1.A case of pseudoaneurysm of the sphenopalatine artery followingpanfacial bone fracture.
Hyung Joo KIM ; Min Ho SHIN ; Byung Do SUH
Korean Journal of Otolaryngology - Head and Neck Surgery 1992;35(6):930-935
No abstract available.
Aneurysm, False*
;
Arteries*
;
Fractures, Bone*
2.A Case Report of Takayaeu's Arteritis Associated with, a Retinopathy.
Jin Hwal SUH ; Byung Joo YOON ; Hyung Jeon KIM
Journal of the Korean Ophthalmological Society 1989;30(5):829-833
The authors have experienced a case of Takayasu's arteritis associated with Takayasu's retinopathy which is confirmed by aortography and fluorescent angiography in a 14 year old female.
Adolescent
;
Angiography
;
Aortography
;
Arteritis*
;
Female
;
Humans
;
Takayasu Arteritis
3.The effect of verapamil and urokinase on hepatocyte function and systemic hemodynamics in acute liver ischemia.
Bo Yang SUH ; Dong Kwun SUH ; Joo Hyung LEE ; Woo Seok SUH ; Ho Yeol YE ; Hong Jin KIM ; Min Chul SHIM ; Koing Bo KWUN ; Dong Il PARK
Journal of the Korean Surgical Society 1993;44(1):11-23
No abstract available.
Hemodynamics*
;
Hepatocytes*
;
Ischemia*
;
Liver*
;
Urokinase-Type Plasminogen Activator*
;
Verapamil*
4.A case of pregnant woman with acute promyelocytic leukemia.
Joo Won CHOI ; Seung Sik SUH ; Eun Sin CHUNG ; Hyung Yeol LEE ; Young Hye LEE ; Choon Hee LEE
Korean Journal of Obstetrics and Gynecology 1991;34(7):1021-1026
No abstract available.
Female
;
Humans
;
Leukemia, Promyelocytic, Acute*
;
Pregnant Women*
5.A Case of Amitraz Insecticide Intoxication after Ingestion of Large Amount.
Journal of The Korean Society of Clinical Toxicology 2008;6(1):52-56
Amitraz is used as farm-animal insecticide. Its side effects in humans are related to its pharmacological activity on alpha 2-adrenergic receptors. The case describes a previously healthy 46-year-old woman who intentionally ingested approximately 250mL of liquid amitraz. She presented with vomiting, altered mental status, miosis, dry mouth, hypopnea, metabolic and respiratory acidosis, hypotension, hypothermia, polyuria, metabolic acidosis, elevated serum aminotransferase and abdominal distension. Supportive treatments including mechanical ventilation, hydration, dopamine infusion, bicarbonate infusion and gastric decompression resulted in improvement. By hospital day 3, she recovered with resolution of abdominal distension. It is paramount to recognize amitraz poisoning when apesticide-intoxicated patient presets with signs and symptoms consistent with organophosphate intoxicated patients but with greater alpha 2-adrenergic related symptoms such as decreased bowel motility and xerostomia.
Acidosis
;
Acidosis, Respiratory
;
Decompression
;
Dopamine
;
Eating
;
Female
;
Humans
;
Hypotension
;
Hypothermia
;
Intention
;
Middle Aged
;
Miosis
;
Mouth
;
Polyuria
;
Respiration, Artificial
;
Toluidines
;
Vomiting
;
Xerostomia
6.Effects of Cyclo-His-Pro-enriched yeast hydrolysate on blood glucose levels and lipid metabolism in obese diabetic ob/ob mice.
Eun Young JUNG ; Yang Hee HONG ; Chung PARK ; Hyung Joo SUH
Nutrition Research and Practice 2016;10(2):154-160
BACKGROUND/OBJECTIVES: We examined the hypoglycemic and anti-hyperlipidemic effect of yeast hydrolysate (YH) enriched with Cyclo-His-Pro (CHP) in the C57BL/6J ob/ob mouse model. MATERIALS/METHODS: Mice were separated into 4 groups (8 mice/group) on the basis of blood glucose and body weight: WT control, lean mice given vehicle; ob/ob control, ob/ob mice given vehicle; YH-1, ob/ob mice given 0.5 g/kg of YH; YH-2, ob/ob mice given 1 g/kg of YH. YH in saline or vehicle was administered orally in the same volume every day for 3 weeks. RESULTS: Mice treated with YH (0.5 and 1 g/kg) for 3 weeks displayed a significant reduction in overall body weight gain and perirenal and epididymal adipose tissue weight compared to the ob/ob control group. Additionally, high-density lipoprotein (HDL) cholesterol, glucose, and atherogenic indexes were significantly decreased in the blood of YH-1 and YH-2 groups compared to the ob/ob control. In ob/ob mice, YH administration significantly improved glucose tolerance and blood insulin levels. These data indicate that YH treatment produces potent hypoglycemic and anti-hyperlipidemic effects by controlling body weight, fat mass, blood lipid, insulin levels, and glucose tolerance. CONCLUSION: YH could potentially be used as a treatment option for diabetes and hyperlipidemia. The CHP-enriched YH may be a promising strategy in the development of hypoglycemic peptide nutraceuticals.
Adipose Tissue
;
Animals
;
Blood Glucose*
;
Body Weight
;
Cholesterol
;
Diabetes Mellitus
;
Dietary Supplements
;
Glucose
;
Hyperlipidemias
;
Insulin
;
Lipid Metabolism*
;
Lipoproteins
;
Mice*
;
Yeasts*
7.Partial Purification and Characterization of 41 kDa Serine Proteinase from Culture Filtrate of Trichophyton tonsurans.
Jae Il YOO ; Yeong Seon LEE ; Yeon Hwa CHOI ; Hyung Yeul JOO ; Bong Su KIM ; Soon Bong SUH
Journal of the Korean Society for Microbiology 1999;34(3):303-310
Dermatophytes infect the human hair, skin, nail and cause the dermatophytosis. The extracellular and intracellular proteinases of the dermatophytes commonly occur in the genus Trichophyton like T. rubrum, T. mentagrophytes, and T. granulosum. These enzymes play a prominent role in growth, multiplication and infection of the host tissue. Extracellular proteinases have been purified from the species of Trichophyton and Microsporum. We purified the proteinase partially from the culture filtrate of the Trichophyton tonsurans through Mono-Q and Superose 12 column and investigated its biochemical and enzymatic characters. The molecular size of the proteinase was estimated to be 41 kDa by SDS-PAGE. And pI was 3.2. The optimal temperature and pH for an enzymatic activity were 27C and 7.5, respectively. The purified porteinase degraded the keratin, bovine serum albumin, hemoglobin. The serine proteinase inhibitor like PMSF and DFP inhibited the proteolytic activity of the purified enzyme whereas the cysteinase inhibitor did not. These results demonstrated that the purified proteinase is a serine proteinase and can contribute the tissue invasion.
Arthrodermataceae
;
Electrophoresis, Polyacrylamide Gel
;
Hair
;
Humans
;
Hydrogen-Ion Concentration
;
Isoflurophate
;
Microsporum
;
Peptide Hydrolases
;
Serine Proteases*
;
Serine*
;
Serum Albumin, Bovine
;
Skin
;
Tinea
;
Trichophyton*
8.Clinico-pathologic studies on pelvic mass.
Eun Shin CHUNG ; Joo won CHOI ; Seung Sik SUH ; Ji Won GONG ; Hyung Yeol LEE ; Young Hye LEE
Korean Journal of Obstetrics and Gynecology 1992;35(10):1509-1515
No abstract available.
9.Lymph Node Metastases in Thyroid Carcinomas: CT Diagnosis.
Ji Seon JOO ; Hyung Jin KIM ; Kyung Jin KANG ; Young Kuk CHO ; Myung Kwan LIM ; Chang Hae SUH
Journal of the Korean Radiological Society 2001;45(6):581-588
PURPOSE: To determine the usefulness of CT for diagnosing metastases to primary and secondary echelon lymph nodes (LNs) and to investigate various CT findings of metastatic LNs in thyroid carcinomas. MATERIALS AND METHODS: We retrospectively reviewed the CT and histologic findings in 59 patients with thyroid carcinomas who had undergone thyroidectomy and neck dissection. Primary echelon LNs (Level VI) were removed by central neck dissection in all patients, and in 21, a total of 136 levels of secondary echelon LNs (Level II-V) were excised away by lateral neck dissection. CT criteria of metastatic LNs included large size, significant homogeneous enhancement, calcification, and cystic change. We evaluated the ability of CT to detect primary and secondary echelon LN metastasis and tried to determine which CT features were useful for the diagnosis of LN metastasis. RESULTS: Histologically, LN metastasis was found in 31 (53%) of 59 patients, including 30 with metastasis to primary echelon LNs. Of the 136 levels of secondary echelon LNs resected in 21 patients, 44 were found at histology to harbor metastatic foci. The sensitivities, specificities, positive and negative predictive values, and accuracies of CT in the diagnosis of metastasis to primary and secondary echelon LNs, respectively, were 27% and 93%, 100% and 93%, 100% and 87%, 57% and 97%, and 63% and 93%. While all secondary echelon LNs with at least one of the following CT criteria-large size (n=19), cystic or necrotic change (n=14), or calcifications (n=8)-were histologically proven to be metastatic, six (24%) of 25 such LNs with a sole sign of significant enhancement at CT were found to be due to reactive lymphadenopathy. CONCLUSION: Although CT was unable to detect metastasis to primary echelon LNs, it was useful in the detection of secondary echelon LN involvement. Large size, cystic change, and calcification are considered highly reliable signs of metastatic LNs.
Diagnosis*
;
Humans
;
Lymph Nodes*
;
Lymphatic Diseases
;
Neck Dissection
;
Neoplasm Metastasis*
;
Retrospective Studies
;
Thyroid Gland*
;
Thyroid Neoplasms*
;
Thyroidectomy
10.Clinical Observation on Ruptured Aneurysm of the Sinus of Valsalva.
Seung Jae JOO ; Kwang Gon KOH ; Yu Ho KIM ; Young Bae PARK ; Yun Shik CHOI ; Jeong Don SEO ; Young Woo LEE ; Jae Hyung PARK ; Kyung Phill SUH
Korean Circulation Journal 1987;17(1):149-158
From May, 1975 to August, 1986, we experienced 21 patients with ruptured aneurysm of the sinus of Valsalva. 1) Their ages ranged from 15 to 52 years with a mean age of 26.7 years, and 14 patients were male and 7 patients were female. Among 18 cases of which aneurysms occurred on the right sinus of Valsalva, 15 cases (83%) ruptured into the right ventricle, 1 case (6%) ruptured into the right atrium and 2 cases (11%) ruptured into the pulmonary artery. All 3 cases of which aneurysms occurred on the noncoronary sinus ruptured into the right atrium. 2) Clinical symptoms consisted of dyspnea (95%), palpitation (81%), chest pain (43%), orthopnea (33%), cough (14%), hemoptysis (5%), oliguria (5%), and fever (5%). In all patients continuous heart murmur was audible. Hepatomegaly (48%), pulmonary basal rale (14%), and pretibial pitting edema (19%) were also observed. 3) In all patients diagnosis was made with cardiac catheterization and angiography, and confirmed by operation excetpt one case. 4) Among 20 patients who had been performed corrective surgery, ventricular septal defect was observed in 16 patients (85%), aortic insufficiency in 5 patients (25%), pulmonary infundibular stenosis in 1 patient (5%), patent foramen ovale in 1 patient (5%), and tricuspid insufficiency in 1 patient (5%). Ventricular septal defect was observed in all 16 patients whose aneurysms of the right coronary sinus of Valsalva ruptured into the right ventricle and the pulmonary artery. 5) All patients survived operation, and no postoperative complication was found except 1 patient to whom reoperation was performed because of postoperative aortic insufficiency and detachment of the patch closure for ventricular septal defect. There was symptomatic improvement in all patients.
Aneurysm
;
Aneurysm, Ruptured*
;
Angiography
;
Cardiac Catheterization
;
Cardiac Catheters
;
Chest Pain
;
Coronary Sinus
;
Cough
;
Diagnosis
;
Dyspnea
;
Edema
;
Female
;
Fever
;
Foramen Ovale, Patent
;
Heart Atria
;
Heart Murmurs
;
Heart Septal Defects, Ventricular
;
Heart Ventricles
;
Hemoptysis
;
Hepatomegaly
;
Humans
;
Male
;
Oliguria
;
Postoperative Complications
;
Pulmonary Artery
;
Pulmonary Subvalvular Stenosis
;
Reoperation
;
Respiratory Sounds
;
Sinus of Valsalva*