1.Production of monoclona antibody to infectious bursal disease virus as a diagnostic methods.
Hyung Kwan JANG ; Jai Hong KIM ; Chang Seon SONG ; Soon Jae KIM ; Tae Jong KIM
Journal of the Korean Society of Virology 1993;23(2):171-182
No abstract available.
Infectious bursal disease virus*
2.Posterior Cervical Inclinatory Foraminotomy for Spondylotic Radiculopathy Preliminary.
Jae Chil CHANG ; Hyung Ki PARK ; Soon Kwan CHOI
Journal of Korean Neurosurgical Society 2011;49(5):308-313
Posterior cervical foraminotomy is an attractive therapeutic option in selected cases of cervical radiculopathy that maintains cervical range of motion and minimize adjacent-segment degeneration. The focus of this procedure is to preserve as much of the facet as possible with decompression. Posterior cervical inclinatory foraminotomy (PCIF) is a new technique developed to offer excellent results by inclinatory decompression with minimal facet resection. The highlight of our PCIF technique is the use of inclinatory drilling out for preserving more of facet joint. The operative indications are radiculopathy from cervical foraminal stenosis (single or multilevel) with persistent or recurrent root symptoms. The PCIFs were performed between April 2007 and December 2009 on 26 male and 8 female patients with a total of 55 spinal levels. Complete and partial improvement in radiculopathic pain were seen in 26 patients (76%), and 8 patients (24%), respectively, with preserving more of facet joint. We believe that PCIF allows for preserving more of the facet joint and capsule when decompressing cervical foraminal stenosis due to spondylosis. We suggest that our PCIF technique can be an effective alternative surgical approach in the management of cervical spondylotic radiculopathy.
Constriction, Pathologic
;
Decompression
;
Female
;
Foraminotomy
;
Humans
;
Male
;
Mandrillus
;
Radiculopathy
;
Range of Motion, Articular
;
Spondylosis
;
Zygapophyseal Joint
3.Quantitative Measurement of Current Perception Threshold in Carpal Tunnel Syndrome.
Yoon Kyoo KANG ; Kwan Sik SEO ; Eun Mi PARK ; Chang Hyung LEE
Journal of the Korean Academy of Rehabilitation Medicine 2000;24(4):710-717
OBJECTIVE: To compare current perception threshold with nerve conduction study, we measured current perception threshold (CPT) in healthy control and patients with carpal tunnel syndrome (CTS). METHOD: Twenty control subjects and twenty patients with CTS were included. Latency and amplitude of median and ulnar motor and sensory nerves were measured. The sensory current perception threshold was measured at the distal interphalangeal joint of third and fifth fingers and the palm with electrical current of 5 Hz, 250 Hz, and 2,000 Hz in frequency. We compared the results of the nerve conduction study with the data of the CPT. RESULTS: We found that measuring of the sensory threshold might detect carpal tunnel syndrome, especially with 2,000 Hz and 250 Hz stimulation and that CPT data correlated to sensory latency and amplitude of the median nerve. CONCLUSION: The sensory threshold test might be useful for diagnosis and follow up test in carpal tunnel syndrome.
Carpal Tunnel Syndrome*
;
Diagnosis
;
Fingers
;
Humans
;
Joints
;
Median Nerve
;
Neural Conduction
;
Sensory Thresholds
4.A Case of Severe Gastric Ulcer Bleeding after Exchange for Replacement Balloon Gastrostomy Tube in Percutaneous Endoscopic Gastrostomy.
Hyung Keun CHUNG ; Young Kwan KIM ; Seok Ho DONG ; Hyo Jong KIM ; Byung Ho KIM ; Jung Il LEE ; Young Woon CHANG ; Rin CHANG
Korean Journal of Gastrointestinal Endoscopy 1993;13(2):371-374
PEG is a simple, safe and rapid method for the placement of feeding gastrostomy tube because of its low morbidity and mortality. Also, exchange of gastrostomy tube can be easily performed because several types of exchange tube, suich as replacement balloon gastrostomy tube are available. But, less has been known about complications of exchange tube. The authors experienced a case of severe gastric ulcer bleeding in seventy one years old male patient who had been suffered from melena after exchange of old PEG tube for replacement balloon gastrostomy tube. Gastroscopy showed bleeding from acute, large and deep ulcer on the body of stomach, and replacement tube tip directed to the center of ulcer. Bleeding was thought to be caused by gastric ulcer due to replacement balloon gastrostomy tube, After removal of tube and conservative management with H2 receptor antagonist, bleeding ceased
Gastroscopy
;
Gastrostomy*
;
Hemorrhage*
;
Humans
;
Male
;
Melena
;
Mortality
;
Stomach
;
Stomach Ulcer*
;
Ulcer
5.Comparison of Fast FLAIR and Echo-Planar FLAIR Imaging in Cere b ral Lesions.
Kyung Jin KANG ; Myung Kwan LIM ; Choong Kun HA ; Young Kuk CHO ; Chang Keun LEE ; Hyung Jin KIM ; Chang Hae SUH
Journal of the Korean Radiological Society 1999;41(3):441-446
PURPOSE: To evaluate the usefulness of echo-planar FLAIR imaging in various cerebral lesions as compared with fast FLAIR imaging. MATERIALS AND METHODS: We obtained consecutive fast FLAIR and echo-planar FLAIR images in 33patients in whom MR imaging had revealed ischemic infarction (n=11), acute infarction (n=5), brain tumor (n=3), other conditions (n=3) or no abnormality (n=11). On both sets of images, percentage contrast and contrast to noise ratio (CNR) were calculated for white matter-gray matter and white matter-lesion. RESILTS: White matter-gray matter percentage contrast and CNR were lower on echo-planar FLAIR imaging than on fast FLAIR imaging (percentage contrast, 19 +/- 2 % vs 28 +/- 3 %, CNR, 2.77 +/- 0. 5 vs 4.86 +/- 0.7). White matter-lesion percentage contrast on echo-planar FLAIR imaging was similar to or greater than that on fast FLAIR imaging; 75 +/- 12 % vs 45 +/- 11 % in ischemic infarction, 80 +/- 12 % vs 78 +/- 11% in acute infarction, and 121 +/- 25 % vs 102 +/- 15 % for tumors. White matter-lesion CNR was similar on both sets of images: 8.3 +/- 0.9 vs 7.9 +/- 0.8 in ischemic infarction, 11 +/- 1.5 vs 9.5 +/- 1.2 in acute infarction, and 24 +/- 4 vs 27 +/- 3 for tumors. Due to high susceptibility to magnetization, echo-planar FLAIR imaging showed image degradation at the interface of the paranasal sinus and adjacent to the temporal bone. CONCLUSION: Echo-planar FLAIR imaging may be a useful pulse sequence in the diagnosis of various cerebral lesions.
Brain Neoplasms
;
Diagnosis
;
Infarction
;
Magnetic Resonance Imaging
;
Noise
;
Temporal Bone
6.Relationship Between Subjective Memory Complaints and Cognition in the Elderly.
Ki Jung CHANG ; Kang Soo LEE ; Hyun Jung KIM ; Hae Kwan CHEONG ; Byoung Hoon OH ; Chang Hyung HONG
Journal of Korean Geriatric Psychiatry 2009;13(2):91-96
OBJECTIVES: We aimed to investigate the relationship between subjective memory complaints and cognition in the elderly. METHODS: Data obtained from 1,496 subjects (510 men and 986 women) aged above 60 years was analyzed from the Gwangju Dementia and Mild Cognitive Impairment Study (GDEMCIS). All subjects completed the study questionnaire including demographic characteristics, history of current and past illnesses, drug history, Korean version-Mini Mental State Examination (K-MMSE), and Short Form Korean version of Geriatric depression scale (SGDS-K). Subjective memory complaints were defined in two different ways; worse than others (SMC-O) and worse than one's past (SMC-P). RESULTS: On analysis of covariance, there was significant difference of estimated marginal means of K-MMSE score among five SMC-P groups (much improve:18.0, little improve:21.3, not changed:21.2, little worse:21.1, much worse:20.2) after adjusting age, sex, educational level and depression (F=9.63, df=4, p<0.0001, adjusted R2=0.375). There was significant difference of estimated marginal means of K-MMSE score among three SMC-O groups (below peer's average:20.4, peer's average:20.9, above peer's average:21.8) after adjusting age, sex, educational level and depression (F=4.89, df=2, p=0.043, adjusted R2=0.0.361). CONCLUSION: These results suggest that subjective memory complaints may be an indicator of objective cognitive impairment in the elderly.
Aged
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Cognition
;
Dementia
;
Depression
;
Humans
;
Male
;
Memory
;
Mild Cognitive Impairment
;
Surveys and Questionnaires
7.Time trends in acute pancreatitis.
Bai Young KIM ; Hyo Jong KIM ; Hyung Keun CHUNG ; Young Kwan KIM ; Seok Ho DONG ; Byung Ho KIM ; Jung Il LEE ; Young Woon CHANG ; Rin CHANG
Korean Journal of Medicine 1993;45(5):597-605
No abstract available.
Pancreatitis*
8.Comparison Study between Dobutamine Stress Echocardiography Using Real-Time Three Dimensional and Two Dimensional Echocardiography for Diagnosis of Coronary Artery Disease : Dobutamine Stress Echocardiography Using Real-Time Three Dimensional Echocardiogr.
Gi Chang KIM ; Chang Kun LEE ; In Sun AHN ; Woong Gil CHOI ; Yun Ah CHOI ; Young Sam KIM ; Dae Hyeok KIM ; Keum Soo PARK ; Woo Hyung LEE ; Jun KWAN
Korean Circulation Journal 2006;36(11):737-743
BACKGROUND AND OBJECTIVES: Dobutamine stress echocardiography (DSE) with 2D echocardiography (2DE) is one of the time-consuming procedures in the diagnosis of coronary artery disease (CAD). Moreover, the accuracy of DSE with 2DE depends on the operator's skill or bias during the image acquisition. This study was conducted to determine the feasibility and accuracy of DSE with real-time 3D echocardiography (RT3DE) for the diagnosis of CAD. SUBJECT AND METHODS: 62 patients (RT3DE: 36, 2DE: 26), suspected of angina pectoris and post-revascularization ischemia, underwent DSE and coronary angiography (CAG). Image acquisition was performed at the baseline, and at 4 times during the dobutamine infusion and recovery stages. The procedure time (from the baseline to the end of the peak dose stage) was recorded. Off-line analyses of the volumetric images acquired with RT3DE were performed using 3D computer software (TomTec, Co.). Digitized quad-screen images acquired with 2DE were analyzed using the 2DE review system (ProSolv 4.0). >50% luminal diameter stenosis of any coronary artery on CAG was defined as significant coronary artery stenosis. RESULTS: The procedure time of DSE with RT3DE was significantly shorter than that of DSE with 2DE (25+/-4 vs. 37+/-4 mins, p<0.001). There was no significant difference in the sensitivity (p>0.05) or specificity (p>0.05) between the two procedures. CONCLUSION: DSE with RT3DE seems to be a feasible and less time consuming diagnostic procedure, probably providing comparable sensitivity and specificity for the detection of coronary artery stenosis, than DSE with 2DE.
Angina Pectoris
;
Bias (Epidemiology)
;
Constriction, Pathologic
;
Coronary Angiography
;
Coronary Artery Disease*
;
Coronary Stenosis
;
Coronary Vessels*
;
Diagnosis*
;
Dobutamine*
;
Echocardiography*
;
Echocardiography, Stress*
;
Echocardiography, Three-Dimensional*
;
Humans
;
Ischemia
;
Phenobarbital
;
Sensitivity and Specificity
9.Impact of Afterload on the Assessment of Severity of Aortic Stenosis.
Sung A CHANG ; Hyung Kwan KIM ; Dae Won SOHN
Journal of Cardiovascular Ultrasound 2012;20(2):79-84
BACKGROUND: Aortic stenosis (AS) is increasingly diagnosed in current aging society. Echocardiography is the most important tool in the assessment of AS and its severity. However, load-dependency of Doppler measurement could affect the accuracy of AS severity assessment. We tried to evaluate the impact of afterload on the assessment of AS severity by modification of afterload using pneumatic compression (Pcom). METHODS: Forty patients diagnosed as moderate or severe AS [effective orifice area of aortic valve (EOAAV) by continuity equation of < 1.5 cm2] were consecutively enrolled. Patients with severely uncontrolled hypertension, severe left ventricular (LV) dysfunction, and other significant valve disease were excluded. Comprehensive echocardiography was performed at baseline to assess AS severity. Then, pneumatic compression of the lower extremities by 100 mmHg was applied to increase LV afterload. After 3 minutes, echocardiography was repeated to assess AS severity. RESULTS: Mean blood pressure was significantly increased under Pcom (p < 0.001), while heart rate remained unchanged. Peak aortic valve velocity (Vmax) was slightly, but significantly decreased under Pcom (p = 0.03). However, Doppler velocity index and EOAAV by continuity equation were not affected by Pcom. CONCLUSION: AS severity assessment by echocardiography was not dependent on the change of LV afterload imposed by Pcom. AV Vmax was slightly decreased with LV afterload increment, but these changes were too small to alter treatment plan of AS patients. EOAAV and Doppler velocity index are more stable parameters for AS severity assessment.
Aging
;
Aortic Valve
;
Aortic Valve Stenosis
;
Blood Pressure
;
Echocardiography
;
Heart Rate
;
Humans
;
Hypertension
;
Lower Extremity
10.The Analysis of Pathogenesis in the Hypertensive Encephalopathy using Diffusion-Weighted MR Imaging.
Dong Jae SHIM ; Myung Kwan LIM ; Hyung Jin KIM ; Young Kook CHO ; Chang Hae SUH
Journal of the Korean Radiological Society 2001;45(1):1-7
PURPOSE: To investigate the nature of edematous lesions seen on MR images during acute episodes of hypertensive encephalopathy(HTE) with particular attention to the findings of diffusion-weighted imaging (DWI). MATERIALS AND METHODS: A total of 17 MR examinations in fourteen patients with hypertensive encephalopathy were performed. The diagnoses were idiopathic HTE in eight cases, eclampsia in three, and cyclosporin-induced HTE in three. The apparent diffusion coefficients(ADCs) of edematous lesions and normal white matter revealed by DWI were assessed and compared, and the changes observed at follow-up MR imaging were analysed. RESULTS: DWI obtained within one week of the appearance of acute neurological symptoms revealed the edema as iso-intense in all patients with eclampsia and cyclosporin-induced HTE, and in five of eight patients with idiopathic HTE. In the other three patients with idiopathic HTE, DWI demonstrated slightly hyperintense edema. The ADCs of edematous lesion in patients with idiopathic HTE, eclampsia and cyclosporin-induced HTE were 1.21 +/-0.34, 1.08 +/-0.28, and 1.28 +/-0.22 mm 2 /ms, respectively, while for normal white matter the corresponding figures were 0.77 +/-0.25, 0.71 +/-0.22, and 0.68 +/-0.27mm 2 /ms The differences in ADCs between edema and normal white matter were thus significantly different between the three patient groups (p<0.05), while the ADCs of edematous lesions showed no sisgnificant variation between these groups (p<0.05). Follow-up MRI revealed that in three cases, edematous lesions were reversible and there were no residual signal changes. CONCLUSION: Vasogenic rather than cytotoxic edema is present during the acute stage of HTE.
Diagnosis
;
Diffusion
;
Eclampsia
;
Edema
;
Female
;
Follow-Up Studies
;
Humans
;
Hypertensive Encephalopathy*
;
Magnetic Resonance Imaging*
;
Pregnancy