1.The effects of RU 41.740, a glycoprotein extract from klebsiella pneumoniae, on peripheral blood mononuclear cells.
Moon Kyu KIM ; Dong Soo KIM ; Hyun Ok KIM
Journal of the Korean Pediatric Society 1992;35(8):1066-1072
No abstract available.
Glycoproteins*
;
Immunity, Cellular
;
Klebsiella pneumoniae*
;
Klebsiella*
2.Correlation analysis of sodium-related knowledge, dietary behavior, attitudes towards a low-salt diet and meal attitude guidance for elementary school teachers in Jeonbuk area.
Journal of Nutrition and Health 2017;50(2):180-191
PURPOSE: The purpose of the study was to identify teacher's knowledge about sodium, dietary behaviors related to sodium, attitudes towards a low-salt diet, and meal attitude guidance as well as examine the relationship between these variables. METHODS: The participants were 351 teachers at an elementary school in the Jeonbuk area. The data were analyzed using ANOVA, Duncan test, and Pearson correlation coefficients with SPSS v. 20.0. RESULTS: The score for teachers' knowledge about sodium was 12.92 points of a possible 16, the score for dietary behavior related to sodium was 46.85 points of a possible 70, and the score for attitude towards a low-salt diet was 33.63 points of a possible 50. Their score for meal attitude guidance was 59.95 points of a possible 80. The knowledge showed significant differences by hypertension drug (p < 0.05) and stress level (p < 0.05). The dietary behavior of sodium use showed significant differences by gender (p < 0.01), work experience (p < 0.05), BMI (p < 0.01), drinking (p < 0.05), concern about health (p < 0.05), and stress level (p < 0.05). The attitude towards a low-salt diet showed significant differences by gender (p < 0.05), marital status (p < 0.05), work experience (p < 0.05), drinking (p < 0.05), concern about health (p < 0.001), and stress level (p < 0.05). Meal attitude guidance showed a significant difference by marital status (p < 0.001), age (p < 0.001), work experience (p < 0.001), drinking (p < 0.01), regularity of health checkup (p < 0.001), concern about health (p < 0.001), and stress level (p < 0.05). There was a low positive correlation between knowledge about sodium and dietary behavior related to sodium as well as between dietary behavior related to sodium and attitudes towards a low-salt diet. Attitudes towards a low-salt diet showed a positive correlation with meal attitude guidance. CONCLUSION: Therefore, it is necessary to consider educational programs on increasing knowledge and attitudes towards a low-salt diet in teachers for improvement of meal attitude guidance activities for students.
Diet, Sodium-Restricted*
;
Drinking
;
Humans
;
Hypertension
;
Jeollabuk-do*
;
Marital Status
;
Meals*
;
Sodium
;
Sodium, Dietary
3.Changes in the expression of c-myc, RB and tyrosine-phosphorylated proteins during proliferation of NIH 3T3 cells induced by hyaluronic acid.
Soon Ok MOON ; Ji Hyun LEE ; Tai Jin KIM
Experimental & Molecular Medicine 1998;30(1):29-33
We have shown that hyaluronic acid stimulates the proliferation of quiescent NIH 3T3 cells. We have shown that treatment of 1 mg/ml hyaluronic acid results in increase of tyrosine phosphorylation of two proteins, MW 124 kDa and 60 kDa as detected by anti-tyrosine antibodies by Western blot analysis. Maximum phosphorylation occurred within 2 h after addition of 1 mg/ml hyaluronic acid. Stimulation of proliferation was also accompanied by increase in c-Myc protein, which was inhibited by amlloride, an inhibitor of Na+/H+ antiporter and EGTA and increase in the steady state level of pRb, the RB gene product. These results suggest that the intracellular signal transduction pathways that mediate the stimulatory effects of hyaluronic acid on cellular proliferation are similar to those of growth factors.
3T3 Cells
;
Amiloride/pharmacology
;
Animal
;
Cell Division
;
Dose-Response Relationship, Drug
;
Egtazic Acid/pharmacology
;
Hyaluronic Acid/pharmacology*
;
Mice
;
Mitogens/pharmacology*
;
Phosphoproteins/metabolism*
;
Phosphorylation
;
Proto-Oncogene Proteins c-myc/metabolism*
;
Retinoblastoma Protein/metabolism*
;
Signal Transduction
;
Sodium-Hydrogen Antiporter/antagonists & inhibitors
;
Tyrosine
4.A Study on the Status of Seeking Intervention among the Workers with Health Problems Identified by the Workers' Periodic Health Examination.
Hee Kwan CHEONG ; Joung Soon KIM ; Ok Ryun MOON ; Hyun Sul LIM
Korean Journal of Preventive Medicine 1992;25(4):343-356
Authors studied the workers' knowledge about the health problems detected through the previous workers' periodic health examination, content of follow-up management and actions taken for their health problem detected on previous health examination. From June to September 1992, workers' periodic health examination was performed on workers employed in 10 companies located in 2 middle-sized Korean cities. A questionnaire survey was done for 150 workers who reported to have D2 result of either hypertension or liver disorder at the previous workers' periodic health examination done in 1991. The results are as follows; 1. Of 160 workers who had D2 result of either hypertension or liver disorder in previous examination one year before, only 85 workers(51.3%, 43 workers with hypertension, 38 workers with live disorder) responded that they have such disorders. The other 65 workers responded to questionnaire were all those with C results. Respondents' knowledge about their diagnoses was relatively precise (95.2% in hypertension group, 94.6% in liver disorder group) but knowledge about classification of diseases was poor. 2. The main efforts to solve the health problem was self management (26 spells, 55.3%), visiting clinic or hospital (6 spells, 12.8%), use of herb medicine (2 spells, 4.3%) and use of drug store (2 spells, 4.3%) in hypertension group. In liver disorder group, 30 spells (71.4%) relied on self management, 6 spells (14.3%) on hospital or clinic and 9 spells (21.4%) had no effort to improve the health problem. Content of self management was low salt diet, quit smoking, regular exercise and quit alcohol drinking in order. Avoidance of salt in diet was high in hypertension group and quitting alcohol drinking was high in liver disorder group. In those with self management, 80.7% of hypertension group and 83.3% of liver disorder group continued previous effort. Those, however, who utilized clinic or hospital, only 16.7% and 50.0% were still visiting hospital or clinic. 3. Fifty seven percent of hypertension group and 64.3% of liver disorder group was presently smoking, 8.5% and 11.9% reduced smoking and 21.3% and 14.3% stopped smoking. Forty nine percent of hypertension group and 28.6% of liver disorder group was presently drinking. Reduced alcohol intake was reported in 29.8% and 40.5%, 12.8% and 23.8% stopped alcohol drinking. Sixty six percent of hypertension group and 73.8% of liver disorder group did no regular exercise, but 12.8% and 11.9% of each group increased their physical exercise for last one year. Forty three percent of hypertension group and 38.1% of liver disorder group was overweight (defined by bodymass index greater or equal than 25). Reduced body weight was reported in 17.2% and 16.7% of each group. Reduced dietary salt intake was high in hypertension group (51.5%). The study results suggest that follow-up management after workers' periodic health examination is not satisfactory. In order to improve this situation, adequate information on the result of the workers' periodic health examination should be distributed to each worker group with health education and counselling.
Alcohol Drinking
;
Body Weight
;
Classification
;
Diagnosis
;
Diet
;
Drinking
;
Exercise
;
Follow-Up Studies
;
Health Behavior
;
Health Education
;
Hypertension
;
Liver
;
Liver Diseases
;
Overweight
;
Surveys and Questionnaires
;
Self Care
;
Smoke
;
Smoking
5.Development and Evaluation of the Reliability and Validity of the VSSS-82 Korean Version for Measuring Satisfaction with Community-based Mental Health Services in Psychiatric Patients.
Weon Seob YOO ; Young Jeon SHIN ; Ok Ryun MOON ; Jung Hyun NAM
Korean Journal of Preventive Medicine 2001;34(3):211-218
OBJECTIVES: To develop a Korean version of VSSS-82 for measuring the multi-dimensional satisfaction with community-based mental health services in psychiatric patients and to investigate both the reliability and validity of the Korean version. METHODS: The VSSS-82 English version was translated and back-translated with some modification. Data from 68 psychosis patients using community-based mental health services in three Community Mental Health Centers (CMHCs) was collected through a personal interview survey regarding the satisfaction and suitability of service. Variability of satisfaction and internal consistency, discriminant validity, and concurrent validity of the VSSS-82 Korean version were evaluated. RESULTS: A higher number of dissatisfied subjects and significant pairwise differences for the dimensions were found. The Crohnbach's alpha coefficient, a measure of internal consistency, ranged from 0.56 (overall satisfaction) to 0.90 (skills and behavior) and significant differences in satisfaction was found in patients by the self-rated suitability of service. CONCLUSIONS: The VSSS-82 Korean version is a reliable and valid instrument for measuring multi-dimensional satisfaction with community-based mental health service.
Community Mental Health Centers
;
Community Mental Health Services
;
Humans
;
Mental Health Services*
;
Mental Health*
;
Personal Satisfaction
;
Psychotic Disorders
;
Questionnaires
;
Reproducibility of Results*
6.Stress dissipation characteristics of four implant thread designs evaluated by 3D finite element modeling.
Ok Hyun NAM ; Won Jae YU ; Hee Moon KYUNG
The Journal of Korean Academy of Prosthodontics 2015;53(2):120-127
PURPOSE: The aim was to investigate the effect of implant thread designs on the stress dissipation of the implant. MATERIALS AND METHODS: The threads evaluated in this study included the V-shaped, buttress, reverse buttress, and square-shaped threads, which were of the same size (depth). Building four different implant/bone complexes each consisting of an implant with one of the 4 different threads on its cylindrical body (4.1 mm x 10 mm), a force of 100 N was applied onto the top of implant abutment at 30degrees with the implant axis. In order to simulate different osseointegration stages at the implant/bone interfaces, a nonlinear contact condition was used to simulate immature osseointegration and a bonding condition for mature osseointegration states. RESULTS: Stress distribution pattern around the implant differed depending on the osseointegration states. Stress levels as well as the differences in the stress between the analysis models (with different threads) were higher in the case of the immature osseointegration state. Both the stress levels and the differences between analysis models became lower at the completely osseointegrated state. Stress dissipation characteristics of the V-shape thread was in the middle of the four threads in both the immature and mature states of osseointegration. These results indicated that implant thread design may have biomechanical impact on the implant bed bone until the osseointegration process has been finished. CONCLUSION: The stress dissipation characteristics of V-shape thread was in the middle of the four threads in both the immature and mature states of osseointegration.
Axis, Cervical Vertebra
;
Finite Element Analysis
;
Osseointegration
7.A case of autoimmune hemolytic anemia due to autoanti-Ce.
Oh Hun KWON ; Hyun Ok KIM ; Sung Ran CHO ; Kil Young KIM ; Kyung A LEE ; Dong Eun YONG ; Moon Jung KIM
Korean Journal of Blood Transfusion 1996;7(2):257-261
A 12-year-old female with histiocytosis X accompanied by autoimmune hemolytic anemia. During the episode of hemolysis, the hemoglobin level fell to 5.2 g/dL. The direct antiglobulin test was weakly positive. The anti-C and anti-e were identified in her serum. The Rh subgroup of her family(father, mother and brother) including the patient, were all same as DCe. The antibodies which showed anti-C and anti-e specificity were confirmed autoanti-Ce(non-separable) using the serum absorbed with various known Rh phenotyped RBCs. Two packed RBCs phenotyped as DeE were transfused for correction of anemia. Acute and delayed hemolytic transfusion reactions were not noted after transfusion. Identification of blood group specific autoantibodies may be benificial in such case for blood transfusion.
Anemia
;
Anemia, Hemolytic, Autoimmune*
;
Antibodies
;
Autoantibodies
;
Blood Group Incompatibility
;
Blood Transfusion
;
Child
;
Coombs Test
;
Female
;
Hemolysis
;
Histiocytosis, Langerhans-Cell
;
Humans
;
Mothers
;
Sensitivity and Specificity
8.Management for Obstructed Carcinoma of the Left Colon.
Hyun Chul KIM ; Moo Jun BAEK ; Nae Kyung PARK ; Moon Soo LEE ; Yong Suk JANG ; Ok Pyung SONG
Journal of the Korean Society of Coloproctology 1998;14(2):209-216
The management of malignant left colon obstruction remains a difficult problem. Conventional surgical treatment is muti-staged and each stage carries its own morbidity and mortality. The purpose of this study is to identify the feasibility and safety of one stage operation in patients presenting with acute obstruction of the left colon. From January 1991 to June 1996, 29 patients received one stage resection for acutely obstructed carcinoma of the left colon at Soonchunhyang University Chunan Hospital. Subtotal colectomies were performed in 9 patients(31.0%), left hemicolectomies in 6(20.7%), low anterior resection in 6(20.7%), sigmoid colectomy in 4(13.8%), anterior resection in 4 patients(13.8%). Subtotal colectomy was performed in patients with massively distended colon of dubious viability and to contain ischemic lesions at proximal colon. Total operative mortality was 6.9%: 5% in the immediate resection with anastomosis group, 11.1% in subtotal colectomy group. Complications included wound infection(4), fecal incontinence(2), intestinal obstruction(2), anastomotic leakage(1), upper G-I bleeding(1), postoperative bleeding(1), pulmonary complication(1). Our results suggest that resection and primary anastomosis can be performed with acceptable morbidity and mortality in patients with acute malignant obstruction of the left colon.
Chungcheongnam-do
;
Colectomy
;
Colon*
;
Colon, Sigmoid
;
Humans
;
Mortality
;
Wounds and Injuries
9.The Effect of the Experience of Diabetes Education on Knowledge, Self-Care Behavior and Glycosylated Hemoglobin in Type 2 Diabetic Patients.
Seung Hei MOON ; Young Whee LEE ; Ok Kyung HAM ; Soo Hyun KIM
Journal of Korean Academic Society of Nursing Education 2014;20(1):81-92
PURPOSE: This study was to identify the effect of the experience of diabetes education on knowledge, self-care behavior and glycosylated hemoglobin (HbA1C). Further, this study was held to examine about patient's preferred methods of education and re-education frequency. METHODS: 166 type 2 diabetes patients from two hospitals in Incheon participated in this study. Data were analyzed by using descriptive analysis, t-test, ANOVA, Scheffe's test and multiple regression analysis. RESULTS: 72.3% patients needed re-education and the average interval of re-education was 8.53 months. Patients preferred education methods were lectures, practical training, and studying from pamphlet. Depending on the frequency of diabetes education, there were significant differences in the level of diabetes knowledge (F=10.88, p<.001) and self-care behaviors (F=4.59, p=.012), but there was not significant difference with HbA1C (F=1.53, p=.220). As to how much the diabetes education helped managing diabetes, there was a significant difference in the level of self-care behaviors (t=2.01, p=.049), but there were not significant differences in level of knowledge (t=1.10, p=.275) and HbA1C (t=-.33, p=.746). The experience of diabetes education was a significant factor which influenced patient's knowledge (t=3.93, p<.001) and self-care behaviors (t=2.21, p<.001). But HbA1C was not influenced by the experience of diabetes education (t=-1.68, p=.096). CONCLUSION: It is necessary to provide diabetes education with appropriate interval and methods and subjects that reflect the needs of patient through the study results.
Education*
;
Hemoglobin A, Glycosylated*
;
Humans
;
Incheon
;
Lectures
;
Pamphlets
;
Self Care*
10.A Study on Factors Affecting the Suicidal Ideation in Older Adults with Osteoarthritis.
Sun Hyun LEE ; Kyong Ok OH ; Moon Hee KANG
Journal of Korean Academy of Psychiatric and Mental Health Nursing 2011;20(1):103-110
PURPOSE: The purpose of this study was to identify the factors influencing suicidal ideation in older adults with osteoarthritis. METHODS: Data was collected by questionnaires using face-to-face interviews from 87 outpatients selected at a private hospital. The data was analyzed using SPSS/WIN 12.0. RESULTS: The mean scores of disability, depression and suicidal ideation were 58.5, 18.1 and 8.3 respectively. There were significant differences in suicidal ideation according to socio-demographic factors such as education, present job, marital status, residence with, economic status, difference in caregiver. Depression was a significant predictor of suicidal ideation (F=51.15, p<.001). CONCLUSION: Based on the findings of this study, to prevent suicidal ideation for older adults with osteoarthritis, nursing intervention program should include psychological care for depression as well as physical care for disability reduction.
Adult*
;
Caregivers
;
Depression
;
Education
;
Hospitals, Private
;
Humans
;
Marital Status
;
Nursing
;
Osteoarthritis*
;
Outpatients
;
Questionnaires
;
Suicidal Ideation*