1.A Survey of the Outcome of Childhood Asthma.
Hyung Ja PARK ; Myung Ik LEE ; Sun Wha KIM ; Don Hee AHN ; Keun Chan SOHN
Journal of the Korean Pediatric Society 1987;30(1):55-63
No abstract available.
Asthma*
2.A Case of pseudoglucagonoma Syndrome Treated with Medium-chain Triglyceride.
Kyung Hyung SEO ; Jung Hum PARK ; Ho Sun JANG ; Kyung Sool KWON ; Tae Ahn CHUNG
Korean Journal of Dermatology 1997;35(3):593-599
Necrolytic migratory erythema is a rare, distinctive, necrotizing cutaneous eruption usually associated with glucagonoma, an alpha-cell tumor of the pancreas. Other clinical features include ane- mia, diabetes mellitus and weight loss. However, it also occurrs without the pancreatic glucagonoma. So this rare condition is called pseudoglucagonoma syndrome, and has been described in association with chronic hepatic diseases, malabsorption with villous atrophy, chronic pancreatitis, celiac sprue, hypoproteinemia and odontogenic infection. We report a case of pseudoglucagonoma syndrome induced by malnutrition without glucagonoma. A 28-year-old Korean female was referred to our department complaining of multiple erythematous, desquamative, crusted and erosive patches on the extremities, and diffuse scalp alopecia for 5 years. She also had perianal erosion, angular cheilitis without glossitis, amenorrhea, axillary and pubic hair loss, and weight loss. Six years previously she had had Whipples operation for a pancreatic solid and papillary neoplasm. The laboratory data showed hypoalbuminemia, essential fatty acid deficiency, diabetes mellitus and slightly high levels of zinc and glucagon. A skin biopsy showed irregular acanthosis, epidermal edema and pallor, dyskeratosis, areas of superficial epidermal necrosis and vascular dilatation of the papillary dermis. The patient improved dramatically after intravenous hyperalimentation and oral intake of mediurn chain triglyceride. For 2.5 years she has taken medium-chain triglycerides without any other treatment, and no side effects on recurrence has been observed.
Adult
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Alopecia
;
Amenorrhea
;
Atrophy
;
Biopsy
;
Celiac Disease
;
Cheilitis
;
Dermis
;
Diabetes Mellitus
;
Dilatation
;
Edema
;
Extremities
;
Female
;
Glossitis
;
Glucagon
;
Glucagonoma
;
Hair
;
Humans
;
Hypoalbuminemia
;
Hypoproteinemia
;
Malnutrition
;
Necrolytic Migratory Erythema*
;
Necrosis
;
Pallor
;
Pancreas
;
Pancreatitis, Chronic
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Parenteral Nutrition, Total
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Recurrence
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Scalp
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Skin
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Triglycerides*
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Weight Loss
;
Zinc
3.Three Cases of Nephrogenic Diabetes Insipitus.
Hey Sun LEE ; Byoung Hai AHN ; Jong Jin SEO ; Hyung Ro MOON
Journal of the Korean Pediatric Society 1984;27(9):912-917
No abstract available.
4.A Case of Pedunculated Pigmented Eccrine Poroma Combined with Congenital Melanocytic Nevus on the Scalp.
Kyung Hyung SEO ; Ho Sun JANG ; Kyung Sool KWON ; Tae Ahn CHUNG
Korean Journal of Dermatology 1997;35(1):169-173
It has been generally assum d that eccrine poroma arises from acrosyringium, the epidermal sweat duct unit. Eccrine poroma mainly involves the non hairy surfaces of the skin, but it has also been found on hair-bearing areas. One of the characteristics of this structure is absence of melanocytes and melanin granules arnong its cells. However a complete absence of melanocytes and melanin granules in eccrine poroma is not invariable and a few reports of such an occurrence have been presented. The authors report herein a case of unusual and rare eccrine poroma. The eccrine poroma had melanin pigment and melanocytes, was pedunculated and occurred on the parietal scalp which was the unusual site of involvement. The eccrine poroma was also combined with a pedunculated congenital melanocytic nevus on the supraauricular scalp.
Melanins
;
Melanocytes
;
Nevus, Pigmented*
;
Poroma*
;
Rabeprazole
;
Scalp*
;
Skin
;
Sweat
5.TISSUE EXPANSION FOR HAIR REPLACEMENT SURGERY AND TREATMENT OF MALE PATTERN BALDNESS.
Hyung Jun KIM ; Sang Hwan KOO ; Duk Sun AHN ; Byung Kyu SOHN
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1997;24(4):839-846
No abstract available.
Alopecia*
;
Hair*
;
Humans
;
Male*
;
Tissue Expansion*
6.Assessment of Genotoxic Hazard in Petrochemical Workers.
Jai Dong MOON ; Soon Phal SUH ; Jung Sun PARK ; Jin Hyung CHO ; Ki Won AHN
Korean Journal of Occupational and Environmental Medicine 1998;10(1):53-60
In order to evaluate the genotoxic hazard among workers potentially exposed to low level petrochemical substances, the analyses of micronuclei (MN) and sister chromatid exchanges (SCEs) in lymphocytes were performed in 46 male workers (as exposed group) and 46 nonexposed subjects (as control group). Mean frequencies of MN and SCEs (respectively, 12.9/1000 cells and 6.5/cell) in exposed group were very significantly higher than those (10.2/1000 cells and 5.4/cell) in control group. And there were also significant differences in mean frequencies of MN and SCEs adjusted for age, employment duration, smoking, and drinking between two groups. Median frequencies of MN and SCEs in exposed group were very significantly higher than those in control group. Frequencies of SCEs were higher in smokers than in non-smoker. Frequencies of MN in smokers, however, were similiar to those of non-smoker. Interaction between exposure and smoking on MN and SCEs induction was not observed. The results suggest that there is genotoxic hazard in high risk group like workers handling carcinogens in petrochemical plants and the analyses of MN and SCEs are useful biomarkers for the exposure to hazard substances even at the level below the exposure limit.
Biological Markers
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Carcinogens
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Drinking
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Employment
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Humans
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Lymphocytes
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Male
;
Sister Chromatid Exchange
;
Smoke
;
Smoking
7.Standard Setting in Student Assessment by Criterion Referenced Evaluation.
Korean Journal of Medical Education 2001;13(1):41-45
Licensure, credentialling and academic institutions are seeking new innovative approaches to the assessment of professional competence. Central to these recent initiatives is the need to determine standards of performance, which separated the competent from the non-competent candidate. The goal of this study is to introduce the criterion referenced standard-setting methods to medical Schools. The authors used Angoff and Jaeger method, which are the simplest absolute standard setting methods. In this study, the cut-off score estimated by Jaeger method was higher than that of Angoff method.
Humans
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Licensure
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Professional Competence
;
Schools, Medical
8.A Case of Niemann-Pick Disease with Sea-Blue histiocytes in the Bone Marrow.
Young Sun KIM ; Soo Heum LIM ; Jeong Kee SEO ; Hyo Seop AHN ; Hyung Ro MOON
Journal of the Korean Pediatric Society 1985;28(12):1238-1244
No abstract available.
Bone Marrow*
;
Histiocytes*
;
Niemann-Pick Diseases*
9.Comparative study on postoperativeevaluation methods of knee ligament injuries.
Key Yong KIM ; Woo Shin CHO ; Sung Il BIN ; Hyung Sun AHN
The Journal of the Korean Orthopaedic Association 1993;28(3):948-954
No abstract available.
Knee*
;
Ligaments*
10.Quantity and Quality Assessment of Randomized Controlled Trials Published in Five Korean Medical Journals, from 1980 to 2000.
Suk Won KIM ; Youn Seon CHOI ; Hyung Sik AHN ; Hoi Young LEE ; Duck Sun AHN ; Young Mee LEE
Journal of the Korean Academy of Family Medicine 2004;25(2):118-125
BACKGROUND: As evidence-based medicine is getting popular recently, the importance of randomized controlled trial as a research methodology is also getting highlighted. This study was conducted in order to identify the status quo of randomized controlled trial research in major domestic journals and to provide baseline data for constructing Korean clinical trial database such CCTR (Cochrane Clinical Trial Registry). METHODS: Five journals issued by domestic publication industry were selected, out of which 127,560 original articles, equal to 253 volumes, were investigated. The author extracted the articles, which performed prospective clinical trial, targeting human beings. The selected papers were analyzed with experts to single out randomized controlled trial among them. Furthermore, the quality of the re-selected ones were assessed according to Jadad Quaility Assessment Scale. RESULTS: After analysis, it turned out that the number of papers adopting prospective clinical trial were 406 volumes (3.2%) of 12,760 and that they increased from 157 in 1980s to 224 in 1990s. However, the percentage of prospective clinical trial monographs, introduced during 1980s and 1990s, remained 2.0 to 4.0. The number of randomized controlled trial-based papers were 115, accounting for 0.9% of total articles. The number of RCT increased to approximately two fold from 1980s to 1990s. Quality analysis showed that among a total of 115 RCT papers, those of scoring 1 and 3 were 16 (13.9%), 82 articles obtained score 2 (72.2%). There was no papers, which won the marks of 4 and 5. CONCLUSION: It was found that domestic randomized controlled trial research was weak both in number and quality. Therefore, it is necessary to activate clinical medicine study with good quality to upgrade the amount and quality of monographs.
Clinical Medicine
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Evidence-Based Medicine
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Humans
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Publications
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Research Design