No abstract available.
Transplants

No abstract available.
Animals ; Rats ; Sciatic Nerve ; Transplants

Split hand split foot(SHSF) is a rare human developmental defect characterized by mi-ssing digits, fusion of remaining digits, and a deep median cleft in the hands and feet. Cy-togenetic studies of deletions and translocations associated with this disorder have indicated that an autosomal dominant split hand/split foot locus maps to 7q21-q22. We have experienced a case of ectrodactyly in a 25-year-old primigravida woman and her baby and reported out our experience with a review of related literature.
Adult ; Female ; Fetus* ; Foot ; Hand ; Human Development ; Humans

No abstract available.
Pancreatitis*

The purpose of present study was to assess which parameters influence human oocyte zona pellucida(ZP). Zone pellucida thickness was evaluated in 124 oocytes of 16 cycles IVF-ET with intracytoplasmic sperm injection(ICSI) between July 1995 and October 1995 at the department of obstetrics and Gynecology, Yonsei university, Wonju Christian Hospital. The zone pullucida thickness was 17.7+/-2.0micronm(mean+/-SD) for 107 metaphase II oocy- tes. The zona pullucida thickness was singinficantly different according to maximum estr- adiol(E2) value ; The mean thickness of Zona pellucida was thinner below 2000 pg/ml of E2 value than that above 2001 pg/ml of E2 value(p<0.05). And when the metaphase II oocytes was cultured for 3 days, the mean thickness of Zona pellucida was thinner than that of metaphase II oocytes whether fertilization or not(p<0.01, p<0.03). But the Zona pellucida thickness was not significantly different from the age of women and the oocyte maturation status(p>0.05).
Female ; Fertilization ; Gangwon-do ; Gynecology ; Herpes Zoster* ; Humans* ; Metaphase ; Obstetrics ; Oocytes ; Sperm Injections, Intracytoplasmic ; Spermatozoa ; Zona Pellucida*

PURPOSE: To investigate the esophagographic findings of early esophageal cancer(EEC), and to compare thesewith the pathologic results, and to thus determine the most useful method of esophagography for the detection ofEEC. MATERIALS AND METHODS: We examined 18 patients(M : F = 16 : 2) with pathologically proven EEC ; 17 cases weresquamous cell carcinoma and one was adenocarcinoma. Tumor size, shape and location were evaluated byesophagography and the findings were compared with the pathologic results. RESULTS: The tumors were 0.5-7 cm insize ; all except two were smaller than 4cm. Twelve were located in the middle esophagus, five cases in the loweresophagus and one case in the upper esophagus ; in ten cases, the margin was ill-defined. Esophagography showedthat eight cases were of the superficial depressed type, seven were the superficial elevated type, and three werethe tumorous type. All 18 cases were detected by double contrast study, but mucosal relief study and bariumfilling study revealed only ten and eight cases, respectively ; for the detection of EEC, double contrast studywas thus the most useful. CONCLUSION: EEC was commonly demonstrated in the middle esophagus with an ill-definedmargin ; it was of the superficial depressed or elevated type. For the detection of EEC, double contrast study wasthe most useful.
Adenocarcinoma ; Esophageal Neoplasms* ; Esophagus ; European Union

Sex identification may be described in terms of some characteristics. Any individual with testicular formation and contraindiction of any of the anatomical criteria of sex may be considered as a male pseudohermaphrodite. Most of them have genitalia that are more feminine than masculine, are best raised as females. We report a 26-year-old male pseudohermaphrodite who was phenotypically female with amenorrhea, little breast development and little sexual hair. For treatment, multidisciplinary team approach including pubic hair transplantation is needed to enhance self-image and confidence in intersexuality.
46, XY Disorders of Sex Development* ; Adult ; Amenorrhea ; Breast ; Disorders of Sex Development ; Female ; Genitalia ; Hair* ; Humans ; Male*

Human uterus has been known as a immune privileged site for the product of conception. At the feto-maternal interface, Fas system is a underlying main mechanism of maternal immune acceptance. To date, the TRAIL (TNF-related apoptosis-inducing ligand) system is known to be another pivotal mechanism. OBJECTIVE: To clarify the protein expression of TRAIL ligand and receptors in the normal and pathologic (preeclampsia, hydatidiform mole) placenta, chorioamnion, decidua. METHODS: we investigated the expression of TRAIL system in the above-mentioned tissues by using Western Hybridization. RESULTS: All tissues expressed TRAIL ligand and only a DcR2 among TRAIL receptors (DR4, DR5, DcR1, DcR2). CONCLUSION: we demonstrated the expression of TRAIL ligand and DcR2 protein at the feto-maternal interface of the normal and pathologic pregnancies. Further study regarding the expression of other receptors and quantitative analysis between normal and pathologic pregnancies should be followed.
Apoptosis* ; Decidua ; Female ; Fertilization ; Gestational Trophoblastic Disease* ; Humans* ; Placenta ; Pregnancy ; Receptors, TNF-Related Apoptosis-Inducing Ligand ; Uterus

Intramural pregnancy is one of the rarest forms of ectopic pregnancy. The pathologic diagnosis of the intramural ectopic pregnancy requires that the myometrium surrounds the products of conception separated from the endometrial cavity or fallopian tubes. Because the early diagnosis is very difficult, most cases are found after the onset of complications such as a uterine rupture or hemoperitoneum. The previous histories of curettage, cesarean section, myomectomy, salpingectomy and manual removal of the placenta are known as possible etiology of the intramural pregnancy. We have recently experienced a case of intramural pregnancy after 10 times of curettages and are reporting with a brief review of the literatures.
Animals ; Cesarean Section ; Curettage ; Diagnosis ; Early Diagnosis ; Fallopian Tubes ; Female ; Fertilization ; Hemoperitoneum ; Mice ; Myometrium ; Placenta ; Pregnancy* ; Pregnancy, Ectopic ; Salpingectomy ; Uterine Rupture

OBJECTIVE: The authors have aimed to compare the efficacy of the computed tomography with other study methods, and to investigate if replacement by computed tomography is possible METHODS: From January 1998 to December 2002, 203 cervical cancer patients underwent pre-staging studies including computed tomography. The positive predictive values, negative predictive values, sensitivity, specificity of each method of study were compared. RESULTS: 1. Compared computed tomography with intravenous pyelonephrography. Each values of computed tomography for hydronephrosis or non visualization of kidney were sensitivity 91.7%, specificity 97.8%, positive predictive values 84.6%, negative predictive values 98.9%. 2. Compared computed tomography with cystoscopy. Each values of computed tomography for bladder invasion were sensitivity 90%, specificity 95.8%, positive predictive values 52.9%, negative predictive values 99.4%. 3. Compared computed tomography with sigmoidoscopy. Each values of computed tomography for rectal invasion were sensitivity 80%, specificity 94.4%, positive predictive values 26.6%, negative predictive values 99.4%. CONCLUSION: Rather than routine examination for staging of invasive cervical cancer in all patients, it is more ideal to first take a non invasive technique. then perform on intravenous pyelonephrography, cystoscopy and sigmoidoscopy only in patient showing positive findings of hydronephrosis or non visualization of kidney, bladder or rectal invasion on computed tomography.
Cervix Uteri* ; Cystoscopy ; Female ; Humans ; Hydronephrosis ; Kidney ; Sensitivity and Specificity ; Sigmoidoscopy ; Urinary Bladder ; Uterine Cervical Neoplasms