care unit stay. Bronchoscopic evaluation showed that the severed distal part of the tube had lodged in the patient's right main bronchus, and it had to be surgically removed. The patency of reinforced ETTs should be carefully monitored in patients intubated in the prone position.
Airway Obstruction
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Bronchi*
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Bronchoscopy
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Humans
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Intensive Care Units
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Intubation
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Patient Rights
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Prone Position
3.Non-Enhancing Intradural Extramedullary Ependymoma: A Case Report
Jaemin KIM ; Hyunjung KIM ; Hyeongju KWON
Journal of the Korean Radiological Society 2021;82(5):1341-1345
Spinal ependymomas are generally located in the intramedullary compartment in adults. Intradural extramedullary spinal ependymomas are extremely rare. Spinal ependymomas show various contrast enhancements on MRI. In this study, we report a rare case of a 52-year-old female who had a pathologically confirmed intradural extramedullary ependymoma that showed no enhancement on MRI.
4.Non-Enhancing Intradural Extramedullary Ependymoma: A Case Report
Jaemin KIM ; Hyunjung KIM ; Hyeongju KWON
Journal of the Korean Radiological Society 2021;82(5):1341-1345
Spinal ependymomas are generally located in the intramedullary compartment in adults. Intradural extramedullary spinal ependymomas are extremely rare. Spinal ependymomas show various contrast enhancements on MRI. In this study, we report a rare case of a 52-year-old female who had a pathologically confirmed intradural extramedullary ependymoma that showed no enhancement on MRI.
5.Investigating Effects of Nano- to Micro-Ampere Alternating Current Stimulation on Trichophyton rubrum Growth.
Dong Rak KWON ; Hyunjung KWON ; Woo Ram LEE ; Joonsoo PARK
Annals of Dermatology 2016;28(5):575-578
BACKGROUND: Fungi are eukaryotic microorganisms including yeast and molds. Many studies have focused on modifying bacterial growth, but few on fungal growth. Microcurrent electricity may stimulate fungal growth. OBJECTIVE: This study aims to investigate effects of microcurrent electric stimulation on Trichophyton rubrum growth. METHODS: Standard-sized inoculums of T. rubrum derived from a spore suspension were applied to potato dextrose cornmeal agar (PDACC) plates, gently withdrawn with a sterile pipette, and were applied to twelve PDACC plates with a sterile spreader. Twelve Petri dishes were divided into four groups. The given amperage of electric current was 500 nA, 2 µA, and 4 µA in groups A, B, and C, respectively. No electric current was given in group D. RESULTS: In the first 48 hours, colonies only appeared in groups A and B (500 nA and 2 µA exposure). Colonies in group A (500 nA) were denser. Group C (4 µA) plates showed a barely visible film of fungus after 96 hours of incubation. Fungal growth became visible after 144 hours in the control group. CONCLUSION: Lower intensities of electric current caused faster fungal growth within the amperage range used in this study. Based on these results, further studies with a larger sample size, various fungal species, and various intensities of electric stimulation should be conducted.
Agar
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Electric Stimulation
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Electricity
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Fungi
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Glucose
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Sample Size
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Solanum tuberosum
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Spores
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Trichophyton*
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Yeasts
6.Comparison of Microleakage and Compressive Strength of Different Base Materials
Eunyeong JANG ; Jaesik LEE ; Soonhyeun NAM ; Taeyub KWON ; Hyunjung KIM
Journal of Korean Academy of Pediatric Dentistry 2021;48(2):168-175
This study compared the microleakages and compressive strengths of various base materials.
To evaluate microleakages, 50 extracted permanent premolars were prepared. The teeth divided into 5 groups of 10 each according to the base materials. Cavities with a 5.0 mm width, 3.0 mm length, and 3.0 mm depth were formed on the buccal surfaces of the teeth. After filling the cavities with different base materials, a composite resin was used for final restoration. Each specimen was immersed in 2% methylene blue solution and then observed under a stereoscopic microscope (× 30). To evaluate the compressive strength, 5 cylindrical specimens were prepared for each base material. A universal testing machine was used to measure the compressive strength.
The microleakage was highest in the Riva light cureTM group and lowest in the BiodentineTM and Well-RootTM PT groups. For the compressive strengths, in all groups, acceptable strength values for base materials were found. The highest compressive strength was observed in the Fuji II LCTM group and the lowest strength in the Well-RootTM PT group.
7.Repopulation of autophagy-deficient stromal cells with autophagy-intact cells after repeated breeding in uterine mesenchyme-specific Atg7 knockout mice
Ji-Eun OH ; Sojung KWON ; Hyunji BYUN ; Haengseok SONG ; Hyunjung Jade LIM
Clinical and Experimental Reproductive Medicine 2023;50(3):170-176
Objective:
Autophagy is highly active in ovariectomized mice experiencing hormone deprivation, especially in the uterine mesenchyme. Autophagy is responsible for the turnover of vasoactive factors in the uterus, which was demonstrated in anti-Müllerian hormone receptor type 2 receptor (Amhr2)-Cre-driven autophagy-related gene 7 (Atg7) knockout (Amhr-Cre/Atg7f/f mice). In that study, we uncovered a striking difference in the amount of sequestosome 1 (SQSTM1) accumulation between virgin mice and breeder mice with the same genotype. Herein, we aimed to determine whether repeated breeding changed the composition of mesenchymal cell populations in the uterine stroma.
Methods:
All female mice used in this study were of the same genotype. Atg7 was deleted by Amhr2 promoter-driven Cre recombinase in the uterine stroma and myometrium, except for a triangular stromal region on the mesometrial side. Amhr-Cre/Atg7f/f female mice were divided into two groups: virgin mice with no mating history and aged between 11 and 12 months, and breeder mice with at least 6-month breeding cycles with multiple pregnancies and aged around 12 months. The uteri were used for Western blotting and immunofluorescence staining.
Results:
SQSTM1 accumulation, representing Atg7 deletion and halted autophagy, was much higher in virgin mice than in breeders. Breeders showed reduced accumulation of several vasoconstrictive factors, which are potential autophagy targets, in the uterus, suggesting that the uterine stroma was repopulated with autophagy-intact cells during repeated pregnancies.
Conclusion
Multiple pregnancies seem to have improved the uterine environment by replacing autophagy-deficient cells with autophagy-intact cells, providing evidence of cell mixing.
8.Histopathologically Confirmed Tinea Capitis Misdiagnosed as Psoriasis.
Barnali CHOWDHURY ; Osung KWON ; Hyungrok KIM ; Hyunjung KWON ; Kyungduck PARK ; Hyun CHUNG ; Joonsoo PARK
Korean Journal of Medical Mycology 2016;21(4):135-137
No abstract available.
Psoriasis*
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Tinea Capitis*
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Tinea Favosa
;
Tinea*
9.A Case of Candida Balanitis Masquerading as Herpes Genitalis.
Yong Woo CHOI ; Hyungrok KIM ; Hyunjung KWON ; Moon Hyung YOU ; Jong Soo CHOI ; Hyun CHUNG ; Joonsoo PARK
Korean Journal of Medical Mycology 2017;22(4):167-171
A 46-year-old male presented with skin lesion on the tip of penis, occurring a month ago. Erythematous macules and grouped vesicles on the glans penis and upper side of prepuce area were noticed. In addition, scales were noticed on the tip of glans penis. The lesion was first diagnosed as herpes genitalis based on the clinical manifestation, but had failed to improve with systemic and topical antiviral and topical antibiotics. KOH examinations were performed on his upper glans penis, and we detected pseudo hyphae and spores. Fungal culture and polymerase chain reaction (PCR) study were revealed as Candida albicans. He was successfully treated with topical isoconazole cream twice a day. Candida balanitis refers to candida infections of glans penis. Infectious balanitis presented various clinical presentations, it is not easy to diagnose with clinical presentation only. Therefore, it is essential to include other examination such as KOH examination, microorganism exam, and/or biopsy in the differential diagnosis when cutaneous lesions are noticed in patients. Herein, we present a candida balanitis with atypical features that clinically mimicked herpes genitalis.
Anti-Bacterial Agents
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Balanitis*
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Biopsy
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Candida albicans
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Candida*
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Diagnosis, Differential
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Herpes Genitalis*
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Humans
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Hyphae
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Male
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Middle Aged
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Penis
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Polymerase Chain Reaction
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Skin
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Spores
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Weights and Measures
10.Small GTPases and formins in mammalian oocyte maturation: cytoskeletal organizers.
Clinical and Experimental Reproductive Medicine 2011;38(1):1-5
The maturation process of mammalian oocytes accompanies an extensive rearrangement of the cytoskeleton and associated proteins. As this process requires a delicate interplay between the cytoskeleton and its regulators, it is often targeted by various external and internal adversaries that affect the congression and/or segregation of chromosomes. Asymmetric cell division in oocytes also requires specific regulators of the cytoskeleton, including formin-2 and small GTPases. Recent literature providing clues regarding how actin filaments and microtubules interact during spindle migration in mouse oocytes are highlighted in this review.
Actin Cytoskeleton
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Animals
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Asymmetric Cell Division
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Cytoskeleton
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GTP Phosphohydrolases
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Humans
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Mice
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Microtubules
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Monomeric GTP-Binding Proteins
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Nerve Tissue Proteins
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Oocytes
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Proteins