1.Clinical Study on Antihypertensive Effect of Minizide (Prazosin Hydrochloride and Polythiazide).
Korean Circulation Journal 1985;15(3):461-465
The antihypertensive effect of Minizide(0.5mg prazosin hydrochloride and 0.25mg polythiazide per tablet)was evaluated in 30 patients with essential hypertension with a dosage of one tablet a day for four weeks. The results were as follows : 1) Of 30 patients treated with Minizide, 21 patients(70.0%) achieved normalization of blood pressure and 5 patients(16.7%) had good response. 2) Mean drop in systolic and diastolic pressure were 29.0mmHg and 15.9mmHg respectively in supine position(P<0.005). 3) Mean drop in systolic and diastolic pressure were 28.5mmHg and 16.2mmhg respectively in sitting position(P<0.005). 4) In 14 patients(46.7%) among 30 patients treated with Minizide adverse reactions developed. The most frequent one was postural dizziness(23.3%). 5) Most adverse reactions were transient and tolerable. However, in three patients(two patients with postural dizziness and one patient with dry mouth) the medication was stopped due to adverse reactions.
Blood Pressure
;
Dizziness
;
Humans
;
Hypertension
;
Polythiazide
;
Prazosin
2.A clinical study of the normal ranges of the vestibular function tests by electronystagmographic recording.
Hyung Jong KIM ; Hyun Joon LIM ; Seung Hyun KIM
Korean Journal of Otolaryngology - Head and Neck Surgery 1992;35(2):232-241
No abstract available.
Reference Values*
;
Vestibular Function Tests*
3.The Effect of Oral Mexiletine on Ventricular Arrhythmias Evaluation by Holter Monitoring.
Korean Circulation Journal 1985;15(3):441-446
The antiarrhythmic effect of oral Mexiletine was evaluated by Holter monitoring on 10 subjects with chronic high-frequency ventricular premature complexes and ventricular tachycardia referred to our cardiology clinic of Severance Hospital from June, 1982 through September, 1983. The frequency of the ventricular premature complexes and the ventricular tachycardia was measured by 24-hour ambulatory electrocardiography on each patient before and during the administration of Mexiletine(450-600 mg/day). The results were as follows : 1) In 10 patients with ventricular tachycardia total suppression of ventricular tachycardial was demonstrated in 8 patients during the administration of oral Mexilletine. 2) The number of the ventricular premature complexes was reduced markedly in 6 out of the 10 patients. 3) Side effects occurred in 5 out of 10 patients. These include tremor, weakness, dry mouth, indigestion, anorexia, chest discomfort, and dizziness but were tolerated except in one.
Anorexia
;
Arrhythmias, Cardiac*
;
Cardiology
;
Dizziness
;
Dyspepsia
;
Electrocardiography, Ambulatory*
;
Humans
;
Mexiletine*
;
Mouth
;
Tachycardia, Ventricular
;
Thorax
;
Tremor
;
Ventricular Premature Complexes
4.Two cases of distal renal tubular acidosis associated with immune-mediated diseases.
Korean Journal of Medicine 1993;45(5):664-669
No abstract available.
Acidosis, Renal Tubular*
5.Osteogenesis Imperfecta
The Journal of the Korean Orthopaedic Association 1971;6(2):159-164
Osteogenesis imperfecta is a rare affection characterized by fragility of the bones, blue sclerae, and deafness, less freqently by hypermobility of the joints. The etiology is unknown, but it appears to be a mesenchymal defect. A case of osteogenesis imperfecta(tarda form). in a 8 ycar old girl, is presented with a review of the literatures. The chief complaints were bowing deformities of the right upper arm and both lower extremities, stunted growth, blue sclerae, dental defects, weakness of the muscles and pigeon breast. X-Ray showed multiple malunited fractures of the right humerus, both femurs, and bilaterally of tibiae and fibulae.
Arm
;
Breast
;
Columbidae
;
Congenital Abnormalities
;
Deafness
;
Female
;
Femur
;
Fibula
;
Fractures, Malunited
;
Growth Disorders
;
Humans
;
Humerus
;
Joints
;
Lower Extremity
;
Muscles
;
Osteogenesis Imperfecta
;
Osteogenesis
;
Sclera
;
Tibia
6.Hand-Schuller-Christian Disease
The Journal of the Korean Orthopaedic Association 1971;6(3):283-289
In 1953, Lichtenstein suggested to use “Histiocytosis X” as an unifying diagnostic term to represent Eosinophilic granuloma, Hand-Schiiller-Christian disease, and Letterer-Siwe disease. The author experienced a case of Hand-Schuller-Christian disease in six year old girl. She has been treated under the diagnosis of Calves disease. But later, it was confirmed as Hand-Schiiller-Christian disease by clinically and pathologically, involving multiple region of entire skeletal system, but sparing the musculocutaneous and nervous system. Clinically, anemia, malaise, high fever and hepatomegaly were present. Co60 isotope irradiation combined with antibiotics was done for 87 days twice weekly in a dose of 50 R at a time. At the time of discharge clinical symptoms were subsided. In X-Ray check, one year after treatment, bony defects were consolidated with new bone and the result was successful.
Anemia
;
Anti-Bacterial Agents
;
Diagnosis
;
Eosinophilic Granuloma
;
Female
;
Fever
;
Hepatomegaly
;
Histiocytosis, Langerhans-Cell
;
Humans
;
Nervous System
7.Myotonic Dystrophy Confirmed after Cesarean Section.
Seung Hyun KIM ; Jeongmin KIM ; Taehoon HA ; Sungwon NA
Korean Journal of Critical Care Medicine 2017;32(1):81-82
No abstract available.
Cesarean Section*
;
Female
;
Myotonic Dystrophy*
;
Pregnancy
8.Ultrastructural Changes in Rat Kidney after Lead Acetate Administration.
Hyun Chul KIM ; Seung Pil KIM ; Kwan Kyu PARK
Korean Journal of Pathology 1996;30(2):73-88
This study was carried out to investigate the ultrastructural findings of rats after administration of 0.5% lead acetate with drinking water. The Sprague-Dawley rats were divided into control and experimental groups. The control group was composed of 12 rats and was orally administered with 0.5% sodium acetate. The experimental group was composed of 36 rats and orally administered with 0.5% lead acetate. Two rats in the control group and four rats in the experimental group were sacrificed on day 2, and week 1, 2, 4, 6 and 8 after administration. The kidney was extirpated and examined by electron microscopy. The results obtained were as follows: The blood lead concentration in the experimental group began to increase from the second day after administration and it increased gradually until the 6th week and it decreased at the 8 week. The urinary excretion of delta-ALA also increased from the secondary and gradually increased up to the 8th week. On electron microscopic examination, the proximal tubular cells showed fat droplets, dilatation of the endoplasmic reticulum, mitochondrial swelling, increased numbers of secondary lysosomes and myelin figure-like residual bodies and intranuclear inclusion bodies. All these findings peaked at the eighth week after administration. Ultrastructural findings after Timm sulphide silver reaction revealed the lead granules in the proximal tubular lumen and between the microvilli of the proximal tubular cells without membrane-bounded. It can be concluded that most of the changes of micro-organelles are compatible with degenerative changes of lead exposure and passive diffusion of lead granules are involved in the proximal tubular cells.
Rats
;
Animals
9.A comparative study of conversion disorder and somatization disorder about life events, social support and coping skills.
Seung Ki KIM ; Tack Sool KWEON ; Hyun Woo KIM
Journal of Korean Neuropsychiatric Association 1991;30(5):840-848
No abstract available.
Adaptation, Psychological*
;
Conversion Disorder*
;
Somatoform Disorders*
10.A comparative study of conversion disorder and somatization disorder about life events, social support and coping skills.
Seung Ki KIM ; Tack Sool KWEON ; Hyun Woo KIM
Journal of Korean Neuropsychiatric Association 1991;30(5):840-848
No abstract available.
Adaptation, Psychological*
;
Conversion Disorder*
;
Somatoform Disorders*