1.Epidermal Glycogen in the Diseases Showing Epidermal Hyperplasia.
In Seong JANG ; Jong Myung HYUN ; Soo Nam KIM
Korean Journal of Dermatology 1984;22(4):387-393
In order to assess the epidermal glycogen in the epidermal hyperplastic disease, PAS(Periodic Acid Schiff) stain with or without diastase is used. Epidermal PAS positive reaction is significantly increased in psoriasis (90. 0%), verruca vulgaris (100%) and lichen simplex chronicus (100%) than control group (12, 5%) Epidermal PAS positive reaction is relatively increased in prurigo nodularis(66. 7 %) and chronic contact dermatitis (75%) Strong PAS positive reaction is noticed in 3 of 5 cases (60%) with verruca vulgaris, but none of 22 cases with psoriasis. It is suggested that epidermal glycogen epidermal hyperplasia and that the more glycogen accumulated. than control group (12. 5%) in 3 of 5 cases (60%) with verruca vulaccumulation is accompanied with the hyperplastic the epidermis is, the more glycogen accumulated.
Amylases
;
Dermatitis, Contact
;
Epidermis
;
Glycogen*
;
Hyperplasia*
;
Neurodermatitis
;
Prurigo
;
Psoriasis
;
Warts
2.Redundant nerve roots in patients with degenerative lumbar spinal stenosis.
Won Sik CHOY ; Sung Soo JOH ; Chang Hyun BAIK ; Hyun Jin JANG
The Journal of the Korean Orthopaedic Association 1991;26(4):1226-1232
No abstract available.
Humans
;
Spinal Stenosis*
3.Evaluation of Lipoprotein(a) as a Risk Factor for Coronary Artery Disease.
Hyun Young PARK ; Han Soo KIM ; Hyuck Moon KWON ; Yang Soo JANG ; Seung Yun CHO ; Hyun Seung KIM
Korean Circulation Journal 1993;23(4):542-548
Lipoprotein(a)[Lp(a)] is a LDL-like particle with a glycoprotein called apo(a) attached to its apoB through disulfide bond. Many case-control studies support the opinion that plasma Lp(a) levels were associated with coronary artery disease. This study was conducted to assess the relationship between plasma Lp(a) level and coronary artery disease in Korean population. Serum levels of Lp(a), in addition to other lipids and known clinical risk factors for coronary artery disease were determined in 92 subjects undergoing coronary angiography. Among them 30 patients had no obstruction in the coronary artery(cath-control group), while the others revealed the presence of coronary artery stenosis more than 50%(CAD group). The Lp(a) levels of the CAD group were significantly higher the those of cath-control group(31.8+/-25.0mg/dl vs 14.6+/-11.9mg/dl, p<0.005). Other lipids except triglycerides(166.9+/-70.5mg/dl vs 116.2+/-56.1mg/dl, p<0.005) were not significantly different between two groups. The patients with significant coronary artery disease of two or more vessels were found to have higher Lp(a) levels than those of one vessel disease. Lp(a) levels had no relations with other lipids, diabetes, smoking, hypertension and age. Stepwise discriminant analysis revealed that Lp(a) was the best discriminator among risk factors for coronary artery disease. These results suggested that Lp(a) level was a significant independent risk factor for coronary artery disease.
Apolipoproteins B
;
Case-Control Studies
;
Coronary Angiography
;
Coronary Artery Disease*
;
Coronary Stenosis
;
Coronary Vessels*
;
Glycoproteins
;
Humans
;
Hypertension
;
Lipoprotein(a)*
;
Plasma
;
Risk Factors*
;
Smoke
;
Smoking
4.An Evaluation of the Accuracy of Mini-Wright Peak Flow Meter.
Young Il KOH ; In Seon CHOI ; Hyun Ju NA ; Seok Chae PARK ; An Soo JANG
Tuberculosis and Respiratory Diseases 1997;44(2):298-308
BACKGROUND: Portable devices for measuring peak expiratory flow(PEF) are now of proved value in the diagnosis and management of asthma and many lightweight PEF meters have become available. However, it is necessary to determine whether peak expiratory flow rate(PEFR) measurements measured with peak flowmeters is accurate and reproducible for clinical application. The aim of the present study is to define accuracy, agreement, and precision of mini-Wright peak flow meter(MPFM) against standard pneumotachygraph. METHODS: The lung function tests by standard pneumotachygraph and PEFR measurement by MPFM were performed in a random order for 2 hours in 22 normal and 17 asthmatic subjects and also were performed for 3 successive days in 22 normals. RESULTS: The PEFR measured with MPFM was significantly related to the PEFR and FEV1 measured with standard pneumotachygraph in normal and asthmatics(for PEFR, r=0.92 p<0.001; for FEV1, r=0.78 ; p<0.001). The accuracy of MPFM was within 10%(limits of accuracy recommeded by NAEP) in all the subjects or 22 normal, mean difference from standard pneumotachygraph being I 6.5L/min(percentage of difference being 2.90%) or 1 0.6L/min(percentage of difference being 1.75%), respectively. According to the method proposed by Bland and Altman, the 95% limits of the distribution of differences between MPFM and standard pneumotachygraph after correction of PEFR using our regression equation were +38.2 and -71.5L/min in all the subjects or -20.49~ + 9.49L/min in 22 normal and was similar to the intraindividual agreements for 3 successive days in normal. There was no statistically significant difference of PEFR measured with MPFM and standard pneumotachygraph among three days(p>0.05) and the coefficient of variation(2.4 1.2%) of PEFR measured with MPFM was significantly lower than that( 5.2 3.5%) with standard pneurnotachygraph in normal (p<0.05). CONCLUSION: This results suggest that the MPFM was as accurate and reproducible as standard pneumotachygraph for monitoring of PEFR in the asthmatic subjects.
Asthma
;
Diagnosis
;
Flowmeters
;
Peak Expiratory Flow Rate
;
Respiratory Function Tests
5.Changing indication & clinical evaluation of 1238 vaginal hysterectomies.
Keun Soo CHEON ; Eui Yeol LEE ; Jang Hyun NAM ; Keun Young LEE ; Sung Won KANG
Korean Journal of Obstetrics and Gynecology 1991;34(11):1592-1602
No abstract available.
Female
;
Hysterectomy, Vaginal*
6.Two cases of pruritic urticarial papules and plaques of pregnancy.
Jin Kook PARK ; In Hyun KIM ; Suk Ryong JANG ; Moon Jong KIM ; Bong Soo HANG
Korean Journal of Perinatology 1993;4(2):241-246
No abstract available.
Pregnancy*
7.A Case of Primary Cutaneous Mucinous Adenocarcinoma.
Jang Hyun SHIN ; Hwan Tae SUNG ; Seung Yong JUNG ; Eil Soo LEE
Korean Journal of Dermatology 1999;37(4):523-527
We report a case of primary cutaneous mucinous adenocarcinotna in a 64-year-old female. The tumor was about 2cm in size, forminga round dome-shaped alopecic scalp mass which had gradually increased in size over about 5 years, Histalogic examination revealed that the tumor was divided into numerous compartments by strands of fibrous tissue. In each compartment, abundant amounts of pale-staining mucin surrounded nests or cords of moderately anaplastic epithelial cells. We couldn't find any evidence of internal neoplasms as a source of metastasis. We resected the tumor with approximately a 1 cm margin and then performed a split thickness skin graft.
Adenocarcinoma, Mucinous*
;
Betazole
;
Epithelial Cells
;
Female
;
Humans
;
Middle Aged
;
Mucins*
;
Neoplasm Metastasis
;
Scalp
;
Skin
;
Transplants
8.A Case of Spindle Cell Hemangioendothelioma.
Jun Gyu JANG ; Hyun Chul KIM ; Young Soo CHAE ; Kee Suck SUH ; Sang Tae KIM
Korean Journal of Dermatology 1997;35(2):322-326
Spindle cell hemangioendothelioma was first described in 1986 by Weiss and Enzinger as a low grade angiosarcoma resr mbling a cavernous hemangioma and kaposis sarcoma. Recently, it is suggested to be non neoplastic lesion or reactive process arising from pre-existing vascular mal- formation. We report a case of spindle cell hemangioendothelioma in a 9-month-old boy. He had multiple, variable sized, colorful, cutaneous or subcutaneous nodules on the forearm and hand. The tumor first appeared on the forearm as erythematous patches at birth and grew rapidly with- in 3 months. Histopatholgical findings showed that the lesion was composed of thin walled cavernous spaces mixed with spindle cells and occasional epithelioid endothelial cells containing intracytoplasmic vacuole. Most af the endothelial cells lining the cavernous spaces and intracytoplasmic lumina, were positive for factor VIII associated antigen. But the spindle cells were negative. Atypical vascular structures resembling arteriovenous shunts were noted around the tumor suggesting a reactive proliferation due to disturbance of local blood flow. Several turnors were excised. No recurrence has been recognized in the one year- follow-up period.
Endothelial Cells
;
Factor VIII
;
Follow-Up Studies
;
Forearm
;
Hand
;
Hemangioendothelioma*
;
Hemangioma, Cavernous
;
Hemangiosarcoma
;
Humans
;
Infant
;
Male
;
Parturition
;
Recurrence
;
Sarcoma, Kaposi
;
Vacuoles
9.Usefulness of Dipyridamole and Dobutamine Stress Echocardiography in Myocardial Infarction.
Sang Wook LIM ; Hyuck Moon KWON ; Yang Soo JANG ; Hyun Seung KIM
Korean Circulation Journal 1994;24(1):86-98
BACKGROUND: The dipyridamole and dobutamine stress echocardiography have been studied as a non-invasive diagnostic test in coronary artery disease. Recently, some authors have extended the usefulness of these tests to predicting the prognosis of myocardial infarction patients. But as far as we know, there was no literature which tried boh tests to the same infarcted patients group. So, we performed both tests in the 23 infarcted patients to compare and evaluate both tests as predicting the prognosis in myocardial infarction. METHODS: Patients underwent (1) two-dimensional echocardiography under basal condition and after dipyridamole infusion for 4 minites at the dose of 0.14mg/kg/min, (2) another two dimensional echocardiography under basal and during dobutamine infusion at each dose of 5 to a maximum of 20microg/kg/min at 1 or 2 days after dipyridamole stress echocardiography, and (3) coronary and left ventricular angiography. Preinfusion and peak infusion images were analyzed independently by two different observers using Nova Micro Sonic soft were(DataVueII and ColorVue II analysis system). The segmental wall motions were scored as follows ; hyperkinetic : 1, normal : 2, hypokinetic : 3, akinetic : 4. THe test response was considered positive if abnormal wall motion and reduced myocardial thickening were observed during drug infusion at the vascular distributions except the akinetic infarcted segment identified during basal condition. The coronary angiography was analyzed by measuring the maximal luminal diameter stenosis with caliper and 50% or greater diameter narrowing was considered significant. The sensitivity and specificity were calculated by comparing echocardiographic prediction and angiographic findings. RESULTS: 1) Among 22 patients with sufficient image in dipyridamole stress echocardiography, 13 patients have myltivessel coronary disease without resting akinesia of non-infarcted segments. Only 5 patients showed positive findings in dipyridamole stress echocardiography(sensitivity, 38.4%). Among 9 patients who has single or minimal disease, 9 patients were negative finding(specificity, 100%). 2) Among 21 patients with sufficient image in dobutamine stress echocardiography, 12 patients have multivessel coronary disease without resting akinesia of non-infarcted segments. 7 patients showed positive finding in dobutamine stress echocardiography(sensitivity, 58.3%). Among 9 patients who has single or minimal disease, 8 patients showed negative finding(specificity, 88.8%). 3) In hemodynamic changes, dipyridamole stress echocardiography showed significant changes in heart rates and double products and dobutamine stress echocardiography showed significant changes in heart rates, systolic blood pressure and double products. 4) There was no significant side effect during both stress tests inacute and old myocardial infarction patients. CONCLUSION: 1) The dobutamine and dipyridamole stress echocardiography are safe and easy test for myocardial infarction patients. 2) The dobutamine stress echocardiography has higher sensitivity than dipyrdamole stress echocardiography for identifying multivessel coronary disease in myocardial infarction patients but the dose of both drugs were relatively small to get the adequate results. So the high dose of drugs must be tried in feature study.
Angiography
;
Blood Pressure
;
Constriction, Pathologic
;
Coronary Angiography
;
Coronary Artery Disease
;
Coronary Disease
;
Diagnostic Tests, Routine
;
Dipyridamole*
;
Dobutamine*
;
Echocardiography
;
Echocardiography, Stress*
;
Exercise Test
;
Heart Rate
;
Hemodynamics
;
Humans
;
Myocardial Infarction*
;
Phenobarbital
;
Prognosis
;
Sensitivity and Specificity
10.Effects of Self-Foot Reflexology on Stress, Fatigue and Blood Circulation in Premenopausal Middle-Aged Women.
Journal of Korean Academy of Nursing 2009;39(5):662-672
PURPOSE: This study was to examine the effects of self-foot reflexology on stress, fatigue and blood circulation in premenopausal middle-aged women. METHODS: A quasi-experimental nonequivalent control group, pretest-posttest design was used. Participants were 59 premenopausal, middle-aged women in their 40s and 60s living in G city: 30 in the experiment group and 29 in the control group. Data were collected from May to August 2008. Self-foot reflexology was performed three times a week for 6 weeks for 40 min at each session. RESULTS: The results showed that self-foot reflexology was effective in reducing perceived stress and fatigue and helped blood circulation in premenopausal middle-aged women. CONCLUSION: Self-foot reflexology may be an effective nursing intervention in reducing perceived stress and fatigue and in improving blood circulation.
Adult
;
Blood Pressure/*physiology
;
Demography
;
Fatigue/*therapy
;
Female
;
Foot
;
Humans
;
Massage/*methods
;
Middle Aged
;
Patient Education as Topic
;
*Premenopause/physiology/psychology
;
Stress, Psychological/*therapy