No abstract available.
Humans ; Inpatients*

No abstract available.
Marfan Syndrome*

No abstract available.
Athletes* ; Female ; Humans

No abstract available.
Pre-Eclampsia* ; Toxemia*

No abstract available.
Athletes* ; Dysmenorrhea* ; Female ; Humans

Spondylometaphyseal dysplasia (SMD) is an extremely rare, which affects the spine and metaphy-ses of the tubular bones on terms of enchondrogenesis. Children who had Kozlowski dwarfism, type of SMD are not recognized until they reach school age since they have normal clinical feature, weight and size in early childhood. Authors experienced a typical case of Kozlowski type of SMD in a 10 years old male who had i) generalized platyspondyly with anterior tapering of vertebrae ii) generalized metaphyseal dysplasia iii) minimal changes in the carpal and tarsal bones. This case is to be reported with review of references.
Child ; Dwarfism ; Humans ; Male ; Spine ; Tarsal Bones

No abstract available.
Porphyria, Acute Intermittent* ; Pregnancy*

Prazosin hydrochloride, a new antihypertensive agent with a unique sympatholytic mode of action, was evaluated in 35 cases with essential hypertension. The treatment was started with 3 or 4 mg of prazosin daily divided into 2 or 3 doses, and the dosage was gradually increased weekly up to 20 mg per day depending on the response of the blood pressure. Observations with this drug varied from three to ten weeks, the average being five weeks. In 21 out of 35 cases (60.0%), satisfactory reductions in systolic and diastolic blood pressures with prazosin were noted in both supine and standing positions. These were accompanied by no significant postural hypotension. In 15 out of 21 cases of satisfactory responders, the diastolic blood pressure fell to 90mmHg or less, and in five cases out of 14 poor responders prazosin was given only for three weeks. The average time lapse before effectiveness of the drug in mild, moderate and severe hypertensive cases was 3.3, 3.5 and 6.5weeks, respectively. The average daily effective dosage of prazosin in these groups was 7.1, 9.1 and 12.0mg, respectively. The cardinal unpleasant symptoms appeared in eight out of 35 cases during the medication. These included postural dizziness, weakness, headache, drowsiness and urinary frequency. However, in all cases, except one in which urinary frequency was noted, the symptoms were mild and transient disappearing spontaneously despite continued administration of prazosin. No significant changes were noted in complete blood conuts and routine urinalysis as well as in S-GOT, S-GPT, blood urea nitrogen and serum creatinine levels examined during and after medication.
Blood Pressure ; Blood Urea Nitrogen ; Creatinine ; Dizziness ; Headache ; Hypertension ; Hypotension, Orthostatic ; Prazosin* ; Sleep Stages ; Urinalysis

Prazosin hydrochloride, a new antihypertensive agent with a unique sympatholytic mode of action, was evaluated in 35 cases with essential hypertension. The treatment was started with 3 or 4 mg of prazosin daily divided into 2 or 3 doses, and the dosage was gradually increased weekly up to 20 mg per day depending on the response of the blood pressure. Observations with this drug varied from three to ten weeks, the average being five weeks. In 21 out of 35 cases (60.0%), satisfactory reductions in systolic and diastolic blood pressures with prazosin were noted in both supine and standing positions. These were accompanied by no significant postural hypotension. In 15 out of 21 cases of satisfactory responders, the diastolic blood pressure fell to 90mmHg or less, and in five cases out of 14 poor responders prazosin was given only for three weeks. The average time lapse before effectiveness of the drug in mild, moderate and severe hypertensive cases was 3.3, 3.5 and 6.5weeks, respectively. The average daily effective dosage of prazosin in these groups was 7.1, 9.1 and 12.0mg, respectively. The cardinal unpleasant symptoms appeared in eight out of 35 cases during the medication. These included postural dizziness, weakness, headache, drowsiness and urinary frequency. However, in all cases, except one in which urinary frequency was noted, the symptoms were mild and transient disappearing spontaneously despite continued administration of prazosin. No significant changes were noted in complete blood conuts and routine urinalysis as well as in S-GOT, S-GPT, blood urea nitrogen and serum creatinine levels examined during and after medication.
Blood Pressure ; Blood Urea Nitrogen ; Creatinine ; Dizziness ; Headache ; Hypertension ; Hypotension, Orthostatic ; Prazosin* ; Sleep Stages ; Urinalysis

PURPOSE: We analyzed disease free survival and the prognostic factors of liposarcoma in the extremity. MATERIALS AND METHODS: Between 1994 and 2005, of 44 patients who were diagnosed and treated for liposarcoma of the extremity, 40 patients were restrospectively analysed. 13 out of 40 patients got postoperative radiotherapy. We examined local recurrence, distant metastasis and disease free 5-year survival rate. We also analyzed clinical prognostic factors, such as age, gender, size of tumor, prior unplanned excision, histologic type, surgical excision margin and postoperative radiotherapy respectively. RESULTS: There were 3 cases of local recurrence and 4 cases of distant metastasis. The disease free 5-year survival rate was 85.0%. 26 patients presented with myxoid, 8 well differentiated, 4 round cell, 1 pleomorphic and 1 dedifferentiated histology. The disease free 5-year survival rate of mixoid, well differentiated and round cell liposarcoma were 100.0%, 84.6% and 75.0% (p=0.419). The 5-year disease free survival rate was 90.6% in negative surgical margin (n=25) and 62.5% in positive surgical margin (n=15) (p=0.003). CONCLUSION: Our study suggests that surgical excision margin is significant prognostic factor for 5-year disease free survival rate.
Disease-Free Survival ; Extremities ; Humans ; Liposarcoma ; Neoplasm Metastasis ; Recurrence ; Survival Rate