1.A case of percutaneous transluminal angioplasty in Takayasu arteritis.
Hyun Cheol LEE ; Moon Sang PARK ; Won Kyu CHOI ; Mee Kyung NAMGOONG ; Hae Yong LEE ; Beak Keun LIM ; Hyung Goo CHO
Journal of the Korean Pediatric Society 1993;36(2):280-286
Takayasu arteritis is a chronic inflammatory arteriopathy of unknown etiology affecting large vessels, the aorta and its main branches. We experienced a case of Takayasu arteritis type III in a 9 years old girl. The diagnosis was made by physical examinations and digital subtration aortography (DSA) which showed occlusion of left subclavian artery and left renal artery and stenosis of abdominal aorta. Medical treatment and percutaneous transluminal angioplasty (PTA) were performed. A brief review of literatures was made.
Angioplasty*
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Aorta
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Aorta, Abdominal
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Aortography
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Child
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Constriction, Pathologic
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Diagnosis
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Female
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Humans
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Physical Examination
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Renal Artery
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Subclavian Artery
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Takayasu Arteritis*
2.Smoking Status and the Related Factors in the Rural Elderly.
Dal Hyun BEAK ; Byung Deog HWANG ; Hyo Jung MOON ; Hee Jung YOON ; Young Doo BACK ; Sung Kook LEE
Journal of Agricultural Medicine & Community Health 2008;33(2):243-254
OBJECTIVE: The purpose of this study was to examine smoking status and the relates factors in the rural elderly. METHODS: This study was conducted with 2,421 elderly people(male 1,273 and female 1,148) residing in the selected 25 villages, and face-to-face interviews with the subjects were made from January 1 through March 30, 2002. RESULTS: The average age of the male subjects was 72.7 and that of the female subjects 72.8. The investigation of smoking states showed that for male subjects, smokers accounted for 49.4%, nonsmokers 26.9%, and abstainers from smoking 23.7% and that for female subjects, smokers accounted for 18.3%, nonsmokers 75.4%, and abstainers from smoking 6.3%. The level of 'low ADL' was significantly higher in abstainers. In men, smoking rate had higher in alone, non-job, queerstreet, 'high ADL'. In women, smoking rate had higher in younger age, queerstreet, unhealthy, 'high ADL'. CONCLUSIONS: The smoking rate of the elderly was relatively high, especially at abstainers. The smoking status of elderly was correlated with age, family type, job, economic status by self-assessment, Self-recognition of health status, ADL level.
Activities of Daily Living
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Aged
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Female
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Humans
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Male
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Self-Assessment
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Smoke
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Smoking
3.Alternation of Cytokine mRNA Expression in Human Blood Samples before and after Allogeneic Transfusions.
Hyun Moon BEAK ; Chung Hyun NAHM ; Seung Kuk YOO ; Jong Weon CHOI ; Soo Hwan PAI ; Ji Won MO ; Chang Shin PARK
The Korean Journal of Laboratory Medicine 2003;23(4):287-291
BACKGROUND: Despite proposing clonal depletion, anergy, and alternation of cytokines in peripheral tolerance, the precise mechanism for the immunosuppressive effect of blood transfusion remains unknown. Here, we evaluated the effect of transfusion on the immune system indirectly via quantitation of leukocyte cytokine mRNA expression before and after allogeneic transfusion. METHODS: Samples were obtained from eight patients, being ordered one to four units of leukocytefree erythrocytes, before, 1, and 7 days after transfusion, from November to December, 2002 at Inha University Hospital. We explored the changes in mRNA expression of interleukin-2 (IL-2), IL-4, IL-10, tumor necrosis factor alpha (TNF-alpha) and interferon gamma (IFN-gamma). RESULTS: In four patients who received blood transfusions among eight, significant changes were observed in the blood mRNA levels of INF-gamma and IL-10. The amounts of IFN-gamma mRNA were significantly decreased a day after transfusion to 78.5% and then recovered to 110.9% 7 days later (P=0.032), whereas, that of IL-10 was increased to 151.5% a day after and recovered to 119.1% 7 days later (P=0.034). mRNA expressions of IL-2, IL-4, and TNF-alpha were not detected in all patients. CONCLUSIONS: We observed a significant decrease in leukocyte IFN-gamma mRNA expression and an increase in IL-10 mRNA after transfusion. These findings indirectly represent that down-regulation of the Th1 cells and the up-regulation of the Th2 cells could be caused by allogeneic transfusion.
Blood Transfusion
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Cytokines
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Down-Regulation
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Erythrocytes
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Humans
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Immune System
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Interferons
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Interleukin-10
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Interleukin-2
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Interleukin-4
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Leukocytes
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Peripheral Tolerance
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RNA, Messenger*
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Th1 Cells
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Th2 Cells
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Tumor Necrosis Factor-alpha
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Up-Regulation