Thirty patient with essential hypertension were administered Manidipine, a new calcium antagonist, 10~20mg once daily to evaluate the hypotensive efficacy and safety for 8 weeks. And the followings were the result. 1) Patients were consists of 14 male, 16 female, aged 53 in average and classified as mild in 21 and moderate in 9 patients. 2) Optimum intial dose was 10mg and 10 to 20mg were the doses recommended. 3) Blood pressure dropped after 8 weeks 24/13mmHg in average, rewarding 80% effectiveness and normalized in 87%. 4) Most frequent side reaction was facial flushing in 5 patiens followed by palpitation and dizziness, all of which did not disturb the continuation of medication. 5) Most of routine laboratory parameter were normal and unchanged between before and after the trial. 6) Overall rating of usefulness was 77%. In conclusion, Manidipine 10 to 20mg once daily regimen is well tolerated and effective in the treatment of mild to moderate essential hypertension.
Blood Pressure ; Calcium ; Dizziness ; Female ; Flushing ; Humans ; Hypertension* ; Male ; Reward

PURPOSE: The purpose of this study was to determine the effects of music therapy and rhythmic exercise on health related quality of life, blood pressure and upper extremity muscle strength in the institution-dwelling elderly women. METHODS: The study was designed using a nonequivalent control group pretest-posttest design. The participants consisted of 35 elders (18 in the experimental group and 17 in the control group). The music therapy and rhythmic exercise were developed by the investigators. The experimental group took part in this program twice a week for 8 weeks. The Short Form 36 health survey questionnaire, blood pressure and grasp power scale were used as instruments. The data were analyzed using SPSS 14.0. RESULTS: Repeated measures ANOVA revealed that music therapy and rhythmic exercise had positive effects on quality of life, especially on vitality, general health and mental health. Also, there were statistically significant differences in diastolic blood pressure and upper extremity muscle strength between the pretest and posttest in the experimental group. CONCLUSION: The study suggests that this program can be applied for older women in long-term facilities to improve quality of life, blood pressure and upper extremity muscle strength.
Aged ; Aged, 80 and over ; Blood Pressure/*physiology ; *Exercise Therapy ; Female ; Health Status ; Humans ; Muscle Strength/*physiology ; *Music Therapy ; Nursing Homes ; Program Evaluation ; *Quality of Life ; Questionnaires ; Upper Extremity

No abstract available.
Eczema* ; Scrotum ; Syphilis*

A 26-year-old man with a one-year history of asthma and sinusitis presented with bilateral pleural effusions, patch basilar infiltrates on a chest x-ray and a pericardial effusion on an echocardiogram. The peripheral blood showed marked eosinophilia. An obstructive pattern was also observed during the pulmonary fuction test, which was responsive to bronchodilator inhalation. Nerve conduction studies showed right sural neuropathy. Thoracentesis yielded an acidotic exudative effusion with low glucose, low C3 and eosinophilia. An open lung biopsy revealed an eosinophilic interstitial pneumonitis associated with a necrotizing eosinophilic vasculitis, and granulomatous inflammation foci. In the literature, pleural effusions were reported in 29 percent of Churg-Strauss patients, but the number of effusions was low and their characteristics have not been well described. This report describes the characteristic findings of pleural fluid and its histologic features in a case of classical Churg-Strauss syndrome.
Adult ; Asthma ; Biopsy ; Churg-Strauss Syndrome* ; Eosinophilia ; Eosinophils ; Glucose ; Humans ; Inflammation ; Inhalation ; Lung ; Lung Diseases, Interstitial ; Neural Conduction ; Pericardial Effusion ; Pleural Effusion* ; Sinusitis ; Thorax ; Vasculitis

No abstract available.

No abstract available.
Leukemia, Promyelocytic, Acute*

Background: This study compared and analyzed various concentrations of mesoporous bioactive glass (MBG) gel, commercialacidulated phosphate fluoride gel (APF-gel), and Tooth MousseTM (TM) to evaluate the enamel remineralization effect of early dental caries. Methods: The samples prepared using sound bovine teeth were subjected to MBG gel, APF-gel, and TM to measure changes insurface hardness (Vickers hardness number, VHN) and fluorescence loss values compared to those of sound teeth (ΔF).Repeated measures analysis of variance (ANOVA), Friedman’s ANOVA, Wilcoxon signed-rank test, one-way ANOVA, and Kruskal-Wallis test were used for statistical analysis. Results: The VHN was significantly increased after the two treatments compared to the initial VHN in all other groups, with theexception of the APF gel group (p＜0.05). Compared to the initial ΔF, the APF-gel group significantly decreased ΔF after two treatments, and the remaining groups exhibited significantly increased ΔF (p＜0.05). The MBG group exhibited significantly higher ΔF values than those of the APF gel and TM groups (p＜0.05). Conclusion The MBG group exerted a significantly higher remineralization effect than that of the APF gel group and exhibited asimilar or slightly higher remineralization effect compared to that of the TM group.

Background: This study compared and analyzed various concentrations of mesoporous bioactive glass (MBG) gel, commercialacidulated phosphate fluoride gel (APF-gel), and Tooth MousseTM (TM) to evaluate the enamel remineralization effect of early dental caries. Methods: The samples prepared using sound bovine teeth were subjected to MBG gel, APF-gel, and TM to measure changes insurface hardness (Vickers hardness number, VHN) and fluorescence loss values compared to those of sound teeth (ΔF).Repeated measures analysis of variance (ANOVA), Friedman’s ANOVA, Wilcoxon signed-rank test, one-way ANOVA, and Kruskal-Wallis test were used for statistical analysis. Results: The VHN was significantly increased after the two treatments compared to the initial VHN in all other groups, with theexception of the APF gel group (p＜0.05). Compared to the initial ΔF, the APF-gel group significantly decreased ΔF after two treatments, and the remaining groups exhibited significantly increased ΔF (p＜0.05). The MBG group exhibited significantly higher ΔF values than those of the APF gel and TM groups (p＜0.05). Conclusion The MBG group exerted a significantly higher remineralization effect than that of the APF gel group and exhibited asimilar or slightly higher remineralization effect compared to that of the TM group.

Background: This study compared and analyzed various concentrations of mesoporous bioactive glass (MBG) gel, commercialacidulated phosphate fluoride gel (APF-gel), and Tooth MousseTM (TM) to evaluate the enamel remineralization effect of early dental caries. Methods: The samples prepared using sound bovine teeth were subjected to MBG gel, APF-gel, and TM to measure changes insurface hardness (Vickers hardness number, VHN) and fluorescence loss values compared to those of sound teeth (ΔF).Repeated measures analysis of variance (ANOVA), Friedman’s ANOVA, Wilcoxon signed-rank test, one-way ANOVA, and Kruskal-Wallis test were used for statistical analysis. Results: The VHN was significantly increased after the two treatments compared to the initial VHN in all other groups, with theexception of the APF gel group (p＜0.05). Compared to the initial ΔF, the APF-gel group significantly decreased ΔF after two treatments, and the remaining groups exhibited significantly increased ΔF (p＜0.05). The MBG group exhibited significantly higher ΔF values than those of the APF gel and TM groups (p＜0.05). Conclusion The MBG group exerted a significantly higher remineralization effect than that of the APF gel group and exhibited asimilar or slightly higher remineralization effect compared to that of the TM group.

No abstract available.
Amnion* ; Endometriosis* ; Endometrium* ; Female