1.A Case of Localized fibrous tumor of Pelvic Cavity.
Chun Ju LEE ; Byung Jin JANG ; Hyun Jun PARK ; Sung Yong KIM ; Hae Young PARK
Korean Journal of Urology 2001;42(1):124-126
Localized fibrous tumor is an uncommon submesothelial origin tumor found in pleura most commonly. Sixty five-year-old man with right lower quadrant pain was admitted. He was treated with resection of tumor and was diagnosed as localized fibrous tumor of pelvic cavity. He is now being followed up without any evidence of recurrence for 34 months. This case is presented with reviewing references.
Pleura
;
Recurrence
2.A Case of Lung Metastasis of Testicular Yolk Sac Tumor.
Ho Ju YOON ; Hyun Kyung CHO ; Jung Sik CHUN ; Chang Kyu OH ; Mahn Kyoo YANG
Journal of the Korean Pediatric Society 1982;25(12):1275-1279
No abstract available.
Endodermal Sinus Tumor*
;
Lung*
;
Neoplasm Metastasis*
;
Yolk Sac*
3.Prevalence of Metabolic Syndrome and Its Components in Adult Women
Journal of Korean Biological Nursing Science 2018;20(4):261-269
PURPOSE: The purpose of this study was to investigate the prevalence of metabolic syndrome and diagnostic components in adult women. METHODS: The subjects of this study were 12,016 women that were aged twenty years or older and underwent an annual health check-up for National Health Insurance Service (NHIS) from 2009 to 2013. Data including blood pressure, waist circumstance, fasting glucose, triglyceride, and high density lipoprotein cholesterol (HDL-C) were received from the NHIS. This data was analyzed through the use of descriptive statistics, χ2-test, and multiple logistic regression. RESULTS: The prevalence of metabolic syndrome and diagnostic components increased with age. In the five diagnostic components of the metabolic syndrome, the prevalence of low HDL-C was highest in 20s to 40s. The prevalence of high blood pressure was highest in the people aged fifty or older. The risk of metabolic syndrome in 2013 was higher in women with abnormal diagnostic component of metabolic syndrome in 2009 and highest in women with abnormal waist circumstance in 2009. CONCLUSION: There was a need to investigate the prevalence of metabolic syndrome components according to age. Education on metabolic syndrome was required for those that had one or two abnormal diagnostic components. The risk of abdominal obesity related to metabolic syndrome needs to be emphasized. Moreover the education for management of abdominal obesity also needs to be emphasised.
Adult
;
Blood Pressure
;
Cholesterol, HDL
;
Education
;
Fasting
;
Female
;
Glucose
;
Humans
;
Hypertension
;
Logistic Models
;
National Health Programs
;
Obesity, Abdominal
;
Prevalence
;
Triglycerides
4.Effects of IFN - gamma on Spheroid and Raft Culture of Squamous Cell Carcinoma of the Head and Neck.
Seung Ju LEE ; Chun Dong KIM ; Tae Young KOH ; Keun Ho CHANG ; Chae Seo RHEE ; Seong Jun YOON ; Sagn Goo LEE ; Hyun Ju LEE ; Kwang Hyun KIM
Journal of the Korean Cancer Association 1998;30(3):573-582
PURPOSE: To establish new in vitro model systems that better reflect in vivo condition, multicellular tumor spheroids(MTS) and raft culture were developed using cell lines of squamous cell carcinoma(SCCHN) of the head and neck. In these 3-dimensional systems, the expression of cell surface molecules which are important for modulation of physiology of tumor cells were studied with or without the treatment of interferon(IFN)-gamma. MATERIALS AND METHODS: Four SCCHN cell lines were used for MTS and raft culture. The effects of interferon-gamma on SCCHN cells were examined by immunohistochemistry. RESULTS: All cell lines formed MTS, but only Tu-138 showed a good stratification at the air-liquid interface in the raft culture system. Immunohistochemical studies of MTS using monoclonal antibodies revealed a strong staining for MHC class I, no staining for MHC-DR, a weak patch expression of ICAM-1 and a central strong staining for integrin a 6. Staining patterns were similar for the raft cultures except integrin a 6(intense full-thickness positivity). In both systems, IFN-gamma enhanced the expression of MHC-DR and ICAM-1. No significant change was found in the expression of MHC class I and integrin a 6. CONCLUSIONS: MTS and raft culture system were established successfully from the SCCHN cell lines. IFN-gamma can modulate the surface molecules of tumor cells in the 3-dimensional culture systems.
Antibodies, Monoclonal
;
Carcinoma, Squamous Cell*
;
Cell Line
;
Head*
;
Immunohistochemistry
;
Intercellular Adhesion Molecule-1
;
Interferon-gamma
;
Neck*
;
Physiology
5.Comparative study for diagnosis of pelvic malignancy between serum CA 125 and transvaginal sonogram.
Hyun Mee RYU ; Hye Sung MOON ; Young Ju KIM ; Kyung Hee CHOI ; Sun Hee CHUN ; Bock Hi WOO
Korean Journal of Obstetrics and Gynecology 1993;36(7):2899-2912
No abstract available.
Diagnosis*
6.The Prevalence, Awareness, Treatment, and Control of Hypertension, and Related Factors in Rural Korea.
Yong Chan HA ; Hyun Ju CHUN ; Hae Kyoung HWANG ; Byung Sung KIM ; Jang Rak KIM
Korean Journal of Preventive Medicine 2000;33(4):513-520
OBJECTIVES: To estimate the prevalence of hypertension, rates of awareness, treatment modalities, and control of hypertension, and also to identify factors in rural Korea that are related to these aspects of hypertension. METHODS: A cross-sectional survey, including blood pressure(BP) measurements and interviews, investigating the variables in the health belief model was performed from August to November, 1999 on 1,426 (79.4%) study subjects out of 1,797 registered residents over 30 years old in Ibansong-Myun, Chinju City. A second survey was performed from January to March, 2000 on 376 (80.0%) subjects out of 470 hypertensive (or suspected hypertensive) subjects found in the first survey. Two BP readings were taken in each survey using a standard mercury sphygmomanometer. Hypertension was defined as either a BP reading < 140/90 mmHg in both surveys, or as subjects on oral hypertensive medication. RESULTS: Estimated hypertension prevalence was 24.9% for men, and 30.4% for women. Rates of hypertension awareness, treatment (the regular use of oral hypertensives), and control (reduction of BP to <140/90 mmHg) were 52.5%, 34.4%, and 12.9%, respectively. The factors related to lower hypertension awareness in the logistic regression analysis were male gender, farming occupation, and higher perceived barrier to medical treatment (those for whom visiting health professionals is a burden). CONCLUSIONS: To improve the low awareness, treatment, and control of hypertension, a more active and out-reaching hypertension control program, including routine BP measurements for every visitor to primary care facilities, is needed in rural Korea.
Adult
;
Cross-Sectional Studies
;
Female
;
Gyeongsangnam-do
;
Health Occupations
;
Humans
;
Hypertension*
;
Korea*
;
Logistic Models
;
Male
;
Occupations
;
Prevalence*
;
Primary Health Care
;
Reading
;
Sphygmomanometers
7.A STUDY ON THE FRACTURE STRENGTH OF THE IPS-EMPRESS CERAMIC CROWN ACCORDING TO MARGIN TYPE.
Hyun soo KIM ; Tae Hun JU ; Sang Chun OH ; Jin Keun DONG
The Journal of Korean Academy of Prosthodontics 1997;35(2):296-307
The purpose of this study was to compare the fracture strength of the IPS-Empress ceramic crown according to margin types such as bevel, shoulder, ronuded shoulder, schouler with bevel, rounded shoulder with bevel and bevel with groove. After 10 metal dies were constructed for each group, the IPS-Empress ceramic crown were fabricated and each crown was cemented on each metal die with Bistite resin cement. The cemented each crown was cemented on each metal die with Bistirte resin cement. The cemented crowns mounted in the resting jig were inclined 30 degree and universal testing machine (Zwick 1456 41, Zwick Co., Germany) was used to measure the fracture strength. The obtained result were as follows : 1. The fracture strenght of the crown with reounded shoulder was the hightest of all. The mean fracture strength was 484N in rounded shoulder, 357N in bebel, 341N in rounded shoulder with bevel, 300N in shoulder with bevel, 280N in shoulder and 275N in bevel with groove. 2. The fracture strength of rounded shoulder was statistcally different from those of shoulder with bevel, shoulder and bevel with groove. 3. In the strain at fracture, there was no significant difference among each group. 4. The fracture mode of the crown was simila and most of fracture line began at the loading area and extended throught proximal surface perpendicularly to the margin, irrespective of margin type.
Ceramics*
;
Crowns*
;
Resin Cements
;
Shoulder
8.Frequency, Intensity and Daily Life Distress of Urinary Dysfunction in Women with Cervical Cancer after Radical Hysterectomy.
Nami CHUN ; Gie Ok NOH ; Hyun Ju SONG ; Sang Hee KIM
Journal of Korean Academy of Nursing 2016;46(3):400-408
PURPOSE: This study was done to identify frequency, intensity of urinary dysfunction and daily life distress in women after a radical hysterectomy for cervical cancer. METHODS: One hundred and fifty seven women who had undergone a radical hysterectomy and one hundred and sixty five women as healthy controls completed questionnaires on intensity of urinary dysfunction and daily life distress caused by urinary dysfunction. RESULTS: Women with cervical cancer showed higher frequency of urinary dysfunction than healthy controls. Major urinary dysfunction for women with cervical cancer in order of frequency were night-time incontinence (odds ratio=10.39, p<.001), difficulty in starting urination, weak urine stream and sense of incomplete emptying of bladder. The highest score on intensity was difficulty in starting urination, followed by urgency, weak urine stream, daytime frequency and sense of incomplete emptying. Night-time incontinence was the urinary symptom causing the most daily life distress for cervical cancer women followed by difficulty in starting urination, urgency, sense of incomplete emptying, and night-time frequency. CONCLUSION: Results suggest that nurses should address the potential postoperative urinary complications and develop long term interventions to decrease urinary dysfunction and daily life distress for women who have had a radical hysterectomy for cervical cancer.
Female
;
Humans
;
Hysterectomy*
;
Rivers
;
Urinary Bladder
;
Urinary Bladder, Neurogenic
;
Urination
;
Uterine Cervical Neoplasms*
9.Radiotherapy of Locally Recurrent Rectal Carcinoma.
Hyeon Ju JEONG ; Young Ju SHIN ; Kwang Mo YANG ; Hyun Suk SUH ; Hachung CHUN ; Myung Za LEE
The Journal of the Korean Society for Therapeutic Radiology and Oncology 1999;17(1):36-41
PURPOSE: We reviewed the treatment results for the patients with locally recurrent rectal carcinoma. The object was to evaluate the treatment outcome and to identify the prognostic factors influencing the survival. METHODS AND MATERIALS: Twenty-eight patients with locally recurrent rectal carcinoma treated principally with external-beam radiation therapy between 1982 to 1996 in the Department of Radiation Oncology at Paik and Hanyang Hospital were reviewed retrospectively. Of these, 17 patients had initially abdominoperineal resection, 9 had low anterior resection, and 2 had local excision. No patients had received adjuvant radiation therapy for the primary disease. There were 14 men and 14 women whose ages ranged from 31 to 72 years (median age:54.5). Median time from initial surgery to the start of radiation therapy for local recurrence was 11 months (4~47 months). Radiation therapy was given with total doses ranging from 27 to 64.8 Gy (median=51.2 Gy). RESULTS: The median survival was 16.7 months. The 2-year and 5-year survival rates were 20.1%, 4.1% respectively. Upon multivariate analysis, overall survival was positively correlated with duration of intervals from initial surgery to local recurrence (P=0.039). Relief of pelvic symptoms was achieved in 17 of 28 patients (60.7%). Pain and bleeding responded in 40% and 100% of patients, respectively. CONCLUSION: Patients with locally recurrent rectal carcinoma treated with radiotherapy have benefited symptomatically, and might have increased survivals with a small chance of cure. But, patient were rarely cured (median survival:10 months, 5-year survival:less than 5%). Overall survival was positively correlated with long intervals from initial surgery to local recurrence. Future efforts should be directed to the use of effective therapy for patients with locally recurrent rectal carcinoma and adjuvant therapy for patients with rectal cancer to reduce the incidence of pelvic recurrence.
Female
;
Hemorrhage
;
Humans
;
Incidence
;
Male
;
Multivariate Analysis
;
Radiation Oncology
;
Radiotherapy*
;
Rectal Neoplasms
;
Recurrence
;
Retrospective Studies
;
Survival Rate
;
Treatment Outcome
10.The Effect of Prostaglandin and its Inhibitor on the Antibody - dependent Cellular Cytotoxicity Against Human Squamous Cell Carcinoma of the Head and Neck.
Seung Ju LEE ; Chun Dong KIM ; Keun Ho CHANG ; Kwang Hyun KIM ; Seong Jun YOON ; Sang Goo LEE ; Hyun Joo LEE ; Dae Seog HEO ; Myung Whun SUNG
Korean Journal of Immunology 1997;19(4):533-540
The effects of chimeric monoclonal antibodies (cMAbs), prostaglandin E, (PGE,), and indomethacin (INDO) on antibody-dependent cellular cytotoxicity (ADCC) against human squamous cell carcinoma of head and neck (SCCHN) cell line were examined. Using the PCI-50 SCCHN cell line as target and normal human peripheral blood mononuclear cells as effector, ADCC was enhanced by the treatment of cMAbs (1.25 p,g/ml), but was inhibited by exogenous PGE (5 X 10' M). The effects of cMAb and PGE were dose-dependent. Maximal suppression of activity occured when PGE was present during the entire 4-hr 'Cr-release assay period, whereas pretreatment of effector cells with PGE had minimal inhibitory effect after washing. These results indicate that decreased ADCC seen with SCCHN targets treated with PGE is related to post-binding events, such as binding of effector and target cells. Pre-treatment of effector cells with INDO (1 ug/ml) resulted in restoration of NK activity which was inhibited by PGE. Our in vitro results suggest that INDO can increase tumor cell killing by the reversal of the suppression for many imrnune functions by PGE.
Antibodies, Monoclonal
;
Antibody-Dependent Cell Cytotoxicity
;
Carcinoma, Squamous Cell*
;
Cell Line
;
Head*
;
Homicide
;
Humans*
;
Indomethacin
;
Neck*
;
Prostaglandins E