No abstract available.
Temporomandibular Joint*

The present study proposes a method delineating the extent of the anterior displacement of the temporomandibular articular disc through the angle formed by the deepest point in the glenoid fossa, the center of the mandibular condyle and the junction between the end of the posterior band and the retrodiscal tissue. The method was applied to the normal group and TMD group. The TMD group was further divide into 3 groups Group I(little disc displacement), Group II(anterior disc displacement with reduction) and Group III(anterior disc displacement without reduction). The results were as follows. 1. The normal group showed the location of the articular disc within -10-0degree or with a wider allowance, within -10-10degree from the reference line GC. 2. The TMD group showed the disc located within -21.0-125.8degree,with two peaks at 0-100 and 60-800, suggesting that the group may be composed of more than two different subgroups. 3. The threshold point delineating the normal and TMD states was 0degree, because 82.5% of normal group appeared below 0degree and 94.8% of TMD group appeared above 0degree. 4. Since the angular disc displacement tends to increase from Group I to Group III, the angular displacement increases as the overall severiety of the disease increases, and the chance for a reduction of the disc decreases. 5. The normal group, Group I, Group II, and Group III can be categorized into statistically different groups. The normal group and TMD group can be distinguished in reference to 0degree, while the presence-absence of the anterior disc displacement is judged in reference to 10degree, and the probability of the disc reduction can be estimated in reference to 50degree. The present study assesses the location of the articular disc from the sagittal central section offering a supplementary clinical classification. This system provides an additional information concerning the location of the disc, thereby offering an objective mean to evaluate the progress of the disease. Further studies may be needed on the clinical changes according to location of the disc, as well as the relationship between the morphological changes and the anterior or sideways displacement of the disc.
Classification ; Mandibular Condyle ; Temporomandibular Joint Disc ; Temporomandibular Joint*

Respiratory syncytial virus (RSV) and Influenza virus are the most common pathogen for causing severe upper respiratory infection in all age groups. A multiplex reverse transcription polymerase chain reaction (RT-PCR) has been developed to detect and subtype influenza A (H3N2 and H1N1), B virus and RSV simultaneously in one tube reaction. Amplification with primers derived from conserved sequences within the nucleocapsid for RSV and hemagglutinin subunit for Influenza A (H3N2 and H1N1) and B viruses yielded a 384 bp, a 300 bp, a 236 bp and a 151 bp, respectively. Assay specificity was confirmed by pulse field gel electrophoresis and autosequencing method. Assay sensitivity was 3 PFU/ml of RSV, 22 PFU/ml, 45 PFU/ml of Influenza type A (H3N2 and H1N1) and 6.6 PFU/ml of Influenza B virus by plaque assay. A rapid and sensitive detection method of a one-tube with multiplex RT-PCR capable of identifying more than one viral template as well as synchronizing reverse transcription and PCR had the potential to produce considerable savings of time and cost effectiveness in the diagnostic laboratory.
Conserved Sequence ; Cost-Benefit Analysis ; Electrophoresis ; Hemagglutinins ; Herpesvirus 1, Cercopithecine ; Humans* ; Income ; Influenza B virus ; Influenza, Human* ; Nucleocapsid ; Orthomyxoviridae* ; Polymerase Chain Reaction* ; Respiratory Syncytial Virus, Human* ; Respiratory Syncytial Viruses ; Reverse Transcription* ; Sensitivity and Specificity

No abstract available.

Cutarieous manifest,ations and systemic complications were observed in 521 patient., with diabetes mellitus. The results were as follows: Total 70, 8% of patients had complications', In 16. 5%, cutaneous manifestation were observed. Systemic complications were observed in 27 6%, Both eutaneous manifestations and systemic complications were observed in 26 7% 2 The cutaneous mariifestations observed in 43 2%, were cutaneous infection, pruritus, shin spot, diabetic foit, peripheral edema, diahetic bulla, foot gangrene and rutieosis in the order of frequency, 3, The cutaneous manifestations were much more observed in patients with systemic complications than without them(p<0 05), and with longer duration more than 10 years history, 4. It seems to be no relationship between the cutancous manifestations and fasting blood sugar level.
Blood Glucose ; Diabetes Mellitus* ; Edema ; Fasting ; Foot ; Gangrene ; Humans ; Pruritus ; Statistics as Topic*

OBJECTIVE: Disc displacement may affect the joint space narrowing between condyle head and glenoid fossa. This study was designed to evaluate the correlation between the joint space change and the directions of disc displacement. STUDY DESIGN: Two hundreds temporomandibular joints MR images of TMD patients (170 joints) and asymptomatic volunteers (30 joints) were evaluated for this purpose. Anterior disc displacement was divided into 3 stages (normal, little to mild, and moderate to severe displacement) based on sagittal images. And sideways displacement was classified as 3 categories (center, medial and lateral displacement) based on coronal images, then joint spaces were measured at medial, central and lateral parts of condyle head on coronal MR images, respectively. The joint spaces of 7 groups divided according to the severity and the direction of disc displacement were compared. RESULTS: The reduction of the joint space was affected by sideways disc displacement at the opposite side of the condyle head, except the cases accompanied with severe anteriorly and laterally displaced disc. CONCLUSION: The sideways disc displacement affected on the opposite side temporomandibular joint space width.
Head ; Humans ; Joints* ; Magnetic Resonance Imaging ; Temporomandibular Joint* ; Volunteers

BACKGROUND: Dutasteride is an inhibitor of both types I and II 5 alpha-reductase and was approved in Korea in April 2004. This post-marketing surveillance was to assess the safety of dutasteride in Korean patients with benign prostate hyperplasia in real life and to elucidate the risk factors related adverse events. METHODS: From December 2004 to January 2010, 3,977 patients were enrolled by 184 urologists. According to post-marketing surveillance regulation, patients were enrolled consecutively. Patients administered dutasteride at least once were included in safety assessment. The incidences of any adverse events and serious adverse events were evaluated. Multiple logistic regression method was used to identify risk factors related to adverse events. RESULTS: The safety assessment included 3,870 patients with the mean age of 67.3 years. The incidence of adverse events was 3.8 %. The most frequent adverse event was impotence (75 cases, 1.9 %), libido decrease (49 cases, 1.3 %), ejaculation disorder (30 cases, 0.8 %), and gynecomastia (5 cases, 0.1 %). The incidence of unexpected adverse events was 0.5 % and cerebral infarction, lung cancer, pulmonary embolism, and diarrhea were reported as serious adverse events. CONCLUSION: In this survey, impotence was the most frequently reported adverse events. Dutasteride was well tolerated in Korean patients with benign prostate hyperplasia. These results updated the safety information and would provide important additional information for prescribers.
Azasteroids ; Cerebral Infarction ; Cholestenone 5 alpha-Reductase ; Diarrhea ; Drug Toxicity ; Dutasteride ; Ejaculation ; Erectile Dysfunction ; Gynecomastia ; Humans ; Hyperplasia ; Incidence ; Korea ; Libido ; Logistic Models ; Lung Neoplasms ; Male ; Prostate ; Pulmonary Embolism ; Risk Factors

Noise is not only affecting the ear and the auditory cortex locally, but its influence is widely spread throughout the brain structures, e. g., the reticular formation, the brain stem nuclei or the subcortical forebrain area. Hence, any of the organism's activities can be hindered or stimulated by noise. High noise is a stressor and the catecholamine level can be used both as a stress marker and as an indicator of modified sympathetic nervous system activity. Several recent studies have found that the urinary excretion of catecholamines is increased due to high noise intensity, especially unexpectedly high and long lasting noise. The present study was conducted in order to examine the effects of noise stress on urinary excretion of catecholamines in rats and humans. Rats were exposed to 90 dB noises for 10, 30, and 60 minutes, 3 and 12 hours. 24 hour urinary samples were collected and the catecholamines were extracted by alumina and analyzed by HPLC-ECD. Catecholamine levels increased with time of exposure up to 60 minutes: norepinephrine concentration at 60 min of noise=1.038 ng/ml, epinephrine=0.636 ng/ml. Urine catecholamines of blue collar workers exposed to 90 dB of noise at the workplace were collected between 2 and 4 p.m. and compared to that of white collar workers exposed to 70 dB. Mean norepinephrine level of the blue collar workers was 0.89 ng/ml(+/-0.25), epinephrine 0.24 ng/ml(+/-0.09), and that of the white collar workers 0.48 ng/ml(+/-0.12), epinephrine 0.19 ng/ml(+/-0.05). It was concluded that noise acts as a stressor and increases the catecholamine levels in both rats and humans.
Aluminum Oxide ; Animals ; Auditory Cortex ; Brain ; Brain Stem ; Catecholamines ; Ear ; Epinephrine ; Humans ; Noise* ; Norepinephrine ; Prosencephalon ; Rats ; Reticular Formation ; Sympathetic Nervous System

No abstract available.
Nasal Surgical Procedures*

No abstract available.
Neck*