1.Late Infantile Metachromatic Leukodystrophy-Arylsulfatase A Assay in 24h Urine.
Hong Jin LEE ; Yong Joon SHIN ; Yong Seung HWANG ; Hyung Ro MOON ; Jeong Seon SEO
Journal of the Korean Pediatric Society 1989;32(7):978-983
No abstract available.
2.Feasibility of Novel Three-Dimensional Magnetic Resonance Fingerprinting of the Prostate Gland:Phantom and Clinical Studies
Dongyeob HAN ; Moon Hyung CHOI ; Young Joon LEE ; Dong-Hyun KIM
Korean Journal of Radiology 2021;22(8):1332-1340
Objective:
To evaluate the feasibility of a new three-dimensional (3D) MR fingerprinting (MRF) technique for the prostate gland by conducting phantom and clinical studies.
Materials and Methods:
The new 3D MRF technique used in this study enables quick data acquisition and has a high resolution. For the phantom study, the MRF T1 and T2 values in an in-house phantom were compared with those of goldstandard mapping methods using linear regression analysis. For the clinical study, we evaluated 90 patients who underwent prostate imaging with MRF for suspected prostate cancer between September 2019 and February 2020. The mean T1 and T2 values were compared in the peripheral zone, transition zone, and focal lesions using paired t tests. The differences in the T1 and T2 values according to cancer aggressiveness were evaluated using one-way analysis of variance.
Results:
In the phantom study, the MRF T1 and T2 values showed a perfect correlation with the gold-standard T1 and T2 values (R > 0.99). In the clinical study, the T1 and T2 values in the peripheral zone were significantly higher than those in the transitional zone (p < 0.001, both). The T1 and T2 values in prostate cancer were significantly lower than those in the peripheral and transitional zones. The higher the grade of cancer, the lower the T2 values.
Conclusion
The T1 and T2 values obtained from the 3D MRF showed a perfect correlation with the gold standard values in the phantom study. Differences in the T1 and T2 values among the different zones of the prostate gland were identified using 3D MRF in patients.
3.Feasibility of Novel Three-Dimensional Magnetic Resonance Fingerprinting of the Prostate Gland:Phantom and Clinical Studies
Dongyeob HAN ; Moon Hyung CHOI ; Young Joon LEE ; Dong-Hyun KIM
Korean Journal of Radiology 2021;22(8):1332-1340
Objective:
To evaluate the feasibility of a new three-dimensional (3D) MR fingerprinting (MRF) technique for the prostate gland by conducting phantom and clinical studies.
Materials and Methods:
The new 3D MRF technique used in this study enables quick data acquisition and has a high resolution. For the phantom study, the MRF T1 and T2 values in an in-house phantom were compared with those of goldstandard mapping methods using linear regression analysis. For the clinical study, we evaluated 90 patients who underwent prostate imaging with MRF for suspected prostate cancer between September 2019 and February 2020. The mean T1 and T2 values were compared in the peripheral zone, transition zone, and focal lesions using paired t tests. The differences in the T1 and T2 values according to cancer aggressiveness were evaluated using one-way analysis of variance.
Results:
In the phantom study, the MRF T1 and T2 values showed a perfect correlation with the gold-standard T1 and T2 values (R > 0.99). In the clinical study, the T1 and T2 values in the peripheral zone were significantly higher than those in the transitional zone (p < 0.001, both). The T1 and T2 values in prostate cancer were significantly lower than those in the peripheral and transitional zones. The higher the grade of cancer, the lower the T2 values.
Conclusion
The T1 and T2 values obtained from the 3D MRF showed a perfect correlation with the gold standard values in the phantom study. Differences in the T1 and T2 values among the different zones of the prostate gland were identified using 3D MRF in patients.
4.Septal surgery using crushed cartilage.
Moon Suh PARK ; Hyung Moo LEE ; Kyung Hun YANG ; Ki Beom SONG ; Hyun Joon LIM
Korean Journal of Otolaryngology - Head and Neck Surgery 1991;34(2):271-277
No abstract available.
Cartilage*
5.The Complication in the Treatment Modality of Intertrochanteric Fracture of Femur
Joon Soon KANG ; Seung Rim PARK ; Young Hoon KIM ; Hyung Soo KIM ; Kyoung Ho MOON
The Journal of the Korean Orthopaedic Association 1995;30(1):104-114
Intertrochanteric fractures of femur were increasing in their incidence in morden life. The compression hip screw and Ender nail are popular treatment modalities of the interochanteric fracture of femur. We had tried to clarify the complications of intertrochanteric fracture according to the treatment modality-compression hip screw and Ender nail. We obtained the results as followings with the patients who had intertrochanteric fracture of femur which were managed by compression hip screw (56 cases) and Ender nail (22 cases) through the period of March 1987 to June 1993. The summary of the results; 1. Mechanical complications were developed in 9 patients(16%), 9 complications in the group with compression hip screw and 7 patients(32%), 12 complications in Ender nail. 2. Local complications were developed in 4 patients(7%) in compression hip screw and 10 patients (46%) in Ender nail and the most common local complication was the knee joint pain(7 patients; 32%). 3. Statistically, more significant decrease of neck-shaft angle was shown with group using Ender nail for unstable fracture than stable fracture group and compression hip screw group. 4. The degree of shortening was incrased in group with Ender nail than in group with compression hip screw, but there was no statistical significance. 5. The grade of osteoporosis was not related to the change of neck-shaft angle and shortening and also to the development of mechanical complication. According to the above results, compression hip screw was a more stable fixation device than Ender nail in the unstable intertrochanteric fracutre.
Femur
;
Hip
;
Hip Fractures
;
Humans
;
Incidence
;
Knee Joint
;
Osteoporosis
6.Anterior Decompression and Fixation with Kaneda Instrument of Trhoracolumbar and Lumbar Spine Fracture
Joon Soon KANG ; Seung Rim PARK ; Hyung Soo KIM ; Kyoung Ho MOON ; Seung Kyu LEE
The Journal of the Korean Orthopaedic Association 1995;30(2):355-363
There have long been a lot of controversies on the treatment of unstable thoracolumbar spine fracture, and the role of decompression is also controversial. Compression of the neural elements by retropulsed bone fragments can be relieved indirectly by the reduction with posterior instrumentation or directly by the exploration of the spinal canal through a posterolateral or anterior approach. There is no universal agreement about the indications for each of these method. Authors analyzed the result of 24 cases of thoracolumbar spine fracture which had been operated by anterior decompression and Kaneda instrumentation from the February 1990 to May 1993 at Inha general hospital. The results were as follows: 1. The most common cause of injury was falling from a height, 20 cases (83.3%). And the 12 cases were in the 4th decade, with an average age of 37.7 years. 2. According to McAfee classification, there were 7 stable(29.2%) and 15 unstable bursting fractures(62.5%). And the most common level of injury was L1(11 cases, 45.8%). 3. Neurologic status was improved one or more grade(Frankel grade) in 21 cases except one case of complete paraplegia. 4. The average correctional angle of kyphotic deformity was 13.1° immediate postoperatively, and the loss of correction(average, 6.7°) was observed during the follow-up period. 5. The segmental instability was found at the level below the fusion in three cases during the follow-up period. 6. There was neither failure of instrument, dislodgement of graft bone nor lateral wedging during the follow-up period.
Accidental Falls
;
Classification
;
Congenital Abnormalities
;
Decompression
;
Follow-Up Studies
;
Hospitals, General
;
Methods
;
Paraplegia
;
Spinal Canal
;
Spine
;
Transplants
7.The Analysis of FHR Parameters and Canonical Correlation of Fetuses with Breech Presentation.
Moon Il PARK ; Jung Hye HWANG ; Hyung MOON ; Sang Soon YOON ; Kyung Joon CHA ; Young Sun PARK ; Je Seon RYU
Korean Journal of Perinatology 2001;12(3):301-308
No abstract available.
Breech Presentation*
;
Female
;
Fetus*
;
Pregnancy
8.Measurement of Angle Kappa Using Ultrasound Biomicroscopy and Corneal Topography.
Joon Hyung YEO ; Nam Ju MOON ; Jeong Kyu LEE
Korean Journal of Ophthalmology 2017;31(3):257-262
PURPOSE: To introduce a new convenient and accurate method to measure the angle kappa using ultrasound biomicroscopy (UBM) and corneal topography. METHODS: Data from 42 eyes (13 males and 29 females) were analyzed in this study. The angle kappa was measured using Orbscan II and calculated with UBM and corneal topography. The angle kappa of the dominant eye was compared with measurements by Orbscan II. RESULTS: The mean patient age was 36.4 ± 13.8 years. The average angle kappa measured by Orbscan II was 3.98°± 1.12°, while the average angle kappa calculated with UBM and corneal topography was 3.19°± 1.15°. The difference in angle kappa measured by the two methods was statistically significant (p < 0.001). The two methods showed good reliability (intraclass correlation coefficient, 0.671; p < 0.001). Bland-Altman plots were used to demonstrate the agreement between the two methods. CONCLUSIONS: We designed a new method using UBM and corneal topography to calculate the angle kappa. This method is convenient to use and allows for measurement of the angle kappa without an expensive device.
Corneal Topography*
;
Humans
;
Male
;
Methods
;
Microscopy, Acoustic*
;
Ultrasonography*
9.A Case of a Bitemporal Atrophic Scar induced by Morphea, and treated by Autologous Fat Transplantation.
Hyung Su KIM ; Young Joon CHO ; Sang Eun MOON
Korean Journal of Dermatology 2005;43(9):1257-1259
A contour change induced by a subcutaneous depleting disorder such as lupus or morphea can be corrected by filling the defect with an artificial or natural materials of the types of fillers, autologous fat is popularly utilized for volumetric correction. Autologus fat has many advantages, such as easy harvesting, free volume, and non-immunogenicity. Herein, we report a case who of a bilateral atrophic scar on the temple area induced by morphea which was successfully treated by autologous fat transplantation.
Cicatrix*
;
Scleroderma, Localized*
10.MR findings of craniopharyngiomas.
Hyung Seok KIM ; In One KIM ; Moon Hee HAN ; Sang Joon KIM ; Chang Hae SUH ; Kee Hyun CHANG
Journal of the Korean Radiological Society 1993;29(1):14-19
A retrospective analysis on the MRI findings of 24 pathologically contirmed craniopharyngiomas was performed with emphasis on signal intensity of cystic portion and its chemical components. Axial, coronal MR scans were ontained, and in six patients, post-contrast study was done with Gadopentetate Dimeglumine(Gd-DTPA). In 14 cystic portions were aspirated to correlate the amount of chemical components such as calcium, glucose, protein, cholesterol, lipid, and iron with the signal intensity GT scans were also performed in 20 patients. In eight cases, tumors extended to subfrontal, third ventricle, and retrosellar area the extensions were well demonstrated in sagittal and coronal images. The signal intensity of cystic lesions on T2WI were variable but tended to be higher in high protein and iron contents. Calcifications were present in 20 cases and out of these, MRI detected calcification as very low signal intensity or signal void on T1WI and T2WI in 12 cases. Multiplanar imaging of MRI was very useful for the evaluation of tumor extension and the signal intensity of the cystic lesion tended to be higher on T1WI when the contents had high protein or iron components.
Calcium
;
Cholesterol
;
Craniopharyngioma*
;
Glucose
;
Humans
;
Iron
;
Magnetic Resonance Imaging
;
Retrospective Studies
;
Third Ventricle