No abstract available.
Aneurysm, False* ; Arteries* ; Fractures, Bone*

Myocarditis is defined as the myocardial inflammation caused by various infectious agents (such as virus, rickettsia , bacteria, protozoa, fungus and parasites). The clinical manifestations of myocarditis ranges from the asymptomatic state due to focal inflammation to fulminant fatal congestive heart failure secondary to diffuse myocardial involvement. Clinically, in some cases, it may simulate an acute myocardial infarction. We experienced a case of acute fulminant myocarditis that presented as acute myocardial infarction initially, and then progressed into and recovered from congestive heart failure and multiorgan failure.
Asymptomatic Diseases ; Bacteria ; Estrogens, Conjugated (USP)* ; Fungi ; Heart Failure* ; Inflammation ; Myocardial Infarction ; Myocarditis* ; Rickettsia

Osteopetrosis is a very rare bone dysplasia characterized by failure of resorption and persistence of calcified chondroid and primitive bone. In 1904 Albers-Schonberg first described the radiological appearance of marble bone. This is named osteopetrosis by Karshner in 1926. A fulminating form is manifested from birth in which fractures and deformity, hydrocephalus and cranial nerve palsies lead to early death from intractable anemia and intercurrent infection. In other cases the stigmata are delayed until later childhood, when retardation of growth and of mental and sexual development occurs, and not infrequently accompanied by rickets, dental caries and osteomyelitis. We have experienced a familial osteopetrosis, father and three siblings, which was thought to be a autosomal dominant inheritance. One of those family, 20 years old man, has been complained of anemia and low back pain without radiating pain to the lower extremities. The other 3 patients has not been complained of any other clinical symptoms. But X-Ray examination of the entire skeletal survey of those members of the family have revealed the uniform opacity of long bones and flat bones.
Anemia ; Bone Diseases, Developmental ; Calcium Carbonate ; Christianity ; Clothing ; Congenital Abnormalities ; Cranial Nerve Diseases ; Dental Caries ; Fathers ; Humans ; Hydrocephalus ; Low Back Pain ; Lower Extremity ; Osteomyelitis ; Osteopetrosis ; Parturition ; Rickets ; Sexual Development ; Siblings ; Wills

Synovial sarcoma is an uncommon, highly malignant soft tissue tumor usually arising from the synovial lining of a joint, bursa and tendon sheath. Occurence in muscle fascia is extremely rare. We present a case of synovial sarcoma of the left calf muscle fascia, which was confirmed by microscopically sarcomatous growth of spindle cells and irregular small multiloculation. Above knee amputation was done.
Amputation ; Fascia ; Joints ; Knee ; Sarcoma, Synovial ; Tendons

The Ankle joint is a modified complex hinge joint which plays an importnat role in weight bearing, walking and standing. Injuries about the ankle joint cause destruction of not only bony architecture but also the ligament and soft tissue components. We performed arthrography in 52 cases of ankle fracture. The Result obtained from this study was as follow; The ligament & interosseous membrane injuries were more severe, when fracture of lateral malleolus was occured higher level than ankle joint.
Ankle Fractures ; Ankle Joint ; Ankle ; Arthrography ; Clinical Study ; Joints ; Ligaments ; Membranes ; Walking ; Weight-Bearing

No abstract available.
Lymphangioma*

PURPOSE: To seek the role of nuclear factor kappa B (NF-kB) on the corneal epithelial cell death after ultraviolet (UV) irradiation. METHODS: Human corneal epithelial cells transfected by Simian Virus 40 were used in this study. UVB(312 nm) located at 10cm distance from bottom (0.6 mW/cm2 ) was irradiated for 10, 20, 30, and 40 seconds. To measure the cytotoxicity, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) method was used. Translocation of NF-KB was examined by immunocytochemistry with anti NF-K B p65 antibody and Electrophoretic Mobility Shift Assay (EMSA). To confirm the role of NF-KB , sulfasalazine, a specific inhibitor of NF-KB (0.5 mmole), was pretreated for 30 minutes before irradiatrion, and cytotoxicity and translocation of NF-KB was evaluated. RESULTS: UV irradiation resulted in a significant decrease in viability of cultured human corneal epithelial cells, especially after 20 second duration. When HCECs were irradiated with UVB, the translocation of N F -KB was observed in immunocytochemistry. These translocation was peaked 2 hours after UV irradiation in EMSA. In HCECs pretreated with sulfasalazine, either the cellular death or the translocation of NF-KB was blocked. CONCLUSION: UV irradiation can translocate NF-KB on the cultured human corneal epithelial cells. The cellular death after UV irradiation was blocked by sulfasalazine, a potent inhibitor of translocation of NF-KB. These findings suggest that NF-KB plays an important role in cellular death after UV irradiation.
Electrophoretic Mobility Shift Assay ; Epithelial Cells* ; Humans ; Immunohistochemistry ; NF-kappa B ; Simian virus 40 ; Sulfasalazine

Orbital varix is a relatively rare disease that causes exophthalmos due to increase of cerebral venous pressure. We experienced a forty-two-year-old male patient, who complained of intermittent exophthalmos and blurred vision. The diagnosis was based on clinical manifestation and various radiologic studies including computed tomography(CT), venography, and magnetic resonance imaging(MRI). MRI is a useful and safe diagnostic study through which we could observe the orbital varix and assess the relationship between the varix and the orbital structure. In this case, the varix is huge and attached to superior rectus muscle. There being many surgical risks, he has been followed up without surgical treatment and educated to modify the life pattern for prevention of increase of carotid venous presure.
Diagnosis ; Exophthalmos ; Follow-Up Studies* ; Humans ; Magnetic Resonance Imaging ; Male ; Orbit* ; Phlebography ; Rare Diseases ; Varicose Veins* ; Venous Pressure

p53 suppressor gene expression and protein production increases in response to DNA damage and the subsequent cell cycle prolongation permits DNA repair or, in the severe cases, leads to apoptosis. These concepts led us to investigate the expression of p53 as a potential key regulator of DNA repair in the cornea after mechanical-and chemical-induced injury. Mechanical-induced injury was performed by denuding a4mmdiameter area of the central epithelium from the corneas of Sprague Dawley rats. Chemical-induced injury was performed by applying a 3.5 mmdiameter filter paper disc of saturated n-heptanol to the cornea. Samples were collected on the 1st 3rd and 7th day of treatment. We performed immunohistochemistry and Western blot analysis on corneal buttons. Control group did not receive any treatment. The immunohistochemical analysis demonstrated that p53 is localized in the anterior stromal keratocytes. Western blot analysis indicated p53 bandsin the lanes of the mechanically and the chemically injured corneas. Our results suggest that injury to the corneal epithelium triggers the activation of p53.
Apoptosis ; Blotting, Western ; Cell Cycle ; Cornea* ; DNA Damage ; DNA Repair ; Epithelium ; Epithelium, Corneal ; Genes, Suppressor* ; Heptanol ; Immunohistochemistry ; Rats, Sprague-Dawley

PURPOSE: To evaluate the effect of a capsular tension ring (CTR) on the tilting and decentration of intraocular lenses (IOLs) after cataract surgery. METHODS: Cataract surgery was performed on both eyes of twenty patients ranging from 57 to 75 years old. Forty eyes were divided into two groups based on whether or not a CTR (Lucid Korea, Korea) was implanted. Each patient received a CTR in one eye. All IOLs (MA60BM, Acrysof R , Alcon) were implanted into the capsular bag after a continuous curvilinear capsulorhexis smaller than the optic size of the IOL, and phacoemulsification was performed. The extent of tilting and decentration of the IOLs were measured with the EAS-1000 anterior eye segment analysis system at 7, 30, and 60 days after surgery. RESULTS: IOL decentration decreased to a statistically significant extent in the eyes implanted with both IOL and CTR, versus those with IOL only. The values of CTR+IOL group were: 0.38+/-0.16 mm at 7 days, 0.43+/-0.15 mm at 30 days, and 0.42+/-0.17 mm at 60 days. The IOL-only group values were: 0.49+/-0.11mm at 7 days, 0.53+/-0.14 mm at 30 days, and 0.57+/-0.16 mm at 60 days. IOL tilting also decreased significantly in the IOL+CTR group compared to the IOL-only group. The CTR+IOL values were: 2.22+/-0.46 degrees at 7 days, 2.36+/-0.50 degrees at 30 days, and 2.47+/- 0.40 degrees at 60 days. The IOL-only group values were: 3.14+/-0.65 degrees at 7 days, 2.91+/-0.67 degrees at 30 days, and 3.06+/-0.56 degrees at 60 days. CONCLUSIONS: These results indicate that the CTR reduces undesirable post-surgical movement of the IOL for at least 60 days.
Aged ; Anterior Eye Segment ; Capsulorhexis ; Cataract* ; Humans ; Korea ; Lenses, Intraocular* ; Phacoemulsification