Keratoacanthoma is a benign, self limited epithelial tumor which is resemble to squamous cell carcinoma clinically and histopathologically. We have experienced a case of solitary Keratoacanthoma 48-year old female which involved left upper cheek, Diagnosis was made by characteristic clinical symptom, and. histopathologic finding.
Carcinoma, Squamous Cell ; Cheek ; Diagnosis ; Female ; Humans ; Keratoacanthoma ; Middle Aged

We present a case of multiple trichoepithelioma associated with milia. A 12-year-old girl developed symmetrically distributed, numerous, skin-colored papules on her face, some of which were studded with milia-like whitish materials. Histopathological findings of these lesions revealed the typical findings of trichoepitheliomas with overlying milia in the upper dermis.
Child ; Dermis ; Female ; Humans

Irritant or allergic contact dermatitis presents usually eczematous process or occasionally noneczematous lesions like in this case. We report a case of erythema rnultiforme-like eruptions in a 40-year-old female who presented multiple iris or annular shaped maculopapular eruptions on both hands and forearms after contact of lacquer tree. Being performed with standard patch test screening series, lacquer tree extracts and urushiol, she showed significant reactions to the lacquer tree and urushiol. Histopathologic findings showed both features of erythema multiforme and suh acute contact dermatitis.
Adult ; Dermatitis, Allergic Contact ; Dermatitis, Contact ; Erythema Multiforme* ; Erythema* ; Female ; Forearm ; Hand ; Humans ; Iris ; Lacquer* ; Mass Screening ; Patch Tests ; Trees*

We report herein a case of bowenoid papulosis, which developed on the groin, the shaft of the penis and left parietal area, of scalp in a 31-year-old male. Clinical features present as brown to brown-black papules and verrucous plaques ranging from 2 cm to 12 cm in diameter. Electron microscopic examination of the specimen obtained from our patient fail to reveal viral particles.
Adult ; Genitalia* ; Groin ; Humans ; Male ; Penis ; Rabeprazole ; Scalp ; Virion

Oral medication is one of the most frequent treatment in clinical care, and frequently refused by children. Children's refusal spends unuseful time and require nurses' patience. So this study was attempted to develop token economy program which promote children's medication, and to evaluate its' effect to construct the experimental ground. This study was a quasi experimental study under the nonequivalent control group non-synchronized design. The subjects of this study were 48 children who were aged 3-12 years and admitted pediatric ward because of their respiratory disease. Token economy program was consisted of cartoon record paper with stickers which expresses the better medication is taken the more germs die, and gift was given for back up reinforcer. To evaluate this program, time spent for oral medication was measured six time to both experimental group and control group, and measured the perceived effectiveness of this program by nurses. To determine the effect of the program, the data were analyzed by the SAS 6.12 program with t-test and mean, standard deviation. The results of this study were as follows: 1. In experimental group, time spent for oral medication was significantly shorter than in control group(t=5.24, p=0.0001). Therefore, the hypothesis of this study was strongly accepted. 2. Nurses perceived this program as an effective one(mean=3.125 ~ 3.792). The effectiveness occurred before, during and after medication as well as in parental responses, especially in using verbal dissatisfaction after medication. In conclusion, it was found that the token economy program for admitted children was effective in inducing the children's behavior of oral medication. There was no effectiveness in very highly anxious children. Whereas, it is recommended that this program should not be used for such children until they settle down. If the token economy program was made in various situation with creative thinking, it will be very useful nursing measurement, especially in caring for children. To improve the quality of nursing care, the various programs, which can give joyfulness to stressed patients should be developed.
Child ; Disulfiram ; Humans ; Nursing ; Nursing Care ; Parents ; Thinking ; Token Economy* ; Child Health

BACKGROUND: During the last few years, the in vivo study of the physiological parameters of the skin by non-invasive methods has been considerably developed. So far, there have been some reports on the skin characteristics only in parts, but there has not been any criteria to classify those of normal subjects. OBJECTIVE: The aim of the present study was to investigate the skin characteristics of healthy Korean subjects according to sex and sites using non-invasive methods. METHODS: To determine normal levels of sebum, skin hydration, transepidermal water loss (TEWL), skin elasticity and skin color according to sex, 163 subjects (male; 124, female; 39) were used to investigate 5 different anatomical sites. 6 different instruments were used: The Sebummeter SM 410, Corneometer CM 820, Evaporimeter EP1, Cutometer SEM 474, Chromameter CR-121, and Mexameter MX 16, for evaluating sebum excretion rate, capacitance, TEWL, mechanical property and skin color respectively. RESULTS: Differences were noticed depending on the anatomical sites and sex. Most of the measuring parameters were significantly different according to sites and sex. The values of sebum levels, capacitance and TEWL were higher in the males on the cheek, forehead and crows foot, whereas in the females, higher values were observed on the dorsum of the hand. The skin elasticity varied considerably among the nine-parameters but, for the elastic ratio (R2, R5), the females showed significantly higher values than the males in all sites except the forehead. Skin lightness (L* value) was higher in the females, whereas the males showed lugher values in the category of redness (a* value) and yellowness (b* value). The values of the eqrthema index (EI) and melanin index (MI) were also higher in the males on all sites. Correlations between the skin parameters mentioned above were calculated. A negative, correlation between capacitance and TEWL was observed only on the cheek (male/female, r =-0.2/ r =-0.4, p<0.05). The L* value correlated negatively with MI. Mioreover the values between a* and El also showed sipificant correlations in the male (cheek and dorsum of hand, y =0.2, forehead and crows foot, r =0.3, p<0.05). There were considerably significant correlations between the visual pigmentation score and instrumental skin parameters in the males (visual pigmentation score vs. L* value measured by Chromameter ; cheek/crows foot, r = -0.3/y =-0.4, visual pigmentation score vs. MI by Mexameter ; cheek/crows foot, r =0.2/ r =0.4, viisual winkle score vs. sebum excretion rate measured by Sebumeter ; cheek, r=0.2, visual winkle score vs. elasticity parameters measured by Cutometer ; cheek, R2/R5/R7, r =-0.3/ r =-0.2/ r =-0.3, p<0.05). CONCLUSION: Skin physiological parameters can be evaluated by non-invasive skin bioengineering methods which show quantitative modifications in physiological conditions in relation to sites and sex.
Bioengineering* ; Cheek ; Crows ; Elasticity ; Female ; Foot ; Forehead ; Hand ; Humans ; Male ; Melanins ; Pigmentation ; Sebum ; Skin*

BACKGROUND: Cosmetics are one of the common causes of contact dermatitis and many new cosmetic products are being introduced rapidly into our market. OBJECTIVE: Our purpose was to investigate the as is patch test result by several factors including age, cosmetic product and atopic diseases, and to compare as is patch result with those of standard and cosmetic patch tests. METHODS: The records of 240 patients were reviewed who had been patch tested with their own cosmetics and toiletries with a clinical impression of cosmetic contact dermatitis at the patch clinic of Kangnam St. Mary's Hospital in the period of 1991-1995. RESULTS: Of the 95 patients who were tested with European standard series 54 (56.8%) showed a positive reaction and nickel sulfate was the most common allergen. Eighteen (38.3%) of the 47 patients tested with a cosmetic series revealed a positive reaction and imidazolidinyl urea and dodecyl gallate were the most common allergens. In as is patch test, 99 (41.3%) of the 240 patients showed a positive reaction to 248 (7.3%) of the 3403 cosmetics. Common cosmetic products showing positive reactions were skin care products (26.2%), face make-ups (19.8%), and hair preparations (16.9%). There was no statistically significant difference in the positive reaction rate between atopy and non-atopy patients. The positive correlation rate of as is test with standard and cosmetic series was relatively low. CONCLUSION: Commercial standard patch test series including cosmetic series are not enough to detect causative allergen in cosmetic contact dermatitis. As is patch test should be encouraged to detect new allergens, because many cosmetic ingredients are developed and introduced in market.
Allergens ; Dermatitis, Contact* ; Hair Preparations ; Humans ; Nickel ; Patch Tests* ; Skin Care ; Urea

BACKGROUND: Post-herpetic neuralgia is the most serious one of herpes zoster complications and its incidence becomes higher as the age of the patient increases. Nevertheless, besides considering the age and onset time of treatment, there is no more objective factor estimating the prognosis of post- herpetic neuralgia. OBJECTIVE: The aim of this study is to understand the progression of herpes zoster and estimate the prognosis of post-herpetic neuralgia by practicing electrodiagnostic tests to patients with herpes zoster. METHODS: We evaluated the pain scales in 26 patients with herpes zoster on the first visit and 2 months later. We also performed electrodiagnostic tests, more objective and reproducible methods, including somatosensory evoked potentials and motor nerve conduction studies on both the involved and uninvolved sites of 32 lesions in 26 patients with herpes zoster, and then compared the results with the change of pain scales. RESULTS: 1. The pain category scale and visual analogue scale on the second examination were significantly decreased compared with those on the first examination (P<0.05). 2. Latencies of intercostal somatosensory evoked potentials recorded on scalp and spine were significantly delayed in involved sides compared with those in uninvolved sides (P<0.05). 3. In the latencies and conduction velocities of motor nerve conduction studies, no significant differences were seen between involved sides and uninvolved sides. 4. On the second examinataion, latency differences of somatosensory evoked potentials were significantly improved compared with those on the first examination (P<0.05). 5. Among the various somatosensory evoked potentials parameters, P1 latency difference of cortical somatosensory evoked potentials between involved and uninvolved sides correlated significantly with pain category scale ard visual analogue scale on second examination (r=0.48, P<0.05; r =0.51, P<0.05, respectively). N1 latency difference of spinal somatosensory evoked potentials between involved and uninvolved sides correlated significantly with a visual analoge scale on the first examination and pain category scale on the second examination (r=0.61, P<0.05; r=0.78, P<0.05, respectively). CONCLUSION: Intercostal somatosensory evoked potentials can be a useful and reliable technique to predict the development and severity of post-herpetic neuralgia.
Evoked Potentials, Somatosensory ; Herpes Zoster* ; Humans ; Incidence ; Neural Conduction ; Neuralgia* ; Prognosis ; Scalp ; Spine ; Weights and Measures

This study was carried out to observe the ultrastructure of tongue mast cells in frog, Bombina orientalis. In the light microscopy, mast cells were round, oval, spindle-like and irregular shape and occasionally had one or more tail-like long cytoplasmic processes. Mast cells had many red granules stained with toluidine blue in the cytoplasm. In the electron microscopy, mast cells had membrane-bounded granules and poorly developed organelles. The granules were composed of two parts, low and dense electron density. In high magnification the dense part in the middle region of granule had honey comb-like crystalline structure.
Anura* ; Crystallins ; Cytoplasm ; Honey ; Mast Cells* ; Microscopy ; Microscopy, Electron ; Organelles ; Tolonium Chloride ; Tongue*

No abstract available.
Ectodermal Dysplasia*