1.No title available in English.
Hyung Woo PARK ; In Sok YEO ; Min Seok JEONG ; In Hyuk CHUNG
Korean Journal of Physical Anthropology 1990;3(1):41-46
No abstract available.
2.Multiple Trichoepithelioma Associated with Milia.
Young Min PARK ; Hyung Ok KIM ; Chung Won KIM
Annals of Dermatology 1998;10(3):172-174
We present a case of multiple trichoepithelioma associated with milia. A 12-year-old girl developed symmetrically distributed, numerous, skin-colored papules on her face, some of which were studded with milia-like whitish materials. Histopathological findings of these lesions revealed the typical findings of trichoepitheliomas with overlying milia in the upper dermis.
Child
;
Dermis
;
Female
;
Humans
3.Occupational Contact Urticaria Syndrome Induced by Cefotiam Dihydrochloride in a Nurse.
Hye Jeong CHOI ; Ji Youn SONG ; Young Min PARK ; Chung Won KIM ; Hyung Ok KIM
Annals of Dermatology 2003;15(3):113-115
We herein report a case of occupational contact urticaria syndrome induced by cefotiam di-hydrochloride in a nurse. She had generalized pruritic wheals accompanied by palpitations and tachypnea during the preparation of cefotiam solution. A scratch patch test with cefotiam di-hydrochloride, a major component of cefotiam ingredient showed multiple erythema and wheals within 5 minutes, accompanied by palpitations and tachypnea. No delayed type reaction was observed. Based on her clinical history and scratch test result, we diagnosed her condition as contact urticaria syndrome caused by cefotiam.
Cefotiam*
;
Erythema
;
Patch Tests
;
Tachypnea
;
Urticaria*
4.A Case of Connubial Contact Dermatitis due to Rhus.
Jung Min CHOI ; Jeong Deok LEE ; Hyung Ok KIM ; Chung Won KIM
Korean Journal of Dermatology 1998;36(3):469-472
Allergic contact dermatitis that is attributable to contact with environmental sensitizers boine by a second individual, especially in marital or sexual relationships, has been described as connubial contact dermatitis. Severely pruritic multiple erythematous plaques, vesicles and bullae in a 35-year-old woman occurred on the face, posterior area of the neck, breasts, buttock, and both upper arms. No direct contact to allergens was obtained. However her husband had eaten some cooked sprouts from a lacquer tree for lunch at a restaurant the day before her eruption, then he caressed her that night. A patch test with extracts of lacquer tree in ethanol(2%), crushed extracts of lacquer tree (as is), and urushiol(0.002% pet.) on the patients back showed strong positive reactions.
Adult
;
Allergens
;
Arm
;
Breast
;
Buttocks
;
Dermatitis, Allergic Contact
;
Dermatitis, Contact*
;
Female
;
Humans
;
Lacquer
;
Lunch
;
Neck
;
Patch Tests
;
Restaurants
;
Rhus*
;
Spouses
;
Trees
5.The Inhibition of Stress-Induced c-fos Expression by Superior Cervical Ganglion Block in Rat Brain.
Hyun Ju JUNG ; Chong Min PARK ; Dong Suk CHUNG ; Myung Ja AHN ; Hyung Jin BYUN
Korean Journal of Anesthesiology 1997;33(6):1029-1036
BACKGROUND: Using c-fos expression one of the immediate early gene, as a marker of altered neuronal response, we investigated the effect of superior cervical ganglion block (SCGB) exhibiting the same effect of SGB of human on the activity of several brain regions which are considered as located on autonomic neural pathway and neuroendocrine axis in rat. METHOD: The 48 Sprague-Dawley strain rats were divided into 4 groups, as saline/stress (control) group, SCGB/stress (tested) group, saline group, SCGB group. Superior cervical ganglion block was conducted in the SCGB/stress group and SCGB group while saline/stress and saline group were sham operated. After then restraint stress was imposed on the animals of SCGB/stress group and saline/stress group. And 2 hour after injection (saline, SCGB group) or restraint stress (saline/stress, SCGB/stress group), c-fos protein (Fos) was localized by immunocytochemistry. RESULTS: Much stronger Fos immunoreactivity was induced in the several brain region of control group rats compared to other three groups and the numbers of Fos positive cell count of tested group were significantly decreased in paraventricular hypothalamic nucleus (p<0.01), A5 (p<0.01), raphe pallidus (p<0.05), nucleus tractus solitaius (p<0.01) compared to control group. CONCLUSION: This study demonstrate that superior cervical ganglion block attenuates stress induced neuronal activities of paraventricular hypothalamic nucleus, A5, raphe pallidus, nucleus tractus solitarius.
Animals
;
Axis, Cervical Vertebra
;
Brain*
;
Cell Count
;
Genes, vif
;
Humans
;
Immunohistochemistry
;
Neural Pathways
;
Neurons
;
Paraventricular Hypothalamic Nucleus
;
Rats*
;
Rats, Sprague-Dawley
;
Solitary Nucleus
;
Superior Cervical Ganglion*
6.A Case of Malignant Acanthosis Nigricans Associated with Gastric Adenocarcinoma.
Hyung Geun PARK ; Seong Min PARK ; Doo Chan MOON ; Kyung Sool KWON ; Tae Ahn CHUNG
Korean Journal of Dermatology 1989;27(3):316-319
A 51-year-old female had disseminated, symmetrically distributed, brownish black pigmentation and papillary hypertrophy on the intertriginous and flexural areas for 6 months, and gastric adenocarcinoma was confirmed during the evaluation of internal malignancy, The cutaneous finding of acanthosis nigricans was a significant cutaneous marker of internal malignancy in this case.
Acanthosis Nigricans*
;
Adenocarcinoma*
;
Female
;
Humans
;
Hypertrophy
;
Middle Aged
;
Pigmentation
7.Two cases of cutis verticis gyrata due to cerebriform intradermal nevus.
Young Min PARK ; Dong Won LEE ; Jin Woo KIM ; Hyung Ok KIM ; Chung Won KIM
Korean Journal of Dermatology 1993;31(2):258-263
Cutis verticis gyrata(CVG) is an unusual conformation of the scap characterized by the presence of folds and furrows due to thickening of the corium and the subutlneous tissue. In sccordance with etiological factor and associated findings, CVG occurs as primarary disease or secondary to a variety of local or systemic diseases. Cerebriform intradermal nevus(CIN) is a cause of CVG that can usually be recognized clinically and for a certainty histologically. We report two cases of CVG due to CIN. Not only did they have CVG due to CIN on the scalp, but also they had associated congenital nevi on the face and whole boispy, respectively.
Dermis
;
Nevus
;
Nevus, Intradermal*
;
Scalp
8.Clinical application of human embryonic stem cells.
Journal of the Korean Medical Association 2011;54(5):454-461
Recent advances in stem cell biology, including the development of optimized cell type-specific culture systems, and the broader understandings of biochemical and molecular signals involved in cell self-renewal and differentiation have brought cell-based therapy closer to practical application. As of now, at least 250 adult stem cell therapies are being used or tested in clinical situations. Stem cells have two important properties that distinguish them from other types of cells; they can both proliferate without changing their phenotypes indefinitely, and they also can differentiate into one or more new kinds of cells depending on their culture conditions. Thus, stem cell therapy could be most effective for treating the diseases that are marked by the loss of cells. The typical examples are Parkinson's disease, Alzheimer's disease, diabetes, heart failure, blindness, spinal cord injury, and stroke. Additionally, stem cell derivatives can be used in drug discovery as well. In the last decade, various types of stem cells have been identified from preimplantation stage embryos, fetuses, placentas, and adult tissues. Moreover, it is now almost a common practice to produce induced pluripotent stem (iPS) cells from various adult somatic cells using only a few defined factors. Thus, it is feasible that patient-specific stem cells will be generated with less controversy in the near future. However, human embryonic stem (ES) cells firmly remain "the gold standard" because of their greatest potential to become any type of cell in the body. The vast knowledge obtained from human ES cell research in the past decade has made cell-based therapy more promising than ever. Even the recent establishment of iPS cell technology is the culmination of human ES cells research. In our laboratory, interesting human cardiovascular cells including endothelial precursor cells and beating myocardiac cells, artificial blood cells, and retinal pigment epithelial cells were successfully differentiated and their therapeutic potential was confirmed after cell transplantation into animal models. Thus, here, the current research status of human embryonic stem cell-based therapy will be introduced and the future directions of stem cell applications in clinical trials will be discussed.
Adult
;
Adult Stem Cells
;
Alzheimer Disease
;
Artificial Cells
;
Biology
;
Blindness
;
Blood Cells
;
Cell Transplantation
;
Drug Discovery
;
Embryonic Stem Cells
;
Embryonic Structures
;
Epithelial Cells
;
Fetus
;
Heart Failure
;
Humans
;
Induced Pluripotent Stem Cells
;
Models, Animal
;
Parkinson Disease
;
Phenotype
;
Placenta
;
Retinaldehyde
;
Spinal Cord Injuries
;
Stem Cells
;
Stroke
;
Transplants
9.Three cases of unilateral localized hypertrichosis on the face.
Young Min PARK ; Jin Woo KIM ; Hyung Ok KIM ; Chung Won KIM
Korean Journal of Dermatology 1992;30(4):551-557
Hypertrichosis is an overgrowth of hair not localized to the anclro en dependent areas of the skin. It may be congenital or acquired, localized or generalized localized hypertrichosis may occur in some types of pigrnentary nevi, chronic inflammation or irration, topical application of androgen or steroid, & localized myxedema. We report herein three i:ases of unilateral localized hypertrichosis with or without a brownish hyperpigmented patch developing on the face of a male adol scent. There are no known cau:,es of localized hyper trichosis. Histopath logically, it is characterized by increased melaniii pigment in the basal layer of the epidermis & enlarged hair follicles containing coarser liair. Electron microscopic findings show normal size & number of melanosomes in both mela nocytes & keratinocytes. Our cases differ frorn BecLers nevus in both clinical & histopatholcgic characteristics.
Epidermis
;
Hair
;
Hair Follicle
;
Humans
;
Hypertrichosis*
;
Inflammation
;
Keratinocytes
;
Logic
;
Male
;
Melanosomes
;
Myxedema
;
Nevus
;
Skin
10.Sequence analysis of polyhedrin gene promoter and construction of an expression vector of hyphantria cunea nuclear polyhedrosis virus.
Kap Joo PARK ; Bong Joo KANG ; Hye Kyung CHUNG ; Bon Hong MIN ; Hyung Hoan LEE
Journal of the Korean Society of Virology 1993;23(2):141-151
No abstract available.
Nucleopolyhedrovirus*
;
Sequence Analysis*