1.A Case of Cerebral Venous Thromobosis Associated with Postsplenectomy Thrombocytosis.
Ki Hyun CHO ; Eui Ju SON ; Sei Jong KIM
Journal of the Korean Neurological Association 1990;8(2):353-356
Cerebral venous thrombosis is come from thromboplebitis of infectious origin and bland occlusion of cerebral vein by various causes. Although the main cause of cerebral venous thrombosis is thrombophlebitis, the bland occlusion causes it infrequently as a form of an infarct state. We report a case of cerebral venous infarction caused by splenectomy induced thrombocytosis.
Cerebral Veins
;
Infarction
;
Splenectomy
;
Thrombocytosis*
;
Thrombophlebitis
;
Venous Thrombosis
2.Angiokeratoma Circumscriptum: Successful Treatment with the Flashlamp Pulsed Tunable Dye Laser.
Sang Wook SON ; Seung Hyun HONG ; Gil Ju YI ; Hae Jun SONG ; Chil Hwan OH
Korean Journal of Dermatology 1998;36(1):152-155
Angiokeratoma circumscriptum is present at birth or early childhood and is an uncommon dermatosis characterized by papules and small nodules that may coalesce to form plaques. Histopathologically, there are varying degrees of hyperkeratosis, papillomatosis, and irregular acanthosis. In the papillary dermis, greatly dilated capillaries are observed, The acanthotic epidermis encircles the vascular spaces(blood cysts) where, occasionally, organized thrombi may be found. The use of pulsed-dye lasers to treat cutaneous vascular lesions is based on the theory of selective photothermolysis. We report a case of an angiokeratoma circumscriptum in an 48-year-old woman for whom the flashlamp pulsed tunable dye laser proved to be a highly successful means of treatment.
Angiokeratoma*
;
Capillaries
;
Dermis
;
Epidermis
;
Female
;
Humans
;
Lasers, Dye*
;
Middle Aged
;
Papilloma
;
Parturition
;
Skin Diseases
3.Periodontal Management strategies for the future in Korea.
The Journal of the Korean Academy of Periodontology 1997;27(3):533-547
In periodontics, much progress was made in the understanding of periodontal disease from 1960s to 1980s and in prevention and management of periodontal disease since the end of 1980s. This presentation will discuss about the prevalence of periodontal disease, treatment need, and provision of periodontal treatment in Korea, and how we could manage the periodontal disease efficiently in the future. According to an epidemiological study in Korea, periodontal disease(including gingivitis) was present in 82% of general population and periodontitis in 30-40% in adult population over 30y and juvenile periodontitis in 0.1% of adolescents. If we consider that at least 17% of these patients may have recurrent or refractory forms, there is obviously an abundance of disease that needs treatment. As a result of increase in life expectancy, senile population over 65 y will be increased from 6% in 1996 to 6.9% in 2000, and tooth retention rate and periodontal treatment need are expected to increase. Periodontists need all the help they can get from the general dentists to control periodontal disease. As for provision, postgraduate course in periodontics started in 1957 in Korea and produced over 700 specialized dentists in periodontics. One report indicated that the periodontists as well as general practitioners did periodontal therapy on only a few periodontal patients, because of specific control by current medical insurance system in Korea. Comprehensive periodontal examination is rarely done in local dental clinic. Therefore, enhancement of periodontal care in medical insurance system and education of simplified periodontal examination such as Periodontal Screening & Recording will make dentists diagnose and manage the management of adult patients is based on the recognition that there are multiple diseases, including gingivitis, chronic adlt periodontitis, and other more aggressive forms of periodontitis, and requires the earliest possible recognition of these three disease categories. In this presentation, we discuss practical approach using PSR to diagnose, manage and refer the patients, to facilitate the separation of the simple from the complex and the predictable from the unpredictable form of periodontal diseases and to integrate diagnostic and therapeutic techniques into private practice today.
Adolescent
;
Adult
;
Aggressive Periodontitis
;
Dental Clinics
;
Dentists
;
Education
;
Epidemiologic Studies
;
General Practitioners
;
Gingivitis
;
Humans
;
Insurance
;
Korea*
;
Life Expectancy
;
Mass Screening
;
Periodontal Diseases
;
Periodontics
;
Periodontitis
;
Prevalence
;
Private Practice
;
Tooth
4.An In-vitro Evaluation of Intratracheal Pulmonary Ventilation Physics.
Korean Journal of Anesthesiology 1994;27(1):66-74
No abstract available.
Pulmonary Ventilation*
5.Observations of Arrhythmias by 24 Hour Ambulatory ECG Monitoring in Early Convalescent Phase of Acute Myocardial Infarction.
Hyun Ju SON ; Yang Hee LIM ; Sung Sook PARK ; Gil Ja SHIN ; Woo Hyung LEE
Korean Circulation Journal 1986;16(4):509-514
In order to observe the arrhythmia which occured in early convalescent phase of acute myocardial infarction, a 24 hour ambulartory ECG monitiring was performed in 15 patients who is admitted at dept of Int Medicine, Ewha Womans University hospital from Aug. 1985 to Sept. 1986. during 7.5+/-3.4 days after admission. In all cases one or more of the following arrhythmias were observed;atrial premature beat, ventricular premature beat(VPB), transient paroxysmal ventricular thchycardia, atrial fibrillation, sinus arrest and junctional beat. Of 15 cases, 11(77.3%) had VPB's:Simple VPB's in 4 cases(26.7%) and complex VPB's(6.52+/-2.52)(P<0.05). But there were no difference of premature and abberancy index between complex VPB's and simple VPB's(P>0.1). In addition, we compaired the arrhythmias in CCU with those of early convalescent phase of acute myocardial infarction. But there was no correlation between them.
Arrhythmias, Cardiac*
;
Atrial Fibrillation
;
Cardiac Complexes, Premature
;
Electrocardiography*
;
Female
;
Humans
;
Myocardial Infarction*
6.Improving order-to-antibiotic time by operating an automated dispensing cabinet system in the emergency medical center
Dong Geun SON ; Wook Jin CHOI ; Hyun Kyung YOON ; Hyun Ju HWANG ; Eun Ji PARK ; Soo Yeon LEE ; Seo Yeong SON ; Chang Geun OH
Journal of the Korean Society of Emergency Medicine 2022;33(4):421-421
7.The Efficacy of Fixed Dose Rosiglitazone and Metformin Combination Therapy in Poorly Controlled Subjects with Type 2 Diabetes Mellitus.
Tae Seo SOHN ; Jee in LEE ; In Ju KIM ; Kyung Wan MIN ; Hyun Shik SON
Korean Diabetes Journal 2008;32(6):506-512
BACKGROUND: Obese type 2 diabetic subjects are recently increasing in Korea, indicating the importance of insulin resistance rather than insulin secretory defects in the pathophysioloy of type 2 diabetes. The purpose of this study is to evaluate the safety and efficacy of fixed dose rosiglitazone/metformin combination therapy in poorly controlled subjects with type 2 diabetes mellitus. METHODS: 12 type 2 diabetic subjects who had a HbA1c > 11% or fasting plasma glucose > 15 mmol/L were included. After a 2 week screening period, the subjected took the fixed does rosiglitazone/metformin for 24 weeks. The treatment with rosiglitazone/metformin began at week 0 with an initial dose of 4 mg/1000 mg and, unless tolerability issues arose, subjects would be increased to 6 mg/1500 mg at week 4 and at week 8 to the maximum dose of 8 mg/2000 mg. The primary object of this study was to characterize the magnitude of HbA1c reduction from baseline after 24 weeks of rosiglitazone and metformin treatment in poorly controlled type 2 diabetics. RESULTS: The mean age of the subjects was 48.9 +/- 10.6 years old, body mass index was 25.0 +/- 3.5 kg/m2, HbA1c was 12.0 +/- 1.0%, and fasting plasma glucose was 16.3 +/- 3.1 mmol/L. HbA1c was reduced to 7.54 +/- 1.45% and fasting plasma glucose reduced to 7.96 +/- 2.38 mmol/L at week 24. The proportion of HbA1c responder who showed the reduction from baseline of > or = 0.7% or HbA1c < 7% was 11 among 12 subjects (91.7%). 41% of the subjects (5 among 12 subjects) achieved HbA1c level < 7.0% and 75% (9 among 12 subjects) achieved HbA1c level < 8.0%. CONCLUSIONS: In this study, rosiglitazone and metformin combination therapy was effective in glycemic control in poorly controlled subjects with type 2 diabetes mellitus.
Body Mass Index
;
Diabetes Mellitus, Type 2
;
Fasting
;
Glucose
;
Insulin
;
Insulin Resistance
;
Korea
;
Mass Screening
;
Metformin
;
Plasma
;
Thiazolidinediones
8.Miliary Tuberculosis: HRCT Findings in 14 Patientst.
Byung Su KIM ; Soon Kew PARK ; Kun Il KIM ; Hyun Ju SON ; Dong Hi JUHNG ; Suk Hong LEE
Journal of the Korean Radiological Society 1994;31(5):863-867
PURPOSE: To evaluate high-resolution CT(HRCT) findings of the miliary tuberculosis and their significancy. MATERIAL AND METHOD: We retrospectively studied clinical records, HRCT and chest radiographs of 14 patients with miliary tuberculosis. RESULTS: On HRCT, nodules were seen in all 14 cases, 10 of them evenly, and 4 were irregularly distributed. The size of each nodule was less than 1 mm in 7 cases, 1 --2ram in 6 cases, and 3mm or more in 1 case. The ground - glass opacity was accompanied in 8 cases, and fine reticular opacity was also noted in 8 cases. Other associated findings were pleural effusion (n=4), hilar and mediastinal lymphadenopathy (n=3), consolidation of the exudative tuberculosis (n=4). CONCLUSION: HRCT findings of miliary tuberculosis are diffusely distributed micronodules of variable size, less than 5mm in diameter. The ground-glass opacity can be combined.
Glass
;
Humans
;
Lymphatic Diseases
;
Pleural Effusion
;
Radiography, Thoracic
;
Retrospective Studies
;
Tuberculosis
;
Tuberculosis, Miliary*
9.The Effect of Rosiglitazone and Metformin Therapy, as an Initial Therapy, in Patients with Type 2 Diabetes Mellitus.
Tae Seo SOHN ; Jee In LEE ; In Ju KIM ; Kyung Wan MIN ; Hyun Shik SON
Korean Diabetes Journal 2008;32(5):445-452
BACKGROUND: Type 2 diabetes is usually preceded by a long and clinically silent period of increasing insulin resistance. The purpose of this study is to demonstrate that rosiglitazone and metformin fixed-dose combination therapy (RSG/MET) will safely and effectively control glycemia as a first line of oral therapy, better than rosiglitazone (RSG) or metformin (MET) monotherapy in Korean type 2 diabetes patients. METHODS: This study was a 32-week, multicenter, randomized, double-blind study. Twenty-seven type 2 diabetes patients (males 14; females 13) were included and randomly divided into the rosiglitazone, metformin group, or rosiglitazone /metformin combination groups. The primary objective of this study was to determine the change in HbA1c from baseline (week 0) to week 32. The secondary end-points were to determine changes in fasting plasma glucose (FPG) and homeostasis model assessment insulin resistance (HOMA-IR), from baseline to week 32. Other cardiovascular risk markers were also assessed. RESULTS: At week 32, there were significant reductions in HbA1c and FPG, in all three treatment groups. There was no statistical difference in HbA1c among the three groups, but the decrease in FPG in the RSG/MET group was statistically significant compared to the MET group (P < 0.05). RSG/MET significantly reduced HOMA-IR at week 32 compared to baseline, but there was no difference among the three groups. RSG/MET significantly decreased high-sensitive C-reactive protein (hs-CRP) value at week 32, compared to baseline. There were increases in adiponectin from baseline to week 32 in the RSG and RSG/MET groups, and the increase in the RSG/MET group was statistically significant compared to that of the MET group (P < 0.05). At week 32, there was a significant decrease in plasminogen activator inhibitor-1 (PAI-1) in all three treatment groups, but no statistically significant difference among them. The RSG/MET group significantly decreased in terms of urinary albumin-creatinine ratio at week 32, compared to baseline. CONCLUSIONS: In this study, rosiglitazone and metformin combination therapy was effective in glycemic control as an initial therapy, and it improved cardiovascular risk markers in Korean type 2 diabetes patients.
Adiponectin
;
C-Reactive Protein
;
Diabetes Mellitus, Type 2
;
Double-Blind Method
;
Fasting
;
Female
;
Glucose
;
Homeostasis
;
Humans
;
Insulin Resistance
;
Metformin
;
Plasma
;
Plasminogen Activators
;
Thiazolidinediones
10.Clinical Experience on the Visual Rehabilitation of Low Vision Patients.
Jae Hyun SON ; Nam Ju MOON ; Bon Sool KOO
Journal of the Korean Ophthalmological Society 1995;36(2):324-330
We evaluated the efficacy of the optical and non-optical low vision aids on the basis of our 31 low vision patients, whose visual acuities were not corrected with the conventional glasses nor operations. Out results were following that the improved visual acuities by the low vision aids were stastically significant(p<0.01, paired t-test), and meet their needs. We think the optical and non-optical low vision aids are required to rehabilitate the visually impaired patients.
Eyeglasses
;
Glass
;
Humans
;
Rehabilitation*
;
Vision, Low*
;
Visual Acuity