No abstract available.
Meconium* ; Prospective Studies* ; Statistics as Topic*

No abstract available.
Nephrotic Syndrome*

Sandifer syndrome is a rare manifestation of gastroesophageal reflux in children, occurring in association with abnormal movement of the head and neck and recurrent episodes of seizure after feeding. This syndrome may be misdiagnosed as infantile seizure and musculoskeletal disorder and may be associated with failure to thrive, anemia, aspiration pneumonia, and esophagitis. In this paper, Sandifer syndrome in a four months old male with recurrent aspiration pneumonia, apnea, and seizure after feeding is presented.
Anemia ; Apnea ; Child ; Dyskinesias ; Esophagitis ; Failure to Thrive ; Gastroesophageal Reflux ; Head ; Humans ; Male ; Neck ; Pneumonia, Aspiration ; Seizures

No abstract available.
Electroencephalography* ; Neuronal Ceroid-Lipofuscinoses ; Neurons*

PURPOSE: This study aimed to evaluate whether prophylactic extended-field pelvic radiotherapy (EF-PRT) yields better results than standard whole pelvic radiotherapy (WPRT) in patients with pelvic lymph node-positive cervical cancer treated with concurrent chemoradiotherapy (CCRT). MATERIALS AND METHODS: A total of 126 cases of stage IB-IVA cervical cancer that had pelvic lymph node involvement in magnetic resonance imaging and were treated with CCRT between 2000 and 2016 were reviewed. None of the patients had paraaortic lymph node (PALN) metastases. The patients were classified to two groups, namely, those treated with EF-PRT, including prophylactic para-aortic radiotherapy, and those treated only with WPRT. The median dose to the PALN area in patients treated with EF-PRT was 45 Gy. All patients received concurrent cisplatin-based chemotherapy. RESULTS: Overall, 52 and 74 patients underwent EF-PRT and WPRT, respectively. Patient characteristics and irradiated dose were not significantly different, except the dose to the para-aortic area, between the two groups. The median follow-up period was 75.5 months (range, 5 to 195 months). The 10-year cumulative recurrence rate of PALN for EF-PRT vs. WPRT was 6.9% and 10.1% (p = 0.421), respectively. The 10-year disease-free survival and overall survival for EF-PRT vs. WPRT were 69.7% vs. 66.1% (p = 0.748) and 71.7% vs. 72.3% (p = 0.845), respectively. Acute gastrointestinal complications were significantly higher in EF-PRT (n = 21; 40.4%) than WPRT (n = 26; 35.1%) (p = 0.046). Late toxicities were not significantly different in both groups. CONCLUSION: In this study, prophylactic radiotherapy for PALN does not have an additional benefit in patients with pelvic lymph node-positive cervical cancer treated with CCRT.
Chemoradiotherapy ; Disease-Free Survival ; Drug Therapy* ; Follow-Up Studies ; Humans ; Lymph Nodes ; Magnetic Resonance Imaging ; Neoplasm Metastasis ; Radiotherapy ; Recurrence ; Survival Rate ; Uterine Cervical Neoplasms*

Cervical large cell neuroendocrine carcinoma is rare. We experienced one case of cervical large cell neuroendocrine carcinoma with invasive mucinous adenocarcinoma in 49 years old woman. So we report the case and brief review of literature.
Adenocarcinoma, Mucinous* ; Carcinoma, Neuroendocrine* ; Cervix Uteri* ; Female ; Humans ; Middle Aged ; Mucins*

Visual disturbances are common among women with pre-eclampsia. The obstetricians should have an understanding of the various conditions associated with visual impairments. We report a case of Purtscher-like retinopathy developed after pre-eclampsia combined with acute pancreatitis. A 33-year-old primigravida with twin pregnancy was admitted to the department of obstetrics and gynecology for preterm labor and pre-eclampsia at 36+4 weeks gestation. After a cesarean section, she complained of abdominal pain and visual acuity loss. She was diagnosed with Purtscher-like retinopathy combined with acute pancreatitis after ophthalmologic examination and an abdominal computed tomography scan. Purtscher-like retinopathy, most often observed after trauma, is very rare in pre-eclampsia. In addition, while visual disturbances from other conditions are transient, it can result in persistent visual impairments. Thus, when a patient with pre-eclampsia complains of visual problems for a long period of time, obstetricians should consider an ophthalmologic evaluation and treatments during the earliest stage of the disease.
Abdominal Pain ; Cesarean Section ; Female ; Gynecology ; Humans ; Obstetric Labor, Premature ; Obstetrics ; Pancreatitis ; Pre-Eclampsia ; Pregnancy ; Pregnancy, Twin ; Retinal Diseases ; Vision Disorders ; Visual Acuity

PURPOSE: Regardless of premature rupture of membranes, the genital colonization of Ureaplasma urealyticum (Uu) in pregnant women could transmit vertical infections of their babies and cause neonatal infections, which ultimately result in infections in many other organs. The purpose of this study is to determine clinical influences on the infants born from mothers suffering genital Uu colonization. METHODS: We retrospectively reviewed the data for analysis of the 219 infants born from mothers who had been tested for genital Uu culture (about 470 cases) for past 3 years from Mar. 2006 to Jun. 2009, in East-West Neo Medical Center, Kyunghee University. The neonatal clinical manifestations such as duration of tachypnea, incidence of oxygen therapy, respiratory distress syndrome (RDS), bronchopulmonary dysplasia (BPD), sepsis, jaundice, feeding intolerance, etc. were investigated during gestational period. RESULTS: In case of positive genital Uu culture of mothers, the preterm infants (gestational period <35 weeks) had symptoms of increased heart rate within 6 hours after birth, prolonged tachypnea, short period of antibiotics use, and lower incidence of RDS and hypocalcemia. Durations of oxygen therapy, the methods and durations of positive pressure ventilation and incidences of BPD of preterm infants were not affected by maternal Uu results. The near and full term infants (gestational period > or =35 weeks) from Uu positive mothers showed the increased incidence of jaundice. CONCLUSION: It is hard to say that genital Uu colonization in pregnant women influence the near and full term infants except jaundice. However, the data analysis of the preterm infants from Uu mothers demonstrated increased heart rate within 6 hours after birth, prolonged tachypnea, short period of antibiotics use, lower incidence of RDS and hypocalcemia.
Anti-Bacterial Agents ; Bronchopulmonary Dysplasia ; Colon ; Female ; Heart Rate ; Humans ; Hypocalcemia ; Incidence ; Infant ; Infant, Newborn ; Infant, Premature ; Jaundice ; Membranes ; Mothers ; Oxygen ; Parturition ; Positive-Pressure Respiration ; Pregnant Women ; Respiratory Therapy ; Retrospective Studies ; Rupture ; Sepsis ; Statistics as Topic ; Stress, Psychological ; Tachypnea ; Ureaplasma ; Ureaplasma urealyticum

Cervical cancer is the most common female genital tract malignancy in Korean women. Although age-standardized cancer incidence rate of cervical cancer has decreased from 18.6 per 100,000 women in 1999 to 12.3 per 100,000 women in 2010 in Korea with widespread routine screening, several epidemiologic characteristics are still present. Incidence of cervical cancer still varies according to geographic area, and a significant portion of cases are detected at a locoregionally advanced stage, without significant improvement of five-year survival rate.2014-01-15 Cervical screening techniques such as the Pap smear should be the gold standard strategy to decrease incidence and to improve the survival outcomes of patients with cervical cancer. In addition, screening programs for cervical cancer should be designed, organized and directed within the context of a nationwide program for cancer control.
Female ; Humans ; Incidence ; Korea ; Mass Screening ; Uterine Cervical Neoplasms*

Although Cesarean section (CS) itself has contributed to the reduction in maternal and perinatal mortality, an undue rise in the CS rate (CSR) has been issued in Korea as well as globally. The CSR in Korea increased over the past two decades, but has remained at approximately 36% since 2006. Contributing factors associated with the CSR in Korea were an improvement in socio-economic status, a higher maternal age, a rise in multiple pregnancies, and maternal obesity. We found that countries with a no-fault compensation system maintained a lower CSR compared to that in countries with civil action, indicating the close relationship between the CSR and the medico-legal system within a country. The Korean government has implemented strategies including an incentive system relating to the CSR or encouraging vaginal birth after Cesarean to decrease CSR, but such strategies have proved ineffective. To optimize the CSR in Korea, efforts on lowering the maternal childbearing age or reducing maternal obesity are needed at individual level. And from a national view point, reforming health care system, which could encourage the experienced obstetricians to be trained properly and be relieved from legal pressure with deliveries is necessary.
Cesarean Section/*statistics & numerical data/trends ; Data Collection ; Female ; Humans ; *Insurance, Health ; Insurance, Liability ; Maternal Age ; Obesity/epidemiology ; Pregnancy ; Pregnancy, Multiple/statistics & numerical data ; Republic of Korea ; Social Class ; Vaginal Birth after Cesarean/*statistics & numerical data/trends