The field of renal transplantation has undergone continual evolution to become the standard treatment for patients with end-stage renal diseases. The attempts to improve organ shortage, studies for clinical and basic science, empirical trial of new immunosuppressive drugs and technical challenges are very important for the development of renal transplantation medicine and improved patient outcome. This review will focus on the recent advancement and current hot issues of living donor renal transplantation worldwide.
Humans ; Kidney Transplantation* ; Living Donors*

No abstract available.
Liposarcoma, Myxoid*

No abstract available.
Rhinoplasty*

No abstract available.
Bone Conduction* ; Ear, Middle* ; Otitis Media* ; Otitis* ; Pathology* ; Temporal Bone*

No abstract available.
Cartilage* ; Rabbits* ; Ribs*

No abstract available.
Nasal Cavity* ; Solitary Fibrous Tumors*

No abstract available.
Dinoprostone*

BACKGROUND AND OBJECTIVES: Telomeres are specialized structures found at the ends of eukaryotic chromosomes. Telomeres stabilize the chromosome and protect DNA from illegitimate recombination. Telomerase is a ribonucleoprotein, a RNA dependent DNA polymerase, and acts as a reverse transcriptase-like enzyme, which maintains telomere length by adding telomeric repeat units of TTAGGG to the telomeric end. These telomeric repeat units have been found only in cells with unlimited replicative potential such as sperm cells, immortalized cell lines and cancer tissues, but not in normal somatic cells. Telomerase is believed to be characteristic of and may be the best indicator of cell immortality. This study was performed to indentify the role of telomerase activity in the multistep carcinogenesis of oral squamous cell carcinoma. MATERIALS AND METHODS:We performed a telomeric repeat amplification protocol assay in 10 oral leukoplakia, 5 tongue cancers and 10 normal oral mucosa tissues. RESULTS: All the five tongue cancer tissues showed telomerase activity. Although telomerase activity was detected in 9 of 10 oral leukoplakia tissues and in 9 of 10 normal oral mucosa tissues, the activity of telomerase was low compared to that of cancer tissues by semiquantitative analysis. CONCLUSION: These findings suggest that telomerase maybe play a key role in multistep carcinogenesis of oral malignancy. Telomerase activity was detectable in normal oral mucosa with renewal activity suggested that this enzyme might be an indicator of cell proliferation.
Carcinogenesis ; Carcinoma, Squamous Cell ; Cell Line ; Cell Proliferation ; DNA ; Leukoplakia, Oral* ; Mouth Mucosa ; Mouth Neoplasms ; Recombination, Genetic ; Ribonucleoproteins ; RNA-Directed DNA Polymerase ; Spermatozoa ; Telomerase* ; Telomere ; Tongue Neoplasms

Trilateral retinoblastoma is a syndrome involving midline intracranial malignancies in children with the heritable form of retinoblastoma. It is rare and usually lethal in spite of aggressive treatments. We report a case of trilateral retinoblastoma with review of the literature to gain further insight into this uncommon disease.
Child ; Humans ; Neuroectodermal Tumors, Primitive ; Retinoblastoma*

BACKGROUND AND OBJECTIVES: As septal surgery is being performed more and more often, the incidence of septal perforation as a complication arising from the surgery has also increased. In septal surgery, if corresponding mucoperichondrial tears occurred on both sides, autologous cartilage is usually placed between the injured mucopercondrium. However, septal perforation is sometimes found after septal surgery even after this effort. The aims of this study were to introduce a new technique for the prevention of septal perforation during septal surgery using inferior turbinate mucosa and fibrin glue and to determine its usefullness by evaluating the treatment outcome. MATERIALS AND METHODS: Between June 2005 and May 2007, 358 cases of septal surgery were performed. Bilateral mucoperichondrial tears on corresponding areas occurred in 26 cases. In Group 1 (15 cases), autologous cartilage was inserted between injured mucoperichondrium. In Group 2 (11 cases), autologous cartilage was inserted and then was repaired using fibrin glue and inferior turbinate mucosa. The authors compared the perforation rate between the two groups. RESULTS: In Group 1, septal perforation occurred in 7 of 15 patients (46.7%) and in Group 2, 1 of 11 patients (9.0%) had perforation. Perforation rates were significantly lower in Group 2. CONCLUSION: The technique of using fibrin glue and inferior turbinate mucosa may be an easy, effective method for the prevention of septal perforation during septal surgery.
Cartilage ; Fibrin ; Fibrin Tissue Adhesive ; Humans ; Incidence ; Mucous Membrane ; Turbinates