No abstract available.
Humans

No abstract available.

This study was attempted mainly to estimate the frequency of ichthyoses and its genetic characteristics among general population in Chonnam Province. One hundredand thirtyone subjects heing comprised of 121 with ichthyosis vulgaris, 6 with X-linked recessive ichthyosis and 4 with lamellar ichthyosis visited the department of Dermatology, Chonnam National University Hospital from 1971 through 1980. All except 7 patients had visited the hospital with chief complaints of a skin problem other than ichthyoses itself. The frequency of ichthyosis vulgaris seems to be somewhere between, 1/300 and 1/400. 86% were found to either be sporadic cases or come from families from which not enough information was obtained to define a mode of inheritance. The fact that 43% of the sibling of affected patients developed ichthyosis vulgaris points out that it is a highly penetrant autosomal dominant, disease. Skipped generation was observed in 2 families, and gonadal mosaicism in 1 family. Atopic diseaaes were found only in 12.0% of cnses of ichthyosis vulgaris. The disease appeared in 81% of cases before 1 year af age. The skin lesions of ichthyoses were developed on the lower limhs, back, upper limbs, abdomen and scalp in the order of frequency.
Abdomen ; Dermatology ; Gonads ; Humans ; Ichthyosis Vulgaris ; Ichthyosis* ; Ichthyosis, Lamellar ; Jeollanam-do ; Mosaicism ; Scalp ; Siblings ; Skin ; Upper Extremity ; Wills

No abstract available.
Suicide, Attempted*

No abstract available.
Phospholipases* ; Protein Kinase C* ; Protein Kinases* ; Psychotropic Drugs* ; Type C Phospholipases*

No abstract available.
Humans

BACKGROUND: Cosmetics are one of the common causes of contact dermatitis and many new cosmetic products are being introduced rapidly into our market. OBJECTIVE: Our purpose was to investigate the as is patch test result by several factors including age, cosmetic product and atopic diseases, and to compare as is patch result with those of standard and cosmetic patch tests. METHODS: The records of 240 patients were reviewed who had been patch tested with their own cosmetics and toiletries with a clinical impression of cosmetic contact dermatitis at the patch clinic of Kangnam St. Mary's Hospital in the period of 1991-1995. RESULTS: Of the 95 patients who were tested with European standard series 54 (56.8%) showed a positive reaction and nickel sulfate was the most common allergen. Eighteen (38.3%) of the 47 patients tested with a cosmetic series revealed a positive reaction and imidazolidinyl urea and dodecyl gallate were the most common allergens. In as is patch test, 99 (41.3%) of the 240 patients showed a positive reaction to 248 (7.3%) of the 3403 cosmetics. Common cosmetic products showing positive reactions were skin care products (26.2%), face make-ups (19.8%), and hair preparations (16.9%). There was no statistically significant difference in the positive reaction rate between atopy and non-atopy patients. The positive correlation rate of as is test with standard and cosmetic series was relatively low. CONCLUSION: Commercial standard patch test series including cosmetic series are not enough to detect causative allergen in cosmetic contact dermatitis. As is patch test should be encouraged to detect new allergens, because many cosmetic ingredients are developed and introduced in market.
Allergens ; Dermatitis, Contact* ; Hair Preparations ; Humans ; Nickel ; Patch Tests* ; Skin Care ; Urea

No abstract available.
Histiocytosis, Langerhans-Cell* ; Myelodysplastic Syndromes* ; Skin

Following the Korean War, the presence of foreign troops in Korea and lowered. sexual morality caused an increase in the rate of prostitution and related venereal diseases. Though the health authorities made efforts to handle these problems, they didnt obtain any noticeable results, because they neglected the scientific prevention and treatment based on expert knowledge, and the sociopsychological problem, which was the basic cause of the increment in the rate of prostitution. They only took administrative action against the prostitutes. Therefore, in July, 1976, we went to a town(named Silver Town) located on the outskirts of a U.S. Air Force base, and, examined and guestioned a number of prostitutes. Each of the 288 subjects residing in the town was given a questionaire that dealt with individual living attitudes, family and social background, and sociopsychological aspects of tbeir lifestyle. Questionaires were completed anonymously. Serological tests for syphilis, the UDRL and TPHA, were also administered. The results of our atudy are as follows. 1) Most of the prostitutes had grown up in large families, in which females were predominant. Because of economic difficulties they dropped out of school a.t an early age and became prostitutes. The average age of a prostitute at the time of her first sexual experience was 19. 9 years, the expriences usually taking place with her first boyfriend. Forty six psrcent of tbe subjects had intercourse for the first time between the ages of 15 and 19. Fortynine & two tenths percent of them because prostitutes within one year of their initial sexual act, and all of them at an average interval of 2.5 years following the first sexual experience, the average age being 22. 4 years. 2) The longer the women had worked as prostitutes, the more they felt dissatisfied with their work, and the more they desired to change to an occupation which was healthier and entailed more self-respect. 3) Out of 283 subjects, 39% had a history of venereal disease, predominantly of gonorrhea. Tbe results of the STS administered to all subjects were,; VDRL 7.7% positive and TPHA 6% positive. It was also concluded that the subjects had no educational or working knowledge of venereal diseases.
Anonyms and Pseudonyms ; Female ; Gonorrhea ; Humans ; Jeollabuk-do* ; Korea ; Korean War ; Life Style ; Morals ; Occupations ; Prostitution ; Serologic Tests ; Sex Workers* ; Sexually Transmitted Diseases ; Silver ; Syphilis*

A fifty-seven-year-old, faers wife, was affected a skin lesion of dark pigme raised, crusted ulerated, easy to bleed on touching the crust and indurated ur with mood consistancy, and the tumor was located over the inner is of left eye, which was alike to malignant melanoma clinically. The tumor 1-shaped and measure 1.;. m x l. 7cm in diameter, which did not make any itchy sensation. d with small papule about 8 years ago which zdually increased. in siiarate3 with ocsional ble 3ing. Her skin lesion was treateQ with curretation and electrodessication or surgical removement by loca.l practitioner, however, it recured after the each treatments. In this hospital, the peeived the skin biopsy of the tumor and the diagnosis was established as cell car.cinoma histopathologically, and the tumor was removed by ical technique applying transposition skin flap from the infra-orbitale face, and the result was satisfactory without "mcurence until upto bservation (for three years and three months). On the conclusion, ad a case of Solid pigmented basal cell carcin- oma resernbling maligna. with histopathological study and treated with plastic surgical management very satisfying result.
Biopsy ; Carcinoma, Basal Cell* ; Diagnosis ; Humans ; Melanoma* ; Sensation ; Skin ; Spouses