No abstract available.
Antigens, Human Platelet* ; Blood Platelets*

No abstract available.
Blood Donors* ; Communicable Diseases* ; Humans

No abstract available.

No abstract available.
Glycoproteins* ; Immunity, Cellular ; Klebsiella pneumoniae* ; Klebsiella*

The distribution of fibronectin and laminin in early chick embryos has been studied by immunohistochemical method. Fibronectin was detected not only at the basement membranes of neural tube, dorsal aortae and somites but also at the entire mesenchyme area. But laminin only appeared at the basement membranes. During the development of chick embryo, the distribution pattern of these glycoproteins was not changed but showed strong intensity of staining. The dorsal aorta of a 2-day-old chick embryo had several layer of fibronectin-producing cells, but was devoid of laminin. Laminin expression commenced faintly after Day 3. In the brain capillary wall, fibronectin was distributed but laminin was not at Day 10. In the cardiac jelly, fibronectin was detected as thin dotted strands but laminin was not expressed at Day 2. Along the endocardium, fibronectin was detected but laminin was not found. After Day 3, fibronectin was found as increased in endocardium, myocardium and cardiac jelly, whereas laminin expression commenced. Cushion mesenchymal cell migration and development of myocardial trabeculae were inhibited by antifibronectin injected in the cardiac jelly but not anti-laminin. Conclusively, this study suggests that fibronectin and laminin are glycoproteins in the extracellular matrix but there is a difference between their distributions. Cushion mesenchymal cell migration from endocardium and development of trabeculae in chick embryonic heart are inhibited by anti-fibronectin. This result suggests that fibronectin is a `stepping stone` for the embryonic migrating cells and triggers cell migration. But laminin may not serve as a matrix for cell migration.
Animals ; Aorta ; Basement Membrane ; Brain ; Capillaries ; Cell Movement ; Chick Embryo* ; Endocardium ; Extracellular Matrix ; Fibronectins* ; Glycoproteins ; Heart ; Laminin* ; Mesoderm ; Myocardium ; Neural Tube ; Somites

No abstract available.

No abstract available.
Humans

Red blood cells that agglutinate with most normal adult sera but never with own sera are termed polyagglutinable and can be separated by patterns of lectin reactivity into various types. Among these polyagglutination, activation of the T cryptantigen occurs when carbohydrate structures on glycophorins A and B lose sialic acid and express the disaccharide Gal beta-l-3 GalNac which reacts with the peanut agglutinin, a lectin from Arachis hypogaea. T activation is a temporary condition due to exposure of the membrane antigen to the action of microbial neuraminidase. In T activated red cells, the following hazards, which are theoretically possible, are spontaneous polyagglutination of red cells in vitro, in vivo and severe blood transfusion reactions. We experienced a case of T activation in 6 month old girl with bacterial meningitis caused by Streptococcus pneumoniae. The reactivity to lectins indicated the patient's red cells were T activated. We report a case of T activation in an infant with the review of literature.
Adult ; Arachis ; Blood Transfusion ; Erythrocytes ; Female ; Glycophorin ; Humans ; Infant ; Lectins ; Membranes ; Meningitis, Bacterial ; N-Acetylneuraminic Acid ; Neuraminidase ; Peanut Agglutinin ; Streptococcus pneumoniae

No abstract available.
Humans

Authors want to report that PTA was an out-standing therapeutic method in treatment of renovascular hypertension by renal artery stenosis due to Takaysu's arteritis in an 18-years-old Korean female. Abdominal aortogram and bilateral renal arteriogram showed mild smooth narrowing of the mid abdominal aorta of 4cm length from origin of renal arteries, complete occlusion of left renal artery from it's origin with a few small collateral arteries and severe stenosis of proximal right renal artery. PTA of right renal artery was performed with Gruntzign Balloon dialtation catheter, and the patient's blood pressure was down to 120/80 from 220/130,stable for 8 months follow-up examination. Takayasu's arteritis is one of the msot important cause of renovascular hypertension in Orenals. Multiple treatement modalities, such as steroid administration or variable surgical intervention, were attempted and limited response was presented. But PTA is a simple, cost-effective, repeated,and relatively complicaiton-free method in treatment of renovascular hypertension due ot Takayasu's arteritis, with an outstanding result, as authors case.
Angioplasty ; Aorta, Abdominal ; Arteries ; Arteritis ; Blood Pressure ; Catheters ; Constriction, Pathologic ; Female ; Follow-Up Studies ; Humans ; Hypertension, Renovascular ; Methods ; Renal Artery Obstruction ; Renal Artery ; Takayasu Arteritis