1.The Analgesic Effect of Intraarticular Bupivacaine and Morphine after Arthroscopic Knee Surgery.
Journal of the Korean Knee Society 1998;10(1):114-118
Many authors have studies to relieve the pain after arthniscopic knee surgery. We undertook a randomized, double-blind trial to compare the efficacy of intraarticular morphme and bupivacaine between arthroscopic meniscus surgery group and cruciate ligament reconstruction group. As an results, intraarticular injection of morphine-bupivacaine combination is effective to control pain after minor athroscopic surgery such as menisectomy and meniscal repair ancf intraarticu]ar injection of mor- phine-bupivacaine combination is not effective to relieve pain after major arthroscopic surgery including cru- ciate ligament reconstruction. So, more potent analgesics should be adminishated.
Analgesia
;
Analgesics
;
Arthroscopy
;
Bupivacaine*
;
Injections, Intra-Articular
;
Knee*
;
Ligaments
;
Morphine*
2.Arthroscopic Meniscectomy in Bucket Handle Tear of the Meniscus
Dong Min SHIN ; Sang Ho HA ; Yong Hyun JEON
The Journal of the Korean Orthopaedic Association 1996;31(4):754-760
Recently, the frequency of meniscal injury of knee has been increasing due to increase of sports activities. It has been known that bucket handle tear is the most common type of the entire injuries of the meniscus. We found 127 cases of meniscal tears and experienced 42 cases of bucket handle tears in the arthroscopic findings from Jan. 1991 to April 1994 in our hospital. We analysed 31 cases which were followed up for at least 1 year. The purpose of this study is to analyse the locking history and frequency, to discuss the several types of bucket handle tear in arthroscopic view, to introduce three portal techniques using posteormedial or posterolateral portal to resect the meniscus, and to analyse our clinical results. So we concluded as follows. 1. Among the 31 cases, 23 cases(74%) had an episode of locking. 2. We found many different types of bucket handle tears in arthroscopic view and the most common type was complete tear in a classic type(11 cases). 3. We were able to resect the meniscal fragment very easily using posteromedial or posterolateral portal. 4. We obtained satisfactory results in 24 cases(77%).
Knee
;
Sports
;
Tears
3.Neuropsychological Assessment for Verbal Function.
Min Sup SHIN ; Hyun Joo LEE ; Jun Soo KWON
Journal of the Korean Society of Biological Psychiatry 1997;4(1):12-18
In this article neuroanatomical and verbal developmental process were introduced, followed that disorders and assessment of language function were reviewed. Finally, the causes and assessment of developmental dyslexia as a childhood disorder related to verbal function were reviewed.
Dyslexia
;
Neuropsychology
4.Arthroscope - Assisted Modified Weaver and Dunn Operation for Acromioclavicular Dislocation.
Byoung Hyun MIN ; Woo Sig KIM ; Shin Young KANG
The Journal of the Korean Orthopaedic Association 1998;33(4):1104-1110
There is still discussion concerning the methods for treating Tossy type 3 dislocations of the acromioclavicular joint. Since 1995, the authors have treated 10 patients of type 3 dislocations by arthroscope-assisted modified Weaver and Dunn operation with favorable results. The operation consisted of diagnostic shoulder arthroscopy, arthroscopic resection of acromial end of coracoacromial ligament with bone block, excision of distal end of clavicle, bone block transfer of coracoacromial ligament into the medullary canal of clavicle, and augmentation between coracoid process and resected distal end of clavicle with the Mersilene tape. The advantages of this arthroscope-assisted modified Weaver and Dunn operation are as follows: (1) Using the shoulder arthroscope, associated patholgy in the shoulder joint can be found and treated appropriately. (2) Arthroscopic resection of the acromial end of coracoacromial ligament can give the small incision and least damage to the deltoid muscle so that immediate post-operative range of motion exercise can be possible. (3) Bone block transfer of coracoacromial ligament and augmentation between coracoid process and resected clavicular end can prevent displacement of the resected clavicular end.
Acromioclavicular Joint
;
Arthroscopes*
;
Arthroscopy
;
Clavicle
;
Deltoid Muscle
;
Dislocations*
;
Humans
;
Ligaments
;
Range of Motion, Articular
;
Shoulder
;
Shoulder Joint
5.Treatment of Distal Femoral Fractures with a Retrograde Supracondylar Intramedullary Nail assisted with Arthroscopy.
Byoung Hyun MIN ; Shin Kang CHO ; Won Ik LEE ; Chung Su YU ; Shin Young KANG
The Journal of the Korean Orthopaedic Association 1998;33(7):1838-1845
Since Green et al has introduced a new technique of retrograde intramedullary nail, the use of retrograde interlocking intramedullary nails has been recommended as one of the treatment options for the distal femoral fracture. However there are some disadvantages that an arthrotomy is required for insertion and the knee joint could often be violated. Authors present a simple, arthroscopically assisted method using the retrograde intramedullary nailing for distal femoral fractures with minimal invasiveness to the knee. From March 1995 to March 1997, the retrograde intramedullary nail was used to treat 9 distal femoral fractures. Five of 9 patients were fractured at the distal shaft of the femur and others were fractured at the supracondylar region of the femur. Only one of the fractures was open injury(Gustilo-Anderson grade II). Significant concomitant knee joint injuries were revealed through the arthroscopy in 3 patients. Eight of 9 fractures healed by 5 months, but one fracture was not healed and required bone grafting. Average knee range of motion was 130. Complications included 1 nonunion and 1 hardware failure. There were no patellofemoral problems and no posttraumatic arthritis of the knee joint. This arthroscope-assisted method have some potential benefits that include decreased risk of damage to the knee joint, early evaluation and treatment of the associated knee joint injuries, and accurate placement of the nail.
Arthritis
;
Arthroscopy*
;
Bone Transplantation
;
Femoral Fractures*
;
Femur
;
Fracture Fixation, Intramedullary
;
Humans
;
Knee
;
Knee Joint
;
Range of Motion, Articular
6.The palato-gingival groove - anatomical anomaly occurred in maxillary lateral incisors: case reports.
Hyun Il KIM ; Young Shin NOH ; Hoon Sang CHANG ; Hyun Wook RYU ; Kyung San MIN
Journal of Korean Academy of Conservative Dentistry 2007;32(6):483-490
This report describes clinical cases of a palato-gingival groove on a maxillary lateral incisor with associated localized periodontal disease and pulp necrosis. The tooth of the first case was extracted because of severe bone destruction. The palato-gingival groove of the second case was eliminated using a round bur, and the resulting defect was filled with synthetic graft and covered by an absorbable membrane. Both diagnosis and treatment of palato-gingival groove were very difficult and usually extraction of the involved tooth is the treatment of choice, but combined endodontic-periodontic treatment allowed the tooth to be saved.
Dental Pulp Necrosis
;
Diagnosis
;
Incisor*
;
Membranes
;
Periodontal Diseases
;
Tooth
;
Transplants
7.Novel functional roles of caspase-related genes in the regulation of apoptosis and autophagy.
The Korean Journal of Physiology and Pharmacology 2016;20(6):573-580
Caspases, a family of cysteine proteases, cleave substrates and play significant roles in apoptosis, autophagy, and development. Recently, our group identified 72 genes that interact with Death Caspase-1 (DCP-1) proteins in Drosophila by genetic screening of 15,000 EP lines. However, the cellular functions and molecular mechanisms of the screened genes, such as their involvement in apoptosis and autophagy, are poorly understood in mammalian cells. In order to study the functional characterizations of the genes in human cells, we investigated 16 full-length human genes in mammalian expression vectors and tested their effects on apoptosis and autophagy in human cell lines. Our studies revealed that ALFY, BIRC4, and TAK1 induced autophagy, while SEC61A2, N-PAC, BIRC4, WIPI1, and FALZ increased apoptotic cell death. BIRC4 was involved in both autophagy and apoptosis. Western blot analysis and luciferase reporter activity indicated that ALFY, BIRC4, PDGFA, and TAK1 act in a p53-dependent manner, whereas CPSF1, SEC61A2, N-PAC, and WIPI1 appear to be p53-independent. Overexpression of BIRC4 and TAK1 caused upregulation of p53 and accumulation of its target proteins as well as an increase in p53 mRNA levels, suggesting that these genes are involved in p53 transcription and expression of its target genes followed by p53 protein accumulation. In conclusion, apoptosis and/or autophagy mediated by BIRC4 and TAK1 may be regulated by p53 and caspase activity. These novel findings may provide valuable information that will aid in a better understanding of the roles of caspase-related genes in human cell lines and be useful for the process of drug discovery.
Apoptosis*
;
Autophagy*
;
Blotting, Western
;
Caspases
;
Cell Death
;
Cell Line
;
Cysteine Proteases
;
Drosophila
;
Drug Discovery
;
Genetic Testing
;
Humans
;
Luciferases
;
RNA, Messenger
;
Up-Regulation
8.Two Cases of Angiokeratoma Circumscriptum.
Duck Hyun KIM ; Yoon Kee PARK ; Chung Koo CHO ; Min Geol LEE ; Shin Won HAN ; Keuk Shun SHIN
Korean Journal of Dermatology 1984;22(3):338-341
We report two cases of angiokeratoma circumcriptum. One of them was 20 year- old male, who had multiple dark erythematous 0.5 cm to 2 cm sized keratotic papules and nodules surrounding irregular shaped erythema scattered or grouped on the right lower leg. The other case was 36 year-old male, who had Q. 7 cm sized dark erythematous papules and 2 cm sized dark brown colored nodule with central ulceration on the medial part of the left upper thigh, The two patients had skin lesions at birth. Histopathologic finding disclosed markedly dilated vessels containing many red blood cells mainly in the papillary dermis, which in some, were surrounded by elongated rete ridge. Cavernous hemangioma like lesion was present in the lower dermis and subcutaneous fat in case 2.
Adult
;
Angiokeratoma*
;
Dermis
;
Erythema
;
Erythrocytes
;
Hemangioma, Cavernous
;
Humans
;
Leg
;
Male
;
Parturition
;
Skin
;
Subcutaneous Fat
;
Thigh
;
Ulcer
9.A Case of Primary Cutaneous Anaplastic Large Cell Lymphoma Showing Spontaneous Regression with Scar.
So Hyun PARK ; Young Min SHIN ; Woo Jin KIM ; Dong Hoon SHIN ; Jong Soo CHOI ; Ki Hong KIM
Korean Journal of Dermatology 2005;43(12):1642-1645
No abstract available.
10.Three Cases of Dermatofibrosarcoma Protuberans.
Hyun Min SHIN ; Si Yong KIM ; Sang Chin LEE ; Ki Taek HAN ; Chung Won KIM
Korean Journal of Dermatology 1997;35(2):327-332
Dermatofibrosarcoma protuberans (DFSP) is a rare, distinctive cutaneous tumor, which consists of spindle shaped ceils arranged in densely packed interlacing bundles with the storiform or cartwheel pattern. Histologically, it resembles deep growing dermatofibroma, nodular fasciitis, neurofibroma and neural sheath tumors. DFSP is one of t.he connective tissue tumors which is difficult. to diagnose histologically as well as clinically. Recently, the immunochemical staining with a monoclonal antibody to CD34 is reported to give assistance in the clear differential diagnosis of DFSP from other fibrous or neural tumors. Herein, three cases of DFSP were stained by immunohistochemical staining with S-100 protein, vimentin, factor VIII and anti-CD34 antibody in order to assess the use of anti-CD34 in the differential diagnosis of DFSP.
Connective Tissue
;
Dermatofibrosarcoma*
;
Diagnosis, Differential
;
Factor VIII
;
Fasciitis
;
Histiocytoma, Benign Fibrous
;
Neurofibroma
;
S100 Proteins
;
Vimentin