1.Requirement of B7 Molecule in Activation of Dendritic Epidermal T Cell by Transformed Keratinocyte.
Joo Hyun SHIM ; Seung Jun SEO ; Chang Kwun HONG
Korean Journal of Immunology 2000;22(4):217-223
No abstract available.
Keratinocytes*
2.Minimal Medial-row Tie with Suture-bridge Technique for Medium to Large Rotator Cuff Tears.
Hyun Il LEE ; Ho Young RYU ; Sang Jun SHIM ; Jae Chul YOO
Clinics in Shoulder and Elbow 2015;18(4):197-205
BACKGROUND: The purpose of this study was to evaluate the postoperative magnetic resonance imaging (MRI) results of minimal-tying (one medial-row tie among 4 medial-row sutures) on the medial-row in double-row suture-bridge configuration (2x2 anchor with 4x4 suture stands). METHODS: From 2011 March to 2012 July, 79 patients underwent arthroscopic rotator cuff repair using 2x2 anchor double-row configuration. The mean age was 61.3 years (range, 31-81 years). Two double-loaded suture anchors were used for medial-row. Four medialrow stitches were made with only one medial-row knot-tying (the most anterior suture). Lateral-row was secured using the conventional suture-bridge anchor technique; all 4 strands were used for each anchor. Repair integrity was evaluated with MRI at mean 6.2 months postoperatively. Retear and the pattern of retear, change of fatty infiltration, and muscle atrophy of supraspinatus were evaluated using pre- and postoperative MRI. RESULTS: Repaired tendon integrity was 38 for type I, 30 for type II, 6 for type III, 4 for type IV, and 1 for type V, according to Sugaya classification. Considering type IV/V as retear, the rate was 6.3% (5 out of 79 patients). Medial cuff failure was observed in 4 patients. Fatty atrophy of supraspinatus was significantly improved postoperatively according to Goutallier grading (p=0.01). The level of muscle atrophy of supraspinatus was not changed significantly after surgery. CONCLUSIONS: Minimal tying technique with suture configuration of four-by-four strand double-row suture-bridge yielded a lower retear rate (6.3%) in medium to large rotator cuff tears.
Arthroscopy
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Atrophy
;
Classification
;
Humans
;
Magnetic Resonance Imaging
;
Muscular Atrophy
;
Rotator Cuff*
;
Shoulder
;
Suture Anchors
;
Sutures
;
Tears*
;
Tendons
3.A Case of Zoster Duplex Bilateralis.
Bong Ju SHIN ; Joo Hyun SHIM ; Seong Jun SEO ; Chang Kwun HONG
Annals of Dermatology 2002;14(1):59-62
Herpes zoster involving noncontiguous dual dermatomes is very rare in both immunocompetent and immunocompromised persons. This unique presentation has been referred to as zoster duplex unilateralis or bilateralis, depending whether one or both halves of the body are involved. A 22-year-old woman, who had been treated for acute leukemia, congestive heart failure and chronic disseminated candidiasis, was referred to our department for painful papulovesicular eruptions on the right side of the anterior chest and upper back for 2 days, and the left buttock for 1 day. Tzanck smear revealed multinucleated giant cells with intranuclear inclusion bodies. We report a rare case of zoster duplex bilateralis.
Buttocks
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Candidiasis
;
Female
;
Giant Cells
;
Heart Failure
;
Herpes Zoster*
;
Humans
;
Intranuclear Inclusion Bodies
;
Leukemia
;
Thorax
;
Young Adult
4.A Case of Desmoplastic Malignant Melanoma.
Joo Hyun SHIM ; Seong Jun SEO ; Kye Yong SONG ; Chang Kwun HONG
Annals of Dermatology 2001;13(4):250-253
Desmoplastic malignant melanoma (DMM) is an uncommon variant of malignant melanoma featuring a proliferation of spindle cells with pronounced desmopaasia. DMM commonly occurs on the sun-damaged skin such as head and neck in older persons, and it can be associated with lentigo maligna. We report an unusual case of desmoplastic malignant melanoma that developed de novo on the trunk in a young patient.
Head
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Humans
;
Hutchinson's Melanotic Freckle
;
Melanoma*
;
Neck
;
Skin
5.The Relationship between Human Neutrophil Elastase and Coronary Arterial Dilatation in Kawasaki Disease .
Jun Yong SHIM ; Hee Won CHOI ; Ja Hyun HONG ; Jong Kyun LEE ; Hae Yong LEE
Journal of the Korean Pediatric Society 2003;46(9):903-908
PURPOSE: Kawasaki disease is notorious for coronary arterial complication which is usually developed as a febrile disease in early childhood. Increased polymorphonucleus(PMN) cell levels in acute phases may be associated with the pathophysiology of Kawasaki disease. We studied the relationship between coronary arterial dilatation and elastase activity which was excreted from PMN cell and roles as an important factor for vasculitis. METHODS: Ten patients diagnosed with Kawasaki disease in Yonsei University Medical Center were examined between November, 2001 and January, 2002. In addition, 15 patients with other febrile diseases were also examined. Echocardiography was done in patients with Kawasaki disease on the first day of admission and four weeks after the onset of the disease. At each time, venous samples were drawn and separated into plasma and leukocytes. In patients with other febrile disease, samples were drawn on admission. Elastase activities in plasma and neutrophil extracts were measured. RESULTS: The significant increased plasma elastase activity, 6.19+/-0.74 U/mL, found in Kawasaki disease patients compared with the other febrile disease patients, 4.86+/-1.17 U/mL(P<0.05). And there was no significance between the above two diseases in terms of the elastase activity in neutrophil extracts. The relationship between initial elastase activity and the coronary arterial complication which was shown in subacute phase wasn't significant. CONCLUSION: Plasma elastase activity was increased in Kawasaki disease significantly, but the initial plasma elastase activity in the acute phase could not reflect the range of coronary arterial complication.
Academic Medical Centers
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Dilatation*
;
Echocardiography
;
Humans*
;
Leukocyte Elastase*
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Leukocytes
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Mucocutaneous Lymph Node Syndrome*
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Neutrophils*
;
Pancreatic Elastase
;
Plasma
;
Vasculitis
6.A Case of Coronary Stenting in the Management of Myocardial Ischemia Caused by Myocardial Bridging.
Seung Hyuk CHOI ; Sang Jun SHIM ; Ki Hyun BYUN ; Donghoon CHOI ; Won Heum SHIM
Korean Circulation Journal 2001;31(9):940-944
Myocardial bridging is defined as a condition where a segment of a major epicardial coronary artery running intramurally through the myocardium. Although this abnormality is usually regarded as an incidental finding at angiography, it has been associated with myocardial ischemia, infarction, and sudden death. Standard treatment involves beta-adrenergic receptor blockers, surgery with dissection of the overlying muscle fibers, or coronary artery bypass grafting. A few cases of the intracoronary stent implantation have been reported as an alternative treatment in individual patients with myocardial bridging. We report a case of intracoronary stenting in a severe systolic narrowing at the middle segment of the left anterior descending artery in a patient complaining of recurrent chest pain despite medical treatment.
Angiography
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Arteries
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Chest Pain
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Coronary Artery Bypass
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Coronary Vessels
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Death, Sudden
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Humans
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Incidental Findings
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Infarction
;
Myocardial Bridging*
;
Myocardial Ischemia*
;
Myocardium
;
Running
;
Stents*
7.Cerebral Aneurysms in Judicial Precedents
Kyeong Seok LEE ; Jae Jun SHIM ; Jae Hyun SHIM ; Jae Sang OH ; Seok Mann YOON
Journal of Korean Neurosurgical Society 2018;61(4):474-477
OBJECTIVE: From November 30, 2016, the Korean Government carried the revised Medical Dispute Mediation and Arbitration Act into effect. Mediation will start automatically without agreements of the defendant, when the outcome of the patient was death, coma more than a month or severe disability. Cerebral aneurysm has a definite risk of bad outcome, especially in the worst condition. Any surgical intervention to this lesion has its own high risk of complications. Recently, Seoul central district court decided 50% responsibility of the doctors who made a rupture of the aneurysm during coiling (2015Ga-Dan5243104). We reviewed judicial precedents related to cerebral aneurysms in lawsuit using a web search.METHODS: We searched judicial precedents at a web search of the Supreme Court, using the key words, "cerebral aneurysm".RESULTS: There were 15 precedents, six from the Supreme Court, seven from the High Court, and two from district courts. Seven precedents were related to the causation analysis, such as work-relationship. Five precedents were malpractice suits related bad results or complications. Remaining three precedents were related to the insurance payment. In five malpractice precedents, two precedents of the Supreme Court reversed former two precedents of the High Court.CONCLUSION: Judicial precedents on the cerebral aneurysm included not only malpractice suits, but also causation analysis or insurance payment. Attention to these subjects is needed. We also need education of the independent medical examination. To avoid medical disputes, shared decision making seems to be useful, especially in cases of high risk condition or procedures.
Aneurysm
;
Coma
;
Decision Making
;
Dissent and Disputes
;
Education
;
Expert Testimony
;
Humans
;
Insurance
;
Intracranial Aneurysm
;
Malpractice
;
Negotiating
;
Rupture
;
Seoul
8.A Case of Disappearing Symptoms Developed Repetitively in a Complete Atrioventricular Block Patient Implanted Bipolar Permanent Pacemaker After Converting It into Unipolar System.
Jun Young KWEON ; Kyo Won CHOI ; Dong Gu SHIN ; Young Jo KIM ; Bong Sup SHIM ; Hyun Woo LEE
Yeungnam University Journal of Medicine 1994;11(1):181-185
Pacemaker malfunctions are secondary to alterations of the preset pacing rate, irregular pacing failure of sensing, failure of cardiac capture or depolarization, and various combinations of these events. A 76 years old male patients was admitted due to pacemaker malfunction. 2 years ago, he was diagnosed as complete atrioventricular block. And then bipolar permanent pacemaker was implanted. Since then syncopal attack developed repetitivly. 12 lead ECG and 24 hour holter moniter monitoring, revealed pacing and sensing failure, thus we converted bipolar system into unipolar system. since then syncopal attack did not developed again.
Atrioventricular Block*
;
Electrocardiography
;
Humans
;
Male
9.Risk Factors for Urinary Stone Formation in Male Patients with Spinal Cord Injury: A 17-Year Follow-Up Study.
Won Jun CHOI ; Ja Hyun KU ; Hong Bang SHIM
Korean Journal of Urology 2006;47(8):807-812
PURPOSE: This study was initiated to establish the hazard ratios for risk of urinary stone formation in chronic spinal cord injury (SCI) patients. MATERIALS AND METHODS: A total of 140 male patients who were injured before 1987 were eligible for this investigation and they were followed up on a yearly basis from January 1987 and December 2003. RESULTS: Over the 17 years, 39 patients (27.9%) and 21 patients (15.0%) were diagnosed with bladder and renal stones for a total of 59 and 25 episodes, respectively. On multivariate analysis, bladder stone was more common for the patients who were injured at 24 years old or older than is was for those patients who were injured at less than 24 years old (odds ratio [OR]: 2.490; 95% confidence interval [CI]: 1.092-5.677; p=0.030). In another model, the patients with complete injury had a greater risk of renal stone formation than those with incomplete injury (OR: 4.095; 95% CI: 1.295-12.944; p=0.016). We also found that renal stone was more common for the patients with urethral catheterization (UC) than for the patients who could spontaneous void (OR: 5.668; 95% CI: 1.306-24.604; p=0.021), and for patients with bladder stone than for those without bladder stone (OR: 4.678; 95% CI: 1.447-15.126; p=0.010). CONCLUSIONS: Injury characteristics are important for the development of urinary stone in chronic traumatic SCI patients. In addition, our findings suggest that for the cases who cannot undergo intermittent catheterization or when the bladder cannot empty spontaneously, suprapubic cystostomy is better than UC is regards to renal stone formation in this population.
Catheterization
;
Catheters
;
Cystostomy
;
Follow-Up Studies*
;
Humans
;
Male*
;
Multivariate Analysis
;
Risk Factors*
;
Spinal Cord Injuries*
;
Spinal Cord*
;
Urinary Bladder
;
Urinary Bladder Calculi
;
Urinary Calculi*
;
Urinary Catheterization
;
Urinary Catheters
;
Young Adult
10.The Role of CT Discography in Far Lateral Disk Herniation.
Young Chul KIM ; Young Sook KIM ; Jae Hee OH ; Hyun Shim KOH ; Seung Soo YUN ; Jun Kyun PARK
Journal of the Korean Radiological Society 1995;33(5):681-685
PURPOSE: To evaluate the value and the radiologic findings of CT discography in the diagnosis of the far lateral disk herniation. MATERIALS AND METHODS: We retrospectively reviewed 7 cases of surgically proven far lateral lumbar disc herniation. CT discography was performed for all cases. Four cases underwent conventional CT and three cases MRI as a primary diagnostic imaging method. Far lateral diac herniation was divided into 3 groups by location;Intraforaminal herniation, extraforaminal herniation, and mixed type. We analyzed the findings of CT discography including location and extent of far lateral disc herniation. RESULTS: In all 7 cases, CT discography clearly demonstrated the filling of contrast media in laterally-protruded disc material. Intraforaminal and extraforminal types were seen in 2 cases each, and mixed type in 3 cases. Subligamentous herniated nucleus pulposus was present in 6 cases and extruded disc in 1 case. Far lateral disc herniation was located at L4-5 in 5 cases and L5-S1 in 2 cases. CONCLUSION: CT discography can help establishing accurate preoperative diagnosis for far lateral disc herniation.
Contrast Media
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Diagnosis
;
Diagnostic Imaging
;
Magnetic Resonance Imaging
;
Retrospective Studies