No abstract available.
Hemoperitoneum*

No abstract available.
Lymphoma*

No abstract available.
Breast Diseases* ; Breast* ; Estrogens* ; Progesterone* ; Receptors, Estrogen* ; Receptors, Progesterone*

No abstract available.
Bile Ducts* ; Bile*

No abstract available.
Breast Neoplasms* ; Breast*

The need for a relaparotomy shortly after an initial abdominal operation indicates a serious complication and may frequently constitute a surgical failure. Many of the postoperative symptoms that might indicate the onset of complications may be masked by the usual postoperative course. Reported findings vary widely. Thus there is no clear picture for a surgeon to use as a guide. In an attempt to obtain more definite guidelines regarding the indications for and the timing of reintervention a retrospective study based on a 7-year survey was undertaken to assess the problem of reoperation after abdominal surgery. This study consisted of a retrospective clinical analysis made an 95 patients who required reoperation due to postoperative complications and planned stage operations during 7 years from January 1990 to December 1996. The number of reoperations was 95 cases (24%) among 3932 patients who had undergone abdominal operations at our department. The sex distribution for the reoperations was 58 males and 37 cases in females. The peak age incidence was the 6th decade in 25 cases(26.3%). The most common physical findings of the patient who required reoperations were abdominal pain and tenderness (56.8%). The main cause necessitating reoperation was intestinal obstruction (25.3%). The most common types of reoperations were common bile duct exploration with T-tube insertion(24.2%). The time interval between initial operation and reoperation was within 10 days in 10 cases (10.5%) and 25 months grouped in separate admission in 36 cases (37.9%). The most frequent complication was wound infection(15.8%) and the mortality rate was 4 cases (4.2%). Conservative treatment cannot be recommended for severe complications, such as postoperative bleeding or peritonitis, due to free anastomotic leakage. However, in doubtful cases, when there is mild peritonitis of an undetermined origin, ileus, well-controlled billiary or duodenal leaks, and the like, the high mortality associated with reintervention should be borne in mind. In these cases, conservative treatment with close supervision of the patient may prove the most prudent course.
Abdomen ; Abdominal Pain ; Anastomotic Leak ; Common Bile Duct ; Female ; Hemorrhage ; Humans ; Ileus ; Incidence ; Intestinal Obstruction ; Male ; Masks ; Mortality ; Organization and Administration ; Peritonitis ; Postoperative Complications ; Reoperation* ; Retrospective Studies ; Sex Distribution ; Wounds and Injuries

The optimal treatment of primary or metastatic liver cancer is the complete surgical excision of the tumors. Hepatoma has a poor prognosis, especially in the case of unresectable hepatoma. In such cases, variable therapeutic modalities have been tried in attempts to improve the prognosis of the hepatoma patients. One of these modalities is hepatic cryosurgery, which has received increased attention recently. We have experienced four cases of hepatic cryosurgery on unresectable hepatomas at the ChungAng University Hospital in Korea, the first such cases, from September 1995 to December 1995. There was an excellent therapeutic outcome in one case. We expect that hepatic cryosurgery will serve as a new and effective therapeutic modality for unresectable hepatoma.
Carcinoma, Hepatocellular ; Cryosurgery* ; Humans ; Korea ; Liver Neoplasms ; Prognosis

No abstract available.

No abstract available.
Korea*

PURPOSE: Chromosomal instability of chromosome 18 and inhibition of the transforming growth factor beta (TGF-beta) signaling pathway, which is mediated through Smad4, play important roles in the tumorigenesis of colon cancer. This study evaluated the value of the expression of chromosome 18 monosomy in colon cancer as a prognostic factor and its correlations with the expressions of Smad4 and TGF-beta receptor II proteins. METHODS: We analyzed the rate of the expression of chromosome 18 monosomy in 66 colon cancers with using chromogenic in situ hybridization (CISH) and we evaluated its value as a prognostic factor by determining its correlation with the pathologic factors and immunohistochemical expressions of Smad4 and TGF-beta receptor II proteins. RESULTS: Of the 66 colon cancers, monosomy of chromosome 18, as determined by CISH, was observed in 18 cases (27.3%), and the decreased expression of Smad4 and TGF-beta receptor II proteins was observed in 30 cases (45.5%) and 25 cases (37.9%), respectively. The monosomy of chromosome 18 and the decreased expression of Smad4 proteins showed statistically significant correlations with the histologic differentiation, the presence of tumor emboli, the nodal status and the stage. The decreased expression of TGF-beta receptor II proteins had statistically significant correlations with the histologic differentiation, the T-stage, the nodal status and the stage. The monosomy of chromosome 18 showed a statistically significant correlation with the decreased expression of Smad4 and TGF-beta receptor II proteins. CONCLUSION: These results suggested that chromosome 18 monosomy may have prognostic value for colon cancer.
Carcinogenesis ; Chromosomal Instability ; Chromosomes, Human, Pair 18* ; Colon* ; Colonic Neoplasms* ; In Situ Hybridization ; Monosomy* ; Receptors, Transforming Growth Factor beta* ; Smad4 Protein ; Transforming Growth Factor beta*