1.Variation of the External Ocular Muscular Artery.
Hye Yeon LEE ; In Hyuk CHUNG ; Won Seok SIR ; Ki Suk KOH ; Hyung Joon KOH ; Young Jae HONG
Journal of the Korean Ophthalmological Society 1992;33(12):1218-1227
The muscular branches of the ophthalmic artery have been described as the superior muscular artery and the inferior muscular artery. However, the definition of the muscluar arteries and their distribution has not been clarified. Therefore, the muscular branches of the ophthalmic artery in 80 orbits of Korean adults were observed under the surgical microscope. The inferior muscular artery was observed in 87.5% of the materials and the superior muscular artery was observed in 32.5%. The commen muscular branch distributing to the adjacent two muscles was observed more frequently(81.3%). The superior muscular artery and the common muscular branches were similar in their distribution according to their site of origin. Therefore, they were classified into the superolateral and superomedial arteries. The superolateral muscular artery was observed in 58.6%. and the superomedial muscular artery was observed in 71.3%. This study suggests that the ocular muscular arteries are better classified into 3 groups, namely inferior, superolateral, and superomedial muscular arteries.
Adult
;
Arteries*
;
Humans
;
Muscles
;
Ophthalmic Artery
;
Orbit
2.Variation of the External Ocular Muscular Artery.
Hye Yeon LEE ; In Hyuk CHUNG ; Won Seok SIR ; Ki Suk KOH ; Hyung Joon KOH ; Young Jae HONG
Journal of the Korean Ophthalmological Society 1992;33(12):1218-1227
The muscular branches of the ophthalmic artery have been described as the superior muscular artery and the inferior muscular artery. However, the definition of the muscluar arteries and their distribution has not been clarified. Therefore, the muscular branches of the ophthalmic artery in 80 orbits of Korean adults were observed under the surgical microscope. The inferior muscular artery was observed in 87.5% of the materials and the superior muscular artery was observed in 32.5%. The commen muscular branch distributing to the adjacent two muscles was observed more frequently(81.3%). The superior muscular artery and the common muscular branches were similar in their distribution according to their site of origin. Therefore, they were classified into the superolateral and superomedial arteries. The superolateral muscular artery was observed in 58.6%. and the superomedial muscular artery was observed in 71.3%. This study suggests that the ocular muscular arteries are better classified into 3 groups, namely inferior, superolateral, and superomedial muscular arteries.
Adult
;
Arteries*
;
Humans
;
Muscles
;
Ophthalmic Artery
;
Orbit
3.Clinical Outcomes of CyberKnife Radiotherapy in Prostate Cancer Patients: Short-term, Single-Center Experience.
Dong Hoon KOH ; Jin Bum KIM ; Hong Wook KIM ; Young Seop CHANG ; Hyung Joon KIM
Korean Journal of Urology 2014;55(3):172-177
PURPOSE: In this retrospective study, we analyzed the outcomes of prostate cancer patients treated with the CyberKnife radiotherapy system (Accuray). MATERIALS AND METHODS: Between 2007 and 2010, 31 patients were treated for prostate cancer by use of the CyberKnife radiotherapy system. After excluding six patients who were lost to follow-up, data for the remaining 25 patients were analyzed. Patients were divided into the CyberKnife monotherapy group and a postexternal beam radiotherapy boost group. Clinicopathologic features and treatment outcomes were compared between the groups. The primary endpoint was biochemical recurrence-free survival period based on the Phoenix definition. Toxicities were evaluated by using the Radiation Therapy Oncology Group scoring criteria. RESULTS: Of 25 patients, 17 (68%) and 8 (32%) were classified in the monotherapy and boost groups, respectively. With a median follow-up of 29.3 months, most of the toxicities were grade 1 or 2 except for one patient in the boost group who experienced late grade 3 gastrointestinal toxicity. The overall biochemical recurrence rate was 20% (5/25) and the median time to biochemical recurrence was 51.9 months. None of the patients with low or intermediate risk had experienced biochemical recurrence during follow-up. Among D'Amico high-risk populations, 16.7% (1/6) in the monotherapy group and 50.0% (4/8) in the boost group experienced biochemical recurrence. CONCLUSIONS: Our data support that prostate cancer treatment by use of the CyberKnife radiotherapy system is feasible. The procedure can be a viable option for managing prostate cancer either in a monotherapy setting or as a boost after conventional radiotherapy regardless of the patient's risk stratification.
Follow-Up Studies
;
Humans
;
Lost to Follow-Up
;
Prostate*
;
Prostatic Neoplasms*
;
Radiosurgery
;
Radiotherapy*
;
Recurrence
;
Retrospective Studies
4.Comparative Analysis of Graft Patency and Limb Salvage Rate in DM & Non-DM after Infrainguinal Arterial Reconstruction.
Hyung Joon AHN ; Ho Chul PARK ; Suck Hwan KOH ; Soo Myung OH ; Choong YOON
Journal of the Korean Society for Vascular Surgery 2000;16(1):71-77
PURPOSE: The purpose of this study is to compare and analyze the results of primary and secondary patency rates and limb salvage rates in DM (Diabetes Mellitus) and Non-DM patients with atherosclerosis in the lower extremity after arterial reconstruction. METHODS: A retrospective study was done by reviewing admission notes and follow up records of 95 atherosclerotic limbs which had infrainguinal arterial reconstruction due to claudication induced severe impediment and limb threatening ischemia (reat pain, minor and major tissue loss). Kaplan-Meier survival analysis was used in the comparison of the primary, secondary patency rates and limb salvage rates, and statistical examination was handled by the Log-Rank significance test. RESULTS: 1 and 3 year primary patency rates were 76.0% and 65.6% each in the DM group and 63.9% and 56.5% each in the Non-DM group. 1 and 3 year secondary patency rates were 80.0% and 69.7% in DM patients and 81.1%, 73.9% each in Non-DM patients. The 1 and 3 year limb salvage rates of DM patients were 83.8% and 72.6% while Non-DM patients revealed a 84.9% and 77.8%. CONCLUSION: Aggressive arterial reconstruction is recommended as well, in DM patients with atherosclerosis in the lower extremity, considering the insignificant differences in the risk of surgery as well as the primary, secondary patency rates and limb salvage rates.
Atherosclerosis
;
Extremities*
;
Follow-Up Studies
;
Humans
;
Ischemia
;
Limb Salvage*
;
Lower Extremity
;
Retrospective Studies
;
Transplants*
5.A case of functioning adrenal rest tumor of liver.
Tae Geun OH ; Jae Joon KOH ; Kyong Soo PARK ; Seong Yeon KIM ; Hong Kyu LEE ; Hun Ki MIN ; Young Il KIM ; Soo Tae KIM ; Jae Hyung PARK
Korean Journal of Medicine 1993;45(4):516-521
No abstract available.
Adrenal Rest Tumor*
;
Liver*
6.Treatment of Non-union Distal Humerus Fractures after Operation.
Hyung Sik KIM ; Ki Joon JANG ; Yun Rak CHOI ; Il Hyun KOH ; Ho Jung KANG
Journal of the Korean Fracture Society 2012;25(4):310-316
PURPOSE: This study is a retrospective analysis of patients who had undergone surgical treatment for non-union of distal humerus fracture. We evaluated them in terms of causes of injury, radiologic findings, and clinical outcomes such as prognosis. MATERIALS AND METHODS: Seven consecutive radiologic patients who were confirmed to have nonunion of a distal humerus fracture underwent reoperations. These patients had already undergone operations for distal humerus fractures. This survey was held from 2005 to 2010. The average period up to diagnosis of non-union after the first operation was 7.4 months (4 to 16 months). The mean follow-up period was 24.6 months (12 to 65 months). Each patient was graded functionally according to the Mayo Elbow Performance Score and the Disabilities of the Arm, Shoulder and Hand Score. RESULTS: Osteosynthesis was performed by internal fixation with plates and screws and then a bone graft for non-union of the distal humerus fracture. The average range of motion within the elbow joints was found to be a flexion contracture of 18.8 degrees (0~30 degrees) and further flexion of 120.2 degrees (102~140 degrees). Among postoperative complications, three cases of medium-degree stiffness, two cases of medial column nonunion, and one case of dissociation of the internal fixator were reported. CONCLUSION: Stable internal fixation for maintenance reduction status is essential after accurate initial anatomical reduction. We concluded that nonunion could be prevented by additional surgical treatment such as autogenous bone graft, if it is necessary.
Arm
;
Contracture
;
Dissociative Disorders
;
Elbow
;
Elbow Joint
;
Follow-Up Studies
;
Hand
;
Humans
;
Humerus
;
Internal Fixators
;
Postoperative Complications
;
Range of Motion, Articular
;
Retrospective Studies
;
Shoulder
;
Transplants
7.Cold lesions in Tc-MDP bone scans of patients with skeleted metastases.
Chang Woon CHOI ; Hyung In YANG ; Sang Kyoon BAE ; Dong Soo LEE ; In SON ; Joon Ki JEONG ; Myung Chul LEE ; Chang Soon KOH
Korean Journal of Nuclear Medicine 1993;27(1):98-103
No abstract available.
Humans
;
Neoplasm Metastasis*
8.Animal models of inflammatory bowel disease: novel experiments for revealing pathogenesis of colitis, fibrosis, and colitis-associated colon cancer
Chan Hyung LEE ; Seong-Joon KOH ; Zaher A RADI ; Aida HABTEZION
Intestinal Research 2023;21(3):295-305
Inflammatory bowel disease (IBD), comprising Crohn’s disease and ulcerative colitis, is a lifelong disease that manifests with chronic intestinal inflammation, sequential fibrosis, and an increased risk of colitis-associated colon cancer (CAC). The combined effects of genetic, immunological, environmental, and microbial factors render it difficult to determine the specific mechanism underlying the induction and perpetuation of IBD. Various animal models of IBD have contributed enormously to the understanding of IBD pathogenesis in terms of genomics, transcriptomics, proteomics, microbiome, and drug development of novel therapeutics. Although comprehensive research on IBD has been enabled by advanced technologies, such as genetically engineered models, there is a great need to develop relevant in vivo models of colitis and fibrosis. Here, we review 4 categories of animal models of acute and chronic intestinal inflammation, fibrosis, and CAC: chemically induced, genetically engineered, T cell transfer, and spontaneous gene mutation models.
9.Impact of the Timing of Percutaneous Nephrostomy on the Prognosis of Obstructive Urolithiasis With Sepsis: A Retrospective Cohort Study
Ji Eun YU ; Hyung Joon KIM ; Hong Wook KIM ; Young Seop CHANG ; Jin Bum KIM ; Dong Hoon KOH
Urogenital Tract Infection 2024;19(3):89-96
Purpose:
The aim of this study was to investigate the prognostic impact of time to percutaneous nephrostomy (PCN) insertion on obstructive ureteral stones with sepsis.
Materials and Methods:
Data were collected on patients who presented at our Emergency Department between 2017 and 2021 with obstructive uropathy due to urinary stones and underwent PCN insertion. Patients were stratified into 4 groups in accordance with the quick sepsis-related organ failure (qSOFA) score at presentation (<2 or ≥2) and time to PCN insertion (<4 hours or ≥4 hours) as follows: group 1, qSOFA < 2 and time to PCN insertion < 4 hours; group 2, qSOFA < 2 and time to PCN insertion ≥ 4 hours; group 3, qSOFA ≥ 2 and time to PCN insertion < 4 hours; group 4, qSOFA ≥ 2 and time to PCN insertion ≥ 4 hours. The prognostic impacts of the time to PCN insertion were compared between these groups
Results:
The total cohort consisted of 96 patients, of whom 70 were classified as either group 1 or 2 (qSOFA < 2). Overall, 37 patients had a positive urine culture. The median time to PCN insertion was 218 minutes, and the median length of stay was 14 days. The hospitalization period was significantly shorter in group 3 than in group 4 (p=0.041).
Conclusions
A shorter length of stay was associated with more rapid PCN insertion in patients with obstructive uropathy and a high risk of sepsis.
10.Impact of the Timing of Percutaneous Nephrostomy on the Prognosis of Obstructive Urolithiasis With Sepsis: A Retrospective Cohort Study
Ji Eun YU ; Hyung Joon KIM ; Hong Wook KIM ; Young Seop CHANG ; Jin Bum KIM ; Dong Hoon KOH
Urogenital Tract Infection 2024;19(3):89-96
Purpose:
The aim of this study was to investigate the prognostic impact of time to percutaneous nephrostomy (PCN) insertion on obstructive ureteral stones with sepsis.
Materials and Methods:
Data were collected on patients who presented at our Emergency Department between 2017 and 2021 with obstructive uropathy due to urinary stones and underwent PCN insertion. Patients were stratified into 4 groups in accordance with the quick sepsis-related organ failure (qSOFA) score at presentation (<2 or ≥2) and time to PCN insertion (<4 hours or ≥4 hours) as follows: group 1, qSOFA < 2 and time to PCN insertion < 4 hours; group 2, qSOFA < 2 and time to PCN insertion ≥ 4 hours; group 3, qSOFA ≥ 2 and time to PCN insertion < 4 hours; group 4, qSOFA ≥ 2 and time to PCN insertion ≥ 4 hours. The prognostic impacts of the time to PCN insertion were compared between these groups
Results:
The total cohort consisted of 96 patients, of whom 70 were classified as either group 1 or 2 (qSOFA < 2). Overall, 37 patients had a positive urine culture. The median time to PCN insertion was 218 minutes, and the median length of stay was 14 days. The hospitalization period was significantly shorter in group 3 than in group 4 (p=0.041).
Conclusions
A shorter length of stay was associated with more rapid PCN insertion in patients with obstructive uropathy and a high risk of sepsis.