This report describes clinical cases of a palato-gingival groove on a maxillary lateral incisor with associated localized periodontal disease and pulp necrosis. The tooth of the first case was extracted because of severe bone destruction. The palato-gingival groove of the second case was eliminated using a round bur, and the resulting defect was filled with synthetic graft and covered by an absorbable membrane. Both diagnosis and treatment of palato-gingival groove were very difficult and usually extraction of the involved tooth is the treatment of choice, but combined endodontic-periodontic treatment allowed the tooth to be saved.
Dental Pulp Necrosis ; Diagnosis ; Incisor* ; Membranes ; Periodontal Diseases ; Tooth ; Transplants

Alveolar Ridge Augmentation ; Ameloblastoma ; Dental Implants ; Humans ; Mandible ; Maxilla ; Osseointegration ; Osteogenesis, Distraction ; Osteotomy ; Tissue Expansion ; Titanium ; Transplants

Systemic infection with Aspergillus is an opportunistic disease that affects mainly immunocompromised hosts, and is associated with a high mortality rate. It typically occurs in patients with several predisposing factors, but Aspergillus endocarditis of native valves is rare and experience in diagnosis and treatment is limited. We report a case of native valve endocarditis caused by Aspergillus. A 35-yr-old male patient who underwent pericardiocentesis four months previously for pericardial effusion of unknown etiology presented with right leg pain and absence of the right femoral artery pulse. Cardiac echocardiography revealed severe mitral insufficiency with large mobile vegetations, and computed tomographic angiography showed embolic occlusion of both common iliac arteries. We performed mitral valve replacement and thromoembolectomy, and Aspergillus was identified as the vegetation. We started intravenous amphotericin B and oral itraconazole, but systemic complications developed including superior mesenteric artery aneurysm and gastrointestinal bleeding. After aggressive management, the patient was discharged 78 days post surgery on oral itraconazole. He was well at 12 months post discharge but died in a traffic accident 13 months after discharge.
Administration, Oral ; Adult ; Amphotericin B/administration & dosage ; Antifungal Agents/administration & dosage ; Aspergillosis/complications/*diagnosis/drug therapy ; Aspergillus/isolation & purification ; Endocarditis/*diagnosis/surgery/ultrasonography ; Heart Valve Diseases/*diagnosis/microbiology/surgery ; Humans ; Itraconazole/administration & dosage ; Male ; Postoperative Complications/microbiology ; Tomography, X-Ray Computed

PURPOSE: To investigate the accommodating potency of the 1CU accommodative posterior chamber intraocular lens (PC IOL), according to pilocarpine-induced ciliary muscle contraction, near visual acuity, and distance-corrected near visual acuity after implantation of the IOL. METHODS: In a prospective study, 9 eyes of 7 patients (mean age 48+/-14.9 years [range 23 to 71 years]) had phacoemulsification and PC IOL (1CU(R), Humanoptics). Distance refraction, distance visual acuity (VA), distance-corrected VA (DCVA), near visual acuity (NVA), and distance-corrected near visual acuity (DCNVA) were determined at 2 week, 1, 2, 6, and 12 months after surgery. Anterior chamber depth (ACD) was measured 3 times with the Orbscan(R) (Orbtek, U.S.A.), and averaged. Then ACD was repeatedly measured within 90 minutes after administration of pilocarpine 2% eyedrops 3 times at 10 minutes interval. RESULTS At 2 weeks, 1, 2, 6 and 12 months after surgery, the mean DCNVA was 0.55+/-0.23, 0.37+/-0.14, 0.40+/-0.22, 0.51+/-0.20, and 0.56+/-0.20, respectively. The mean ACD decrease (mm) was 0.57+/-0.77, 0.91+/-0.69, 0.17+/-0.45, 0.35+/-0.40 and 0.59+/-0.31, respectively, using Orbscan(R) after pilocarpine 2% eyedrops. There was statistically significant correlation between the pilocarpine-induced IOL movement and DCNVA (r=0.439, P=0.012). CONCLUSIONS: 1CU accommodative PC IOL provided relatively good DCNVA and accommodating potency for up to 1 year. It is necessary to investigate accommodative change for a longer time period.
Anterior Chamber* ; Humans ; Lenses, Intraocular* ; Muscle Contraction ; Ophthalmic Solutions ; Phacoemulsification ; Pilocarpine ; Prospective Studies ; Visual Acuity

PURPOSE: To investigate the accommodating potency of the 1CU accommodative posterior chamber intraocular lens (PC IOL), according to pilocarpine-induced ciliary muscle contraction, near visual acuity, and distance-corrected near visual acuity after implantation of the IOL. METHODS: In a prospective study, 9 eyes of 7 patients (mean age 48+/-14.9 years [range 23 to 71 years]) had phacoemulsification and PC IOL (1CU(R), Humanoptics). Distance refraction, distance visual acuity (VA), distance-corrected VA (DCVA), near visual acuity (NVA), and distance-corrected near visual acuity (DCNVA) were determined at 2 week, 1, 2, 6, and 12 months after surgery. Anterior chamber depth (ACD) was measured 3 times with the Orbscan(R) (Orbtek, U.S.A.), and averaged. Then ACD was repeatedly measured within 90 minutes after administration of pilocarpine 2% eyedrops 3 times at 10 minutes interval. RESULTS At 2 weeks, 1, 2, 6 and 12 months after surgery, the mean DCNVA was 0.55+/-0.23, 0.37+/-0.14, 0.40+/-0.22, 0.51+/-0.20, and 0.56+/-0.20, respectively. The mean ACD decrease (mm) was 0.57+/-0.77, 0.91+/-0.69, 0.17+/-0.45, 0.35+/-0.40 and 0.59+/-0.31, respectively, using Orbscan(R) after pilocarpine 2% eyedrops. There was statistically significant correlation between the pilocarpine-induced IOL movement and DCNVA (r=0.439, P=0.012). CONCLUSIONS: 1CU accommodative PC IOL provided relatively good DCNVA and accommodating potency for up to 1 year. It is necessary to investigate accommodative change for a longer time period.
Anterior Chamber* ; Humans ; Lenses, Intraocular* ; Muscle Contraction ; Ophthalmic Solutions ; Phacoemulsification ; Pilocarpine ; Prospective Studies ; Visual Acuity

OBJECTIVE: In the human body the embryo initially gmws in the fallopian tube which is maintained in an 3-8% O2 concentration environment, and various substances such as growth factors and antioxidants present in tbe tubal fluid assists in maintaining a healthy environment for embryo development. But in IVF programs embryo cultures are conducted in incubators with 21.9% O2 and 5% CO2 condition, and such high oxygen concentrations have been reported to increase the production of oxygen free radicals within the embryo and is detrimental to the growth and development of the embryo. The objective of this study, therefore, is to determine the culture conditions which will decrease oxygen free radical production and thereby minimize the injury to the embryo. METHODS: Six to eight week old ICR strain mice embryos were cultured in 5% or 21.9% O2 conditions and in culture media to which inaement concentrations of superoxide dismutase (SOD) had been and the H2O2 concentration within the embryo, embryo developmental rate, and degree of fragmentation of the embryos was investigated. RESULTS: The control gmup embryos which were cultured in 21.9% O2 condition without addition of SOD showed developmental arrest at the 2-cell stage or fragmentation, while those cultured in 21.9% O2 condition with addition of SOD showed development to the blastocyst stage with deaeased fragmentation. In particular, the blastulation and fragmentation rates were the lowest in the group to which 500 IU/ml of SOD was added, but in the 5% O2 enviranment group many embryos reached the blastocyst stage and with no difference in frapnentation with or without addition of SOD. The HO relative intensity (120.5+/-20.2) within the embryos cultured in 21.9% O2 environment without SOD was significantly higher than that (56.8+/-10.8) of group with SOD (p<0.05). As showing that in the 5% O2 environment group without SOD it was 43.8+/-7.8 and in the group with SOD it was 37.3+/-5.4, the H2O2 concentration within embryos cultured in 5% 02 condition was significantly lower those that of 21,9% 02 environment regardless of SOD addition (p<0.05). CONCLUSION: The optimal oxygen concentration in incubator for mice embryo cultures is that which is similar to the 5% 0 concentration in vivo. When 20% 02 incubators are routinely used, the addition of SOD to the culture media will decrease the H2O2 concentration within the embryos with subsequent improvement in development. The optimal concentration which should be used is thought to be 500 IU/ml. It is suggested that the use of the above method in human IVF-ET programs will lead to improved embryo quality and enhanced pregnancy rates.
Animals ; Antioxidants ; Blastocyst ; Culture Media ; Embryonic Development ; Embryonic Structures* ; Fallopian Tubes ; Female ; Free Radicals ; Growth and Development ; Human Body ; Humans ; Incubators ; Intercellular Signaling Peptides and Proteins ; Mice* ; Oxygen* ; Pregnancy ; Pregnancy Rate ; Superoxide Dismutase* ; Superoxides*

PURPOSE: This study was conducted to perform a comparative analysis of the efficacy and safety of conventional transurethral resection of the prostate (TUR-P), transurethral resection in saline (TURIS), and TURIS-plasma vaporization (TURIS-V) when performed by a single surgeon for benign prostatic hyperplasia (BPH). MATERIALS AND METHODS: The clinical data of 73 consecutive men who underwent conventional TUR-P (39), TURIS (19), or TURIS-V (15) for BPH were retrospectively analyzed. All procedures were carried out by a single surgeon between October 2007 and April 2010. The patients were assessed preoperatively and perioperatively and were followed at 1, 3, and 6 months postoperatively. Patient baseline characteristics, perioperative data, and postoperative outcomes were compared, and major complications were recorded. RESULTS: In all groups, significant improvements in subjective and objective voiding parameters were achieved and were sustained throughout follow-up. TURIS-V had the shortest operation time compared with conventional TUR-P and TURIS (p=0.211). TURIS-V significantly decreased procedural irrigation fluid volume, postoperative irrigation duration, catheter duration, and hospital stay compared with conventional TUR-P and TURIS. There were no significant differences between the groups in hemoglobin levels or serum sodium levels before and after the operations. There were three transfusions and four clot retentions in the TUR-P group, and one transfusion and one clot retention in the TURIS group. The TURIS-V group had no complications. CONCLUSIONS: TURIS and TURIS-V were effective for the surgical treatment of BPH in addition to conventional TUR-P. TURIS-V was not inferior to conventional TUR-P or TURIS in terms of safety.
Catheters ; Follow-Up Studies ; Hemoglobins ; Humans ; Length of Stay ; Male ; Pilot Projects ; Prostate ; Prostatectomy ; Prostatic Hyperplasia ; Retention (Psychology) ; Retrospective Studies ; Sodium ; Transurethral Resection of Prostate ; Urologic Surgical Procedures ; Volatilization

The development of colorectai cancer following pelvic irradiation has been a much less common event. A 58-years-old woman presented with tenesmus for 5 months. She had a stage IIb, carcinoma of the cervix for which she underwent radiation therapy in 27 years before. Colonscopic findings revealed polypoid mass and irregular ulceration on the rectum and proctitis associated with stricture that was compatible with her previous history of radiation. Histoyathological examination of the polypectomy specimen disclosed adenocarcinoma. So we reported a case of radiation induced carcinoma of reotum which might be the first case in Korean literature. It therefore, behooves the clinician who follows patients whose carcinoma of the cervix or corpus uteri has been cured by radiation therapy to be vigilant for the subsequent development of colon and rectal cancer.
Adenocarcinoma* ; Cervix Uteri ; Colon ; Constriction, Pathologic ; Female ; Humans ; Proctitis ; Rectal Neoplasms ; Rectum ; Ulcer ; Uterus

BACKGROUND: Secondary spontaneous pneumothorax is caused by various underlying lung diseases, and this is despite that primary spontaneous pneumothorax is caused by rupture of subpleural blebs. The treatment algorithm for secondary pneumothorax is different from that for primary pneumothorax. We studied the recurrence rate, the characteristics of recurrence and the treatment outcomes of the patients with secondary spontaneous pneumothorax. MATERIAL AND METHOD: Between March 2005 to March 2007, 85 patients were treated for their first episodes of secondary spontaneous pneumothorax. We analyzed the characteristics and factors for recurrence of secondary spontaneous pneumothorax by conducting a retrospective review of the medical records. RESULT: The most common underlying lung disease was pulmonary tuberculosis (49.4%), and the second was chronic obstructive lung disease (27.6%). The recurrence rate was 47.1% (40/85). The second and third recurrence rates were 10.9% and 3.5%, respectively. The mean follow up period was 21.1+/-6.7 months (range: 0~36 month). For the recurrence cases, 70.5% of them occurred within a year after the first episode. The success rates according to the treatment modalities were thoracostomy 47.6%, chemical pleurodesis 74.4%, bleb resection 71% and Heimlich valve application 50%. Chemical pleurodesis through the chest tube was the most effective method of treatment. The factor that was most predictive of recurrence was 'an air-leak of 7 days or more' at the first episode. (p=0.002) CONCLUSION: The patients who have a prolonged air-leak at the first episode of pneumothorax tend to have a higher incidence of recurrence. Further studies with more patients are necessary to determine the standard treatment protocol for secondary spontaneous pneumothorax.
Blister ; Chest Tubes ; Clinical Protocols ; Follow-Up Studies ; Humans ; Incidence ; Lung Diseases ; Medical Records ; Pleurodesis ; Pneumothorax ; Pulmonary Disease, Chronic Obstructive ; Recurrence ; Retrospective Studies ; Rupture ; Thoracostomy ; Tuberculosis, Pulmonary

Endomyocardial fibrosis(EMF) is an unusual type of cardiomyopathy characterized by a restriction to the ventricular filling and an obliteration of the inflow portion in the ventricular cavity by a fibrosis and often by a thrombus formation. The atrioventricular valve may be involved, resulting in an atrioventricular valvular regurgitation. The only known effective treatments are endomyocardiectomy and replacement of regurgitant AV valves. We report the experience of a case of EMF which required surgical management.
Cardiomyopathies ; Endomyocardial Fibrosis* ; Fibrosis ; Thrombosis