1.Immunohistochemical studies on the rate of positive reaction of estrogen receptors and progesterone receptors in the breast diseases.
Suk Yong SUNG ; Hyun Muck LIM ; Jae Hyung YOO
Journal of the Korean Surgical Society 1991;41(1):29-36
No abstract available.
Breast Diseases*
;
Breast*
;
Estrogens*
;
Progesterone*
;
Receptors, Estrogen*
;
Receptors, Progesterone*
2.CT and MR findings of mycotic infection of the paranasal sinus: differentiation from sinonasal neoplasm.
Kil Woo LEE ; Hyo Keun LIM ; Gwy Suk SEO ; Suk Soo BAE ; Shin Hyung LEE
Journal of the Korean Radiological Society 1992;28(2):176-181
When a soft tissue mass in the bony wall of the paranasal sinus is present, it is difficult to make a distinction between tumor and inflammatory mass on CT. Fungal sinusitis may have soft tissue attenuation on the bony wall of the sinus, bony sclerosis, focal bony destruction, and calcific area on CT. This is a report of four proven cases of fungal sinusitis, asperogillosis in 3 cases and mucormycosis in 1 case, All 4 patients had CT and one patient had MRI, On CT, bony sclerosis and destruction were well visualized in all cases. On MRI, mycetoma in the maxillary sinus was hypointense on T1 weighted images and more hypointense on T2 weighted images. Although CT appears to be the best modality for initial examination of the patient with sinusitis, the differentiation of fungal sinusitis from tumor mass or other entity may be better accomplished with MRI.
Humans
;
Magnetic Resonance Imaging
;
Maxillary Sinus
;
Mucormycosis
;
Mycetoma
;
Sclerosis
;
Sinusitis
3.Boundary of Anxiety Disorders: Obsessive-Compulsive Disorder and Schizophrenia.
Journal of Korean Neuropsychiatric Association 2008;47(6):525-532
Although obsessive-compulsive disorder (OCD) is recognized as a major psychiatric illness, few studies have investigated obsessive-compulsive symptoms in patients with schizophrenia. Recent increases in dual diagnosis due to changes to the DSMIV diagnostic criteria, findings of obsessive-compulsive symptoms (OCS) after administration of atypical antipsychotics, increased reports of co-occurrence of schizophrenia and OCD have increased the interest in OCS in schizophrenia. The incidence of OCS in patients with schizophrenia is reported to be 3-59%; however, the rate of progression to schizophrenia from OCD is not higher than in the general population. Level of insight, which differentiates obsessions from delusions, can be confounded by the specifier 'with poor insight' in OCD. OCD with schizotypal personality disorder or poor insight differs from pure OCD in that it responds poorly to treatment, has a poor prognosis, leads to deficits in cognitive functioning similar to those observed in schizophrenia, and responds well to low-dose antipsychotics. In the past, it was believed that OCS could prevent or delay the deteriorative course of schizophrenia. However, recent studies have shown that co-occurrence of OCD and schizophrenia increases the severity of symptoms, delays the treatment response, and reduces socio-occupational functions. Schizophrenia and OCD share the same pathophysiology in that both diseases have defects in the fronto-basal functional circuitry of the brain. The use of serotonin and dopamine has been addressed in schizophrenia due to the use of atypical antipsychotics in patients with schizophrenia. The finding of drug-induced OCS suggested that the two diseases share a similar pathogenesis involving neurotransmitters. Further studies are needed to make an exact diagnosis between the two diseases and to determine the common pathophysiology between OCD and schizophrenia.
Antipsychotic Agents
;
Anxiety
;
Brain
;
Delusions
;
Diagnosis, Dual (Psychiatry)
;
Dopamine
;
Humans
;
Incidence
;
Neurotransmitter Agents
;
Obsessive Behavior
;
Obsessive-Compulsive Disorder
;
Prognosis
;
Schizophrenia
;
Schizotypal Personality Disorder
;
Serotonin
4.Bile duct changes in rats reinfected with Clonorchis sinensis.
Dongil CHOI ; Sung Tae HONG ; Shunyu LI ; Byung Suk CHUNG ; Jae Hoon LIM ; Soon Hyung LEE
The Korean Journal of Parasitology 2004;42(1):7-17
This study describes an evaluation of the sonographic, cholangiographic, pathological, and immunological findings, and the protective effect shown by rats reinfected with Clonorchis sinensis. Eight experimental rat groups were, namely, a normal control, a primary infection control, a reinfection I (reinfection 7 week after treatment following 3-week infection), a reinfection II (reinfection 2 week after treatment following 8-week infection), a reinfection III (exploration of the intrahepatic bile ducts 1 week after reinfection 4 week after treatment following 4-week infection), a superinfection, a secondary infection control, and an infection following immunization group. Sonographic and cholangiographic findings showed moderate or marked dilatation of the bile duct confluence in the primary infection control, reinfection II, and secondary infection control groups. Juvenile worms survived in the intrahepatic bile ducts 1 week after reinfection following treatment in the reinfection III group. It was concluded that reinfecting juvenile worms found during the first week following reinfection failed to survive or grow further. Anatomical, pathophysiological, or immunological changes may induce protection from reinfection in rats.
Animals
;
Anthelmintics/administration & dosage/therapeutic use
;
Antibodies, Helminth/blood
;
Antigens, Helminth/administration & dosage/immunology
;
Bile Duct Diseases/parasitology/*pathology/ultrasonography
;
Bile Ducts, Intrahepatic/parasitology/*pathology/ultrasonography
;
Cholangiography
;
Clonorchiasis/parasitology/*pathology/ultrasonography
;
Clonorchis sinensis/*pathogenicity
;
Immunization
;
Praziquantel/administration & dosage/therapeutic use
;
Rats
;
Rats, Sprague-Dawley
;
Sound Spectrography
;
Support, Non-U.S. Gov't
5.Normal Values of rNeonatal Periumbilical Skin Length.
Young Pyo CHANG ; Hyung Suk LIM ; Hye Won PARK ; Woong Huen KIM ; Hee Ju KIM
Journal of the Korean Pediatric Society 1994;37(7):924-927
Malformations of umbilicus are a feature of many dysmorphic syndromes and the measurement of periumbilical skin length should be considered as the basic step in the description of the umbilical malformations. So, we measured the periumbilical skin length in the 103 normal neonates and obtained the following results. 1) The means (+SD) of the periumbilical skin length were the 11.7mm (+3.0) in the cranial site and the 8.2mm (+2.5) in the caudal site, and the cranial length was 3.5mm longer than the caudal length. 2) No difference was observed between the male and female groups in the periumbilical skin length. 3) Age was the only statistically significant variable associated with the periumbilical skin length and it was observed that the periumbilical skin length decreased according to the advance of age (hour).
Female
;
Humans
;
Infant, Newborn
;
Male
;
Reference Values*
;
Skin*
;
Umbilicus
6.Normal predicted values of pulmonary function test in Korean school-aged children.
Kyung Ae YOON ; Hyung Suk LIM ; Young Yull KOH ; Heon KIM
Journal of the Korean Pediatric Society 1993;36(1):25-37
In recent years pulmonary function teste have had a wide application in clinical pulmonary diseases. By combining a number of different pulmonary function tests, abnormality present in a particular pa tient can be defined. This narrows the list of possible diagnosis and allows to determine accurately the degree of impairment and assess the pesponse to therapy. To assess the pulmonary function in a patient and label as abnormal, it becomes important to define the range of expected values for a normal population. These normal'predicted values'vary according to sex and prowth, i.e., age, height, and weight, particularly in children. In addition, race and geography have been consistently shown to bc an important determinant of lung function. In order to obtain normal perdicted values of pulmonary function tests in Korean school-aged children, we performed spirometry-based pulmonary function tests on the normal healthy 2022 children, age from 6 through 15, and analyzed the data, with the parameters such as sex, age, height, weight, and body surface area. We calculated each of their simple and complex linear and logarithmic regression equations setting the predicted values. The results are as follows: 1) Predicted values of pulmonary function test items were generally higher in boys than those of girls. 2) A correlation coefficient to the parameters examined was the highest in FEV1, then those of FVC, FEF25,PEFR, FEF50, MMEF, AND FEF75 follow in order. 3) Of the parameters examined, height had the highest correlation coefficient consistently in all pulmonary function test items. 4) As compared with the inland and overseas data, some differences were observed.
Body Surface Area
;
Child*
;
Continental Population Groups
;
Diagnosis
;
Female
;
Geography
;
Humans
;
Lung
;
Lung Diseases
;
Respiratory Function Tests*
7.Clinical study of transient synovitis of the hip joint in children.
Hyung Soo KIM ; Young LIM ; Young Uck KIM ; Han Suk KO ; Byung Jik KIM
The Journal of the Korean Orthopaedic Association 1991;26(1):175-179
No abstract available.
Child*
;
Hip Joint*
;
Hip*
;
Humans
;
Synovitis*
8.A Comparison of Effectiveness of Gracey Curet and Ultrasonic Curet on Subgingival Scaling and Root Planning.
Suk Hyung CHUNG ; Chin Hyung CHUNG ; Sung Bin LIM
The Journal of the Korean Academy of Periodontology 2001;31(1):257-267
Removal of subgingival calculus is essential for the success in periodontal treatment. Subgingival instrumentation is used for the removal of all bacterial plaque and calculus. In this study, Gracey curet and Ultrasonic curet were used on single rooted teeth to conduct subgingival scaling and root planning. The remaining amount of calculus was evaluated according to type of instrument, depth of pocket, and tooth surface. 24 teeth were extracted from 14 patients being treated at department Periodontology Seoul Advantist dental hospital were used. Total 96 area(4 surface per teeth) were evaluated. 12 teeth treated with Gracey curet were used as the control group and the other 12 teeth treated with Ultrasonic curet were examined for experimental group. The 4 surfaces of the teeth(buccal, mesial, lingual or palatal, distal) were observed through the stereomicroscope and the images of the surface were captured and saved in CCD. The images were displayed on the monitor and the amount of calculus remained was evaluated by overlapping 10x10 grid pixel screen produced by Microsoft power point. The results evaluated were as follows 1. There was no statistically significant difference in residual calculus and tooth position following scaling and root planning of all group, but statistically significant correlation with residual calculus, probing depth, instruments and tooth surface. 2. There was statistically significant correlation between residual calculus and probing depth, but no statistically significant difference in residual calculus, tooth surface and tooth position on experimental(Ultrasonic curet) group. 3. There was no statistically significant difference in residual calculus according to the pre-treatment pocket depth and tooth position, but statistically significant correlation with tooth surface. The amount of residual calculus increase with mesial, distal, buccal and lingual(or palatal) surface on control(Gracey curet) group. 4. The Gracey curet showed better results than ultrasonic curet in mesial and distal surface, and there is significant difference. The results demonstrate that ultrasonic curet alone is inadequate for thorough subgingival debridement and suggest that Ultrasonic curet with Gracey curet should be more effective.
Calculi
;
Debridement
;
Dental Scaling*
;
Humans
;
Seoul
;
Tooth
;
Ultrasonics*
9.The use of water as an oral contrast agent for CT study in stomach cancer.
Hak Won CHO ; Hee Suk LEE ; An Lee LIM ; Seung Hyeun KIM ; Shin Hyung LEE ; Chang Joon LEE
Journal of the Korean Radiological Society 1991;27(5):699-703
No abstract available.
Stomach Neoplasms*
;
Stomach*
;
Water*
10.Correlation of Exercise-Induced Bronchoconstriction to PC20 and Maximal AirwayNarrowing on the Dose-Response Curve to Methacholine.
Hyung Suk LIM ; Kyung Ae YOON ; Young Yull KOH
Tuberculosis and Respiratory Diseases 1995;42(2):165-174
BACKGROUND: Exercise is one of the most common precipitants of acute asthma encountered in clinical practice. The development of airflow limitation that occurs several minutes after vigorous exercise, i. g. exercise-induced bronchoconstriction(EIB), has been shown to be closely correlated with the nonspecific bronchial hyperresponsiveness, which is the hallmark of bronchial asthma. All previous reports that assessed the correlation of EIB to nonspecific bronchial hyperresponsiveness have focused on airway sensitivity(PC20) to inhaled bronchoconstrictor such as methacholine or histamine. However, maximal airway narrowing(MAN), reflecting the extent to which the airways can narrow, when being exposed to high dose of inhaled stimuli, has not been studied in relation to the degree of EIB. METHODS: Fifty-six children with mild asthma(41 boys and 15 girls), aged 6 to 15 years(mean +/- SD, 9.9 +/- 2.5 years) completed this study. Subjects attended the laboratory on two consecutive days. Each subject performed the high-dose methacholine inhalation test at 4 p.m. on the first day. The dose-response curves were characterized by their position(PC20) and MAN, which was defined as maximal response plateau(MRP: when two or three data points of the highest concentrations fell within a 5% response range) or the last of the data points(when a plateau could not be measured). On the next day, exercise challenge, free running outdoors for ten minutes, was performed at 9 a.m.. FEV1 was measured at graduated intervals, 3 to 10 minutes apart, until 60 minutes after exercise. Response(the maximal DeltaFEV1 from the pre-exercise value) was classified arbitrarily into three groups; no response ((-) EIB: DeltaFEV1 <10%), equivocal response ((+/-)EIB:10% < DeltaFEV1, <20%) and definite response((+) EIB: DeltaFEV1 >20%). RESULTS: 1) When geometric mean PC20 of the three groups were compared, PC20 of (+) EIB group was significantly lower than that of (-)EIB group. 2) There was a close correlation between PC20 and the severity of EIB in the whole group(r= -0.568, p<0.01). 3) Of the total 56 subjects, MRP could be measured in 36 subjects, and the MRP of these subjects correlated fairly with the severity of EIB(r= 0.355, p<0.05) 4) The MAN of (+) EIB group was significantly higher than that of (-)EIB group(p<0.01). 5) The MAN correlated well with the severity of EIB in the whole group(r=0.546, p<0.01). CONCLUSION: The degree of MAN as well as bronchial sensitivity (PC2o) to methacholine is correlated well with the severity of EIB. The results suggest that the two main components of airway hyperresponsiveness may be equally important determinants of exercise reactivity, although the mechanism may be different from each other. The present study also provides further evidence that EIB is a manifestation of the increased airway reactivity characteristic of bronchial asthma.
Asthma
;
Bronchoconstriction*
;
Child
;
Histamine
;
Humans
;
Inhalation
;
Methacholine Chloride*
;
Running