No abstract available.
Wilms Tumor*

No abstract available.
DNA* ; Lymphoproliferative Disorders*

No abstract available.
DNA* ; Lymphoproliferative Disorders*

When the hypopharynx is examined in the frontal view during modified Valsalva maneuver after barium swallow anoutpouching of the lateral wall of the hypopharynx resembling a deverticulum is commonly observed. Review of theliterature however fails to disclose provious documentation of systematic prospecative observation of this phenomenon. The present study has been undertaken to detemine the incidence and degree of outpouching according tothe age and sex and to assess the clinical implication of the outpouching. The clinical materials consist of 100 consecutive cases of routine upper GI series with a particular effort directed to induce hypopharyngeal out pouching by a modified Valsalva maneuver at the Department of Radiology, St. Mary's Hospital, Catholic Medical College during 6 months period from Jan. 1982. Technically, outpouching was best demonstrated in the erectposition with a slight extension of the neck during the pharyngeal phase of barium swallowing while the subjectwas instructed to blow through the closed lips. Observation were made ofhhte incidence and intensity of theoutpouching by an arbitrary line drawning to measure the depth of outpouchings. Our study revealed thathypopharyngeal outpouchings occure bilaterally in every case studied. There was definite dominancy on the rightside(p<0.01) and the outpouching was greater in intensity in male (p<0.05) and the depth varied from a few to 15mm. And there was no statistically significant difference according to the age. Outpouchings collapsed and disappeared completely after release of Valsalva maneuver and did not appear to produce any clinical symptoms. The reason of right-side dominancy should further be investigated.
Barium ; Deglutition ; Humans ; Hypopharynx ; Incidence ; Lip ; Male ; Neck ; Spectinomycin ; Valsalva Maneuver

The aim of this study was to investigate the effect of third molar extraction on the periodontal status of the adjacent second molar. A total of 61 second molars in 31 adult periodontitis patients were examined. Among them, 27 second molars without adjacent third molars were included in the test group, and 34 second molars with third molar were included in the control group. Clinical parameters including plaque index, gingival index, and pocket depth and radiographic bone loss were measured around the second molar both in test and control group. The result showed that: (1) the mean plaque index and gingival index of control group were higher than these of the test group but the difference was not statistically significant, (2) the mean pocket depth of the control group was higher than the test group significantly at distal and buccal surface, (3) radiographic bone loss was greater in control group than test group significantly, (4) in Pearson correlation analysis between the age of extraction and radiographic bone loss in the test group, a positive relationship was shown(p<0.01). Within limitation of this study, it may be concluded that third molar extraction in periodontitis patients showed an improvement in periodontal status in contrast the patients group having third molar, therefore earlier a removal of third molar may minimize radiographic bone loss of the adjacent second molar.
Adult ; Male ; Female ; Humans

PURPOSE: Persistent pyuria is one of the common complications after transurethral prostatectomy (TURP). Postoperative pyuria has an effect on postoperative voiding symptoms. Thus, postoperative urinalysis and urine culture are reliable indicators when following up voiding symptoms. In our study, possible preoperative, intraoperative and postoperative factors influencing the development and duration of pyuria and bacteriuria after TURP were evaluated. MATERIALS AND METHODS: Between January 2004 and November 2005, 82 patients who underwent TURP due to benign prostatic hyperplasia (BPH) were evaluated. The risk factors of the duration of the postoperative pyuria were divided into preoperative, intraoperative postoperative, and evaluated the differences and correlations according to these risk factors. RESULTS: The average durations of pyuria of 26 and 23 patients under and over the age of 70 were 4.12+/-2.69 and 6.61+/-4.51 weeks, respectively (p= 0.03). The average duration of pyuria of 12 patients with no preoperative pyuria and 37 with preoperative pyuria were 4.97+/-3.12 and 6.25+/-5.55 weeks, respectively (p=0.04). Separating patients according to the resected volume of prostate, the average duration of pyuria of 16 and 33 patients with resected prostate volumes greater than and less than 7g were 3.56+/-2.16 and 6.12+/-4.20 weeks, respectively (p=0.03). The age and average duration of pyuria showed a positive correlation (p=0.031). CONCLISIONS: Significant differences were observed in the duration of pyuria according to age, preoperative pyuria and resected volume of prostate.
Bacteriuria ; Humans ; Prostate ; Prostatic Hyperplasia ; Pyuria* ; Risk Factors ; Transurethral Resection of Prostate* ; Urinalysis

PURPOSE: The expression of Nitric oxide Synthase (NOS) and aquaporin (AQP) water channels in rat bladder is recently reported. The aim of this study is to evaluate the expression of inducible NOS (iNOS), aquaporin-3 (AQP-3) in cyclophosphamide (CYP) induced rat bladder. MATERIALS AND METHODS: The 32 Sprague-Dawley rats were divided into cystitis group (n=20) and control group (n=12). In cystitis group, 100mg/kg CYP was injected every second day for 1 week whereas in control group, normal saline was injected. After extracting of the bladder and dividing dome, body and trigone of the bladder, independently H&E staining and immunohistochemical staining for iNOS and AQP-3 were performed. Expressions of iNOS and AQP-3 were analyzed with a confocal laser scanning microscope and an image analyzer. RESULTS: The expression of iNOS significantly increased in the mucosa, submucosa layer of dome in cystitis group (p<0.05). The expression of AQP-3 significantly increased in the mucosa, submucosa, vessel layer of dome in cystitis group (p<0.05). CONCLUSIONS: These results suggest that inflammatory change activates NOS and AQP-3 expression in the bladder tissue of rats. These may imply that NOS and AQP-3 have a pathophyiological role in the cyclophophamide induced interstitial cystitis. Further study on the NOS and AQP-3 in bladder is needed for clinical application.
Animals ; Aquaporins ; Cyclophosphamide ; Cystitis ; Cystitis, Interstitial ; Glycosaminoglycans ; Mucous Membrane ; Nitric Oxide ; Nitric Oxide Synthase ; Rats ; Rats, Sprague-Dawley ; Urinary Bladder

No abstract available.
Guillain-Barre Syndrome

BACKGROUND: Shoulder arthroscopic surgery is frequently associated with severe postoperative pain, which can be difficult to manage without the use of high-dose opioids. Although an interscalene brachial plexus block (ISBPB) can be used to provide anesthesia for shoulder arthroscopic surgery, its effect using low-dose mepivacaine on postoperative pain management has not been reported. We hypothesized that ISBPB using a low-dose mepivacaine can provide effective postoperative analgesia for shoulder arthroscopic surgery without the need for high-dose opioids and act as a significant motor or sensory block. METHODS: This study examined a total of 40 patients, who underwent shoulder arthroscopic surgery, and received ISBPB with 10 ml of normal saline (group NS; n = 20) or 10 ml of 1% mepivacaine with epinephrine 1:200,000 (group MC; n = 20). The block was performed preoperatively. The postoperative pain score, opioid consumption, and side effect were recorded. RESULTS: The visual analog scale scores were significantly lower in group MC than in group NS at 120 minutes after shoulder arthroscopic surgery (1.9 +/- 1.0 versus 4.0 +/- 1.4). Group MC showed significantly lower fentanyl consumption after shoulder arthroscoic surgery than group NS (27 +/- 32.6 versus 79 +/- 18.9microgram). The degree of motor and sensory block after surgery was minimal. CONCLUSIONS: ISBPB using low-dose mepivacaine reduced the level of postoperative pain and fentanyl consumption without significant side effects. ISBPB using low-dose mepivacaine is a useful analgesic technique for shoulder arthroscopic surgery.
Analgesia ; Analgesics, Opioid ; Anesthesia ; Arthroscopy ; Brachial Plexus ; Epinephrine ; Fentanyl ; Humans ; Mepivacaine ; Pain, Postoperative ; Shoulder

Backgroud: Bupivacaine blocks the sodium channels enhanced by hypokalemia. Bupivacaine also inhibits the transient outward K+ current (Ito). Insulin, in contrast, enhances Ito and induces hypokalemia. The current study was performed to confirm the efficacy of insulin for the treatment of bupivacaine- induced cardiac depression in dogs. METHODS: After dogs were anesthetized with pentobarbital, 0.5% bupivacaine was administered at a rate of 0.5 mg/kg/min until S O2 decreased to 60% or less, which was defined as the point of cardiac depression in this study. The insulin group (n = 9, 16.9 +/- 3.1 kg) received 2 ml/kg of a mixed solution of regular insulin 30 units and 5% D/W 50 ml, followed by a glucose infusion (50 ml 5% dextrose in water) over 15 min. The control group (n = 9, 15.8 +/- 3.4 kg) received 2 ml/kg of 5% D/W 50 ml, followed by a normal saline infusion over 15 min. Mean arterial pressure (MAP), heart rate (HR), pulmonary artery pressure (PAP), central venous pressure (CVP), pulmonary capillary wedge pressure (PCWP), cardiac output (CO), SO2, blood gas analysis, serum electrolytes, ECG and the local anesthetic concentraton of the blood were taken. RESULTS: Changes in hemodynamic variables and ECG of the insulin group normalized more rapidly than in the control group. There were no statistical differences in serum Na and Ca2 concentratons between the two groups. The serum K concentration of the insulin group was lower than that of the control group after 5 min of resuscitation. The changes in plasma bupivacaine concentration over time were not significantly different between groups. CONCLUSIONS: Insulin is effective in reversing bupivacaine-induced cardiac depression. This study suggests insulin can be considered an immediate treatment for cardiac depression by bupivacaine.
Animals ; Arterial Pressure ; Blood Gas Analysis ; Bupivacaine ; Cardiac Output ; Central Venous Pressure ; Depression* ; Dogs ; Electrocardiography ; Electrolytes ; Glucose ; Heart Rate ; Hemodynamics ; Hypokalemia ; Insulin* ; Pentobarbital ; Plasma ; Pulmonary Artery ; Pulmonary Wedge Pressure ; Resuscitation ; Sodium Channels