1.Clinical studies on risk factors of preterm delivery.
Ey Seob SIM ; Tae Hyung KIM ; Myung Jin KIM ; Yong Bong KIM ; Sung Kwan PARK
Korean Journal of Perinatology 1993;4(4):504-511
No abstract available.
Risk Factors*
2.A Case of Rosai-Dorfman Disease Limited to the Lip.
Kee Suck SUH ; Young Seung JEON ; Hyung Jun SIM ; Sung Hee KIM ; Sang Tae KIM
Annals of Dermatology 2004;16(4):194-196
No abstract available.
Histiocytosis, Sinus*
;
Lip*
3.Clinicopathologic Findings of Metastatic Skin Cancer.
Sung Hee KIM ; Young Seung JEON ; Hyung Jun SIM ; Kee Suck SUH ; Sang Tae KIM
Korean Journal of Dermatology 2004;42(3):300-308
BACKGROUND: The incidence of metastatic skin cancer has been reported to be relatively low. Because the diagnosis is not so difficult, cutaneous metastasis could be an important clue to discover the hidden internal malignancy, if found before recognizing primary cancer, or play a significant role to determine therapeutical plans and prognosis if found after diagnosis of primary cancer. MATERIAL AMD METHODS: This study was made upon the 68 cases of metastatic skin cancer, which had been confirmed histopathologically in the department of dermatology, Kosin University Gospel hospital from January, 1986 to August, 2003. Age and sex distributions, sites of primary cancer, time of detection, localization of the lesions, morphologic and histopathologic findings were examined by the review of medical records, clinical photographs, and pathologic slides. RESULTS: 1. The mean age at the time of diagnosis was 56.6 years and most patients were distributed over 5 decades. The male to female ratio was 1: 1.3. 2. Metastasis from breast carcinoma consisted of 19 cases, this was the most common primary cancer, followed by lung cancer, melanoma, and stomach cancer. In men, lung cancer and stomach cancer were the most common primary neoplasm, while breast cancer was the most frequent in women. 3. 50 of the cases were detected after diagnosis of primary cancer and during therapy. The other 18 cases were detected before the internal malignancy was recognized. 4. The localization of metastatic skin cancer was widespread over the whole body. The majority of cutaneous metastasis was predisposed to the surface near primary cancer, but distant metastases such as alopecia neoplastica on the scalp were also observed. 5. The most common morphologic features were single or multiple nodules, while inflammatory and indurated plaques were also found. 6. Histopathologic examination revealed that adenocarcinoma was the most common pathologic type, followed by squamous cell carcinoma and melanoma. The histopathologic features of cutaneous metastasis generally mimicked that of primary tumors. CONCLUSION: Generally, metastatic skin cancer is detected after the diagnosis of primary cancer showing subsequent treatment failure and poor prognosis. In some cases, however, cutaneous metastasis can be the earliest sign to recognize internal malignancy. Especially in the cases of metastatic skin cancer originating from the kidney, liver and thyroid gland, cutaneous features are the most significant evidences to presume the site of origin without any other findings. Therefore, it is important to recognize the clinical and histopathologic findings of metastatic skin cancer for the most successful diagnostic, therapeutic and prognostic determination.
Adenocarcinoma
;
Alopecia
;
Breast Neoplasms
;
Carcinoma, Squamous Cell
;
Dermatology
;
Diagnosis
;
Female
;
Humans
;
Incidence
;
Kidney
;
Liver
;
Lung Neoplasms
;
Male
;
Medical Records
;
Melanoma
;
Neoplasm Metastasis
;
Prognosis
;
Scalp
;
Sex Distribution
;
Skin Neoplasms*
;
Skin*
;
Stomach Neoplasms
;
Thyroid Gland
;
Treatment Failure
4.Desmoid Tumor Following Augmentation Mammoplasty with Silicone Implants.
Woo Shik JEONG ; Tae Suk OH ; Hyung Bo SIM ; Jin Sup EOM
Archives of Plastic Surgery 2013;40(4):470-472
No abstract available.
Female
;
Fibromatosis, Aggressive
;
Mammaplasty
;
Silicones
5.A Case of Secondary Syphilis Showing a Histological Pattern of Interstitial Granuloma Annulare.
Sang Tae KIM ; Soo Young CHOI ; Young Seung JEON ; Hyung Jun SIM ; Kee Suck SUH
Korean Journal of Dermatology 2005;43(12):1650-1652
No abstract available.
6.Results of Protocol-based Perioperative Management in Off-Pump Coronary Artery Bypass Grafting for Patients with Non-dialysis-dependent Chronic Kidney Disease.
Jeong Won KIM ; Hyung Tae SIM ; Jae Suk YOO ; Dong Jin KIM ; Kwang Ree CHO
The Korean Journal of Thoracic and Cardiovascular Surgery 2016;49(6):427-434
BACKGROUND: Recent studies have demonstrated the benefits of off-pump coronary bypass grafting over the on-pump technique in patients with chronic kidney disease (CKD). To further reduce the risk of acute kidney injury and the need for renal replacement therapy, even in patients undergoing off-pump coronary artery bypass grafting, we adopted protocol-based perioperative management for patients with CKD. METHODS: From December 2012 to March 2015, 265 patients underwent isolated off-pump coronary artery bypass grafting. To analyze renal function in a stable condition, we excluded 12 dialysis-dependent end stage renal failure and 10 emergency or urgent cases. Among the remaining 243 patients, 208 patients had normal kidney function (normal group), and 35 patients had CKD (CKD group). Minimizing contrast exposure, ensuring adequate hydration, using strict drug dosage adjustment, and optimizing hemodynamic status were key elements of the protocol for the CKD group. RESULTS: The risk of acute kidney injury was about ×3 higher in the CKD group than in the normal group (p=0.01). Estimated glomerular filtration rates and serum creatinine levels deteriorated until the third postoperative day in the CKD group. However, by adopting protocol-based perioperative management, this transient renal dysfunction recovered to preoperative levels by the fifth postoperative day without requiring renal replacement therapy in all cases. CONCLUSION: Off-pump coronary bypass surgery combined with this protocol-based perioperative management strategy in patients with non-dialysis-dependent CKD could mostly be performed without renal replacement therapy.
Acute Kidney Injury
;
Coronary Artery Bypass
;
Coronary Artery Bypass, Off-Pump*
;
Creatinine
;
Emergencies
;
Glomerular Filtration Rate
;
Hemodynamics
;
Humans
;
Kidney
;
Perioperative Care
;
Renal Insufficiency
;
Renal Insufficiency, Chronic*
;
Renal Replacement Therapy
;
Transplants*
7.A Case of Glucagonoma Syndrome Diagnosed as Necrolytic Migratory Erythema.
Kee Suck SUH ; Su Young CHOI ; Young Seung JEON ; Hyung Jun SIM ; Seun Ja PARK ; Sang Tae KIM
Korean Journal of Dermatology 2005;43(6):856-859
Necrolytic migratory erythema (NME) is a typical cutaneous manifestation of glucagonoma syndrome. The entire syndrome consists of NME, glucose intolerance, weight loss, anemia, glossitis, diarrhea, and increased glucagon levels. We herein report a patient with glucagonoma syndrome who was diagnosed as having NME. A 48-year-old male presented with a 2-month history of painful erythematous, desquamative, erosive papules and plaques on both lower extremities. Histological examination revealed an intraepidermal cleft, the presence of vacuolated, pale epidermal cells, and necrosis in the upper epidermis. His glucagon level was 2650 pg/ml, with the upper limit of a normal range being 250 pg/ml. The patient was treated with octreotide, and showed an improvement of the skin eruption with normalization of the glucagon level within 4 weeks.
Anemia
;
Diarrhea
;
Epidermis
;
Glossitis
;
Glucagon
;
Glucagonoma*
;
Glucose Intolerance
;
Humans
;
Lower Extremity
;
Male
;
Middle Aged
;
Necrolytic Migratory Erythema*
;
Necrosis
;
Octreotide
;
Reference Values
;
Skin
;
Weight Loss
8.A Case of Keratoacanthoma on the Lower Lip.
Sang Tae KIM ; Hyoe Jin ROH ; Soo Young CHOI ; Young Seung JEON ; Hyung Jun SIM ; Kee Suck SUH
Korean Journal of Dermatology 2006;44(2):235-237
Keratoacanthoma is a rapidly growing cutaneous tumor with a histopathologic pattern often suggestive of a squamous cell carcinoma (SCC). It may be viewed as an aborted malignancy which only rarely progresses into an aggressive SCC. It is most likely arising from hair follicle that has the tendency of spontaneous resolution. The diagnosis of keratoacanthoma is based on clinical, histopathologic features and biologic behavior. A 75-year-old woman presented with a 1-month history of a rapidly enlarging exophytic tumor on the lower lip. A biopsy was performed leading to a diagnosis of keratoacanthoma. We report a case of keratoacanthoma on the lower lip, because the mucosal area is an unexpected location.
Aged
;
Biopsy
;
Carcinoma, Squamous Cell
;
Diagnosis
;
Female
;
Hair Follicle
;
Humans
;
Keratoacanthoma*
;
Lip*
9.Control of clonorchiasis by repeated praziquantel treatment and low diagnostic efficacy of sonography.
Sung Tae HONG ; Kisung YOON ; Mejeong LEE ; Min SEO ; Min Ho CHOI ; Jung Suk SIM ; Byung Ihn CHOI ; Chong Ku YUN ; Soon Hyung LEE
The Korean Journal of Parasitology 1998;36(4):249-254
In Korea, Clonorchis sinensis infection is still highly prevalent because case detection in the field is difficult and the detected cases used to be incompletely cured due to treatment failure. The present study tried to control clonorchiasis in an endemic village by repeated treatments with praziquantel every 6 months and to evaluate sonography as a diagnostic measure. By stool examinations, the egg positive rate in the endemic village was 22.7%, but it decreased to 19.6% at 6 months, 15.1% at 12 months. 12.2% at 18 months, 6.3% at 24 months, 11.4% at 30 months, and 6.3% at 42 months after the beginning of repeated praziquantel administration. The sonography showed 61 (49.6%) positive cases of 123 screened residents: among egg-positives the sonography positive rate was 52.2% and among egg-negatives it was still 49%. The rate among cured cases was 64.3% after 6 months, 50.0% after 12 months, 50.0% after 18 months, and 66.7% after 24 months. In a non-endemic village, 64 residents were found egg-negative by fecal examination, but 20 (31.3%) of them were positive by sonography. The present findings indicate that control of clonorchiasis in an endemic village by repeated praziquantel treatment for 42 months is still insufficient and sonography is of little value for diagnosis of clonorchiasis.
Animal
;
Antiplatyhelmintic Agents/administration & dosage*
;
Clonorchiasis/ultrasonography*
;
Clonorchiasis/prevention & control
;
Clonorchiasis/epidemiology
;
Follow-Up Studies
;
Human
;
Korea/epidemiology
;
Parasite Egg Count
;
Praziquantel/administration & dosage*
;
Prevalence
;
Sensitivity and Specificity
;
Treatment Failure
10.A Case of Kikuchi's Disease (Histiocytic Necrotizing Lymphadenopathy) Showing Typical Histopathologic Findings in Cutaneous Lesion.
Sung Hee KIM ; Hyung Jun SIM ; Ki Seung DOH ; Min Soo JANG ; Kee Suck SUH ; Sang Tae KIM
Korean Journal of Dermatology 2003;41(12):1703-1705
Kikuchi's disease(Histiocytic necrotizing lymphadenitis) is an idiopathic, self-limiting disease typically affecting cervical lymph nodes in young adults. Cutaneous involvement has been reported in 16-40%. We report a case of Kikuchi's disease in 10-year-old female that showed asymptomatic erythematous papules on the face accompanied by cervical lymphadenopathy. The histopathologic examination of the skin revealed diffuse dermal lymphohistiocytic infiltrate, a large amount of nuclear dust with absence of neutrophils, which is characteristic of Kikuchi's disease. In general, histopathologic findings of skin biopsy show a mirror image of that of lymph nodes involved in Kikuchi's disease. Therefore, it is important to recognize cutaneous manifestations of this entity, because we can avoid invasive lymph node biopsy. if skin lesions involved show typical histopathologic findings of Kikuchi's disease.
Biopsy
;
Child
;
Dust
;
Female
;
Histiocytic Necrotizing Lymphadenitis*
;
Humans
;
Lymph Nodes
;
Lymphatic Diseases
;
Neutrophils
;
Skin
;
Young Adult