No abstract available.
Animals ; Bacteria* ; Carcinoma, Lewis Lung* ; Lactic Acid* ; Mice* ; Sarcoma 180* ; Sarcoma*

No abstract available.
Histiocytoma*

PURPOSE: Vascular endothelial growth factor (VEGF) is highly expressed in the airways of asthmatic patients. Asthmatic children are commonly exposed to parental smoking. We investigated the effect of environmental tobacco smoking (ETS) on VEGF levels in induced sputum of asthmatic children. METHODS: Sixty-nine asthmatic children were enrolled, who were hospitalized in the Pediatric Department of Korea University Hospital for acute asthma exacerbation. We interviewed their parents to assess ETS history with a questionnaire. We measured VEGF levels in induced sputum from asthmatic children by enzyme-linked immunosorbent assay, and we also measured the concentrations of sputum ECP by radioimmunoassay. We compared sputum levels of VEGF and ECP between an ETS group and a non-ETS group. RESULTS: Of the 69 cases, 45 were in the non-ETS group and 24 were in the ETS group. The ETS group showed higher sputum VEGF levels than did the non-ETS group (P=0.001). Serum IgE levels were not related to the sputum levels of VEGF in the ETS group, and there was no association between serum levels of ECP and sputum levels of VEGF. CONCLUSION: When asthmatic children were exposed to family smoking, higher levels of VEGF were measured in their sputum. It seems that environmental smoking aggravates allergic airway inflammation. We suggest that parents of asthmatic children should make all efforts to stop smoking.
Asthma ; Child* ; Enzyme-Linked Immunosorbent Assay ; Humans ; Immunoglobulin E ; Inflammation ; Korea ; Parents ; Surveys and Questionnaires ; Radioimmunoassay ; Smoke* ; Smoking* ; Sputum* ; Vascular Endothelial Growth Factor A*

No abstract available.
Citrobacter freundii* ; Citrobacter* ; Osteomyelitis*

No abstract available.
Citrobacter freundii* ; Citrobacter* ; Osteomyelitis*

The majority of ptients with ischemic heart disease such as angina pectoris and myocardial infarction have coronary atherosclerosis as a underlying cause. However, in unusual conditions such as variant angina, aortic valvular heart disease, hypertrophic cardiomyopathy, vasculitis, hypercoagulable states, coronary atherosclerosis is not the cause. Polycythemia vesa is a myeloproliferative disease characterized by infrequent thromboembolic complications such as ischemic heart disease. We report a case of polycythemia vera presenting with angina pectoris without coronary artery stenosis with the review of the literature.
Angina Pectoris* ; Cardiomyopathy, Hypertrophic ; Coronary Artery Disease ; Coronary Stenosis* ; Coronary Vessels* ; Heart Valve Diseases ; Myocardial Infarction ; Myocardial Ischemia ; Polycythemia Vera* ; Polycythemia* ; Vasculitis

Tisomy 10p syndrome is a rarely reported chromosomal abnormality with distinct craniofacial anomalies, severe growth and psychomotor retardation, osteoarticular anomalies, and organ malformations. Most of reported cases were due to translocation of 10p to the other chromosome. Rare causes are tandem duplication, maternal pericentric inversion, isochromosome formation. We experienced newborn infant with craniofacial anomaly, hypospadias and extra vertebra and rib. The characteristic craniofacial anomalies were frontal bossing, wide opened fontanel and suture line, sparse eyebrow, turtle beak mouth, Cytogenic analysis showed 46, XY, rec(10) dup(10p) inv (10)(p11.2q26.1). Karyotype of the father was normal(46, XY). However, karyotype of the mother showed 46, XX, inv(10)(p11.2q26.1). Therefore, chromosome 10 recombination resulting from a maternal pericentric inversion formed trisomy 10p. We report rare chromosome abnormality syndrome, trisomy 10p, with brief review.
Animals ; Beak ; Chromosome Aberrations ; Chromosomes, Human, Pair 10 ; Eyebrows ; Fathers ; Female ; Humans ; Hypospadias* ; Infant, Newborn ; Isochromosomes ; Karyotype ; Male ; Mothers ; Mouth ; Recombination, Genetic ; Ribs ; Spine ; Sutures ; Trisomy* ; Turtles

Shiitake (Lentinus edodes) is a kind of mushroom which is cooked and eaten as a food in Chinese, Japanese and Korean meals. It is nowadays the second most commonly produced edible mushroom in the world. In 1985, a case characterized by itchy skin eruptions after the ingestion of raw shiitake mushrooms was reported and was termed as toxicodermia. Here we report five cases of shiitake dermatitis which developed after ingestion of raw or cooked shiitake mushrooms. All patients complained of severe itching and showed linear grouped erythematous papules after scratching(Kobner phenomenon). To our knowledge, this is the first report of shiitake dermatitis in the Korean literature.
Agaricales ; Asian Continental Ancestry Group ; Dermatitis* ; Eating ; Humans ; Meals ; Pruritus ; Shiitake Mushrooms ; Skin

No abstract available.
Autoantibodies* ; DNA*

Tuberculosis of the thyroid gland is extremely rare, with only a few reported cases in the recent literature. The diagnosis is based entirely upon the histological picture of the tubercle, which consists of aggregates of mononuclear epithelial cells, giants cells, and a border of lymphocytes. Tuberculosis may involve the thyroid gland in two main forms. One common form spreads to the thyroid as part of generalized dissemination, and the other one is focal or caseous tuberculosis of the thyroid, presenting as a nodule, thyroiditis, an abscess, or a carcinoma-like mass. The differential diagnosis from malignancy and other non tuberculous granulomatous lesion is impossible upon the clinical ground. Surgical intervention is essential in order to establish the definitive diagnosis and to exclude the possibility of tumors. We experienced a case of the tuberculosis of the thyroid gland presenting with palpable thyroid nodule in a 44 year-old female patient. She was clinically and biochemically euthyroid and her CT scans demonstrated multiple low density in both thyroid gland with strands in the subcutaneous fat layer. The mass was removed surgically and confirmed to be tuberculosis.
Abscess ; Adult ; Diagnosis ; Diagnosis, Differential ; Epithelial Cells ; Female ; Humans ; Lymphocytes ; Subcutaneous Fat ; Thyroid Gland* ; Thyroid Nodule ; Tomography, X-Ray Computed ; Tuberculosis*