OBJECTIVES: This paper presents the information on the incidence of cancer from the population-based cancer resistry in Kangwha County. Material and METHODS: This investigation is based on Kangwha cancer registry. The data included cases of cancer diagnosed from 1986 through 1992. The diagnosis of cancer was confirmed by a team of physicians and nurses with the medical records kept in the clinics and hospitals based on the diagnostic criteria recommended by WHO. Home visitings were also made to cancer patients confirmed in every 6 months for the follow up and for the collection of relevant information directly from the patients. RESULTS: A total of 992 cancer cases were registered during 1986 - 1992. The age-adjusted cancer incidence rate of all site is 201.7 in men and 110.7 in women. The most common cancer is the stomach cancer in both sexes. The age-adjusted incidence rate of the stomach cancer is 65.9 in men and 25.0 in women per 100,000 population. The lung cancer(33.8) and liver cancer(27.7) are next common cancers in men. The cervical cancer(21.8) and lung cancer(8.4) are next in women. CONCLUSION: The most common cancer is the stomach cancer in both sexes. The annual age-adjusted incidence rate of the stomach cancer is 65.9 in men and 25.0 in women per 100,000 population.
Diagnosis ; Female ; Follow-Up Studies ; House Calls ; Humans ; Incidence* ; Liver ; Lung ; Male ; Medical Records ; Stomach Neoplasms

OBJECTIVES: The previous assumption that patients with bipolar I disorder make a full recovery of cognitive function in the euthymic phase has been challenged by studies that suggest neuronal changes, and recently persisting neuropsychological dysfunctions beyond episodes of the illness. The aim of the present study was to investigate the impairment of the neurocognitive performance of euthymic bipolar patients, the characteristics of cognitive impairment, and the relationship between cognitive dysfunction and clinical variables of illness in bipolar population. METHODS: 19 bipolar out-patients who had been euthymic for more than 3 months by Hamilton Depression Scale score below 7 and Young Mania Rating Scale score below 6 were compared with age- and education- matched 19 healthy subjects on neurocognitive tests. Patients showing observable extrapyramidal symptoms were excluded with the objective rating. The following tests were administered in according to cognitive domain: Korean-Wechsler Adult Intelligence Scale, subtests among Wechsler Memory Scale-Revised, Wisconsin Card Sorting Test, and Signal Detection/Decision-Reaction Timer/Psychomotor Performances among Vienna Test System. RESULTS: The bipolar group performed significantly lower than the control group on verbal and performance IQ, total IQ, and psychomotor function or coordination. There was no relationship between the cognitive impairment and clinical course of illness, except duration of neuroleptic exposure. CONCLUSIONS: Although our findings did not replicate the recently reported results, especially in the domain of executive function and verbal memory, they suggested the presence of neurocognitive difficulties, in the general ability and visuomotor function in stable bipolar patients. Also, we tailed to identify the influence of clinical course variables on cognitive area with statistically signficant differences.
Adult ; Bipolar Disorder ; Depression ; Executive Function ; Humans ; Intelligence ; Memory ; Neurons ; Outpatients ; Wisconsin

BACKGROUND: Early conversion from intravenous to oral antibiotics plays an important role in lowering the risk of catheter-associated infections, reducing the workload of nurses, decreasing direct and indirect costs, and shortening hospital stays. In August 2015, an antimicrobial stewardship program (ASP) was implemented to facilitate conversion from intravenous to oral administration of fluoroquinolones in our institute. This study evaluated the clinical and economic impact of the intervention. MATERIALS AND METHODS: Data were retrospectively collected by reviewing electronic medical records. All hospitalized patients aged 18 and older who met the study inclusion criteria for the conversion were included between August and November 2015. We computed the physicians’ adherence rate to the ASP recommendations. We also measured the total use of fluoroquinolones, length of hospital stay, and medication costs. RESULTS: During 4 months, 129 cases were enrolled in the study. The adherence rate was 79.8%. The average total prescription volume of intravenous fluoroquinolones, the length of hospital stay, and the total cost of the fluoroquinolones statistically significantly decreased in the intervention-adherent group. CONCLUSION: Intervention to facilitate conversion from intravenous to oral administration has reduced excess use of intravenous fluoroquinolones and length of hospital stay. With these findings, further implementations of the ASP extending to other antibiotics may be warranted.
Administration, Oral ; Anti-Bacterial Agents ; Catheter-Related Infections ; Electronic Health Records ; Fluoroquinolones* ; Humans ; Length of Stay ; Prescriptions ; Retrospective Studies ; Viperidae