1.Clinicopathological Study of 191 Cases of Metastatic Skin Cancers from Solid Cancer Diagnosed at the Department of Dermatology in a Tertiary Referral Cancer Center
Hyung Keon PARK ; Sook Jung YUN
Korean Journal of Dermatology 2023;61(1):13-21
Background:
Metastatic skin cancers occur when cancer cells metastasize to the skin as the primary cancer progresses, but few studies in Korea have included a large number of patients.
Objective:
To analyze the clinicopathological characteristics of metastatic skin cancers originating from solid cancers.
Methods:
A total of 191 patients with metastatic skin cancer diagnosed by skin biopsy from April 2004 to December 2021 were retrospectively analyzed. Data on age, sex, duration, symptoms, clinical manifestations, metastatic sites, and histopathological findings were obtained from medical records and photographs.
Results:
The mean age of onset was 65.3 years, the male/female ratio was 80:111, and the mean duration was 3.3 months. Most patients were asymptomatic (65.4%), and the most frequent manifestation was nodular lesions (64.4%). Among the 191 metastatic skin cancers, the most common primary cancers were breast cancer (31.9%), lung cancer (25.7%), and melanoma (18.8%). The most common primary cancer in males was lung cancer (52.5%), and that in females was breast cancer (54.1%). The most common sites of metastatic skin cancer were the chest (26.6%), scalp (17.9%), abdomen (10.6%), and back (9.2%). The most common histopathological finding of metastatic skin cancer was adenocarcinoma (53.4%), followed by melanoma (18.8%) and squamous cell carcinoma (14.7%).
Conclusion
We believe that this study will be helpful in diagnosing metastatic skin cancer in patients with a history of cancer or a newly diagnosed primary cancer.
2.The graft survival rates and stability of renal allograft function associate with cyclosporine immunosuppressive therapy.
Keon Hyung SUNG ; Kgoungwon KAHNG ; Sung Hoon CHUNG ; Chan Hyun PARK ; Chong Myung KANG ; Hac Chul PARK ; Jin Young KWACK
The Journal of the Korean Society for Transplantation 1991;5(1):1-15
No abstract available.
Allografts*
;
Cyclosporine*
;
Graft Survival*
;
Transplants*
3.The graft survival rates and stability of renal allograft function associate with cyclosporine immunosuppressive therapy.
Keon Hyung SUNG ; Kgoungwon KAHNG ; Sung Hoon CHUNG ; Chan Hyun PARK ; Chong Myung KANG ; Hac Chul PARK ; Jin Young KWACK
The Journal of the Korean Society for Transplantation 1991;5(1):1-15
No abstract available.
Allografts*
;
Cyclosporine*
;
Graft Survival*
;
Transplants*
4.Pseudosarcoma of the esophagus: one case report.
Chang Hoi KIM ; Keon LEE ; Hyung Joo PARK ; Young Ho CHOI ; Hark Jei KIM ; Hyoung Mook KIM
The Korean Journal of Thoracic and Cardiovascular Surgery 1991;24(12):1197-1200
No abstract available.
Esophagus*
5.Clinical analysis on relation between blood flow and patency of arteriovenous fistula for hemodialysis.
Chang Hoi KIM ; Keon LEE ; Hyung Joo PARK ; Young Ho CHOI ; Hark Jei KIM ; Hyoung Mook KIM
The Korean Journal of Thoracic and Cardiovascular Surgery 1991;24(12):1167-1172
No abstract available.
Arteriovenous Fistula*
;
Renal Dialysis*
6.Effects of gout and hyperuricemia on renal function.
Keon Hyung SUNG ; Sung Hoon CHUNG ; Kyeng Won KANG ; Jung Ho KIM ; Ji Hoon KIM ; Chan Hyun PARK ; Chong Myung KANG ; Han Chul PARK
Korean Journal of Nephrology 1991;10(4):518-525
No abstract available.
Gout*
;
Hyperuricemia*
7.Healthy cities approach as a new paradigm of public health policy.
Jinhee KIM ; Won Gi JHANG ; Eunjeong KANG ; Kwangwook KOH ; Keon Yeop KIM ; Kwan Jun PARK ; Yoon Hyung PARK
Journal of the Korean Medical Association 2011;54(8):884-891
The healthy cities approach emphasizes the role of the leadership of local governments in promoting the health of the population in city settings. The concept emerged from public health strategies declared in the Ottawa Charter for Health Promotion, and reflects the characteristics of the third public health revolution. The Korean healthy cities movement, characterized by voluntary participation of local governments in the Alliance for Healthy Cities, has grown rapidly in recent years. A strong push of the healthy cities movement by a local government without a profound commitment to the vision may hinder the effective and sustainable development of the movement. By reviewing the historical background and significance of the healthy cities movement and its underlying concepts, and illustrating the main strategies and goals of the movement, that is, the development of partnerships, community participation and empowerment, and working in networks for stimulating change, this article argues that the healthy cities movement is a potent vehicle for implementing the new paradigm of public health introduced to local governments. We also argue that the Korean healthy cities movement needs more active participants and more support of the central government and other related stakeholders.
Consumer Participation
;
Health Promotion
;
Korea
;
Local Government
;
Natural Resources
;
Power (Psychology)
;
Public Health
;
Vision, Ocular
8.Study on the Factors Affecting the Chronic Renal Allograft Dysfunction.
Keon Hyung SUNG ; Kyoung Won KAHNG ; Chong Myung KANG ; Jin Young KWAK ; Tae Sung PARK ; Seung Yeon LEE
Korean Journal of Nephrology 1998;17(3):483-493
We studied the chronic renal allograft dysfunction in Korean renal transplants from 1 year after transplantation to 5 years. We evaluated renal function by simply using the reciprocal serum creatinine level and sought to find factors affecting the value of the reciprocal serum creatinine and graft survival, and changes of the slope of reciprocal serum creatinine. We also estimated the reciprocal serum creatinine from demographic parameters and routine laboratory results. This study included 114 patients, 87 male and 27 female who underwent renal transplantations and had functioning allografts for more than 18 month after transplantation. The results were as follows. 1) The reciprocal serum creatinine level decreased slowly and linearly. 2) There were many factors related to the reciprocal creatinine, including blood urea nitrogen, serum uric acid level, age of donors, sex of recipients, presence of acute rejecton, age of recipient, serum phosphorus, white cell count in blood, cyclosporine level in blood, hemoglobin level, posttransplantation period. We could derive the estimated reciprocal serum creatinine from data of the patients. 3) The age of the recipient and cyclosporine level at 1 year after transplantation affected the slope of the reciprocal serum creatinine during follow-up time. 4) There were 16 graft loss, including 3 functioning graft loss and 13 graft loss due to chronic allograft dysfunction. 5) Besides creatinine and BUN level at 1 year, higher blood pressure and proteinuria and lower hemoglobin levels at 1 year after transplantation were related to the graft loss from chronic allograft dysfunction. 6) There were more chronic allograft loss in patients who had lower actuarial reciprocal serum creatinine than estimated reciprocal serum creatinine. Because follow-up time was relatively short and there were only mild increases in serum creatinine level in our study, follow up of our patients for a longer-term period is required to find other factors affecting the renal allograft dysfunction.
Allografts*
;
Blood Pressure
;
Blood Urea Nitrogen
;
Cell Count
;
Creatinine
;
Cyclosporine
;
Female
;
Follow-Up Studies
;
Graft Survival
;
Humans
;
Kidney Transplantation
;
Male
;
Phosphorus
;
Proteinuria
;
Tissue Donors
;
Transplants
;
Uric Acid
9.Comparison of surgical condition in endoscopic sinus surgery using remifentanil combined with propofol, sevoflurane, or desflurane.
Hyung Seok YOO ; Jin Hee HAN ; Sung Wook PARK ; Keon Sik KIM
Korean Journal of Anesthesiology 2010;59(6):377-382
BACKGROUND: Various maneuvers are commonly used to achieve the ideal operative field necessary for successful endoscopic sinus surgery (ESS). There are a few contradictory reports on this subject and the consensus is that propofol anesthesia results in a better or similar surgical field and less or similar amount of bleeding than volatile anesthesia. The aim of this study was to compare the surgical field in patients in whom intravenous anesthesia is used as opposed to balanced general anesthesia. METHODS: Sixty patients undergoing ESS were randomly assigned into three groups, each of which used a different type of anesthesia: propofol/remifentanil (PRO/REM) group, sevoflurane/remifentanil (SEV/REM) group, and desflurane/remifentanil (DES/REM) group. We aimed to maintain the intraoperative mean blood pressure (MBP) at 65 mmHg and the heartrate (HR) at about 75 beats per minute. The quality of visibility of the surgical field was graded, using a validated scoring system, 60 minutes after the start of the operation. RESULTS: All groups had a similar MBP and mean HR at 60 minutes after the operation started. There was no significant differences among the three groups for surgical grade score (P = 0.83). CONCLUSIONS: In this comparative study of three anesthetic combinations (PRO/REM, SEV/REM, and DES/REM) in patients undergoing ESS with controlled BP and HR, we did not observe any significant differences in the surgical grade scores.
Anesthesia
;
Anesthesia, Intravenous
;
Blood Pressure
;
Consensus
;
Hemorrhage
;
Humans
;
Isoflurane
;
Methyl Ethers
;
Piperidines
;
Propofol
;
Sinusitis
10.The Distant Management System of BPH Patients using the Tele-communications.
Moon Seon PARK ; Yun Seok HA ; Keon Myung LEE ; Wun Jae KIM ; Hyung Lae LEE
Korean Journal of Urology 2006;47(5):489-492
PURPOSE: As our society ages, a disease like benign prostatic hyperplasia (BPH) are increasing and needs consequent management. Recently, through the expansion of the communication infrastructure and terminals, a network services can be provided. However, the concern about distant medical management is increasing. We introduce here the Personal BPH Control Program (PBCP) and its application to clinical patients. MATERIALS AND METHODS: We have asked BPH patients to input the variable elements on the digital survey through the Personal Digital Assistant (PDA) once a week. We used the International Prostate Symptom Score (IPSS) and the average flow rate as the variable elements. We have used an algorithm to determine the patients condition. With this, we have developed a program that helps patients to adjust their visits to the hospital. RESULTS: According to the input elements, we have determined that the patients' condition was good (visit the hospital every 3 months) when the IPSS decreased, compared with the baseline and when the average flow rate was up above 2ml/sec. The patients' condition was a warning (visit the hospital every 2 months) when the IPSS was increased to below 3 and the average flow rate was down below +/- 2ml/sec, and the patients' condition was urgent when the IPSS increased to above 4 and the average flow rate was down above 3ml/sec. CONCLUSIONS: We expect that the PBCP has great socioeconomic utility when applying it to patients. A portable personal apparatus for measuring the flow rate is now being developed. When sufficient examples of applying the symptom algorithm have accumulated, we are going to report afterward the prospects of using the PBCP in the future.
Computers, Handheld
;
Humans
;
Prostate
;
Prostatic Hyperplasia
;
Telecommunications