1.Effect of Mechanical Stress on the Proliferation and Expression of Cell Cycle Regulators in Human Periodontal Ligament Cells.
Hyung Keun YOU ; Hyung Shik SHIN ; Gene LEE ; Byung Moo MIN
The Journal of the Korean Academy of Periodontology 1999;29(3):593-605
No abstract available.
Cell Cycle*
;
Humans*
;
Periodontal Ligament*
;
Stress, Mechanical*
2.A case of intracranial arterial thrombosis in nephrotic syndrome.
Moon Gyoo KANG ; Hee Young CHO ; Hyung Kug RYU ; Kyung Min LEE ; Hyo Keun BAE
Korean Journal of Nephrology 1991;10(2):224-227
No abstract available.
Nephrotic Syndrome*
;
Thrombosis*
3.A Case of Pregnancy Using Recombinant Follicle Stimulating Hormone and Gonadotropin Releasing Hormone Antagonist.
Yoon Sung NAM ; Nam Keun KIM ; Eun Kyung KIM ; Hyung Min CHUNG ; Kwang Yul CHA
Korean Journal of Fertility and Sterility 2001;28(1):73-77
OBJECTIVE: To report the pregnancy which was made by in vitro fertilization using recombinant follicle stimulating hormone and gonadotropin releasing hormone antagonist. MATERIAL AND METHOD: Case report. RESULTS: Six oocytes were retrieved and all were fertilized by intracytoplasmic sperm injection. Six embryos were transferred and the pregnancy was confirmed. CONCLUSION: It is envisaged that the availability of recombinant gonadotropins and gonadotropin releasing hormone antagonists will ultimately lead to shorter, cheaper and safer treatments, using reduced dosages.
Pregnancy
;
Female
;
Humans
4.Progressive Multifocal Leukoencephalopathy in the Immunocompromised Patients - 3 Cases Report.
Min Keun SHIM ; Jo Heon KIM ; Chang Soo PARK ; Hyung Seok KIM ; Yoo Duk CHOI ; Min Cheol LEE
Korean Journal of Pathology 2007;41(5):358-361
Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease resulting from infection of oligodendrocytes with JC virus. PML was a rare disease, but nowadays not uncommon as AIDS prevailed. Histopathologic features of the affected lesion shows infiltrations of foamy macrophages and hyperchromatic, pleomorphic, reactive astrocytes that may raise the suspicion of a brain tumor. We recently met with 3 cases of PML. Two of the patients had AIDS and the other had been treated for lymphoma. All cases were diagnosed by histopathologic examination in stereotactic brain biopsies.
Acquired Immunodeficiency Syndrome
;
Astrocytes
;
Biopsy
;
Brain
;
Brain Neoplasms
;
Demyelinating Diseases
;
Humans
;
Immunocompromised Host*
;
JC Virus
;
Leukoencephalopathy, Progressive Multifocal*
;
Lymphoma
;
Macrophages
;
Oligodendroglia
;
Rare Diseases
5.Difference of Hypoxia Tolerance with Reference to Sex.
Jae Moon CHOI ; Chan Kwon JUNG ; Tae Hyung MIN ; Won Keun LEE
Korean Journal of Aerospace and Environmental Medicine 2003;13(3):131-135
BACKGROUND: Time of useful consciousness is related with various factors including smoking, age, sex, drug, and temperature. It is still unclear whether acute hypoxia tolerance is different between male and female. METHOD: We included 32 healthy students (male, n=16; female, n=16) volunteered to participate in this study. The blood hemoglobin concentration was measured at a day before flight. With high altitude rapid decompression flight training chamber, flight to simulated altitude of 25,000 ft was performed after nitrogen extraction breath. At 25,000 ft, heart rate and arterial O2 saturation (SaO2) were measured by using pulse oximeter after taking off oxygen mask. We compared the duration from mask-off to the time at 60% SaO2 between male and female and correlated the time at 60% SaO2 with hemoglobin concentration. RESULTS: The duration from mask-off to SaO2 reaching 60% were significantly longer in the male group. There was a linear relationship between hemoglobin concentration and time at 60% SaO2. CONCLUSION: Acute hypoxia tolerance differs from the two sexes and the difference of hemoglobin concentration is one of possible causative factors of this difference.
Altitude
;
Anoxia*
;
Consciousness
;
Decompression
;
Female
;
Heart Rate
;
Humans
;
Male
;
Masks
;
Nitrogen
;
Oxygen
;
Smoke
;
Smoking
6.The Clinical Effect of Botulinum Toxin in a Patient with Tourette's Syndrome : A Case Report and Review.
Jung Keun HYUN ; Jun Hyung LEE ; Chang Min LEE ; Myung Ho LIM
Journal of the Korean Academy of Child and Adolescent Psychiatry 2013;24(2):90-95
Botulinum toxin, a neurotoxin, is known to be an inhibitor of cholinergic neuromuscular transmission. Recently, it was reported that the administration of botulinum toxin is effective for the treatment of focal neurological motor disorders such as cervical dystonia, blepharospasm, hemifacial spasm, spasmodic dysphonia, and writer's cramp. Several case studies reported that the botulinum toxin was administered for the treatment of motor tic or vocal tic. It was found that this toxin reduces the frequency and severity of the tic as well as the premonitory urge and symptoms. In our case study, a noticeable decrease of motor tic symptom was observed after an intramuscular injection of 300mg of botulinum toxin in an 18-year-old patient with Tourette's disorder who showed only a little improvement of motor tic and vocal tic symptoms after treatment with antipsychotic drugs for several years. This case is reported in our study and literature survey was undertaken for reviewing similar cases. In our study, an 18-year-old boy diagnosed with Tourette's disorder based on Diagnostic and Statistical Manual of Mental Disorders, fourth edition presented with the following scores : the Clinical Global Impression scale, Yale Global Tic Severity Scale (motor/vocal/severity), Premonitory Urge Score, Korean Attention-Deficit Hyperactivity Disorder Rating scale, and Kovac Depression scale which were performed prior to the treatment were 5, 21/5/50, 100, 17, and 18 points, respectively. Two weeks after the injection of botulinum toxin, the scores were 4, 17/5/40, 50, 16, and 19 points, respectively. Eight weeks after the injection of botulinum toxin, they had become 3, 15/5/30, 25, 16, and 20 points, respectively, which clearly indicates a noticeable decrease of motor tic symptom.
Antipsychotic Agents
;
Blepharospasm
;
Botulinum Toxins
;
Depression
;
Diagnostic and Statistical Manual of Mental Disorders
;
Dysphonia
;
Dystonic Disorders
;
Hemifacial Spasm
;
Humans
;
Injections, Intramuscular
;
Tics
;
Torticollis
;
Tourette Syndrome
7.A case of citrobacter freundii osteomyelitis.
Hyung Goo CHO ; Dong Sig KIM ; Hwang Min KIM ; Jae Seung YANG ; Baek Keun LIM ; Jong Soo KIM
Journal of the Korean Pediatric Society 1991;34(3):408-412
No abstract available.
Citrobacter freundii*
;
Citrobacter*
;
Osteomyelitis*
8.A case of citrobacter freundii osteomyelitis.
Hyung Goo CHO ; Dong Sig KIM ; Hwang Min KIM ; Jae Seung YANG ; Baek Keun LIM ; Jong Soo KIM
Journal of the Korean Pediatric Society 1991;34(3):408-412
No abstract available.
Citrobacter freundii*
;
Citrobacter*
;
Osteomyelitis*
9.Anatomic Study on the Cortical Branches of the Middle Cerebral Artery in Koreans.
Sa Min HONG ; Hyung Keun SONG ; Nam Kyu YOO ; In Hyuk CHUNG
Korean Journal of Physical Anthropology 2002;15(4):241-249
The purpose of this study was to identify the branching patterns and the distribution of the cortical branches of the middle cerebral artery (MCA) in 100 cerebral hemispheres of Korean adults. The intracranial arteries were perfused with red latex compounds. The territory of the MCA was divided into 12 areas: orbitofrontal, prefrontal, precentral, central, anterior parietal, posterior parietal, angular, temporo -occipital, posterior temporal, middle temporal, anterior temporal and temporopolar. Branching pattern of the main trunk of the MCA was divided into five types: Type I: a single -trunk type of MCA in 34% of cases; Type II: bifurcation (57%); Type III: trifurcation (5%); Type IV: quadrifurcation (1%); Type V: two MCAs originated from the internal carotid artery (3%). The MCA of the bifurcation type was classified into equal bifurcation (20%), superior trunk dominant (11%) and inferior trunk dominant (26%) according to the cortical area. The superior trunk of the equal bifurcation supplied from the orbitofrontal to posterior parietal area. The outer diameter of the main trunk of the MCA was 3.15 +/-0.52 mm on average. The anatomical types of the MCA were discussed with the related symptoms in disease of the MCA.
Adult
;
Arteries
;
Carotid Artery, Internal
;
Cerebrum
;
Humans
;
Latex
;
Middle Cerebral Artery*
;
Rabeprazole
10.Treatment of Fractures of the Femur Neck in Children
In KIM ; Jin Young KIM ; Hyung Min KIM ; Jon Hoon PARK ; Ki Won KIM ; Sung Keun LEE ; Seoung Koo RHEE
The Journal of the Korean Orthopaedic Association 1996;31(3):426-433
We have treated total 37 cases of femoral neck fracture in children who were under the 16 years old in age at the Catholic University Medical College since 1985, followed them for average 21 months to analyse their types of fracture and treatment, complications and prevention of complications, and obtained the following results. 1. According to the Delbet's classification, type I was 1 case, II were 18(49%), most common, III were 10 and IV were 8 cases. Their ages were average 8.2 years and boys were predominant in 27 cases. 2. Thirty-six cases were treated with open reduction and internal fixation within 1-13 days after fracture, but only one type IV was treated with closed reduction, followed by hip spica cast for 6 to 9 weeks in all. 3. The fixation devises were removed at average 8.7 months after operatio. 4. fifteen complications were observed in 11 cases(37%), that were AVN(3 cases), early physeal closure(8 cases), coxa vara(3 cases), coxa valga and limb shortening(each 1 case), and their causes were severe fracture displacement(2 cases), penetration of fixation devices to physis(8 cases), incomplete reduction and loss of initial reductio (1 case) etc, but were not correlated with their method of fracture treatment. Conclusively, the femur neck fracture in children could favorably be treated with open reduction and internal fixation to reduce their complications. Physeal early closures due to penetration of screws and pin were most common cause of complications, and their long-term follow-up should be necessary.
Child
;
Classification
;
Coxa Valga
;
Extremities
;
Femoral Neck Fractures
;
Femur Neck
;
Femur
;
Follow-Up Studies
;
Hip
;
Humans
;
Methods