1.A Case of Sebaceous Epithelioma.
Sang Soo LEE ; Moo Hyung LEE ; Nack In KIM
Korean Journal of Dermatology 1988;26(4):597-601
Sebaceous epithelioma is an uncommon and primary neoplasm of sebaceous gland. We report herein a case of sebaceous epithelioma in an 85-year-old female. Physical examination showed a solitary, 2.5 x 3.5cm sized, reddish. irregularly surfaced, and well defined tumor on the intercanthal area. Histopathological findings showed tumor parenchyma. romprised of several large nests of three kinds of epithelial cells, mature sebaceous cells, undifferentiated cells arranged in pa1isade fashion at the periphery of a cell nest, and transitional cells showing beginning fatty vacuolizatiorn of the cytoplasm. Electron micocopy revealed immature dark cells, transitional cells, and mature sebaceous cell which showed many scattered foci of sebaceous ditferentiation characterized by intracytoplasmic lipid droplets and glycogen particls.
Aged, 80 and over
;
Carcinoma*
;
Cytoplasm
;
Epithelial Cells
;
Female
;
Glycogen
;
Humans
;
Physical Examination
;
Sebaceous Glands
2.The Measurement of the Segmental Subcutaneous Oxygne Tension for the Determination of Amputation Level
Eun Woo LEE ; Jong Seung LEE ; Moo Hyung CHUNG
The Journal of the Korean Orthopaedic Association 1984;19(1):97-102
No abstract available in English.
Amputation
3.A Case of Pellagra with Psychoneurotic Symptoms and Neurologic Disturbances.
Moo Hyung LEE ; Jai Il YOUN ; Soo Duk LIM
Korean Journal of Dermatology 1981;19(4):567-573
The authors experienced a case of typical pellagra in 45-year old male. He has been a heavy alcoholic history about 30 years duratian. Well-marginated erythematous created scaly patches, hyperpigmentation and fissures developed on both forearms and both ear lobes, both periorbicular areas, and Casals and klace on the aa0erior neck repeatedly. The skin leaions were aggravated in summers, improving a little in winters from 3 years ago. The psychoneurotic symptoms, neurologic disturbances, and GI troubles accompanied the skin lesions. Diagnosis was made by the characteristic clinical findings. He was treated with nicotinamide and vitamin B complex, and most of symptoms improved much. Authors reported the case and reviewed the literatures.
Alcoholics
;
Diagnosis
;
Ear
;
Forearm
;
Humans
;
Hyperpigmentation
;
Male
;
Middle Aged
;
Neck
;
Neurologic Manifestations
;
Niacinamide
;
Pellagra*
;
Skin
;
Vitamin B Complex
4.Primary Cutaneous Meningioma arising from the Scalp: A case report.
Sug Hyung LEE ; Seok Jin GANG ; Sun Moo KIM
Korean Journal of Pathology 1993;27(2):181-183
Primary cutaneous meningiomas are extremely rare tumors found in the cutis or subcutis, and generally have a benign course. The tend to be located on the scalp, face, neck. or paravertebral area. The primary cutaneous meningioma bears similarities to developmental defects and probably originates from arachnoid cell rests in the skin, although diverse groups of cutaneous meningiomas seem to arise from several different sources. A case of primary cutaneous meningioma occuring in the scalp of left parietal area of a 27-year-old female is presented. Clinically the lesion appeared as indolent, slow growing cutaneous mass and has no connection with underlying brain tissue, as determined by examination of the roentgenographs. The definite diagnosis was made after pathological examination. Microscopically the tumor is composed of sheets and nests of meningothelial cells. Immunohistochemical and electron microscopic studies reveal the typical findings of meningioma.
Female
;
Humans
;
Meningioma
5.A Case of Familiar Benign Chronic Pemphigus.
Nack In KIM ; Choon Bong LEE ; Moo HYUNG ; Choong Rim HAW
Korean Journal of Dermatology 1987;25(5):716-721
A 25-year-old man with familial benign chronic pemphigus presented with a one-year history of a localized pruritic recurrent eruption on his perianal area, Physical examination showed moist, macerated, fissured and scaly patches on erythematous base, A biopsy specimen showed extensive intraepidermal separation containing acantholytic cells. Electron microscopic observation showed widened intercellular space, detachment of the tonofilaments from the desmosomes, and subsequent concentration of the tono filaments around the nucleus. Microvilli were elorigated, thinned and branehed. 1)esmosomes were reduced in number. This case is unique in its clinical location, showing no family tendency.
Adult
;
Biopsy
;
Desmosomes
;
Extracellular Space
;
Humans
;
Intermediate Filaments
;
Microvilli
;
Pemphigus, Benign Familial*
;
Physical Examination
6.The Measurement of the Soft Tissue Pressure beneath a Tourniquet in the Arm
Eun Woo LEE ; Byung Woo AHN ; Moo Hyung CHUNG
The Journal of the Korean Orthopaedic Association 1985;20(3):385-389
The use of a pneumatic tourniquet is potentially associated with injury to underlying muscles, vessels, and nerves if excessive pressure occurs beneath the toumiquet. In order to minimize the risk of soft tissue injury, the lowest tourniquet pressure that maintains a bloodless operative field should be used. A clinical study was undertaken to evaluate the pneumatic tourniquet setting required for adequate hemostasis in upper extremity surgery. From March to September in 1984, the subcutaneous soft tissue pressure of the 20 upper extremities beneath a pneumatic toumiquet in the arm were measured directly and the following results were obtained. 1. The underlying subcutaneous soft tissue pressure was not affected by adult, age, arm circumference, and blood pressure of normal range. 2. The underlying subcutaneous soft tissue pressure showed direct correlation with the tourniquet pressure respectively. 3. A tourniquet preasure of more than 250 mmHg was not rarely required in a normotensive individual.
Adult
;
Arm
;
Blood Pressure
;
Clinical Study
;
Hemostasis
;
Humans
;
Muscles
;
Reference Values
;
Soft Tissue Injuries
;
Tourniquets
;
Upper Extremity
7.Morphology and Function of Testis in Growth Deprived Mature and Immature Male Rats.
Hak Ryong CHOI ; Soo Hyung LEE ; Moo Sang LEE ; Jin Moo LEE
Korean Journal of Urology 1994;35(4):357-364
Growth hormone(GH) plays a major role in growth and its effects are mainly mediated by insulin like growth factor-I ( IGF-I). However the role of GH in the regulation of testicular function especially in spermatogenesis is still under debate. Though there were several studies using GH-deficient mutant mice, results are conflicting. Furthermore they are not proper to find out any exact role of GH in normal adults. We have therefore used somatostatin analogue (Sandostatin) for 1 week to block the effect of GH and it's mediator IGF-I, in mature and immature Sprague-Dawley male rats. In immature rats the delayed maturation was recovered after ceasing somatostatin in several weeks and the testicular parameters became normal after maturation. Post-pubertal rats showed diminished spermatogenesis especially in the number of pachytene spermatocytes and round spermatids of stage VII. These results seems to be associated with decreased systemic IGF-I. But the Leydig cell function in other words, testosterone production, remained normal. Somatostatin administered Leydig cells showed strong positive reactions like normal control on IGF-I immunohistochemical stain. We concluded that GH mediated IGF-I plays a major role in spermatogenesis especially on pachytene spermatocytes of post-pubertal male rats and there are GH independent IGF-I actions in Leydig cells.
Adult
;
Animals
;
Humans
;
Insulin
;
Insulin-Like Growth Factor I
;
Leydig Cells
;
Male*
;
Mice
;
Rats*
;
Rats, Sprague-Dawley
;
Somatostatin
;
Spermatids
;
Spermatocytes
;
Spermatogenesis
;
Testis*
;
Testosterone
8.Two Cases of Keratosis Palmaris et Plantaris.
Seung Hun LEE ; Min Geol LEE ; Moo Yon CHO ; Hyung Joo KIM ; Won Soo LEE
Korean Journal of Dermatology 1988;26(3):419-425
We reviewed two cases of keratosis punctata palmaris et plantaris(KPP) and the scanning electron microscopic findings(SEM). The skin lesions of KPP are multiple, hyperkeratotic on the palms and soles with central pitting. There was no subjective symptoms. The histologic findigs revea,l marked hyperkeratosis, hypergranulosis, and acanthosis with depression of the underlying malpighian layers. The SEM findings reveal one hyperkeratoic plug on punctate lesion(case I ) and three hyperkeratotic plugs on depression of the malpighian layer(case ll ).
Depression
;
Keratoderma, Palmoplantar*
;
Keratosis*
;
Skin
9.Carcinosarcoma of the Esophagus: A report of case.
Sug Hyung LEE ; Won Sang PARK ; Young Jin CHOI ; An Hee LEE ; Sun Moo KIM
Korean Journal of Pathology 1992;26(2):191-196
Carcinosarcoma of the esophagus is a rare neoplasm composed of both carcinoma and spindle sarcomatous area. Usually the carcinoma component is a squamous cell carcinoma but rarely adenocarcinoma or undifferentiated carcinoma is found. The histogenesis of the sarcomatous component is still unknown. A case of ulcerated polypoid lesion with a stalk in esophagus was reported. Microscopically it was composed of spindle shaped cells interminled with squamous cell carcinoma and small cell carcinoma nests. No distinct transition between spindle shaped cells and carcinoma are was observed. Immunoreactivity to cytokeratin was observed in both carcinomatous and spindle cell component, but electron microscopic examination failed to demonstrated desmosome or tonofilaments in spindle cells. Undifferentiated small cell nests were reactive to neuron specific enolase and contained membrane bounded secretory granule in electron microscopy.
Adenocarcinoma
10.Therapeutic Effects of Norfloxacin(Neutam-400.
Sung Suk HAN ; Young Yo PARK ; Hyung Ki CHOI ; Moo Sang LEE ; Jin Mee LEE
Korean Journal of Urology 1985;26(3):237-242
Norfloxacin is a new broad spectrum of antibacterial activity against both Gram-positive and Gram. negative bacteria. After oral administration of Norfloxacin, it produces high concentrations in the urine, so it has the excellent effect for the treatment of urinary tract infection. Norfloxacin was studied with respect to clinical effect in 115 patients with the urinary tract infection and the following results were obtained. 1. Excellent efficacy was 53% and efficacy rate was 90% in upper urinary tract infection(UTI). Efficacy rate for 20 patients with upper UTI without the underlying disease was 100%, and in 29 patients with underlying disease efficacy rate was 83%. 2. In upper UTI resistant for other antibiotics, efficacy rate was 78%. 3. In lower UTI excellent efficacy rate was 36% and efficacy rate was 71%. In gonococcal urethritis excellent efficacy rate was 76% and efficacy rate was 88%. 4. Eliminated rate of bacteria on culture findings were E. coli 93%, pseudononas 89%, proteus 100%, klebsiella 80%, gonococcus 88% and staphylococcus 80%. 5. Mild side effects such as epigastric pain, nausea, dizziness and itching sensation were seen in 5 cases. We consider Neutam-400 is one of the most effective agents in urinary tract infection.
Administration, Oral
;
Anti-Bacterial Agents
;
Bacteria
;
Dizziness
;
Humans
;
Klebsiella
;
Nausea
;
Neisseria gonorrhoeae
;
Norfloxacin
;
Proteus
;
Pruritus
;
Sensation
;
Staphylococcus
;
Urethritis
;
Urinary Tract Infections*
;
Urinary Tract*