No abstract available.

A 18-year-old male patient presented with the skin colored, dome-shaped, soft, movable mass in his left retroauriculr region. The mass has slowly increased in size since birth. Histopathologic exarnination revealed sebaceous gland, eccrine gland and crosssectioned hair in the surrounding tissue, hair shaft projected into the lumen, and laminated horny material in the cyst. Transitional zone between stratified squarnous epithelium and the wall lined by histiocytes showed homogenous degenerative change. After surgical removal of the lesion, no recurrence was observed during 15 months of follow-up.
Adolescent ; Dermoid Cyst* ; Eccrine Glands ; Epithelium ; Follow-Up Studies ; Hair ; Histiocytes ; Humans ; Male ; Parturition ; Recurrence ; Sebaceous Glands ; Skin

Using the 8 strains of Vibrio vulnificus isolated from the patients with primary sepsis, the viability of Vibrio vulnificus were studied in the various range of hydrogen ion concentration. The opitimal pH range of growth was 7-9, and survived between pH 3. 6 and 12. 5 when incubated at 37C for one hour.
Humans ; Hydrogen* ; Hydrogen-Ion Concentration* ; Protons* ; Sepsis ; Vibrio vulnificus* ; Vibrio*

One hundred patients of osmidrosis were treated by surgical procedure at the Department of Dermatology, Wonkwang University Hospital. The methods of operative treatment were elliptical excision for 37(74), bipedicle incision with apocrine glancl undercutting for 14(28), and single incision wit.h apocrine gland undercutt,ing for 49 (98). The results were summarized as follows : 1. Of the 74 axillae treated by elliptical excision, one occurred recurrence, and 1.7 showed complication, hematoma in 6, infection and delayed union in 4, each necrosis and severe scar in one each, 2. Of the 28 axillae treated by bipedicle incision with apocrine gland undercutting, 6 showed complication; hematoma in 4, infection and delayed union in one each 3. Of t..he 98 axillae treated by single incision with apocrine gland undercutting, 5 showed complication, hematoma in 3, infection and delayed union in one each In conclusion, single incision with apocrine gland undercutting was found to be more excellent compared with the other surgical methods.
Apocrine Glands ; Axilla ; Cicatrix ; Dermatology ; Hematoma ; Humans ; Necrosis ; Recurrence

PURPOSE: To evaluate clinical and radiological results and to analyse the parapatellar complications after endoscopic anterior cruciate ligament reconstruction using central one-third bone-patellar tendon-bone autografts. MATERIALS AND METHODS: 66 cases among 158 consecutive cases from Feb 1990 to May 1996 were reviewed and evaluated with regard to patellofemoral pain, crepitus, quadriceps atrophy, graft donor site complication, Lysholm knee scoring system and radiological assessment. The average period of follow up was 23 months (range, 12-57 months) and the average age at operation was 31 years old (range, 18-58 years). RESULTS: The average Lysholmn knee score improved from 57.5 points preoperatively to 91.3 points at follow up. The instrumented anterior laxity test showed that excellent anterior stability was regained in most patients. There were many cases of parapatellar complications, 7 cases (10.6%) of anterior knee pain, 21 cases (32.8%) of crepitus, 43 cases (65.1%) of quadriceps weakness, 29 cases (45.3%) of graft donor site paresthesia and 15 cases (23.4%) of pain on kneeling. CONCLUSIONS: Although endoscopic ACL reconstruction using central one-third bone-patellar tendon-bone autografts had good clinical results, many parapatellar complications were noted. In order to prevent these complications, different reconstruction techniques and graft materials should be considered
Adult ; Anterior Cruciate Ligament Reconstruction ; Atrophy ; Autografts* ; Follow-Up Studies ; Humans ; Knee ; Paresthesia ; Tissue Donors ; Transplants

This presentation is a case of osteomalacia, the cause of which was a nutritional deficiency. The patient was a 42-year-old female who had pseudofractures of ribs, ulnae, pelvic raml, the right second metacarpai bone and both femoral necks. Following treatment by medication combined with internal fixation of the femoral necks, the result was good.
Adult ; Female ; Femur Neck ; Humans ; Malnutrition ; Osteomalacia ; Ribs ; Ulna

Complications after surgical treatment of trochanteric fracture such as varus deformity or delayed union are frequent and there are many difficulties to maintain the stability of fragments because of the cortical deficit or comminution on medial aspect of the neck and posterior trochanteric fragment. Evans, Dimon, Sarmiento and others suggested several methods of internal fixation, furthermore it is attempted recently to reduce the fragments anatomically with sliding compression hip screw and plate. 31 cases of interal fixation on trochanteric fracture were carried out from March, 1972 to February 1979 at the Orthopaedic Department of Seoul Adventist Hospital and their comparable results were as follows. 1. Acceptable placement of metals was noted 2 cases of 6 cases in Smith-Petersen nail with Thornton plate fixation, 2 cases out of 8 cases in Smith-Petersen nail with McLaughlin plate fixation and 9 cases out of 14 cases in sliding compression hip screw and plate fixation. 2. Complications after internal fixation such as varus deformity and delayed union were noted 1 case out of 3 cases in multiple pinning, 3 cases out of 6 cases in Smith-Petersen nail with Thornton plate fixation, 4 cases out of 8 cases in Smith-Petersen nail with McLaughlin plate fixation, 4 cases out of 14 cases in sliding compression hip screw and plate fixation. 3. Required weeks in union were 18 weeks in Multiple pinning, 20 weeks in Smith-Petersen nail with Thornton plate fixation, 25 weeks in Smith-Petersen nail with McLaughlin plate fixation and 16 weeks in sliding compression hip screw and plate fixation. 4. There are few complications in treatment of trochanteric fracture with surgical procedure using Sliding compression hip screw and plate.
Adult ; Clinical Study ; Congenital Abnormalities ; Femur ; Hip ; Humans ; Metals ; Neck ; Seoul

Fractures of tibia are often trouble-some because of their easy compounding and associated soft tissue injury, especially neurovascular tissue. Initial proper treatments for fractures of tibia with severe compounding are very important for a better prognosis. In the orthopaedic Department of the Seoul Adventist Hospital, open reduction and internal fixation with Sherman plate were performed for 12 cases of tibia with severe compounding from January 1975 to October 1980 and the results were as follows; 1. The age of the patients ranged from 11 years to 50 years, and the majority of the patients were injuryed in traffic accident. 2. All of the patients were suffered from combined injures, so intensive close treatment was needed but 2 patients expired. 3. 7 out of 12 cases were found as vascular rupture and therefore 2 B-K amputations were carried out because of necrosis. 4. Average time for bone union was 6.9 months and infection was controlled without sequela. 5. Outcome of open reduction and internal fixation with Sherman plate for fractures of tibia with severe compounding was rather good, but comparisons are thought to be required after standardization of patients for open reduction without internal fixation. and openreduction with internal fixation.
Accidents, Traffic ; Amputation ; Clinical Study ; Humans ; Necrosis ; Prognosis ; Rupture ; Seoul ; Soft Tissue Injuries ; Tibia ; Tibial Fractures

No Abstract Available.
Health Behavior*

Adjuvant hormonal therapy is used as the first target-specific approach in curing breast cancers due to its high efficacy and mild side effects. Five years of tamoxifen therapy has been the gold standard for women with estrogen receptor-positive breast cancer irrespective of age or menopausal and nodal status. After the emergence of 3rd generation aromatase inhibitors (AI), the use of either tamoxifen or tamoxifen plus ovarian function suppression for 5 years has been proposed as an acceptable standard for premenopausal women while AI should form part of standard endocrine therapy for the postmenopausal women as established at the St. Gallen Concensus Conference. The addition of luteinizing-hormone-releasing hormone (LHRH) analogs might be beneficial for the younger patients who remain premenopausal after chemotherapy, however controversies over the addition of LHRH analogs remains. Further, it has been suggested that CYP2D6 polymorphisms and concomitant use of CYP2D6 inhibitors which reduce CYP2D6 activity may influence the clinical outcomes of adjuvant tamoxifen therapy. The androgen receptor has been evaluated as a prognostic or predictive marker for endocrine responsiveness in a few studies; however, there are many issues to be answered and ongoing clinical trials will provide the answers. Until then, it would be important for clinicians to carefully evaluate the risk factors of patients, monitor the compliance of those patients who are under endocrine therapy, and take care in selecting antidepressants when coprescription with tamoxifen is necessary. In the future, tailored therapy will be designed based on the target molecular profiling of the tumors, pharmacogenomics, and improved understanding of receptor signaling biology. More attention should be given to explore molecular markers that could differentiate the subsets for tailoring.
Antidepressive Agents ; Antineoplastic Agents, Hormonal ; Aromatase Inhibitors ; Biology ; Breast ; Breast Neoplasms ; Compliance ; Cytochrome P-450 CYP2D6 ; Estrogens ; Female ; Gonadotropin-Releasing Hormone ; Humans ; Organothiophosphorus Compounds ; Pharmacogenetics ; Receptors, Androgen ; Risk Factors ; Tamoxifen